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Effects of Excess Vitamin E and Cholesterol Supplements on Levels of Vitamin E and Cholesterol in Rat Serum and Liver (과량의 비타민 E 및 Cholesterol 첨가식이가 흰쥐의 혈청과 간의 비타민 E 및 Cholesterol 농도에 미치는 영향)

  • Hwang, K.D.;Kim, H.M.;Kim, J.M.;Lee, Y.C.
    • Journal of Nutrition and Health
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    • v.18 no.2
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    • pp.147-154
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    • 1985
  • The present study was undertaken to investigate the effects of excess vitamin E supple-mentation (0.5%) and cholesterol (0.5%) on levels of serum and liver vitamin E and cholesterol in two categories of rats, group A and group B. Rats in group A(45-65g) were fed experimental diets for 3 weeks ( I-C, II-E, III-Ch, IV-ECh). On the other hand rats in group B(45g-65g) were first fed control diet for 3 weeks and then fed experimental diets when they were 100-l20g for the subsequent 3 weeks ( I'-C, II'-E, III'-Ch, & IV'-ECh). The levels of serum vitamin E were higher in vitamin supplemented groups as expected. Dietary cholesterol showed a tendency to lower serum vitamin E levels of vitamin E supplemented groups. Serum cholesterol levels tended to stay in a narrow range showing resistancy to dietary cholesterol and were not affected by vitamin E status. Whereas vitamin E supplementation seemed to lower the levels of hepatic cholesterol in both groups A & B( I-C, I'-C vs II-E, II'-E ), simultaneous supplementation of vitamin E with 0.5% cholesterol appeared to increase further the hepatic cholesterol levels which were already increased by cholesterol feeding ( IV-ECh, IV'-ECh, vs III- Ch, III'-Ch). Hepatic vitamin A levels decreased as rats grew older during the experimental period. Even though vitamin A levels did not differ from each other significantly, excess amount of vitamin E supplementation in group B seemed to show a tendency to decrease the vitamin A storage in liver.

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A Design of Communication Network Architecture for E-Navigation Services (E-Navigation 서비스 제공을 위한 통신망 아키텍처의 설계)

  • Jeong, Jung-Sik;Kim, Sun-Young
    • Journal of Navigation and Port Research
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    • v.32 no.1
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    • pp.37-45
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    • 2008
  • The research on an E-Navigation(E-Nav) strategy development has recently carried out by the IMO sub-committee on safety of navigation(NAV). The design of communication system architecture is a key factor in the E-Nav strategy development and it may drive the direction of a national R&D project on future navigational and marine communication systems. This study aims at designing a standard model of E-Nav communication network architecture, which enhances navigational safety and provides additional benefits in marine transportation. To achieve this purpose, authors have suggested E-Nav services, which are divided into five categories, i.e., safety and security, maritime meteorology, distress, business, and infotainment, by analyzing the related user requirements. As results, this paper proposes the E-Nav communication network architecture that consists of the navigation and communication equipments.

Isolation and Characterization of Eukaryotic Translation Initiation Factor 5A (eIF-5A) from Potato (감자로부터 Eukaryotic Translation Initiation Factor 5A (elF-5A) 유전자의 동정 및 발현 분석)

  • 인준교;신동호;최관삼;양덕춘
    • Korean Journal of Plant Tissue Culture
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    • v.28 no.5
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    • pp.283-287
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    • 2001
  • Differential display based on PCR was employed to identify genes expressed during tuber-developing stage of potato (Solanum tuberosum L. cv. Irish Cobbler). An eukaryotic initiation factor 5A (eIF-5A) clone isolated from a cDNA library constructed with developing micro-tuber using a probe of PCR fragment. We isolated three positive clones and ore of them contained open reading frame. This clone revealed high sequence similarity to tomato eIF 5A cDNA. At the DNA level, there is 94.8% identity with the tomato eIF-5A4, whereas at the protein level there is a high identity with 97.5%. The potato eIF 5A clone is 716 bp in length and contains a single open reading frame from 57 to 539 bp, a 56 bp 5'-untranslated region and a 177 bp 3'-untranslated region. The deduced protein composed of 160 amino acid residues, with a predicted molecular mass of 17.4 kD and an estimated pl of 5.5. The sequence of 12 (STSKTGKHGHAK) amino acids among eIF-5A proteins is perfectly conserved from yeast to human. That sequence in potato eIF-5A protein is also conserved at position 46 to 57 amino acid. This region embeds the post-translational modification site of the lysine residue (at the seventh K) to hypusine that is crucial to eIF-5A activity. The northern blot analysis of eIF5A has shown abundant expression, mainly in flower organs (stamen, ovary, petal, sepal), fruit and stolen.

