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Study of overlapping setting up of Planning Target Volume for Improving Target Coverage adjacent Organ At Risk (손상위험장기에 인접한 표적 Coverage 개선을 위한 Planning Target Volume 중복 설정에 관한 연구)

  • Lee, Jung Woong;Kim, Bo Kyum;Mun, Jun Ki;Woo, Hun;Lee, Yang Hoon;Jeon, Chang Woo;Lee, Jea Hee
    • The Journal of Korean Society for Radiation Therapy
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    • v.31 no.2
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    • pp.33-41
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    • 2019
  • Purpose: The purpose of this study is to improve the reduction of coverage of PTVs adjacent to organ at risk (OAR) by setting up overlapping Planning Target Volume (PTV) during Volumetric Modulated Arc Therapy(VMAT). Materials and Methods: In patients who received Whole Brain, Gall Bladder and Rectum radiation therapy, We compared the cover change, maximum dose, Homogenicity Index and Conformity Index of PTV and also compared the maximum dose and average dose change of Organ At Risk by organizing treatment plans that are not applied overlaped PTV and treatment plans that are applied overlaped PTV in areas where coverage is insufficient. Results: overage of treatment plans with overlapping PTVs was increased in all patients, and overall coverage was also increased in each of the four patients. The maximum dose for PTV was increased in five patients, and the Homogenicity Index and Conformity Index for all patients did not differ much. The maximum dose of the lens was increased by 1.12 times, and the maximum dose was decreased in two patients for brain stem. The mean dose of the eyeball was increased by a maximum of 1.15 times, and there was no significant difference between both parotid gland. In case of gallbladder cancer patients, the mean dose in the liver and colon was decreased, and the mean dose in the duodenum was increased. In the case of rectal cancer patients, the mean dose was reduced for both femur and bladder set as OARs. The overall MU was shown to be similar in four patients, excluding one. Conclusion: If the critical dose of OAR is considered and used properly, I think it is a useful way to improve coverage of PTV.

Early Life History and Spawning Behavior of Chinese Minnow, Rhynchocypris oxycephalus Reared in the Laboratory (실험실에서 사육한 버들치의 산란습성(産卵習性) 및 초기생활사(初期生活史))

  • Han, Kyeong-Ho;Noh, Byeong-Yul;O, Sung-Hyun;Park, Joon-Taek;Cho, Jae-Kwon;Seong, Ki-Baik
    • Korean Journal of Ichthyology
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    • v.11 no.2
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    • pp.177-183
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    • 1999
  • This study was conducted to observe the spawning behavior and early life history of chinese minnow, Rhynchocypris oxycephalus reared in the laboratory. The spawning period of Rhynchocypris oxycephalus is from May to June in nature. The eggs of Rhynchocypris oxycephalus were spawned on the sand and surface of the gravel. The fertilization eggs were demersal in shape and adhesive, released as a clump forming a thin layer and their diameter were 1.70~1.90mm (mean 1.80 mm, n=20). Hatching of eggs was started in 88 hour 45 minute after fertilization at water temperature $19{\pm}0.5^{\circ}C$ and finished in 90 hour. Newly-hatched larvae were measured 4.87~5.02 mm in total length (TL, mean 4.94 mm), mouth and anus were not opened. 6 days old larvae were 6.32~6.56 mm in TL (mean 6.44 mm). Yolk sac was almost absorbed, mouth and anus was began to open. 13 days old larvae were 6.74~6.91 mm in TL (mean 6.82 mm). Part of Dorsal fin was began to rising and myomere number was 15+23=38. 25 days after hatching, total length of larvae was 8.45~8.60 mm (mean 8.52 mm). Dorsal and anal fin rays became differentiated, and also caudal part of the notocord flexion was achieved at $45^{\circ}C$. In the time, growth rate was higher than the other stage. Aggregate numbers of all fin rays were completed at 16.39~16.57 mm in TL (60 days after hatching), at which time the larvae reached the juvenile stage, but fin-fold on ventral was remained yet. External features of adult specimens were almost completed at 80 day old juveniles (18.69~18.87 mm in TL).

