• Title/Summary/Keyword: A to Zoo

Search Result 355, Processing Time 0.025 seconds

Androgen Receptor-dependent Expression of Low-density Lipoprotein Receptor-related Protein 6 is Necessary for Prostate Cancer Cell Proliferation

  • Park, Eun;Kim, Eun Kyoung;Kim, Minkyoung;Ha, Jung Min;Kim, Young Whan;Jin, Seo Yeon;Shin, Hwa Kyoung;Ha, Hong Koo;Lee, Jeong Zoo;Bae, Sun Sik
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.19 no.3
    • /
    • pp.235-240
    • /
    • 2015
  • Androgen receptor (AR) signaling is important for prostate cancer (PCa) cell proliferation. Here, we showed that proliferation of hormone-sensitive prostate cancer cells such as LNCaP was significantly enhanced by testosterone stimulation whereas hormone-insensitive prostate cancer cells such as PC3 and VCaP did not respond to testosterone stimulation. Blocking of AR using bicalutamide abolished testosterone-induced proliferation of LNCaP cells. In addition, knockdown of AR blocked testosterone-induced proliferation of LNCaP cells. Basal expression of low-density lipoprotein receptor-related protein 6 (LRP6) was elevated in VCaP cells whereas stimulation of testosterone did not affect the expression of LRP6. However, expression of LRP6 in LNCaP cells was increased by testosterone stimulation. In addition, knockdown of LRP6 abrogated testosterone-induced proliferation of LNCaP cells. Given these results, we suggest that androgen-dependent expression of LRP6 plays a crucial role in hormone-sensitive prostate cancer cell proliferation.

A Study on Leaching of Vanadium and Nickel from Incineration Ash of Heavy Oil Fly Ash (중유회 소각재로부터 바나듐, 니켈 침출에 관한 기초적 연구)

  • 유연태;김병규;박경호;홍성웅
    • Resources Recycling
    • /
    • v.4 no.3
    • /
    • pp.32-39
    • /
    • 1995
  • Thc purpose of this study is to develop the efficient process for recovering vanadium and nickel from the incineralionash of the oil fly ash. In this paper, the physical and chemical properties of the incineration ash was examined, and theleaching characteristics of the incineration ash were investigated by water leaching and sulEuric acid leaching tcsls. The incinerationash of oil fly ash was mainly consisted of oxldes such as V,09, V,O,, NaVO,, Ni,(VO,)Z, Fe,O,, CaSO,, SiO,.Thc waler leaching showed low extraction of metallic components, while the sulfunc acid lcaching with high temperahlreand pressure increased the extraction of vanadium and nickcl considerably. For instance, the exlraction rates of the metalllccomponents on the sulfuric acid leaching were 99% for V and 45% for Ni at 90$^{\circ}$C with pH 0.5 H,SO,, and were86% for V and 75% far Ni at ZOO"C(64 psi) with pH 1.0 H-SO,. with pH 1.0 H-SO,.

  • PDF

A Study on the Development of Ability Women Specialist -Focused on the nursing specialist- (여성전문인의 능력발전에 관한 연구 - 전문간호사를 중심으로 -)

