• 설비공학논문집
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• 제7권1호
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• pp.63-72
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• 1995

Convective heat transfer in a two-dimensional horizontal and vertical channel with isothermal rectangular beams attached to one adiabatic wall is investigated from the numerical solution of Navier-Stokes and energy equations. The solutions have been obtained for dimensionless beam spacings, S/L=1~4, aspect ratios of beam, H/B=0.25~4, Reynolds numbers, Re=50~1000 and Grashof numbers, $Gr=0{\sim}5{\times}10^4$. The total mean Nusselt number, Nu_T for horizontal and vertical channels shows same value at Gr=0. As Gr increases, Nu_T for horizontal channel increases, but Nu_T for vertical channel shows similar value at S/L=2, H/B=0.25, Re=100. The total mean Nusselt number for horizontal channel is higher than that for vertical channel. As H/B increases, $Nu_T$ for both channel decrease at $Gr=10^4$, Re=100.

• 전자공학회논문지
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• 제52권12호
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• pp.3-9
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• 2015

본 논문에서는 새로운 구조의 모노펄스수신기 동작 절차를 제시하고, 설계 및 제작을 통해 모노펄스 기울기 및 추적정확도 등의 성능을 분석하였다. 제작된 모노펄스수신기의 기울기와 3채널 모노펄스수신기의 기울기가 동일함을 검증하였으며, +0.7~-0.7 범위에서 0.1 RMS 이하의 추적정확도 성능을 확인하였다. 제작된 모노펄스수신기를 적용한 모노펄스시스템은 3채널의 수신기 및 신호처리기를 요구하는 일반적인 3채널 모노펄스시스템에 비해 1채널의 수신기를 요구하고 신호처리가 필요 없으므로 수신부 및 처리부의 구조가 간단하며, 크기, 무게, 비용, 소모전력 측면에서 절감 등의 이점을 갖고 있다. 또한, 수신기의 디텍터에 의해 측정한 합 및 차신호의 동위상 결합전력에서 역위상 결합전력의 차이를 이용하여 모노펄스 추적을 수행하므로 모노펄스 추적절차가 용이하다.

• Journal of Ginseng Research
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• 제37권2호
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• pp.201-209
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• 2013

Ginsenoside, one of the active ingredients of Panax ginseng, has a variety of physiologic and pharmacologic effects. The purpose of this study was to explore the effects of ginsenoside Rd (G-Rd) on melastatin type transient receptor potential 7 (TRPM7) channels with respect to the proliferation and survival of AGS and MCF-7 cells (a gastric and a breast cancer cell line, respectively). AGS and MCF-7 cells were treated with different concentrations of G-Rd, and caspase-3 activities, mitochondrial depolarizations, and sub-G1 fractions were analyzed to determine if cell death occurred by apoptosis. In addition, human embryonic kidney (HEK) 293 cells overexpressing TRPM7 channels were used to confirm the role of TRPM7 channels. G-Rd inhibited the proliferation and survival of AGS and MCF-7 cells and enhanced caspase-3 activity, mitochondrial depolarization, and sub-G1 populations. In addition, G-Rd inhibited TRPM7-like currents in AGS and MCF-7 cells and in TRPM7 channel overexpressing HEK 293 cells, as determined by whole cell voltage-clamp recordings. Furthermore, TRPM7 overexpression in HEK 293 cells promoted G-Rd induced cell death. These findings suggest that G-Rd inhibits the proliferation and survival of gastric and breast cancer cells by inhibiting TRPM7 channel activity.

• Journal of Magnetics
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• 제22권2호
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• pp.238-243
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• 2017

In this research, we report the preliminary results of an insertional type parallel transmission (pTx) array that has 7-elements that are placed in the space above a patient table as a transmit (Tx) coil to give an RF transmission ($B_1{^+}$) field for the body object of a 3 Tesla (T) MRI system. In previous research, we have tried to compare the performances of different coil elements and array geometries for a pTx body image. Based on these results, we attempt to obtain a human image with the proposed pTx array. Through the simulation and experimental results, we introduce a possible structure of multi-channel Tx array and verify the utility of a multi-channel Tx body image using $B_1{^+}$ shimming. The insertional pTx array, combined with a receiver (Rx) array coil, provides an enhanced $B_1{^+}$ field homogeneity in a large ROI image as a result of $B_1{^+}$ shimming applied over the full body size object. Through this research, we hope to determine the usefulness of the proposed insertional type RF coil combination for 3 T body imaging.

• 한국통신학회논문지
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• 제28권7C호
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• pp.678-687
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• 2003

전력 및 대역폭 제한적인 디지털 통신 시스템을 위한 새로운 변복조 기술인 8SQAM(8-state Superposed Quadrature Amplitude Modulation)은 인접하는 두 심볼간에 진폭과 위상이 상관관계를 유지함으로써 부드럽고 연속적인 위상천이와 함께 적은 포락선 변동을 갖는 출력신호를 생성한다. 또한 8SQAM신호는 심볼간 간섭이 없으며 compact한 스펙트럼 특성을 갖는다. 따라서 8SQAM은 기존의 8PSK와 비교하여 비선형 왜곡에 의한 혼변조(IM)와 인접 심볼 간섭(ISI) 그리고 다중채널(SCPC-FDMA) 환경에서의 인접 채널 간섭(ACI) 영향을 적게 받는다. 본 논문에서는 비선형 증폭 다중채널 간섭 환경에서 8SQAM 시스템의 수신 성능을 전산모의 실험을 통해서 분석하였다. 전산모의 실험 결과 8SQAM은 고출력증폭기(HPA)의 Input back-off(IBO)가 1dB이고 채널 간격이 데이터 비트 율의 41.7%(즉, 스펙트럼 효율 =2.40b/s/Hz)일 때, BER=1$\times$$10^{-4}$ 을 유지하기 위해 요구되는 CNR이 $\alpha$= 0.3의 roll-off 값을 갖는 8PSK 보다 2.7dB 우수한 성능을 보였다.