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Thermal Conductivity and Pore Characteristics of Low-Temperature Sintered Lightweight Aggregates Mode from Waste Glass and Bottom Ash (바텀애쉬와 폐유리를 사용하여 제조한 저온소성 경량골재의 열전도율과 기공특성)

  • Lee, Han-Baek;Ji, Suk-Won;Seo, Chee-Ho
    • Journal of the Korea Concrete Institute
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    • v.22 no.6
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    • pp.851-858
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    • 2010
  • In this study, waste glass and bottom ash were used as basic materials in order to secure a recycling technology of by-products which was mostly discarded and reclaimed. In addition, because softening point of waste glass is less than $700^{\circ}C$ and bottom ash includes combustible material, it was possible to manufacture low-temperature sintering lightweight aggregates for energy saving at $800{\sim}900^{\circ}C$ that it is as much as 20~30% lower than sintering temperature of existing lightweight aggregates. Thermal conductivity of newly-developed lightweight aggregates was 0.056~0.105W/m. K and its porosity was 40.36~84.89%. A coefficient of correlation between thermal conductivity and porosity was -0.97, it showed very high negative correlationship. With this, we were able to verify that porosity is key factor to affect thermal conductivity. Microstructure of lightweight aggregates by $CaCO_3$ content and replacement ratio of bottom ash in the variation of temperature were that $CaCO_3$ content increased along with pore size while replacement ratio of bottom ash increased as pore size decreased. Specially, most pores were open pore instead of closed pore of globular shape when replacement ratio of bottom ash was 30%, and pore size was small about 1/10~1/5 as compared with case in bottom ash 0~20%. In addition, open pore shapes were remarkably more irregular form of open pore in $900^{\circ}C$ than $700^{\circ}C$ or $800^{\circ}C$ when replacement ratio of bottom ash was 30%. We reasoned hereby that these results will influence on absorption increase, strength and thermal conductivity decrease of lightweight aggregates.

Effect of Autoclave and Microwave Treatments on Quality of Bread (반죽에 가압가열 및 Microwave 처리가 빵의 품질에 미치는 영향)

  • Kim, Koth-Bong-Woo-Ri;Choi, Jung-Su;Kim, Dong-Hyun;SunWoo, Chan;Jung, Seul-A;Kim, Hyun-Jee;Jeong, Da-Hyun;Jeong, Hee-Ye;Choi, Ho-Duk;Ahn, Dong-Hyun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.41 no.5
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    • pp.681-686
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    • 2012
  • This study conducted autoclave and microwave treatments on dough to determine if there were any changes in quality after the dough was cooked into bread. Wheat dough after secondary fermentation was treated with a microwave (1 min), an autoclave (30 min), and both an autoclave and microwave (30 min/1 min). We then measured the pH, moisture content, color, texture, and sensory evaluation. The results showed that pH was slightly decreased when it was treated in an autoclave (baking and no baking) and autoclave/microwave (baking and no baking). When microwaved and baked, the moisture content most decreased compared to the control. In crust color, there were no considerable differences in lightness, redness, or yellowness compared to the control, except when microwaved (no baking). The lightness of the crumb color decreased, while redness and yellowness increased, when dough was treated with an autoclave (baking and no baking) and autoclave/microwave (baking and no baking). Hardness, gumminess, chewiness and shear force were significantly increased when dough was treated with an autoclave (baking and no baking) and autoclave/microwave (baking and no baking) compared to the control. In the sensory evaluation, there were no considerable differences in color, aroma, taste, or overall preference when microwaved and baked. Color, aroma, shape, and overall preference were the worst when the dough was treated with autoclave/microwave (baking and no baking). These results suggest that autoclaving and microwaving may reduce the quality of bread, and countermeasures to this problem are necessary.

ANALYSIS OF ER:YAG LASER IRRADIATION ON CUTTING EFFICACY AND TEMPERATURE CHANGES OF DENTIN (Er:YAG 레이저의 상아질 삭제효과 및 이에 따른 온도변화)

  • Im, Kwang-Ho;Lee, Chang-Seop;Lee, Sang-Ho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.28 no.1
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    • pp.32-44
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    • 2001
  • The purpose of this study was to investigate the effects of Er : YAG laser on cutting efficacy and temperature changes of dentin. We used the dentin specimens of human premolars and molars which contain the physiologic saline and maintain the pulpal pressure in dentinal tubules. Each specimen was exposed to Er : YAG laser with non-contact handpiece type delivery system under different treatment condition of irradiation energy, pulse repetition rate, and exposure time. Two procedures were conducted by the presence of water flow during lasing. The specimens were grouped by thickness of dentin. We investigated the cavity pattern, volume, and temperature change of dentin specimen to determine the cutting efficacy and temperature rise of Er : YAG laser, and obtained following results. 1. Cutting volume of dentin was increased by increasing the irradiation energy, pulse repetition rate, and exposure time(P<0.05). 2. Margins of abulated cavities were sharp and clean and floors of cavities were conical in shape and showing smooth surfaces. Upper diameter of abulated cavities were increasing as laser parameter of irradiation energy, pulse repetition rate, and exposure time were increased. A few cracks were observed on abulated surfaces under treatment condition of laser parameter with 150mJ, 5Hz, and 5sec. 3. Temperature was increased as laser parameter of irradiation energy, pulse repetition rate, and exposure time were increased, and temperature rise was decreased as dentin thickness was increased(P<0.05). 4. Temperature rise was decreased under water flow compared with no water flow during laser exposure(P<0.05). From these results, we think that the method of using a Er:YAG laser would be effective and safe in cutting dentin for clinical application.

