• Design & Manufacturing
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• v.6 no.2
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• pp.74-78
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• 2012

A multi-cavity injection mold system of protein chip for point-of-care with cavity temperature and pressure sensors was proposed in this work. In advance of manufacturing for the multi-cavity injection mold system, a single cavity injection mold system to mold protein chip was considered. Injection molding analysis for the presented system was performed to optimize the process of the molding and suggest guides to design. On the basis of the results for the single cavity system, a multi-cavity injection mold system for protein chip was analyzed, designed and manufactured with cavity temperature and pressure sensors. Results of balanced filling for protein chip models were obtained from the presented mold system.

• Journal of Navigation and Port Research
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• v.44 no.2
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• pp.73-78
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• 2020

The cruise industry in the Mediterranean region increased from 2000-2018, being the second most important region after the Caribbean. The purpose of this study was to analyze the networks and hub ports of the Mediterranean. This paper used the SNA (Social Network Analysis) methodology, which includes Hub and Authority Combined Centrality (HACC) that has been used to analyze cruise port centrality, as well as degree centrality such as In-Degree, Out-Degree, and Betweenness. This empirical study suggests that the top three ports of the Mediterranean ports' network in terms of hub index are Barcelona, Civitavecchia, and Palma de Mallorca. The academic implications are the suggestion for data integration based on real itineraries and numbers of POC (Port of Calls), as well as the selection of the hubs of the targeted areas. The practical implications are suggested such as a clear requirement for cruise industry, as a way to widen the scope for the Mediterranean region and a valuable reference for cruise ship companies to select the best fit home ports.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.2341-2344
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• 2014

Background: p53 protein expression has been detected immunohistochemically in papillary thyroid carcinoma(PTC). We investigated the relations between its expression and clinicopathologic features and its significance as a diagnostic marker. Materials and Methods: We compared and evaluated 93 patients in whom thyroidectomy with lymph node dissection had been performed to treat PTC for clinicopathologic significance and 102 patients with 23 papillary thyroid overt carcinomas (POC), 57 papillary thyroid microcarcinomas(PMC), 5 follicular adenomas (FA), 5 Hashimoto's thyroiditis (HT) and 12 nodular hyperplasias (NH) for significance as a diagnostic marker. Expression of p53 protein was evaluated immunohistochemically in sections of paraffinembedded tissue. Results: Statistical analysis showed significantly different expression of p53 in PTC versus other benign thyroid lesions (BTL).The diagnostic sensitivity and specificity were 85.0% and 72.7%, respectively. Overexpression of p53 protein was observed in 44 of the 93 PTC cases (47.3%), but no significant correlation between p53 protein overexpression and clinicopathologic features (age, size, multiplicity, lymph node metastasis, extrathyroidal extension and vascular invasion) was noted. Conclusions: p53 is valuable to distinguish PTC from other BTL, but there is no correlation between p53 protein overexpression and clinicopathologic features.

• Journal of Applied Biological Chemistry
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• v.43 no.1
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• pp.37-43
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• 2000

1,3,2-Dioxaphosphorinanes are suitable compounds for studying the stereochemistry of substitution at phosphorus. Cis- and trans-5-hydroxymethl-5-methyl-2-thiono-2ethoxy-1,3,2-dioxaphosphorinane were prepared, and their structures and stereochemistry unambiguously assigned by NMR and X-ray crystallography with acetoxy and 3,5-dinitrobenzoyloxy derivatives, respectively. Trans isomer gave $^{31}P$ NMR signal at higher field than cis isomer, and the ring proton Spectrum of cis isomer showed characteristic pattern for identifying its geometry. In X-ray crystallography they adopted a chair conformation with the ethoxy groups in the axial positions, and the sulfide groups in the equatorial positions. A flattening of the ring around the phosphorus center was noted, the POC bond angles were about $120^{\circ}$, and the C-O bonds in the ring were significantly longer than the C-O bond for the ethoxy group or the C-O bond for hydroxyl group.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.32 no.4
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• pp.307-312
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• 2019