  • Kwon Ill Zoo
    • Journal of Korean Public Health Nursing
    • /
    • v.3 no.1
    • /
    • pp.101-119
    • /
    • 1989
  • In the present, since a five-year plan for economic development which was started in the early 60's has been successfully promoted for a quarter century, with consolidation in a department of social welfare in our country the participation. in economic society for women is more required than any other times. As a professional occupation for women is incereaing through a high-standard specialization, I think the upbringing for productive woman expert who has a strong motive of accomplishment as a developed person as well as a technical and skilful capacity which can be contributed to the growth of organization is very important. So in this study, I am evaluating the technical disposition of character of professional nurses working with hospital and also trying to supply the basic data being served to th extension of a skillful ability as a nurse, understanding the important factor related to it. The research method applied here is that we used 527 of formed questionnaires which were distributed to 7 University and General Hospitals, somewhat large in a scale, located in Seoul as an analytical material. It was performed between October 11, 1988 and October 18, 1988. An implement which was invented by Cho Moo-Sung is used after being amended and supplemented, which can measure the disposition of professional character. The formation of questionnaires of the disposition of character is 26 totally, 10 for Open-disposition, 11 for Active-disposition, 5 for wise-disposition, and it was measured. 'Ye', or 'No' through an one-half-standard and the environment of hospital organization is composed 12 questions from one point of 'Very Good' to 5 points of 'Very Bad.' Collected materials were analysed through an electronic calculation into the average value, the standard deflection, percentage, person correlative number, $X^2-test, m$ stepwise multiple regression. Summarizing the result from this research is as follows; 1. The average age of the subjective person of this investigation is 28.6 and the average career as a nurse is 6.0 years. 2. The Open-disposition that technical nurses showed is mostly half and half. 3. The Active-disposition of professional nurses was discovered affirmative largely and what they said in their questionnaires describes that they are very active answering $88.2\%$ for the disposition of self-control, $87.3\%$ for the people who think the training more seriously. 4. It was found out that the wise·disposition of technical nurse showed $90.7\%$ of 'Yes' about a new alternative of inquisitive question and we can see a progressive and profound aspect here. 5. As technical character of nurses, mutual relations between Active-disposition, Active-disposition, and wise­disposition were very profitably revealed as 0.42 in justice relations and also suggested that relations between Open-disposition, Active-disposition, and wise-disposition are 0.27 and 0.20 respectively. 6. What nurses recognize about the environment of hospital organization is reasonably acceptable while they feel very bad about rewards and punishments showing average 3.1 comparing to average 2.2 about time­control each other. Considering the prosperity of Active-disposition upon the result what I mentioned above, th possibility which is contributed to the productive improvement of hospital organization is very great and I think it can be more developed as a professional woman who has a strong motive of accomplishment, in advance.

  • PDF

Disaster Documentation through Oral History : Focus on Sinking of the MV Sewol (구술을 통한 재난 사고의 기록화 세월호 참사 관련 구술을 중심으로)

  • Song, Zoo Hyung
    • The Korean Journal of Archival Studies
    • /
    • no.44
    • /
    • pp.155-197
    • /
    • 2015
  • Disaster of Sewol took place in one year. Meanwhile, the victim's family and the call time record academics have tried to record it. Ansan activists have moved to objectives such as civil records committee also pivotal. The citizens committee under the dictation recording oral history team has a diverse group of people associated with the time issue. bereaved families were collected from the oral as well as volunteers, religious personnel, activists, Ansan citizens and various people. Disasters around the world is also an important event to remember and honor the people together, and one of the most effective means to record There it is establishing an oral history archive. Does not leave a lot of nature history of sudden disasters that occur, as well as a tribute record dictation telling people of diverse perspectives on events helps a lot closer to the reality of the event. Erected in the National September 11 Memorial Museum to honor the Sept. 11 attacks and provide a variety of programs to chaerok dictation of the people involved with 9/11. To remember the 2013 Boston Marathon bombing 'Our Marathon' of crowdsourcing digital archive was built. In the archives of the local universities and institutions were created to collaborate actively and gathering oral history. Pan Am Flight 103 pieces terror has established an archive from Syracuse University. Here, neither graduates, faculty, and to the victim's family and friends gather and oral hitory. Disaster-related Sewol neither should be able to be used as in the case of foreign well, and it should continue to honor the victims of the collection. It also ought to occasion again to avoid this disaster on earth.

Earth Construction Interior Applied to Healing Space : Focused on Biophilic Design Concept of Oriental Medical Clinic Interior (치유공간에 적용한 흙건축 인테리어 -한의원인테리어의 바이오필릭(Biophilic)디자인개념을 중심으로-)

  • Jeon, Chan Hee;Hwang, Hey Zoo
    • Journal of the Korean Society of Floral Art and Design
    • /
    • no.42
    • /
    • pp.37-62
    • /
    • 2020
  • The earth is a natural material that has natural healing power,,as a natural ingredient, it brings environmental friendliness, emotional. In this Research, for one of the methods to expand the benefits as a healing space, Construction of the Earth design and earth construction methods have been actively used for effectiveness of the Earth in the construction of the interior with the oriental medical clinic. By utilizing the concept of biophilic design as a healing environment design, symbolizing nature such as color, light, plants, flowers, and natural materials such as earth and wood was directed as oriental medicine interiors. In addition, the space was divided according to the movement of patients and used different Earth construction method to each of the space for the distinction and differentiation according to the characteristics of each space. At this time, the Earth was constructed with materials and finishing materials that meet the highest grade of HB (Healthy Building), an eco-friendly building material certification grade without additives, so that the interior and medical treatment concept can be done at the same time. By using Earth as the basis of elements in the construction, and the design of healing space, patient the concept of Biophillic as a healing environment design. This may serve as a technical, aesthetic, and cultural basis for constructing a healing space by Earth in the future-oriented alternative, it may lead to necessity of eco-friendly and ecological architecture, and it may be an opportunity to expand the application area of earth in architectural design.

