• Journal of Radiation Protection and Research
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• v.20 no.2
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• pp.123-128
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• 1995

The concentration of Cs-137 and Sr-90 has been analyzed in soils around Taejon region. A correalation was found between the concentration of Cs-137 and the organic matter content. The mean value of Cs-137 was 14.37Bq/kg-dry and that of Sr-90 was 7.95Bq/kg-dry in undisturbed soils around Taejon region. The concentration ratio of Cs-137/Sr-90 was 1.99. The distribution of Cs-137 and Sr-90 was similar to cumulative fallout level and had been more affected by nuclear weapons test than by the chernobyl accident.

• Nuclear Engineering and Technology
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• v.3 no.1
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• pp.9-13
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• 1971

The levels of strontium-90 in milk produced in Korea were determined during the past six years. Milk samples were collected from dairies and market shops in seoul area. Strontium-90 in milk was separated from calcium using fuming nitric acid and purified radiochemically. After seculear equilibrium was completed, the radioactivity of yttrium-90 was counted in a low background beta counting system. The determination of stable calcium in milk was also made by volu-metric method using 0. 1 N potassium permanganate solution. The highest value of 34.9 pCi $^{90}$ Sr/g-Ca was determined in August, 1966 and the lowest value was 7.5 pCi $^{90}$ Sr/g-Ca in August, 1967. From the result we can say that levels of strontium-90 are decreasing year after year and are far bellow the maximum permissible level recommended by International Committe on Radiation Protection.

• Nuclear Engineering and Technology
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• v.16 no.3
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• pp.131-135
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• 1984

The determination of Sr-90 in 93 Korean vertebrae was carried out using modified method of tri-n-butyl phosphate extraction. As a result, the average content of Sr-90 in Korean vertebrae was 2.29 pCi/g Ca in the female and 1.73 pCi/g Ca in the male and the average level of both sexes was 2.01 pCi/g Ca, which was slightly higher than those of other countries. On the other hand, the Sr-90 injected into intraperitonal cavity of rat was accumulated in bones mostly and distributed evenly to various types of hones. The rate of accumulation and removal was not dependent on the amount of Sr-90 injected and over one half Sr-90 injected was accumulated in bones within one day and then it was removed gradually after two days from the injection.

• Korean Journal of Applied Biomechanics
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• v.18 no.1
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• pp.85-95
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• 2008

This study is analyzing about application of taping by movement about shoulder joint's isometric contraction. M. college students take part in experiment. WEMG-8 and HUMAC system are used. Findings were as follows: EMG of muscle's MVIC at each angle before and after taping. 1. In flexion, EMG with taping is effective for supra spinatus at $0^{\circ}{\cdot}45^{\circ}{\cdot}90^{\circ}$, anterior deltoid at $0^{\circ}{\cdot}45^{\circ}$ and biceps brachii at $0^{\circ}{\cdot}90^{\circ}$. 2. In extension, EMG with taping is effective for triceps brachii at $0^{\circ}$, latissimus dorsi at $90^{\circ}$ and posterior deltoid at $45^{\circ}{\cdot}90^{\circ}$. 3. Each angle viewpoint, EMG of latissimus dorsi in extension can be arranged in its high order as $90^{\circ}<45^{\circ}$, $0^{\circ}$ without taping and $90^{\circ}<0^{\circ}$ respectively. EMG of posterior deltoid in extension is in its high order as $90^{\circ}<45^{\circ}<0^{\circ}$ without taping and $90^{\circ}<0^{\circ}$.

• Biomolecules & Therapeutics
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• v.24 no.5
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• pp.453-468
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• 2016

There is a conserved ATPase domain in topoisomerase II (topo II) and heat shock protein 90 (Hsp90) which belong to the GHKL (gyrase, Hsp90, histidine kinase, and MutL) family. The inhibitors that target each of topo II and Hsp90 are intensively studied as anti-cancer drugs since they play very important roles in cell proliferation and survival. Therefore the development of dual targeting anti-cancer drugs for topo II and Hsp90 is suggested to be a promising area. The topo II and Hsp90 inhibitors, known to bind to their ATP binding site, were searched. All the inhibitors investigated were docked to both topo II and Hsp90. Four candidate compounds as possible dual inhibitors were selected by analyzing the molecular docking study. The pharmacophore model of dual inhibitors for topo II and Hsp90 were generated and the design of novel dual inhibitor was proposed.

• Journal of the Korean Magnetics Society
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• v.2 no.1
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• pp.1-7
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• 1992

Deuterium was injected into melt-spun ribbons of ${\alpha}-Fe_{90}Zr_{10}$ using the electrolytic hydrogenation method, and the magnetic properties of these ${\alpha}-D_{x}Fe_{90}Zr_{10}$ ribbons were studied. By comparing these results with those of ${\alpha}-H_{x}Fe_{91}Zr_{9}$, the effects of phonons to magnetic properties were investigated. The Curie temperature $T_{c}$, and the spontaneous magnetizations of the $D_{47}Fe_{90}Zr_{10}$ and the $Fe_{90}Zr_{10}$ were studied using the Mbssbauer spectroscopy. From these investigations, it was found that the Curie temperature of $D_{x}Fe_{90}Zr_{10}$ was 75K higher than that of $Fe_{90}Zr_{10}$. It was believed that this indicated the importance of local deformation to the amorphous magnetism. Also by comparing the spontaneous magnetizations of $D_{47}Fe_{90}Zr_{10}$ with those of $Fe_{90}Zr_{10}$ as a function of temperature, it was found that the deuterium injection reduced the fluctuation of exchange integral.

