• Title/Summary/Keyword: A-contraction

Search Result 2,586, Processing Time 0.045 seconds

A Comparison of the Responses of Lower Vertebrate Intestines to Prostaglandin $E_1\;and\;E_2$

  • Hong Ki-Whan
    • The Korean Journal of Pharmacology
    • /
    • v.11 no.1 s.17
    • /
    • pp.27-31
    • /
    • 1975
  • 1. The isolated strips of guinea-pig, fowl and reptiles (snake and tortoise) showed consistenly excitatory responses to $PGE_1\;and\;E_2$, which were dose-dependent. 2. Frog intestine revealed inhibitory responses to both $PGE_1\;and\;PGE_2$ except a small of $PGE_2$ (1-10 ng/ml) caused slight contraction. 3. The intestines of pieces showed inconsistent responses to $PGE_1\;and\;E_2$. In fresh-water fish(carp), $PGE_1$ produced relaxation under the dose of 50 ng/ml, and contraction by the large doses, but $PGE_2$ consistently caused contraction in dose-dependent manner. However, the strips of sea-water fish revealed the different responses to PGE compound: $PGE_1$ caused relaxation and $PGE_2$ conversly contraction even though in small degree. 4. These results that there are genera differences in the responses of the longitudinal strips of intestine to $PGE_1\;and\;PGE_2$ was assumed to be possibly correlated with evolutionally primitive function of gut.

  • PDF

Inhibition of C2-ceramide induced contraction in cat esophageal smooth muscle cell by newly synthesized Ceramide analogues

  • Lee, Doo-Won;Yang, Sung-Jun;Lee, Yul-Pyo;Lee, Tai-Sang;Park, Jun-Hong;Choi, Su-Hang;Yim, Chul-Bu;Sohn, Uy-Dong;Choi, Tae-Sik
    • Proceedings of the PSK Conference
    • /
    • 2002.10a
    • /
    • pp.248.1-248.1
    • /
    • 2002
  • It has been shown that C2-ceramide (C2), short chain ceramide, plays a role in mediating contraction of cat esophageal smooth muscle cells. We examined the effect of newly synthesized ceramide analogues on the C2-ceramide induced contraction in esophageal smooth muscle cells isolated with collagenase. C2-ceramide produced contraction of smooth muscle cells in a dose dependent manner. (omitted)

  • PDF

Easing Contraction for Three-dimensional construction of Sleeve (소매입체구성을 위한 오그림)

  • Lee, Myung-Hee
    • Journal of the Korean Society of Costume
    • /
    • v.42
    • /
    • pp.223-230
    • /
    • 1999
  • Dressmaking which is defined as the process of changing two-dimensional cloth into three-dime-nsional clothes needs a lot of joining parts. Particularly sleeve needs a more curved surface than other joining parts owing to shape of the top of arms. Easing is used to control the fullness along the seam-line to create the fullness curved shape of the sleeves and it plays an important role in increasing three-dimensional constru-ction power. unfortunately sufficient data regarding effective easing conditions to increase three-dimensional construction power of sleeve are not available. Therefore the author tried to investigate the effective easing conditions to increase three-dimensional construction power of sleeve by cap height. Easing construction power of sleeve by cap height. Easing contraction made by different angles on the sleeve cap curve line previous work were examined and the effective easing conditions according to the variation of angles were determined. This study contains the following objectives. Firstly to obtain the easing contraction ratio in sleeve according to the above easing conditions. Secondly to investigate the three-dimensional construction power or sleeve by the factors of easing contraction. Thirdly to determine for each sleeve the effective easing conditions on the basis of the calcuative easing contraction ratio in the sleeve patterns by cap heights.

  • PDF

An Analysis of Multichannel EMG in Continuous Isometric Contraction of Human Muscle (근육의 지속적인 등척성 수축시의 다 채널 근전도 해석)

  • Lee, Seung-Ju;Kim, Ki-Young;Yoon, Chae-Hyun;Lee, Hyun-Chul;Yoon, Yang-Woung;Park, Hyung-Jun
    • Proceedings of the KIEE Conference
    • /
    • 2002.07d
    • /
    • pp.2696-2698
    • /
    • 2002
  • In this study, the comparison of the contractile states change at prime mover muscle with that at synergist muscle was executed, while the muscle contracted continuously with isometric contraction. The contractile states of muscle becomes to change when the voluntary contraction of skeletal muscle is progressed continuously. Such the contractile states change is divided into three states in consideration for not only physiological change but also the psychological change by CNS(central nervous system) as "stable state", "fatigue state" and "pain state". As a result of this study, the prime mover muscle is reached "pain state" but the synergist muscle is not reached. Namely the synergist muscle is delayed state than the prime mover muscle. This result judged that although the prime mover muscle have reached a limit when contraction is continued, owing to effect of delayed state of the synergist muscle, the prime mover muscle is endured some more contraction.