Transient earth voltage (TEV) signals propagate on metal surfaces when partial discharge (PD) occurs due to the deterioration of insulation performance in the operation of gas-insulated switchgears (GIS). A TEV sensor has advantages of high sensitivity and convenient installation for detecting PD defects. However, the TEV sensor depends on imports in domestic and detailed studies have not been conducted. In this study, a sensor was designed and fabricated by the TEV principle and its response characteristics were evaluated for detecting PD defects, which were simulated as protrusion on conductor (POC), protrusion on enclosure (POE), and free moving particle (FMP) defects. Finally, the PD-induced TEV signals were measured and phase-resolved partial discharge (PRPD) patterns were analyzed to identify the type of defect.

• Proceedings of the Korea Information Processing Society Conference
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• 2006.05a
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• pp.1259-1262
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• 2006

H.264는 기존의 압축 표준들보다 월등한 압축률을 가지고 있어 다양한 멀티미디어 서비스에 적합하다. 특히 적은 양의 데이터 전송으로 서비스 받을 수 있는 모바일 기기에서는 빼놓을 수 없는 기술이 되었다. 현재 모바일 기기에서 영상 서비스는 하드웨어 기반의 디코더 형식으로 되어 있기 때문에 소프트웨어 기반의 디코더 개발이 시급하다. 그러기 위해서는 모바일 기기에서 탑재된 적은 용량의 메모리를 사용하므로써 빠른 재생이 가능해야 한다. 그래서 영상 복호화시에 사용되는 메모리 양을 줄일 수 있도록 참조픽처의 메모리를 관리하는 방법을 제안한다. 기존의 고정크기를 갖는 장기 참조픽처를 배제하고 단기 참조픽처로써 대체하고 비참조 픽처의 사용은 POC(Picture Order Count)에 전체 사용하지 않고 단지 순서를 정하기 위해 메모리 로드없이 순서 조합에 필요한 위치만 갖도록 하였다. 그러므로, 모바일 기기에서 메모리의 사용을 최대한 줄여 영상을 재생할 수 있도록 제안하였다.

• Proceedings of KOSOMES biannual meeting
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• 2009.06a
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• pp.137-143
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• 2009

진해만과 가덕도 주변 해역에서 2007년 2회(하계와 추계)에 걸쳐 표층 및 저층수 조사를 실시하여 수질 환경 특성을 파악하였다. 수온은 표층이 저층보다 높았는데 여름이 가을보다 표 저층간의 차이가 컸으며, 염분은 가덕도 남쪽에서 낙동강 물의 유입 영향으로 저염분을 나타내었다. 부유물질은 표층수의 경우 진해만 및 연안에서 높고 외해에서 낮았으며, 과거의 조사 농도 범위에 속하였다. POC는 계절별로 분포 차이가 있지만 유기물 유입원에 대한 근접성과 기초 생산아 영향을 받는 것으로 나타났다. COD는 표층에서 오염원의 영향이 많은 진해만에서 높고 외해로 가면서 낮아졌다. 여름에 진해만 일부 정점은 해역별 수질기준 III등급이었다. DO는 저층이 표층보다 낮았는데 특히 진해만 내완 외해의 깊을 수심 정점에서 차이가 크고, 하계에 성층에 의하여 수증간에 큰 자이를 나타내었다. 인산염-인과 규산염-규소는 저층수에서 용존산소가 낮아짐에 따라 높은 농도를 나타내는 경향이 강하였으며, 암모니아-질소도 내만의 저산소층에서 높은 농도를 보였다. 표층수의 용존 무기질소는 신항과 가덕도 주변에서 높고 진해만 서쪽 및 외해로 갈수록 낮아졌으며, 과거 조사 농도보다 낮고 좁은 변동 범위를 보였다. 총 질소와 총인도 외해역에서 낮은 농도였으며, 표층보다 저층이 높은 추세였고 여름에 더욱 뚜렷하였다. 총질소 평균 농도로는 해역별 수질기준과 I등급을 만족하였으나 정점별로는 $I{\sim}III$등급까지 변화가 컸는데 진해만 내의 저층 또는 외해의 깊은 수심을 갖는 정점에서 등급이 좋지 알았다. Chl-a는 진해만 내 또는 가덕수도에서 높은 분포였으며, 신항과 가덕도 남쪽에서는 과거보다 낮은 농도였다.