• Horticultural Science & Technology
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• v.31 no.2
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• pp.179-185
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• 2013

This study was carried out to find a reasonable irrigation method of a nutrient solution for the phenolic foam slab (foam LC) used in a trial experiment to substitute the rockwool slab in the production of paprika (Capsicum annuum 'Veyron'). 100, 90, and 80 mL of a nutrient solution was supplied per plant each time when the accumulated radiation reached to 100, $90J{\cdot}cm^{-2}$, and they were named as the 100-100, 90-90, and 90-80 treatment, respectively. The drain percentage per plant of the 100-100 treatment was high by 33.8% in rockwool and 36.7% in foam LC (Lettuce Cube) and that of 90-80 treatment was low by 30.4% and 33.7%. The water content and EC of the rockwool slab were maintained in the range of 63.6-68.9% and $4.4-5.1mS{\cdot}cm^{-1}$, while those of the foam LC slab were in the range of 52.9-58.8% and $5.5-6.5mS{\cdot}cm^{-1}$. The plant height and leaf size of the 100-100 and 90-90 treatments increased in a similar manner, while those of the 90-80 treatment decreased and those of the rockwool were greater than those of the foam LC. The fruit size and weight of the 100-100 and 90-90 treatments were similarly bigger and heavier than those of the 90-80 treatment. The number of fruits harvested per plant was the greatest in the 90-80 treatment with 8 and 8.3 fruits in the rockwool and foam LC. The number of marketable fruits in the rockwool and foam LC was the greatest with 18.1 and 18.2, respectively, in the 90-90 treatment, while that in the 90-80 treatment was 17.2 and 16.8, respectively. The number of unmarketable fruits of the 90-80 treatment was the greatest (1.7-1.8 fruits per plant) in both the rockwool and foam LC, and most of them were small sized or blossom end rot fruits. The yield of the 90-90 treatment was the greatest among the irrigation.

• Korean Journal of Environmental Biology
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• v.33 no.4
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• pp.433-440
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• 2015

The Apostichopus japonicus is an important species in some Asia countries including Korea, China and Japan. The purpose of the present study was to investigate the differential gene expression of heat shock protein90 (Hsp90) and ferritin as a biomarker for the thermal stress during water temperature rising in the sea cucumber, A. japonicus. The A. japonicus (1.4 g) was cultured in incubator of separate temperature ($15^{\circ}C$, $20^{\circ}C$, $25^{\circ}C$ and $30^{\circ}C$) for each 0, 3, 6, 12, 24, 48 hours. The mRNA expression levels of Hsp90 and ferritin were examined using RT-PCR assay. Results showed that, the expression of Hsp90 mRNA was not significantly changed at $15^{\circ}C$. The expression of Hsp90 mRNA was significantly increased at high temperature such as $20^{\circ}C$ and $25^{\circ}C$. Furthermore, Hsp90 mRNA was early increased at $25^{\circ}C$ than $20^{\circ}C$. The ferritin mRNA was similar expression pattern with Hsp90. But, Hsp90 mRNA was more sensitive than ferritin mRNA at high thermal stress. These results indicate that Hsp90 and ferritin mRNAs were involved in the temperature changes response and may be play an important role in mediating the thermal stress in A. japonicas.

• Analytical Science and Technology
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• v.14 no.1
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• pp.8-14
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• 2001

New process to determine $^{90}Sr$ in the environmental samples was established by investigating the existing methods. The environmental samples included soil, milk, seaweed, fishes and clams, pine needles, and marine sediment. Using the developed method combined with fuming nitric acid and ion exchange resin, which could be reduced the treatment step, we could be removed Ca effectively for the determination of $^{90}Sr$. The recovery yield of $^{90}Sr$ in this method was 10% higher than those of using the fuming nitric acid only. This method could be applied to all environmental samples we choose. The content of $^{90}Sr$ in soil was the highest value in the tested environmental samples.

• Journal of the Korean Magnetic Resonance Society
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• v.18 no.1
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• pp.10-14
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• 2014

Hsp90 is a good drug target molecule that is involved in regulating various signaling pathway in normal cell and the role of Hsp90 is highly emphasized especially in cancer cells. Thus, much efforts for discovery and development of Hsp90 inhibitor have been continued and a few Hsp90 inhibitors targeting the N-terminal ATP binding site are being tested in the clinical trials. There are no metabolic signature molecules that can be used to evaluate the effect of Hsp90 inhibition. We previously found a potential C-domain binder named PPC1 that is a synthetic small molecule. Here we report the metabolomics study to find signature metabolites upon treatment of PPC1 compound in lung cancer cell line, A549 and discuss the potentiality of metabolomic approach for evaluation of hit compounds.