  • PDF

Evaluation of Upper-Limb Motor Recovery after Brain Injury: The Clinical Assessment and Electromyographic Analysis (뇌손상 후 상지 운동기능 회복 평가: 임상적 평가 및 운동반응 근전도 분석)

  • Kim, Young-Ho;Tae, Ki-Sik;Song, Sung-Jae
    • Physical Therapy Korea
    • /
    • v.12 no.1
    • /
    • pp.91-99
    • /
    • 2005
  • We assessed whether the use of a symmetrical upper limb motion trainer in daily repetitive training for a 6-week period reduced spasticity and improved motor function in three chronic hemiparetic patients. Upper limb motor impairment and disability were measured by the Fugl-Meyer Assessment (FMA), Modified Ashworth Scale (MAS) and Manual Muscle Test (MMT), respectively. The electromyography (EMG) of the affected hand was recorded during isometric wrist flexion and extension. In all patients, FMA and MMT scores were significantly improved after the 6-week training. However, MAS scores of the affected wrist spasticity did not change considerably. Onset and Offset delays in muscle contraction significantly decreased in the affected wrist. The co-contraction ratio of flexor and extensor muscles significantly increased after the 6-week training. Onset and offset delays of the muscle contraction and co-contraction ratio correlated significantly with the patients' FMA. This study showed that repetitive, symmetric movement training can improve upper limb motor functions and abilities in chronic hemiparetic patients. Also, the EMG assessment of motor response is likely to provide insights into mechanisms and treatment strategies for motor recovery in chronic hemiparetic patients.

  • PDF

A Study on the Variation of the Body surface Area by the Arm movements to Somatotype -The Subject of the College Men- (체형별 상복동작에 따른 상체의 체표면 변화에 관한 연구 -남자대학생을 중심으로-)

  • 김진경
    • Journal of the Korean Home Economics Association
    • /
    • v.26 no.2
    • /
    • pp.1-13
    • /
    • 1988
  • The purpose of this study was to classify somatotype of males, to show changes of the body skin surface by the somatotype. The size of sample was 156 males between age 20 and 24. Somatotype classified into Bending somatotype, Standard somatotype, Turning over somatotype. And according to the somatotype, changing of the upper part of the body by the arm movements analyzed through gypsum experiment. The result obtained from this study were as follows; 1. the variation of the upper part of the body form by changing the am movements, by the increasing of movements, shoulder-point ws moved to be inside or upside, the anterior armpit point & armpit point were moved to the upside. 2. As a result of investigating into the rate of the expansion and contraction of the basic lines and body surface area by the arm movements, the rate of expansion and contraction of the basic lines by the arm movements, the side sea length showed the maximum rate of extension in 135 degrees, the shoulder length showed the maximum rate of contraction in 135 degrees. The rate of expansion and contraction on the body surface area by the arm movements showed the phenomenon of contraction, of items F1, F6, B1, B9 showed the phenomenon of extension, of items F3, F4, F8, F9, B8, B9. 3. According to somatotypes, items which show the significant difference were, of items f3, f8, b3, b8, F2, F7, F8, B3, B7, in all movements.

  • PDF

Effect on Squatting with Short Foot Exercise on Muscle Activation and Onset of Contraction in the Quadriceps Femoris

  • Noh, Hyunwoo;Jung, Jihye;Lee, Seungwon
    • Physical Therapy Rehabilitation Science
    • /
    • v.10 no.3
    • /
    • pp.367-373
    • /
    • 2021
  • Objective: Short foot exercise(SFE) is frequently used to increase the medial longitudinal arch of the foot, as well as the intrinsic foot muscles. This studyinvestigated the effects of SFE onmuscular activity and the onset of contraction of the quadriceps femoris muscle during squats in healthypeople. It also aimed to compare and analyze the results with those of the general squat method and propose a more efficient squat method. Design: Cross-sectional study. Methods: This study compared 20 adults (male=10, female=10) who statisfied the inclusion criteria for the muscle activity and onset of the muscle contraction of the quadriceps femoris using surface EMG under two conditions: general squats and SFE squats. Results: Separate analyses and comparisons of the outcomes of the SFE squat and the general squat, showed a significant increase in the muscle activities of the rectus femoris and vastus medial muscles in both males and females (p<0.05). The onset of muscle contraction was significantly delayed for the vastus lateralis relative to that for the vastus medialis (p<0.05). However, it delayed significantly in females, but not in males. Conclusions: The SFE squats induced selective muscular activities of the rectus femoris and vastus medialis muscels and affected the onset of contraction of the vastus medialis and lateralis muscles.

