• Natural Product Sciences
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• 제8권4호
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• pp.129-132
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• 2002

The MeOH extract of the twig of Morus alba L. (Moraceae) inhibited strong lipid peroxidation activity. In order to find out active principle from the plant, acivity-guided fractionation was performed and five antioxidant compounds were isolated. Their chemical structures were identified as 6-geranylapigenin (1), 6-geranylnorartocarpetin (2), resveratrol (3), oxyresveratrol (4) and quercetin (5) by physicochemical and spectrometric methods. Compounds 1-5 significantly inhibited lipid peroxidation in rat brain homogenate $(IC_{50}\;values\;of\;3.37,\;3.74,\;0.23,\;0.29\;and\;0.06\; {\mu}M,\;respectively)$.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.377.2-377.2
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• 2002

The MeOH extract of the twig of Marus alba L. (Moraceae) inhibited strong lipid peroxidation activity. Five antioxidative compounds were isolated through activity-guided fractionation. and identified as 6-geranylapigenin (1). 6-geranylnorartocarpetin(2). resveratrol (3). oxyresveratrol (4). quercetin (5) by physicochemical and spectrometric methods. In order to evaluate the antioxidant effect of these compounds. the lipid peroxidation inhibitory activity test were performed. Compounds 1-5 showed greater activity than tocopherol. (omitted)