• Korean Journal of Environmental Agriculture
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• v.7 no.2
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• pp.92-95
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• 1988

A Pot experiment was conducted to study the uptake of $Sr^{90}$ by rice plants in five different types of paddy soils and its distribution in these plants as a function of the age of the rice. The uptake of $Sr^{90}$ by rice plants increased with the growth of the aboveground mass of the plants from the planting period, but $Sr^{90}$ content per unit of dry matter decreased as the organic mass of the plants increased during the vegetative growing period, except for the time of ripening. The content of Ca and $Sr^{90}$ in rice plants was higher in the stem and leaves than in grain parts in general. However, Ca content was decreased in the stem and increased in the grain part with the growth of the rice plant ; but $Sr^{90}$ content was increased in the leaves and decreased in the stem and grain parts.

• Nuclear Engineering and Technology
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• v.15 no.2
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• pp.110-116
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• 1983

The absorption and translocation of strontium-90 by soybean plant, Glycine max, was studied by applying strontium-90 solution on the foliage or on the soil surface right after the first flowering time under greenhouse conditions. The results are summarized as follows. In the foliar application of strontium-90, only a small portion of the radioactivity was translocated to other parts of the plant and most of it remained in the applied leaves, which should cause soil contamination after falling. In the soil surface application of strontium-90, much of the radioactivity was absorbed through the root and translocated to stems and leaves by different patterns depending on the growth stage.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.43 no.2 s.344
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• pp.76-80
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• 2006

In this paper, broadband balanced amplifier has been realized with Three-Arm Branch $90^{\circ}$ Hybrid Coupler at center frequency 2GHz. $90^{\circ}$ Hybrid Branch-Line Coupler has been compared with Three-Arm Branch $90^{\circ}$ Hybrid Coupler. The bandwidth VSWR and gain or proposed amplifier have been 480MHz, 1.06 and 15.47dB, respectively.

• Biomedical Science Letters
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• v.12 no.4
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• pp.419-425
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• 2006

Phospholipase $C-{\gamma}1\;(PLC-{\gamma}1)$ is an important signaling molecule for cell proliferation and differentiation. $PLC-{\gamma}1$ contains two pleckstrin homology (PH) domains, which are responsible for protein-protein interaction and protein-lipid interaction. $PLC-{\gamma}1$ also has two Src homology (SH)2 domains and a SH3 domain, which are responsible for protein- protein interaction. To identity proteins that specifically binds to PH domain of $PLC-{\gamma}1$, we prepared and incubated the glutathione S-transferase(GST)-fused PH domains of $PLC-{\gamma}1$ with COS7 cell lysate. We found that 90 kDa protein specifically binds to PH domain of $PLC-{\gamma}1$. By matrix-assisted laser desorption ionization time of flight-mass spectrometry, the 90 kDa protein revealed to be heat shock protein (Hsp) $90{\beta}$. Hsp $90{\beta}$ is a molecular chaperone that stabilizes and facilitates the folding of proteins that are involved in cell signaling, including receptors for steroids hormones and a variety of protein kinases. To know whether Hsp $90{\beta}$ affects on $PLC-{\gamma}1$ activity, we performed $PIP_2$ hydrolyzing activity of $PLC-{\gamma}1$ in the presence of purified Hsp $90{\beta}$ in vitro. Our results show that the Hsp $90{\beta}$ dose-dependently inhibits the enzymatic activity of $PLC-{\gamma}1$ and further suggest that Hsp $90{\beta}$ regulates cell growth and differentiation via regulation of $PLC-{\gamma}1$ activity.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2005.06a
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• pp.248-254
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• 2005

This paper presents a quantitative method of sequential separation of $^{90}Sr,\;^{241}Am$ and Pu nuclides with an anion exchange resin and a Sr-Spec resin. The Pu isotopes were purified with an anion exchange resin. The americium and strontium fractions were separated from the matrix elements with an oxalate co-precipitation method. Americium fraction was separated from the strontium fraction with iron co-precipitation method and purified from lanthanides with anion exchange resin. Strontium-90 was purified from other hindrance elements with the Sr-Spec resin after oxalate co-precipitation. The measurement of Pu and Am isotopes was carried out by an ${\alpha}$-spectrometer. Strontium-90 was measured by a liquid scintillation counter. The radiochemical procedure of $^{90}Sr,\;^{241}Am$ and Pu nuclides investigated in this study has been validated by application to IAEA-Reference soils.

• BMB Reports
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• v.52 no.12
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• pp.706-711
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• 2019

Cisplatin (Cis-DDP) is one of the most widely used anti-cancer drugs. It is applicable to many types of cancer, including lung, bladder, and breast cancer. However, its use is now limited because of drug resistance. p90 ribosomal S6 kinase (p90RSK) is one of the downstream effectors in the extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) pathway and high expression of p90RSK is observed in human breast cancer tissues. Therefore, we investigated the role of p90RSK in the Cis-DDP resistance-related signaling pathway and epithelial-mesenchymal transition (EMT) in breast cancer cells. First, we discovered that MDA-MB-231 cells exhibited more Cis-DDP resistance than other breast cancer cells, including MCF-7 and BT549 cells. Cis-DDP increased p90RSK activation, whereas the inactivation of p90RSK using a small interfering RNA (siRNA) or dominant-negative kinase mutant plasmid overexpression significantly reduced Cis-DDP-induced cell proliferation and migration via the inhibition of matrix metallopeptidase (MMP)2 and MMP9 in MDA-MB-231 cells. In addition, p90RSK activation was involved in EMT via the upregulation of mRNA expression, including that of Snail, Twist, ZEB1, N-cadherin, and vimentin. We also investigated NF-κB, the upstream regulator of EMT markers, and discovered that Cis-DDP treatment led to NF-κB translocation in the nucleus as well as its promoter activity. Our results suggest that targeting p90RSK would be a good strategy to increase Cis-DDP sensitivity in triple-negative breast cancers.