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L'identità e l'ibridità oltre il confine della Mitteleuropa danubiana in Danubio di Claudio Magris (클라우디오 마그리스의 『다뉴브강』에 나타난 다뉴브강 중부유럽의 탈경계적인 정체성과 혼종성)

  • Lee, Seung Su
    • Lettere Italiane
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    • no.36
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    • pp.73-97
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    • 2012
  • Danubio è un 'diario di viaggio' dalle sorgenti del fiume fino al Mare Nero, attraverso città importantissime o paesi, ampi paesaggi, popoli, costumi, letterature e lingue diverse. Un itinerario fra romanzo e saggio che racconta la cultura come esperienza esistenziale e ricostruisce a mosaico le civiltà di Mitteleuropa rintracciandone il profilo nei segni della grande storia e nelle effimere tracce della vita quotidiana. L'idea di Mitteleuropa nasce a meta dell'Ottocento per indicare un spazio politico e soprattutto economico egemonizzato dai tedeschi e dagli ungheresi, che piu tardi diventa il simbolo di programmi nazionalisti tedeschi e che poi diventa una dimensione sovranazionale, qualcoca di comune e sottostante a tutte le diverse nazionalità e culture di tante realtà diverse. La Mitteleuropa 'hinternazionale', oggi idealizzata quale armonia di popoli diversi, è stata una realtà dell'impero absburgico, nella sua ultima stagione, una tolleranzte convivenza comprensibiilmente rimpianta dopo la sua fine, anche per il confronto con la barbarie totalitaria che le è succeduta, fra le due guerre mondiali, nello spazio danubiano. L'arte absburgica di governo non vuole imporre una rigida unità ai vari popoli, bensi lasciarli sussistere e convivere nella loro eterogeneità. Secondo Claudio Magris, il Danubio è il simbolo della frontiera, perché il Danubio è un fiume che passa attraverso tante frontiere, è quindi simbolo della necessità e della difficoltà di attraversare frontiere, non soltanto nazionali, politiche, sociali, ma anche psicologiche, culturali, religiose. La nostra identità è sempre fragile e noi dobbiamo accettare questa fragilità, poiché mutiamo nel tempo. L'identità fatta di mescolanze, di sottrazioni e di elisioni non fosse soltanto il destino degli epigoni danubiani, bensì una condizione storica generale, l'esistenza di ogni individuo. Magris dice che siccome nessun popolo, nessuna cultra come nessun individuo sono privi di colpe storiche, rendersi impietosamente conto dei difetti e delle oscurità di tutti, e di se stessi, può essere una proficua premessa di convivenza civile e tollerante. Magris dice che la letteratura è di perse stessa una frontiera, una soglia, una zona sul limitare e insegna a varcare i limiti, ma consiste nel tracciare dei limiti, senza i quali non puo esistere e nemmeno la tensione a superarli per raggiungere qualcosa di piu alto e di piú umano.

Functionality design of the e-Science workbench (e-Science 워크벤치 기능 설계)

  • Lee, June H.;Nam, Dukyun;Kim, Byungsang;Suh, Youngkyoon;Hwang, Soonwook
    • Proceedings of the Korea Contents Association Conference
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    • 2007.11a
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    • pp.259-264
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    • 2007
  • To efficiently utilize an e-Science application service which is built on a grid computing environment, it is vital to develop technologies for integrating each e-Science application services into a workflow and for executing the workflow on a cooperative environment. In this paper, we analyze the requirements of e-AIRS system, one of the e-Science environment of aerospace research community. From the requirement analysis, we propose the required functionality and the architecture of e-Science workbench for effective utilization of e-Science services on cooperative environment.

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Analysis of Telomerase Activity by HPV E6/E7 Expression in SW13 (인간 파필로마 바이러스 E6/ E7에 의한 Telomerase 활성)

  • Kim, Young-Kwon;Seo, Choong-Won;Kim, Sang-Ha;Park, Yuk-Pheel
    • Korean Journal of Clinical Laboratory Science
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    • v.39 no.1
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    • pp.1-6
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    • 2007
  • Cervical cancer is one of the most prevalent cancers developed in women worldwide, and human papillomavirus(HPV) type 16 is the most common agent linked to human cerivical carcinoma. Viral oncogenes E6 and E7 are selectively retained and expressed in carcinoma cells infected with human papillomavirus type 16 and cooperate with each other in the immortalization and transformation of primary keratinocytes. Because the HPV oncogenesis mechanism was not completely solved, more thorough studies are required. ln the present study, we investigated the telomere independent role of telomerase in HPV oncogenesis, we constructed the E6 mutant, E7, E6/E7 and hTERT over-expressed stable cells with a telomerase negative cell line, SW13. Expressions of inserted genes were measured by RT-PCR. E6, E7 and hTERT genes were well expressed in each cell lines when compared with the control groups. By analyzing the cell morphology under the microscope, hTERT clone size was a smaller than the mock control but oncogene expressed clones had a slightly lengthened marginal region. In addition, hTERT cells also has a tendency of brief dividing time compared to the mock control. To determine whether telomerase activity was associated with a HPV oncogenesis by oncoprotein expression, we performed the PCR based TRAP assay and a Northern blot analysis. In TRAP assay data, telomerase activities in hTERT and oncogene clones increased compared to the mock control. In addition, SW13/E6/E7 cells showed an extremely increased activity compared to the other clones. Induced hTERT mRNA by E6/E7 wasn't, however, detected in Northern blotting. In conclusion, these findings suggest that telomerase activity is closely associated with the HPV oncogenesis and E6/E7 co-expression is a most important factor of telomerase activity.

