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A New Monoterpene Glycoside and Antibacterial Monoterpene Glycosides from Paeonia suffruticosa  

An, Ren-Bo (College of Pharmacy, Wonkwang University,College of Pharmacy, Yanbian University)
Kim, Hyun-Chul (College of Pharmacy, Wonkwang University)
Lee, Sung-Hee (College of Pharmacy, Wonkwang University)
Jeong, Gil-Saeng (College of Pharmacy, Wonkwang University)
Sohn, Dong-Hwan (College of Pharmacy, Wonkwang University)
Park, Hyun (Department of Infection Biology, College of Medicine, Wonkwang University)
Kwon, Dong-Yeul (College of Pharmacy, Wonkwang University)
Lee, John-Hwa (College of Veterinary Medicine and Bio-Safety Research Institute, Chonbuk National University)
Kim, Youn-Chul (College of Pharmacy, Wonkwang University)
Publication Information
Archives of Pharmacal Research / v.29, no.10, 2006 , pp. 815-820 More about this Journal
Abstract
Antibacterial activity-guided fractionation of the $CHCl_3-MeOH$ (1:1) extract of Paeonia suffruticosa root bark furnished three monoterpene glycosides, 6-O-vanillyoxypaeoniflorin (1), mudanpioside-H (2), and galloyl-oxypaeoniflorin (3). Of the isolated compounds, compound 1 is a new compound. All isolated compounds showed broad, but moderate, antibacterial activity with minimum inhibitory concentration (MIC) values in the range of 100 to $500\;{\mu}g/mL$ against eighteen pathogenic microorganisms of concern for public health or zoonosis.
Keywords
Paeonia suffruticosa; 6-O-Vanillyoxypaeoniflorin; Monoterpene glycoside; mudanpioside-H; Galloyl-oxypaeoniflorin; Antibacterial;
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