• Journal of the Korean Society of Environmental Restoration Technology
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• v.8 no.6
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• pp.59-68
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• 2005

This study was carried out to investigate soil properties, ordination, and vegetation of the coastal sand dune in Sinduri, Taean-Gun. 1. The Orobanche coerulescens and Ixeris repens that are a peculiar species were found in Sinduri coastal sand dune and the Salix purpurea var. japonica that is an endemic species of korea was found in that place. The plant communities was categorized into seven groups, such as Rosa rugosa community, Vitex rotundifolia communit, Carex kobomugi community, Imperata cylndrica var. koenigii community, Carex pumila community, Artemisia capillaris community, and Calamagrostis epigeios community. 2. The soil organic matter, total nitrogen, available phosphorous concentrations, and cation exchange capacity were lower in the study sites than in forest soil of seashore. There was little difference in soil exchangeable Ca, Mg, and K concentrations between in the study site and in the forest soil of seashore. The soil pH was ranged from 5.69 to 7.63. The soil texture in the study site was sand or loamy sand. 3. The results of the correlation between Sinduri coastal sand dune community and environmental factor are as follows; the soil pH was the most effect to the community distribution, and CEC, total nitrogen, soil organic matter, and the amount of silt in soil have some correlation with community distribution. 4. The results of the correlation between Sinduri coastal sand dune community and soil characteristics are as follows; the Calamagrostis epigeios community was found in area that have high soil moisture content; the Rosa rugosa community was found in area that have high soil CEC, organic matter concentration, and total nitrogen concentration, and low soil pH; the Vitex rotundifolia community, Carex kobomugi community, and Artemisia capillaris community were found in area that have low soil CEC, organic matter concentration, and total nitrogen concentration, and high soil pH; the Imperata cylndrica var. koenigii community and Carex pumila community were found in area that have medium soil CEC, organic matter concentration, total nitrogen concentration, and soil pH.

• Journal of Food Hygiene and Safety
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• v.35 no.4
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• pp.354-364
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• 2020

For this paper we analyzed heavy metals including lead, cadmium, arsenic and mercury, and conducted risk assessment on 171 types of herbal medicines used as foods and drugs distributed in Seoul's Yangnyeongsi and Kyungdong (Gyeongdong) herbal medicine markets. The concentrations of the heavy metals were measured by the ICP-MS and a mercury analyzer. The detection ranges of the lead, cadmium, arsenic and mercury were found to be ND-4.719 mg/kg, ND-1.019 mg/kg, 0.002-8.696 mg/kg and ND-0.058 mg/kg, respectively. Artemisiae Capillaris Herba exceeded the standards of the MFDS (Ministry of Food and Drug Safety) for cadmium items, and Actinidiae Ramulus et Fulium et Fructus Vermicultus exceeded the standards for arsenic items. The non-carcinogenic risk assessment showed that there were no items exceeding 1 and that they were safe. The risk of carcinogenicity to lead was below 10^-6 in all items and was evaluated as safe. The risk of carcinogenicity of arsenic was almost all in the range of 10^-4 to 10^-6. All %PTWI are considered to be safe below 100.

• Korean Journal of Pharmacognosy
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• v.36 no.4 s.143
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• pp.338-343
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• 2005

Inflammatory mediators such as interleukin-1 (IL-1), tumor necrosis $factor-{\alpha}\;(TNF-{\alpha}),\;interferon-{\gamma}\;(IFN-{\gamma})$ and lipopolysaccharide (LPS) are thought to play major roles in joint diseases such as a rheumatoid arthritis (RA), and there is considerable evidence playing a role for these cytokines in osteoarthritis (OA). Therefore, we have studied the effects on anti-inflammation and analgesic by ethyl acetate fraction from 70% ethanol extract of Artemisia capillaries (EAC). As a positive control, apigenin, which is known as an anti-inflammatory agent as an iNOS inhibitor, was used and showed the dose-dependent inhibitory effect. EAC showed strong inhibitory efficacy against cytokine-induced proteoglycan degradation, $PGE_2$ production, nitric oxide (NO) production, and matrix-matalloproteinases (MMPs) expression in rabbit articular chondrocyte. In the writhing test induced by acetic acid, EAC $(200{\sim}400\;mg/kg)$ exhibited a dose-dependent inhibition of writhing. The results indicate that EAC have anti-inflammatory and analgesic activities, and could be a good herbal medicine candidate for curing of RA and/or OA.