• Journal of Oral Medicine and Pain
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• v.40 no.1
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• pp.35-40
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• 2015

Purpose: This study aims to assess the psychological characteristics of patients with iatrogenic damage of the trigeminal nerve using Symptom Checklist-90-Revised (SCL-90-R). Methods: A total of 22 patients who visited the clinic of Department of Oral Medicine, School of Dentistry, Chosun University were evaluated in the months from December 2012 to December 2014. Patients were included in the study if they presented with reported sensory changes due to iatrogenic trigeminal nerve injury. A total of 37 control group who has no symptoms of pain and sensory change were included in the study. All participants filled out the SCL-90-R instrument to assess psychosocial symptoms. Results: The T-scores of most of the SCL-90-R symptom dimensions were within normal range (less than 55) in the patients and the control group. The patients group showed higher T-scores of SCL-90-R than those of the control group, with statistically significance of somatization, anxiety, psychoticism, and positive symptoms distress. Female patients group had higher Tscores of SCL-90-R than those of male patients group, but there was no statistical difference, except for the positive symptom global index. The chronic patients group showed higher Tscores of SCL-90-R than those of the acute patients group, but there was no statistical difference, except for the Positive symptom global index. Conclusions: According to the psychological assessment of iatrogenic trigeminal nerve injury patients using SCL-90-R, the patients group, as compared to the control group shows a significantly higher score for somatization, anxiety, and psychoticism. Therefore, assessment of psychological state would be considered to treat patients with iatrogenic trigeminal nerve injury.

• Analytical Science and Technology
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• v.18 no.6
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• pp.469-474
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• 2005

This paper presents a quantitative method of sequential separation of $^{90}Sr$, $^{241}Am$ and Pu radionuclides with an anion exchange resin and a Sr-Spec resin. The Pu isotopes were purified with an anion exchange resin. The americium and strontium fractions were separated from the matrix elements with an oxalate co-precipitation method. Americium fraction was separated from the strontium fraction with iron co-precipitation method and purified from lanthanides with anion exchange resin. Strontium-90 was purified from other hindrance elements with the Sr-Spec resin after oxalate co-precipitation. The measurement of Pu and Am isotopes was carried out by an ${\alpha}$-spectrometer. Strontium-90 was measured by a liquid scintillation counter. The radiochemical procedure of $^{90}Sr$, $^{241}Am$ and Pu radionuclides investigated in this study has been validated by application to IAEA-Reference soils.

• Journal of Oriental Neuropsychiatry
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• v.19 no.1
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• pp.55-70
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• 2008

Objective : The aim of this study is to investigate and measure the Test-anxiety of college students in OO Oriental Medicine by using Korea's version-Test Anxiey Inventory(K-TAI-K), State-Trait Anxiety Inventory(STAI), Symptom Check List-90-Revision(SCL-90-R), etc. Methods : We studied 181 students who being at OO College of Oriental Medicine in second semester, 2007 We used some questionaries like K-TAI-K, STAI, SCL-90-R , College Life Satisfacaion, Life Event Questionnaire. Results and Conclusions : 1.141 persons(83,43%) of students feel the largest test anxiety before test. 18 persons(9.94%) of students feel the largest test anxiety after test. 2.The 1st grade students of preparatory course and 4th grade students of regular course have the lowest score in State Anxiety Inventory and obsessive-compulsive of SCL-90-R. The 2nd grade students of regular course have the lowest score in State Anxiety Inventory and obsessive-compulsive of SCL-90-R 3. Students who failed in test one time have the lowest score , and who failed in test more than two times have the highest score in K-TAl-K Students who failed one time in grade promotion more than two times showed high score in second K-TAI-K. 4. The higher grade, the lower score in College Life Satisfaction. The scores of College Life Satisfaction have negative correlations with those of K-TAI-K, STAI SCL-90-R except phobic anxiety, 5. The scores of Life Event Questionnaire have positive correlations with those of K-TAI-K, STAI and SCL-90-R except phobic anxiety. 6. The scores of K-TAl-K have positive correlations with those of STAI, SCL-90-R, College Life Satisfaction and Life Event Questionnaire. A correlation coefficient of obsessive-compulsive scale is highest, anxiety scale is second, interpersonal sensitivity scale is third, depression scale is fourth high among the scales of SCL-90-R.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.18 no.9
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• pp.1064-1069
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• 2007

This paper proposes the highly miniaturized active $90^{\circ} power combiner for application to MMIC. Conventional passive $90^{\circ} power combiners can't be integrated on MMIC because of their very larger size. Therefore, the highly miniaturized $90^{\circ} power combiners are required for a development of highly integrated MMIC. For this paper, the highly miniaturized active $90^{\circ} power combiner employing InGaP/GaAs HBT was fabricated on GaAs substrate for application to highly integrated MMIC. A size of fabricated active $90^{\circ} power combiner was $2.42{\times}1.05$ mm, which was 2.2 % of conventional passive $90^{\circ} power combiner. The fabricated active $90^{\circ} power combiner showed a gain characteristic about 10 dB and a good phase-difference coupling characteristic of $-92.6^{\circ} than conventional passive $90^{\circ} power combiner at 2.4 GHz. The highly miniaturized active $90^{\circ} power combiner exhibited good RF performances comparable to conventional passive $90^{\circ} power combiners. This work is the first report of an active $90^{\circ} power combiner.