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A Survey on Intake of Protein Supplement of University Students Majoring in Physical Education (체육교육전공 대학생들의 단백질 보충제 섭취실태)

  • Lee, Jooeun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.10
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    • pp.1607-1613
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    • 2014
  • The purpose of this study was to investigate intake of protein supplements by university students majoring in physical education. Intake experience rate, reasons for intake, purchasing place, effectiveness, satisfaction level, and side effects were analyzed using a questionnaire. Of 476 students, those who consumed protein supplements were 198 (41.6%). Male's intake experience rate was significantly higher than that of females, and members of health-related clubs also consumed more protein than non-members. The main purchasing place was internet shopping malls, and users obtained information from their friends or upperclassmen. The most frequently consumed protein supplement was 'WPH', and the most frequent reason for intake was 'building muscle or maintaining body shape'. For effectiveness, 'normal' was 49.0% and 'effectiveness' was 33.3%. For satisfaction, 'satisfaction' was 45.5% and 'normal' was 43.4%. The rate of side effects was 44.9%, and digestive issues such as diarrhea and indigestion were observed with high frequency. The results of this study show that education is needed for nutritional knowledge, adequate intake, and side effects of protein supplements.

A Hydrodynamic Modeling Study to Analyze the Water Plume and Mixing Pattern of the Lake Euiam (의암호 수체 흐름과 혼합 패턴에 관한 모델 연구)

  • Park, Seongwon;Lee, Hye Won;Lee, Yong Seok;Park, Seok Soon
    • Korean Journal of Ecology and Environment
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    • v.46 no.4
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    • pp.488-498
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    • 2013
  • A three-dimensional hydrodynamic model was applied to the Lake Euiam. The lake has three inflows, of which Gongji Stream has the smallest flow rate and poorest water. The dam-storage volume, watershed area, lake shape and discharge type of the Chuncheon Dam and the Soyang Dam are different. Therefore, it is difficult to analyze the water plume and mixing pattern due to the difference of the two dams regarding the amount of outflow and water temperature. In this study, we analyzed the effects of different characteristics on temperature and conductivity using the model appropriate for the Lake Euiam. We selected an integrated system supporting 3-D time varying modeling (GEMSS) to represent large temporal and spatial variations in hydrodynamics and transport of the Lake Euiam. The model represents the water temperature and hydrodynamics in the lake reasonably well. We examined residence time and spreading patterns of the incoming flows in the lake based on the results of the validated model. The results of the water temperature and conductivity distribution indicated that characteristics of upstream dams greatly influence Lake Euiam. In this study, the three-dimensional time variable water quality model successfully simulated the temporal and spatial variations of the hydrodynamics in the Lake Euiam. The model may be used for efficient water quality management.

Aortic and Mitral Valve Replacement with Reconstruction of the Intervalvular Fibrous Skeleton in Prosthetic Valve Endocarditis (인공판막 심내막염에서 판막간 섬유체 재건을 이용한 대동맥판 및 승모판 치환술)

  • Baek, Man-Jong;Kim, Wook-Sung;Oh, Sam-Se;Jeon, Yang-Bin;Ryu, Jae-Wook;Kong, Joon-Hyuk;Lim, Cheong;Kim, Soo-Cheol;Kim, Woong-Han;Na, Chan-Young;Lee, Seong-Ki;Lee, Chang-Ha;Lee, Young-Tak;Yoon, Youg-Woong;Park, Young-Kwang;Kim, Chong-Whan
    • Journal of Chest Surgery
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    • v.34 no.7
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    • pp.561-565
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    • 2001
  • Patients who have complex endocarditis with involvement of both the aortic and mitral valves and intervalvular fibrous skeleton are among the most difficult to treat and still have the highest surgical mortality and morbidity rates. We report one case of aortic and mitral valve replacement with reconstruction of the fibrous skeleton performed in a 55-year-old female patient who had an aortic annular abscess and both the aortic and mitral prosthetic valve endocarditis with destruction of the fibrous skeleton. Previously, she had undergone redo double valve replacement\`, Transesophageal echocardiogram showed the paravalvular defect at the noncoronary aortic sinus and abnormal sinus tract along the fibrous skeleton. Emergent operation was performed due to positive blood cultures of staphylococcus epidermidis and persistent sepsis despite appropriate antibiotic therapy. After aortotomy extended to the roof of left atrium, both prosthetic valves and destroyed fibrous skeleton were completely resected and the aortic annular abscess was debrided and closed with a bovine pericardial patch. Reconstructions of both aortic and mitral annuli and the fibrous skeleton were done by using two separate bovine pericardial patches in triangular shape and mechanical valves were implanted. Postoperatively, adequate antibiotic therapies were continued and the patient was discharged at the postoperative 72 days without evidence of recurrence of endocarditis. Transthoracic echocardiogram of the postoperative 8 months shows no paravalvular leakage or recurrence of endocarditis and the patient has been followed up with no symptom.