• The Journal of Korean Medicine
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• v.30 no.2
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• pp.127-132
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• 2009

Objectives: This study aimed to investigate the stability of a decoction using three herbal plants and their major components according to the storage conditions and periods. Materials and Methods: A three-herb mixture (1:1:1) of Glycyrrhiza uralensis Fischer, Artemisia capillaris Thunberg, and Poncirus trifoliata Rafinesqui was decocted and kept at room temperature ($25{\pm}2^{\circ}C$) or cold temperature ($4^{\circ}C$) for 0, 2, 4 or 8 weeks in liquid form in a plastic pack under dark conditions. At time points given, they were lyophilized. 200 mg of powdered samples were dissolved in 1 mL of 90% methanol and then applied to a high performance thin layer chromatography (HPTLC) with glycyrrhizin, 6,7-dimethoxycoumarin or poncirin for quantitative or qualitative analysis. Results: There were no gross changes in HPTLC-based compositional band-patterns of the three herbal mixture according to the storage conditions and period. The major components of each herb, glycyrrhizin, 6,7-dimethoxycoumarin and poncirin, showed slight time-dependent reduction in their contents both at room and cold temperature for 8 weeks. Conclusion: We could conclude that the current herbal decoction is generally safe for the stability at both RT or CT for at least 8 weeks. Nevertheless, we proposed that further advanced studies are required for more multiple herbal mixtures and longer storage periods.

• Journal of Forest and Environmental Science
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• v.16 no.1
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• pp.50-68
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• 2000

This study was to estabilish the composition and vegetation of vascular plants on natural mashes in Wondae-ri(710m: $37^{\circ}$ 58' 30" N, $128^{\circ}$ 12' 15" E), This work was conducted from April to October, 1999. Vascular plants were composed of 71 families, 175 genera, 228 species, 1 subspecies, 33 varieties and 3 formae, totaling 265 taxa. Among the investigated vascular plants, 19 families, 24 genera, 31 species, 5 varieties, 1 formae, totaling 37 taxa (13.9%) were hydrophytes and hygrophytes. The forest vegetation was classified into 1 community and 2 subcommunities ; A. Phragmites japonica community A-1. Salix gracilistyla-Impatiens noli-tangere subcommunity A-2. Spiraea prunifolia var. simpliciflora-Artemisia capillaris subcommunity.

• Journal of Haehwa Medicine
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• v.22 no.1
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• pp.129-143
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• 2013

This study was conducted to investigate the residue amount of pesticide on the 41 medicinal herbs in Daejeon area. This study was carried out to monitor the current status of pesticide residues in commercial medicinal herbs for sale of food use in 2012. It was performed using GC/ECD, GC/NPD, HPLC to analyze pesticides residues. Residues of 283 pesticides were analyzed by a simultaneous multiresidue method in 41 medicinal herbs being on sale in Daejeon. The medicinal herbs detected pesticides in 10 of 41 cases, showed a detection rate of 24.39%. The medicinal herbs which exceed the maximum residue limit were five cases as Cnidii Rhizoma, Osterici Radix, Artemisiae Capillaris Herba, Zizyphi Fructus and Alismatis Rhizoma. And pesticide residue of Cnidii Rhizoma and Alismatis Rhizoma exceeds the limit standard presented in only medicine use of KFDA. The residual pesticides which had the high detection rate were Chlopyrifos, Tebuconazole and Endosulfan in the detection of medicinal herbs. For further research, standards of Pesticide Residues in medicinal herbs should be added and more research of pesticide residues in medicinal herbs required. And standards of pesticide residues in medicinal herbs should be applied equally as medicines and food.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.6 no.6
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• pp.29-40
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• 2003

