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Antioxidant Compounds from Twig of Morus alba  

Jin, Wen-Yi (College of Pharmacy, Chungnam National University)
Na, Min-Kyun (College of Pharmacy, Chungnam National University)
An, Ren-Bo (College of Pharmacy, Chungnam National University)
Lee, Hyun-Yong (College of Pharmacy, Chungnam National University)
Bae, Ki-Hwan (College of Pharmacy, Chungnam National University)
Kang, Sam-Sik (Natural Products Research Institute, Seoul National University)
Publication Information
Natural Product Sciences / v.8, no.4, 2002 , pp. 129-132 More about this Journal
Abstract
The MeOH extract of the twig of Morus alba L. (Moraceae) inhibited strong lipid peroxidation activity. In order to find out active principle from the plant, acivity-guided fractionation was performed and five antioxidant compounds were isolated. Their chemical structures were identified as 6-geranylapigenin (1), 6-geranylnorartocarpetin (2), resveratrol (3), oxyresveratrol (4) and quercetin (5) by physicochemical and spectrometric methods. Compounds 1-5 significantly inhibited lipid peroxidation in rat brain homogenate $(IC_{50}\;values\;of\;3.37,\;3.74,\;0.23,\;0.29\;and\;0.06\; {\mu}M,\;respectively)$.
Keywords
Morus alba L.; Moraceae; 6-geranylapigenin; 6-geranylnorartocarpetin; resveratrol; oxyresveratrol; quercetin; lipid peroxidation inhibitory activity;
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Times Cited By KSCI : 1  (Citation Analysis)
Times Cited By SCOPUS : 14
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