• Journal of Environmental Science International
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• v.11 no.9
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• pp.945-954
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• 2002

The objective okgf this study is understanding and evaluation of temporal and spatial variation of pollutant loads by input sources for water quality management in Kamak Bay. Flow rate of rivers and ditches ranges from about $2,592-63,072m^3/d$ in October to $864-55,296m^3/d$ in January. In particular, the R2 predominated flow rate among input sources. Total COD, BOD, DIN and DIP loadings in January were about 896kg/d, 718kg/d, 2,152kg/d, and 154kg/d, respectively, which exceeded those of October. Lower POC/TOC levels are estimated in R2, and also in October. Temporal variation of pollutant loads were closely related to the human activity. Total discharging loadings of BOD, TN and TP by unit loading estimation were 4,993.0kg/d, 2,558.7kg/d, and 289.2kg/d, respectively, and were mainly affected by the population. Runoff ratio of BOD was about 0.14 in January Mean $NH_4^＋_-N$ and $PO_4\;^{3-}-P$ loadings from sediment were 16.23mg/$m^2$/d and 7.26mg/$m^2$/d, respectively. For the improvement of water quality in this area, not only pollutant loads of rivers and ditches but also benthic flux from sediment should be reduced within the limits of the environmental capacity.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.61 no.2
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• pp.270-275
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• 2012

This paper presents a portable and compact optical device which can conveniently be used to perform a functional analysis of human liver function. The proposed system employed red/green LEDs, as a light source, and CMOS image sensor, which is commonly used in cellular phones. With this system, several blood serum samples have been evaluated for liver functional analysis by measuring light absorption level through the blood serum samples depending on aspartate aminotransferase (AST), alanine aminotransferase (ALT), and total bilirubin concentration. The light absorption through the blood serum samples containing AST, ALT, or total bilirubin can provide their concentrations. The green light absorption is more sensitive to the concentration of AST or ALT, and the red light absorption is more sensitive to the total bilirubuin concentration. Additional calibration steps were performed by using a MATLAB program in order to eliminate the light scattering effects from the extraneous particles existing in each blood serum sample. From the blind test, three standard light intensity curves through each enzyme have been obtained and the enzyme concentration values have been compared to those obtained from a commercially available biochemistry analyzer (Toshiba 200 FR). The average percent difference in the obtained concentrations from two systems for AST, ALT, and total bilirubin concentration came out to be 7.79%, 7.98%. and 7.56%, respectively, with the adjusted coefficient of determination (R2) higher than 0.98. This system can possibly lead to a low-cost and simple system that can be used as a point-of-care (POC) system in a condition without advanced equipments.

• The Proceeding of the Korean Institute of Electromagnetic Engineering and Science
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• v.10 no.3
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• pp.2-17
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• 1999

Interpolated second order polynomials(ISOP's) are proposed to design efficient cascaded integrator-comb(CIC)-based decimation filters for a programmable downconverter. It is shown that some simple ISOP's can effectively reduce the passband droop caused by CIC filtering with little degradation in aliasing attenuation. In addition, ISOP's are shown to be useful for simplifying halfband filters that usually follow CIC filtering. As a result, a modified half band filter(MHBF) is introduced which is simpler than conventional halfband filters. The proposed decimation filter for a programmable downconverter is a cascade of a CIC filter, an ISOP, MHBF's and a programmable finite impulse response(FIR) filter. A procedure for designing the decimation filter is developed. In particular, an optimization technique that simultaneously designs the decimation filter is developed. In particular, an optimization technique that simultaneously designs the ISOP and programmable FIR filters is presented. Design examples demonstrate that the proposed method leads to more efficient programmable downconverters than existing ones.