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ON STRONGLY θ-e-CONTINUOUS FUNCTIONS

  • Ozkoc, Murad;Aslim, Gulhan
    • Bulletin of the Korean Mathematical Society
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    • v.47 no.5
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    • pp.1025-1036
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    • 2010
  • A new class of generalized open sets in a topological space, called e-open sets, is introduced and some properties are obtained by Ekici [6]. This class is contained in the class of $\delta$-semi-preopen (or $\delta-\beta$-open) sets and weaker than both $\delta$-semiopen sets and $\delta$-preopen sets. In order to investigate some different properties we introduce two strong form of e-open sets called e-regular sets and e-$\theta$-open sets. By means of e-$\theta$-open sets we also introduce a new class of functions called strongly $\theta$-e-continuous functions which is a generalization of $\theta$-precontinuous functions. Some characterizations concerning strongly $\theta$-e-continuous functions are obtained.

A Study on the Design and Development of eCRM Using Financial Goods Recommendation Expert System (금융상품추천 전문가시스템을 이용한 은행의 eCRM 설게 및 구축 방안에 관한 연구)

  • Kim, Ha-Kyun;Jeong, Seok-Chan
    • The Journal of Society for e-Business Studies
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    • v.9 no.3
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    • pp.191-205
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    • 2004
  • In banking industry, as competition of retail finance is intensive, there appeared eCRM which is a kind of marketing strategy, not only screening good customers but also doing one-to-one marketing for improving customer royalty and satisfaction of goods and service of bank. The strategic importance of eCRM is increasing more and more. We studied bank to use the advantage of expert system and eCRM. The expert system is used as a tool to analyze eCRM. In this paper, first, we presented an eCRM system architecture using expert systems in banking business. Secondly, a bank financial goods recommendation system using expert system is designed and developed. Customers will receive the good quality financial services from the expert system and banks also will acquire the good quality customer data from the expert system.

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A Study on the Implementation of e-B/L for the Dissemination of Global e-Trade (글로벌 전자무역 확산을 위한 전자 선하증권 도입과 구현전략에 관한 연구)

  • Lee, Sang-Jin
    • International Commerce and Information Review
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    • v.10 no.1
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    • pp.193-214
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    • 2008
  • This study aims to examine similarities and differences of each e-B/L types as well as identify problems of e-B/L utilization and directions for improvement. Especially, it suggests strategies for the realization of e-B/L through reviewing and analyzing commercial types of e-B/L, which have been developed so far. Although e-B/L succeeded in realizing the function as a certificate of title and its distribution value, it has not been fully implemented due to operational problems. Subsequently, e-B/L was realized in the Bolero project as an attempt of system to make up for shortcomings in the failure of previous e-B/L types, but it has still a number of problems. To solve this problem and make use of e-B/L more efficiently, this study focuses on the specific ways to introduce e-B/L and suggest directions for the development of e-Nego system. Preparation of electronic documents is a prerequisite for the development of the e-Nego system, taking distribution of electronic documents into consideration. Next, compatibility of electronic documentation and paper-based documents should be realized, with the guarantee of authenticity of electronic documents.

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A study on the Analysis and Forecast of Effect Factors in e-Learning Reuse Intention Using Rule Induction Techniques (규칙유도기법을 이용한 이러닝 시스템의 재이용의도 영향요인 분석 및 예측에 관한 연구)

  • Bae, Jae-Kwon;Kim, Jin-Hwa;Jeong, Hwa-Min
    • Journal of Information Technology Applications and Management
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    • v.17 no.2
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    • pp.71-90
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    • 2010
  • Electronic learning(or e-learning) has created hype for companies, universities, and other educational institutions. It has led to the phenomenal growth in the use of web-based learning and experimentation with multimedia, video conferencing, and internet-based technologies. Many researchers are interested in the factors that affect to the performance of e-learning or e-learning services. In this sense, this study is aimed at proposing e-learning system reuse prediction models in which e-learner intention to reuse influence factors(i.e., system accessibility, system stability, information clarity, information validity, self-regulated efficacy, computer self-efficacy, perceived usefulness, perceived ease of use, flow, and parental expectation) affect e-learner intention to reuse positively. A web survey was conducted for the full members of the e-learning education institute A in Seoul, Republic of Korea, an exclusive e-learning company that provides real time video lectures via the desktop conferencing system. The web survey was conducted for 20 days from November 5, 2009, through the e-learning web site of the company A. In this study, three data mining techniques were used : the multivariate discriminant analysis, CART, and C5.0 algorithm. This study was conducted to provide the e-learning service providers, e-learning operators, and contents developers with marketing and management strategies for improving the e-learning service companies, based on the data mining analysis results.

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