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Characterization of Mineralogical Changes of Chrysotile and its Thermal Decomposition by Heat Treatment (열처리에 따른 백석면의 광물학적 특성 변화와 열분해 과정 연구)

  • Jeong, Hyeonyi;Moon, Wonjin;Roh, Yul
    • Economic and Environmental Geology
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    • v.49 no.2
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    • pp.77-88
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    • 2016
  • Chrysotile is a 1:1 sheet silicate mineral belonging to serpentine group. It has been highlighted studies because of uses, shapes and structural characteristics of the fibrous chrysotile. However, it was designated as Class 1 carcinogen, so high attentions were being placed on detoxification studies of chrysotile. The objectives of this study were to investigate changes of mineralogical characteristics of chrysotile and to suggest detoxification mechanism of chrysotile by thermal decomposition. Samples for this study were obtained from LAB Chrysotile mine in Canada. The samples were heated in air in the range of 600 to $1,300^{\circ}C$. Changes of mineralogical characteristics such as crystal structure, shape, and chemical composition of the chrysotile fibers were examined by TG-DTA, XRD, FT-IR, TEM-EDS and SEM-EDS analyses. As a result of thermal decomposition, the fibrous chrysotile having hollow tube structure was dehydroxylated at $600-650^{\circ}C$ and transformed to disordered chrysotile by removal of OH at the octahedral sheet (MgOH) (Dehydroxylation 1). Upon increasing temperature, it was transformed to forsterite ($Mg_2SiO_4$) at $820^{\circ}C$ by rearrangement of Mg, Si and O (Dehydroxylation 2). In addition, crystal structure of forsterite had begun to transform at $800^{\circ}C$, and gradually grown 3-dimensionally to enstatite ($MgSiO_3$) by recrystallization after the heating above $1,100^{\circ}C$. And then finally transformed to spherical minerals. This study showed chrysotile structure was collapsed about $600-700^{\circ}C$ by dehydroxylation. And then the fibrous chrysotile was transformed to forsterite and enstatite, as non-hazardous minerals. Therefore, this study indicates heat treatment can be used to detoxification of chrysotile.

Effects of Dense Planting on the Growth and Producivity in Hot Pepper(Capsicum annum L.) (재식밀도(裁植密度)가 고추의 생육(生育) 및 생산성(生産性)에 미치는 영향(影響))

  • Kim, Kwang-Yong;Park, Sang-Keun;Lim, Sang-Cheol
    • Korean Journal of Environmental Agriculture
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    • v.2 no.1
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    • pp.45-54
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    • 1983
  • This experiment was carried out to investigate effects of dense planting on the growth and productivity in varieties of hot pepper at open field. Three varieties (Joseng jinheung, Weonkyo No. 304 and Bulam house Putgochu) were sowed on Jan. 30th and transplanted on May 12th. The planting densities used were 3,300, 5,500 and 8,300 plants per 10a. The results obtained are as follows: 1) With higher plant density, the plant shape was changed from open-type to upright-type and the yield was increased, presumably due to the increase of leaf area index. 2) LAI and SLA per unit area were increased by denser planting. Wonkyo No. 304 presented the highest LAI and the lowest SLA. 3) Dry matter weight per unit area was also increased, however the LW/SW ratio was tended to decrease on denser planting. 4) Through crop growth analysis, it was determined that CGR and NAR were increased during the early growth stages and became decreased from last June. 5) Light intensity under the canopy formed by denser planting was decreased by 40% measured at 60 ㎝ above the soil surface. The vertical distribution of fruits became concentrated the upper part of plant. Fruit yield per unit area in denser planting was increased as compared to the conventional planting. The number of fruit setting decreased. 6) Generally, no differences in yield were detected in comparison between denser planting and conventional planting harvested on Aug. 30th and Oct. 15th, respectively. But Weonkyo No. 304 increased yield by 18% in denser planting.

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