Shindoori dune, about 2,000,000$m^2$ in area, is located in the west of the middle area in Korea. Around the sand dune, many diagnostic plants and animals are populated, so it is considered a very important ecosystematic area. This study was carried out to establish for conservation and restoration in Shindoori dune. Our surveys have been accomplished from October, 2002 to September, 2003. Plant communities formed around the sand dune in Shindoori were divided into several patterns and analysed. They have been divided into 9 communities. Community A : Carex pumila community, B : Carex kobomugi community, C : Elymus moWs community, D : Imperata cylindrica var. koenigii community, E: Rosa rugosa community, F: Ischaemum anthephoroides community, G: Vitex rotundifolia community, H : Lathyrus japonica community, I : Oenothera biennis community. The flora surveyed in these communities was constituted of 19 families, 44 genera, 8 varieties, and 40 species. Wild plants such as Calystegia soldanella, Artemisia capillaris, Avena fatua, Mertensia asiatica, Glehnia littoralis and Zoysia sinica were mostly light loving plants and higher resistant plants against the salty wind. Our result from the ranking all surveyed areas by the Bray-Curtis ordination method was very similar to the results from phytosocialogical table work.

• Korean Journal of Pharmacognosy
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• v.35 no.3 s.138
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• pp.229-232
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• 2004

Chronical intake of alcohol can cause alcoholic fatty liver. Fatty liver is caused by fat infiltration: the state of high rate of fat in liver cells and by losing the balance between the synthesis and the secretion of fatty acid. It could be developed into liver necrosis and cirrhosis. Ka-Mi-Chung-Gan-Tang (KMCGT) is a decoction used for fatty liver as oriental medicines in China. The prescription is composed of Ginseng Radix, Bupleuri Radix, Scutellariae Radix, Pinelliae Tuber, Artemisiae capillaris Herba, Gardeniae Fructus, Zingiberis Rhizoma, Zizyphi Fructus and Glycyrrhizae Radix etc. We have induced alcoholic fatty liver by ethanol administration (6 g/kg, single dose/day, for a week) on rats and observed changes of triglyceride, cholesterol and lipid peroxidation in liver tissues of them. Also we checked the activities of GOT and GPT in blood of rats. KMCGT inhibited significantly the increase of triglyceride, cholesterol, lipid peroxidation level and effectively the increase of malondialdehyde (MDA).

• Korean Journal of Pharmacognosy
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• v.31 no.4
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• pp.383-389
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• 2000

GRF (Korean Red Ginseng mixed formula) consists of six herbs such as Ginseng Radix rubra Koreana, Lycii Fructus, Artemisiae Capillaris Herba, Poria, and Glycyrrhizae Radix and Hoveniae Fructus. For the evaluation of hepatoprotective effect of GRF, the study was performed on protective effect against hepatic damage induced by galactosamine in vitro and ccl4 in vivo and also elucidate antioxidant activity. In vitro assay with 1.1 mM galactosamine, protection (%) was 44% (GR), and 58% (GRF-A) at 50 ug/ml. GRF effectively protected fatty degenertion and necrosis in murine hepatic damage induced by ccl4. For the -antioxidant study, GRF inhibited hemolysis of erythrocyte and decolored DPPH (2,2-diphenyl-l-picrylhydrazyl) free radical in a dose dependent manner more effetively than GR alone in vitro. GRF and GR significantly suppressed the time course $(1\;hr{\sim}6\;hr)-level$ of MDA (malondialdehyde) following AAPH (2,2'-azo-bis-(2-amidino -propane) dihydrochloride) treatment in vivo as compared with control data. From the results it can be concluded GR and GRF exerted the hepatoprotective effect by dint of antioxidant activity.

• Korean Journal of Pharmacognosy
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• v.32 no.3 s.126
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• pp.212-218
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• 2001

The water extracts of 82 Korean medicinal herbs were prepared and were examined for the binding affinity on the glycine binding site of NMDA (N-methyl-D-aspartate) receptor prepared by the synaptic membranes from the forebrains of male Sprague-Dawley rats. Among the tested, the extracts of Dioscoreae Rhizoma, Hoveniae Semen cum Fructus, Astragali Radix, Armeniacae Semen, Huttuynia cordata Herba, Acanthopanacis Cortex, Aurantii nobilis Pericarpium, Phellinus linteus, Amomi Fructus, Artemisiae capillaris Herba, Polyporus, Agastachis Herba and of Galli Stomachichum Corium were found to exhibit significant competitions with $[^3H]-MDL$ 105,519 for the glycine specific binding site of NMDA receptor in a dose dependent manner, respectively.