Rotational Stability of AcrySof Toric Intraocular Lens Over Time: Influence of Capsulorhexis Contraction

  • Kim, Joong Hee;Cho, Kyong Jin
    • Medical Lasers
    • /
    • v.9 no.1
    • /
    • pp.44-50
    • /
    • 2020
  • Background and Objectives To evaluate the rotational stability of AcrySof toric intraocular lenses (IOL) by considering lapse of postoperative time and influence of capsulorhexis contraction. Materials and Methods A prospective, masked, single center study was conducted on 19 patients who had undergone microcoaxial cataract surgery and AcrySof toric IOL implantation. Slit-lamp retroillumination photographs of anterior segments were obtained from all patients after 1 week, 1 month and 3 months post-surgery. The degree of alteration of the postoperative IOL axis alignment and the amount of anterior capsular shrinkage were analyzed using Adobe Photoshop software. Results The mean degree of toric IOL axis misalignment was 2.18 (±20.2) degrees at 3 months follow-up. Quadrant analysis of the capsulorhexis aperture area at 1 week and 1 month post-operative, showed counterclockwise IOL rotation when the capsule contraction was dominant in the haptic part as well as clockwise rotation when dominant in the non-haptic part (p = 0.015). Conclusion The direction and degree of AcrySof toric IOL rotation differed throughout the follow-up period. Since most misalignments were found on the first post-operative day, physicians should try to minimize peri-operative risk factors that influence IOL rotation. There was also a correlation between the part of anterior capsule contraction and the direction of IOL rotation.

Experimental Studies on the Effects of Chunggeumtang (청금탕(淸金湯)의 효능(效能)에 관(關)한 실험적(實驗的) 연구(硏究))

  • Kim, Eung-Sik;Lee, Si-Hyeong
    • The Journal of Internal Korean Medicine
    • /
    • v.18 no.2
    • /
    • pp.1-26
    • /
    • 1997
  • Chunggeumtang has been used in Korea for many centuries as a treatment for respiratory disease. The effect of Chunggeumtang on tracheal smooth muscle is not konwn. The purpose of the present study is to determine the effect of Chunggeumtang on histamine and acetylcholine induced tracheal smooth muscle contraction in rats and guinea pigs. Guinea pig(500g, male) and Sprague Dawley rats (250g, male) were killed by $CO_2$ exposure and a segment (8-10mm) of the thoracic trachea from each rat and guinea pig was cut into equal swegments and mounted 'in pairs' in a tissue bath. Contractile force was measured with force diplacement transducers under 0.5g loading tension. The dose of histamine (His) and acetylcholine (Ach) which evoked 50% of maximal response ($ED_{50}$) was obtained from cumulative dose response curves for histamine and acetylcholine($10^{-7}{\sim}10^{-4}M$). Contractions evoked by His ($ED_{50}$) and Ach ($ED_{50}$) were inhibited significantly by Chunggeumtang. In guinea pig tracheal smooth muscle, the mean percent inhibition of acetylcholine induced contraction was $6.1%after\;30{\mu}l/ml$ Chunggeumtang, and 49.4% (p<0.01) after $100{\mu}l/ml$ Chunggeumtang. In rat tracheal smooth muscle, the mean percent inhibition of acetylcholine induced contraction was $6.7%\;after\;30{\mu}l/ml$ Chunggeumtang, and $54.2%\;(p<0.01)\;after\;100{\mu}l/ml$ Chunggeumtang. Also, in guinea pig tracheal smooth muscle, the mean percent inhibition of histamine induced contraction was $30.6%\;(p<0.05)\;after\;30{\mu}l/ml$ Chunggeumtang, and $53.0%\;(p<0.01)\;after\;100{\mu}l/ml$ Chunggeumtang. In rat tracheal smooth muscle, the mean percent inhibition of histamine induced contraction was $24.1%\;(p<0.05)\;after\;30{\mu}l/ml$ Chunggeumtang, and $55.3%\;(p<0.01)\;after\;100{\mu}l/ml$ Chunggeumtang. Propranolol and indomethacin($10^{-7}M$) slightly but significantly attenuated the inhibitory effects of Chunggeumtang. Following treatment with propranolol, the mean percent inhibition caused by $100{\mu}l/ml$ Chunggeumtang fell to 27.6% in guinea pig induced by acetylcholine contraction and by $100{\mu}l/ml$ Chunggeumtang fell to 28.7% (p<0.05) in rat induced by acetylcholine contraction and the mean percent inhibition caused by $100{\mu}l/ml$ Chunggeumtang fell to 16.2% in guinea pig induced by histamine contraction and by $100{\mu}l/ml$ Chunggeumtang fell to 28.7% (p<0.05) in rat induced by histamine contraction. Indomethacin, the mean percent inhibition caused by $100{\mu}l/ml$ Chunggeumtang fell to 20.0% in guinea pig induced by acetylcholine contraction and by $100{\mu}l/ml$ Chunggeumtang fell to 16.9% (p<0.05) in rat induced by acetylcholine contraction and the mean percent inhibition caused by $100{\mu}l/ml$ Chunggeumtang fell to 16.4% in guinea pig induced by histamine contraction and by $100{\mu}l/ml$ Chunggeumtang fell to 23.1% (p<0.05) in rat induced by histamine contraction. Methylene blue($10^{-7}M$) did not significantly alter the inhibitory effect of Chunggeumtang. Also, I could find the effects of Chunggeumtang and Chunggeumtanggamorphine on the tracheal smooth muscle in guinea pig and rat did not change significantly. These results indicate that Chunggeumtang can relax histamine and acetylcholine-induced contraction of guinea pig and rat tracheal smooth muscle, and that this inhibition involves sympathetic effects and the release of cyclooxygenase products.

