• 대한한방내과학회지
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• 제21권4호
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• pp.621-631
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• 2000

Objective : In this study, the medicine herbs above were directly treated to cultured normal lung cells and lung carcinoma cells, and the effects were investigated to develope new cancer treatments with increased anti-cancer efficiency as well as decreased side-effects and to suggest more useful clinical therapies. Materials and Methods : In the experiment, WI-26 VA lung normal cell line and A-427 lung carcinoma cell line were cultured. To observe the morphological change of the treated cells, were subjected to Giemsa staining and observed under Reflected Fluorescence microscope. To examine whether cell death occurred, cells observed under Reflected Fluorescence microscope, To investigate the degree of cell death in the nucleus, cells were screened by Laser cytometry ACAS 570. Results : Samgibopye-tang(Shenqibufei-tang) stimulated not only the growth of the normal cells but also that of the carcinoma cells, Wikyeung-tang(Weijing-tang) induced morphological change such as cytoplasmic constriction in the normal cells and the carcinoma cells, but it did not show any strong inhibitory effect on the cell growth. Samso-eum(Shensu-yin) caused severe cell damage in both cell lines, Eunkyo San(Yinqiao-san) significantly damaged the nuclei and caused weak cytoplasmic constriction in both cell lines, Normal cells treated with Gilgyeung-tang(Jingeng-tang) did not show any significant morphological change while some Gilgyeung-tang(Jingeng-tang) treated carcinoma cells were observed to have a normal cell-like shape, interestingly, conclusions : As the results above, Samgibopye-tang(Shenqibufei-tang), Wikyeung-tang(Weijing-tang), and Gilgyeung-tang(Jingeng-tang) helped the growth of both cell lines, and especially Samgibopye-tang(Shenqibufei-tang) showed the best effect, However, Samso-eum(Shensuyin) and Eunkyo-san(Yinqiao-san) caused lethal damage in the normal cells and also showed strong toxicity in the carcinoma cells.

• Tuberculosis and Respiratory Diseases
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• 제62권5호
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• pp.427-431
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• 2007

기관지 연관 림프조직 림프종은 비특이적인 호흡기 증상만을 나타내며, 전산화단층촬영에서 세기관지 폐포암, 림프구성 간질성 폐렴등과 뚜렷이 구분이 되지 않는 결절 외 림프종의 일종이다. 저자들은 비특이적인 호흡기 증상만을 나타내는 병변에 대해 침습적인 방법인 경피 미세흡입생검을 시행하여, 원발성 기관지 연관 림프조직 림프종으로 진단하였으며, 병리적 진단이 내려진 상태에서 치료를 목적으로 좌상엽 절제술을 시행하였다. 기관지 연관 림프조직 림프종은 서서히 진행되는 질환으로, 대부분 최종 진단이 늦어지는 경향을 보인다. 국소적 병변일 경우 외과적 수술로 완치가 가능한 질환이므로, 질환이 의심되는 경우 적극적 검사와 치료를 시도하는 것이 중요할 것으로 생각된다.