A Study on the Trial Manufacture and Characteristics of Lamp Type Ozonizer (Lamp 형 오존발생기의 시작 및 특성에 관한 연구)

  • Kim, Sang-Ku;Song, Hyun-Jig;Kang, Cheon-Su;Park, Won-Zoo;Lee, Kwang-Sik;Lee, Dong-In
    • The Proceedings of the Korean Institute of Illuminating and Electrical Installation Engineers
    • /
    • v.10 no.6
    • /
    • pp.62-72
    • /
    • 1996
  • In this paper, ozonizer using U-type lamp(Olamp) has been designed and manufactured, which can perform a role of lighting source and ozonizer by using photo and chemical methods. The discharge, spectrum, illuminance, ozone concentration, ozone generation, ozone yield and sterilization characteristics of Olamp have been studied. The important conclusions obtained from this paper can be summa'||'&'||'not;rized as follows. As a result of spectrum characteristics for Olamp, ultraviolet ray of a short wave'||'&'||'not;lengths and a visible ray are radiated. The illuminance of Olamp was found to be useful for "color distinctive and intermittent works in the dark working spaces" in accordance with KS A 3011. The ozone concentration of gaseous phase is inversely proportional to quality of supplied gas. Also, ozone conce tration and generation of gaseous phase are rised more commercial oxygen gas than those trial air gas for constant quality of supplied gas. Ozone generation and ozone yield of gaseous phase are proportion'||'&'||'not;al to ozone concentration of gaseous phase. The characteristics of liquid ozone concentration at distilled water are proportional to circulating velocity of fermentation chamber and ozone concentration of gas'||'&'||'not;eous phase. As a result, the sterilization characteristics of Escherichia coli have been obtained more than 97[ % J.

  • PDF

The optical CT output signal characteristic according to temperature change (온도변화에 따른 광CT의 출력 특성)

  • Son, Hyun-Mok;Ahn, Mi-Kyoung;Heo, Soon-Young;Jeon, Jea-Il;Park, Won-Zoo;Lee, Kwang-Sik;Kim, Jung-Bae;Kim, Min-Soo
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
    • /
    • 2004.05a
    • /
    • pp.29-33
    • /
    • 2004
  • In this paper, we took the basic experiment in order to explore the characteristics of optical CT(optical current transformer) for measuring high current in a superhigh voltage condition using faraday effect and wrote that. We used the 1,310[nm] Laser Diode for the source of light and PIN-Photodiode for receiver. The transmission line of light was composed of the single-mode fiber of 30[m] which could maintain the state of polarization in the optical fiber. The range of current was from 400[A] to 1300[A]. In addition, the temperature ranged from $20[^{\circ}C}]\;to\;50[^{\circ}C]$. In a same experiment condition, a power magnitude increases in proportion as input current is increasing and temperature become low. The maximum ratio of error in temperature of $50[^{\circ}C]$ appears 0.15[%] and the 0.16[%], 1.24[%] and 0.07[%] is ratio of error in respectively $40[^{\circ}C],\;30[^{\circ}C],\;and\;20[^{\circ}C]$.

  • PDF

COMPREHENSIVE TREATMENT OF UNILATERAL COMPLETE CLEFT LIP AND PALATE (편측성 완전 구순구개열 환자의 포괄적 치료)