• 대한전자공학회논문지
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• 제22권4호
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• pp.1-7
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• 1985

본 논문에서는, drain 전압과 substrate bias에 종속적인 관계를 갖는 short-channel enhancement-mode IGFET의 threshold전압에 대한 보다 개선된 모델을 제시한다. 특히, 최근에 발표된 몇몇 모델들에 비해. short-channel effect에 의한 correction factor를 정확히 해석함으로써 오차를 충분히 줄일 수 있었으며, 본 모델을 이용하여 계산한 이론값은 약 1μm 정도의 채널 길이를 갖는 device에 대해서도 실험값과 잘 일치한다.

• Biomolecules & Therapeutics
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• 제19권1호
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• pp.33-37
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• 2011

Decursin was purified from Angelica gigas Nakai, and its effects on the human Kv1.5 (hKv1.5) currents were recorded in mouse fibroblasts ($Ltk^-$ cells) by whole-cell patch-clamp technique. Decursin inhibited hKv1.5 current in a concentration-dependent manner, with an $IC_{50}$ value of $2.7\;{\mu}M$ at +60 mV. Decursin accelerated the inactivation kinetics of the hKv1.5 channel, and slowed the deactivation kinetics of the hKv1.5 current, resulting in a tail crossover phenomenon. Also, decursin inhibited the hKv1.5 current in a use-dependent manner. These results strongly suggest that decursin is a kind of open-channel blocker of the hKv1.5 channel.

• The Korean Journal of Physiology and Pharmacology
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• 제7권6호
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• pp.333-339
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• 2003

It has been demonstrated that an unidentified cytosolic factor(s) reduces $K_{ACh}$ channel function. Therefore, this study attempted to elucidate the cytosolic factor. Fresh cytosol isolated from normal heart (FC) depressed the $K_{ACh}$ channel activity, but cytosol isolated from the ischemic hearts (IC) did not modulate the channel function. Electrophorectic analysis revealed that a protein of ${\sim}80 kDa was markedly reduced or even lost in IC. By using peptide sequencing analysis and Western blot, this 80 kDa protein was identified as transferrin (receptor-mediated $Fe^{3+}$ transporter, 76 kDa). Direct application of transferrin (100 nM) to the cytoplasmic side of inside-out patches decreased the open probability ($P_o$, 12.7${\pm}6.4%, n=4) without change in mean open time (${\tau}_o$, $98.5{\pm}1.3$%, n=4). However, the equimolar apotransferrin, which is free of $Fe^{3+}$, had no effect on the channel activity (N*$P_o$, $129.1{\pm}13.5$%, n=3). Directly applied $Fe^{3+}$ (100 nM) showed results similar to those of transferrin (N*$P_o$: $21.1{\pm}3.9$%, n=5). However $Fe^{2+}$ failed to reduce the channel function (N*$P_o$, $106.3{\pm}26.8$%, n=5). Interestingly, trivalent cation La3+ inhibited N*$P_o$ of the channel ($6.1{\pm}3.0$%, n=3). Taken together, these results suggest that $Fe^{3+}$ bound to transferrin can modulate the $K_{ACh}$ channel function by its electrical property as a polyvalent cation.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 추계학술대회
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• pp.1270-1275
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• 2004

Flow condensation heat transfer coefficients(HTCs) of R22 and R134a were measured on horizontal aluminum multi-channel tube. The experimental apparatus was composed of three main parts ; a refrigerant loop, a water loop and a water-ethylene glycol loop. The test section in the refrigerant loop was made of aluminum multi-channel tube of 1.4 mm hydraulic diameter and 0.53 m length. The refrigerant was cooled by passing cold water through an annulus surrounding the test section. The data scan vapor qualities $(0.1{\sim}0.9)$, mass flux ($200{\sim}400$ $kg/m^{2}s$) and heat flux ($7.3{\sim}7.7$ $kW/m^{2}$) at $40{\times}0.2^{\circ}C$ saturation temperature in small hydraulic diameter tube. It was found that some well-known previous correlations were not suitable for multichannel tube. So, It must develop new correlations for multi-channel tubes.

• 한국통신학회논문지
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• 제32권10A호
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• pp.1065-1071
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• 2007

본 논문은 도심 협곡 환경에서 마이크로파 대역 다중안테나 이용기술의 주파수 이용효율 특성을 파악하기 위한 3.7GHz와 8GHz의 MIMO 측정 데이터 및 채널 용량을 분석한 결과를 기술하였다. 채널 측정 데이터는 분당의 3-4층 빌딩 밀집지역에서 실험된 데이터를 이용하였으며, 3.7 GHz와 8 GHz대역 전파특성 파라미터를 추출하여 비교 분석하였다. 다중안테나 사용에 따른 채널용량을 분석한 결과 3.7 GHz와 8 GHz 대역의 $2{\times}2$ 다중안테나 환경에서 9.1 bps/Hz와 5 bps/Hz으로 분석되었으며, $4{\times}4$ 안테나 이용 시 각각 21 bps/Hz와 12.5 bps/Hz로 분석되었다. 이를 통해 실외 도심협곡 환경의 신호 대 잡음비와 커버리지 특성을 고려해 볼 때 3.7 GHz대역의 주파수 전송효율이 8 GHz 보다 우월한 특성을 보임을 확인하였다.