• Title/Summary/Keyword: 6-O-Vanillyoxypaeoniflorin

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A New Monoterpene Glycoside and Antibacterial Monoterpene Glycosides from Paeonia suffruticosa

  • An, Ren-Bo;Kim, Hyun-Chul;Lee, Sung-Hee;Jeong, Gil-Saeng;Sohn, Dong-Hwan;Park, Hyun;Kwon, Dong-Yeul;Lee, John-Hwa;Kim, Youn-Chul
    • Archives of Pharmacal Research
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    • v.29 no.10
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    • pp.815-820
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    • 2006
  • Antibacterial activity-guided fractionation of the $CHCl_3-MeOH$ (1:1) extract of Paeonia suffruticosa root bark furnished three monoterpene glycosides, 6-O-vanillyoxypaeoniflorin (1), mudanpioside-H (2), and galloyl-oxypaeoniflorin (3). Of the isolated compounds, compound 1 is a new compound. All isolated compounds showed broad, but moderate, antibacterial activity with minimum inhibitory concentration (MIC) values in the range of 100 to $500\;{\mu}g/mL$ against eighteen pathogenic microorganisms of concern for public health or zoonosis.