  • Lee, Jeong-Keun;Hwang, Byung-Nam;Choi, Eun-Zoo;Kim, Yong-Been
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.22 no.4
    • /
    • pp.430-435
    • /
    • 2000
  • Cleft lip and palate is one of the congenital anomalies which need comprehensive and multidisciplinary treatment plan because 1) oral cavity is an important organ with masticatory function as a start of digestive tract, 2) anatomic symmetry and balance is esthetically important in midfacial area, and 3) it is also important to prevent psycho-social problems by adequate restoration of normal facial appearance. There are many different protocols in the treatment of cleft lip and palate, but our department has adopted and modified the $Z{\"{u}}rich$ protocol, as published in the Journal of Korean Cleft Lip and Palate Association in 1998. The first challenge is feeding. Type of feeding aid ranges from simple obturators to active orthopedic appliances. In our department we use passive-type plate made up of soft and hard acrylic resin which permits normal maxillary growth. We use Millard's method to restore normal appearance and function of unilateral complete cleft lip. In consideration of both maxillary growth and phonetic problems, we first close soft palate at 18 months of age and delay the hard palate palatoplasty until 4 to 5 years of age. When soft palate is closed, posterior third of the hard palate is intentionally not denuded to allow normal maxillary growth. In hard palate palatoplasty the mucoperiosteum of affected site is not mobilized to permit residual growth of the maxilla. We have treated a patient with unilateral complete cleft lip and palate by Ajou protocol, which is a kind of modified $Z{\"{u}}rich$ protocol. It is as follows: Infantile orthopedics with passive-type plate such as Hotz plate, cheiloplasty with Millard's rotation-advancement flap, and two stage palatoplasty. It is followed by orthodontic treatment and secondary osteoplasty to augment cleft alveolus, orthognathic surgery, and finally rehabilitation with conventional prosthodontic treatment or implant installation. The result was good up to now, but we are later to investigate the final result with longitudinal follow-up study according to master plan by Ajou protocol.

  • PDF

A Study on SNS Records Management (기록관리 대상으로서 SNS 연구)

  • Song, Zoo-Hyung
    • The Korean Journal of Archival Studies
    • /
    • no.39
    • /
    • pp.101-138
    • /
    • 2014
  • This study examined the influence and meaning of SNS as the hot topic of our time from the archival perspective and also studied the 'SNS records management'. The many users mean a high accessibility and utilization of SNS, which increase the influence and value of SNS as a record. Politically, SNS is a tool that strengthens the communication among the voters, politicians and the public while economically, it is a window to accept the complaints of the customers and a marketing tool. In addition, the voices of social minorities are also recorded unlike in the traditional media, which makes the SNS record a method to gain the social variety and diversity. SNS is a place of formation of collective memory and collective memory itself. Furthermore, it can play the role of public sphere. It also is a place for generation of 'big data' in an archival sense. In addition, this study has classified the SNS records management into primary and secondary management that include record management entities, subjects, periods, methods, and causes. This study analyzed the history, status, and the meaning of SNS to assess the values and meanings as the preliminary study for the future SNS record management studies.

Flexible InGaP/GaAs Double-Junction Solar Cells Transferred onto Thin Metal Film (InGaP/GaAs 이중접합 기반의 고효율 플렉시블 태양전지 제조기술 연구)

  • Moon, Seungpil;Kim, Youngjo;Kim, Kangho;Kim, Chang Zoo;Jung, Sang Hyun;Shin, Hyun-Beom;Park, Kyung Ho;Park, Won-Kyu;Ahn, Yeon-Shik;Kang, Ho Kwan
    • Current Photovoltaic Research
    • /
    • v.4 no.3
    • /
    • pp.108-113
    • /
    • 2016
  • III-V compound semiconductor based thin film solar cells promise relatively higher power conversion efficiencies and better device reliability. In general, the thin film III-V solar cells are fabricated by an epitaxial lift-off process, which requires an $Al_xGa_{1-x}As$ ($x{\geq}0.8$) sacrificial layer and an inverted solar cell structure. However, the device performance of the inversely grown solar cell could be degraded due to the different internal diffusion conditions. In this study, InGaP/GaAs double-junction solar cells are inversely grown by MOCVD on GaAs (100) substrates. The thickness of the GaAs base layer is reduced to minimize the thermal budget during the growth. A wide band gap p-AlGaAs/n-InGaP tunnel junction structure is employed to connect the two subcells with minimal electrical loss. The solar cell structures are transferred on to thin metal films formed by Au electroplating. An AlAs layer with a thickness of 20 nm is used as a sacrificial layer, which is removed by a HF:Acetone (1:1) solution during the epitaxial lift-off process. As a result, the flexible InGaP/GaAs solar cell was fabricated successfully with an efficiency of 27.79% under AM1.5G illumination. The efficiency was kept at almost the same value after bending tests of 1,000 cycles with a radius of curvature of 10 mm.