  • PDF

Effects of a Full Body Massage on Uterine Contraction, Length of Labor, Type of Delivery, and Drug Intervention for Primipara during Labor (분만 중 전신마사지가 초산부의 자궁수축, 분만소요시간, 분만형태 및 약물사용에 미치는 효과)

  • Lee, Kun-Ja;Chang, Chun-Ja;Jo, Hyun-Sook;Kim, Mi-Ran
    • Women's Health Nursing
    • /
    • v.8 no.4
    • /
    • pp.538-549
    • /
    • 2002
  • This study was designed to test the effects of a full body massage on uterine contraction, length of labor, type of delivery, and drug intervention for primipara during labor. Data were collected using a quasi-experiment method (nonequivalent control group, pre-post test design) from November 1, 2001 to July 31, 2002. The subjects of this experiment consisted of 28 women in the experimental group and 29 in the control group, out of 57 primipara hospitalized at the U OB & GYN hospital in Inchon. The experimental group was given a 20 minute full body massage for each of the three delivery phases (latent, active, and transition). The control group was given conventional delivery care. Three (3) parameters were analyzed in this experiment. (1) The interval, duration, and strength of uterine contraction, using an electric tocodynamometer (2) The elapsed time for stage 1 and stage 2 labor. (3) The types of deliveries and drug interventions, using postpartum medical records The data collected were analyzed using the repeated measures analysis of variance (ANOVA), t-test, and $x^2$ test of the SPSS program. The results of the experiment are as follows: 1) Uterine contraction interval was significantly reduced (F=3.210, p=.050). Duration of uterine contraction showed significant increase only during the transition phase (t=-2.319, p=.023). Strength of uterine contraction showed no significant difference. 2) Total length of labor was significantly shortened (t=-5.245, p=.000). The length of 1st stage labor was significantly shortened (t=-5.164, p=.000), with latent phase showing (t=-4.709, p=.000), active phase (t=-2.973, p=.005), and transition phase (t=-2.031, p=.047). The length of 2nd stage labor showed no significant difference. 3) The number of natural deliveries were significantly increased ($x^2$=13.127, p=.004). 4) The number of drug interventions were significantly fewer ($x^2$= 4.493, p=.034). In conclusion, this study shows that a full body massage has a significantly positive effect on uterine contraction interval, length of labor, type of delivery, and drug intervention. Therefore, this study suggests that a full body massage be used clinically to help primipara during labor.

  • PDF