• Gut and Liver
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• 제12권6호
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• pp.655-663
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• 2018

Background/Aims: The association between metabolic syndrome and colorectal cancer (CRC) has been suggested as one of causes for the increasing incidence of CRC, particularly in younger age groups. The present study examined whether the current age threshold (50 years) for CRC screening in Korea requires modification when considering increased metabolic syndrome. Methods: We analyzed data from the National Health Insurance Corporation database, which covers ~97% of the population in Korea. CRC risk was evaluated with stratification based on age and the presence/absence of relevant metabolic syndrome components (diabetes, dyslipidemia, and hypertension). Results: A total of 51,612,316 subjects enrolled during 2014 to 2015 were analyzed. Among them, 19.3% had diabetes, hypertension, dyslipidemia, or some combination thereof. This population had a higher incidence of CRC than did those without these conditions, and this was more prominent in subjects <40 years of age. The optimal cutoff age for detecting CRC, based on the highest Youden index, was 45 years among individuals without diabetes, dyslipidemia, and hypertension. Individuals with at least one of these components of metabolic syndrome had the highest Youden index at 62 years old, but the value was only 0.2. Resetting the cutoff age from 50 years to 45 years achieved a 6% increase in sensitivity for CRC detection among the total population. Conclusions: Starting CRC screening earlier, namely, at 45 rather than at 50 years of age, may improve secondary prevention of CRC in Korea.

• 대한지역사회영양학회지
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• 제21권6호
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• pp.558-573
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• 2016

Objectives: The purpose of this study was to evaluate the main sources of dietary sodium and potassium intake in Koreans by gender, age and regions. Methods: We used the data from 2010-2012 KNHANES. A total of 20,387 subjects aged 8 years and older were included. Intakes were compared by gender, age (8-18, 19-49 and >50 years) and geographical regions in Korea. Dishes were classified into 28 dish groups based on cooking methods. Statistical analysis was performed by using the SAS 9.3 and SUDAAN 11.0.1 software. Results: The mean sodium intake of Koreans was $4866.5{\pm}35.9mg/day$, which was 2.4 times higher than the adequate intake (AI) of sodium for Koreans. We found that daily sodium intakes were significantly different by age, gender and regions. Men and aged over 50 years had significantly higher sodium intake than women and other age groups. The mean potassium intake in Koreans was $3002.2{\pm}19.4mg/day$ and daily potassium intakes were significantly different by age, gender and regions. Women and age 50 years and over had significantly higher potassium intakes than men and other age groups. The average Na/K ratio was $2.89{\pm}0.01$ and was highest in men and in the age group of 19-49 years. The major sources of dietary sodium were soup and stew, followed by Kimchi, noodles and dumpling, pickled vegetables and seasonings, which represented 63.1 % of total sodium intakes. Soup and stew or Kimchi were the primary sources of dietary sodium intake. The major sources of dietary potassium were cooked rice, followed by soup and stew, Kimchi, fruits and beverages. Conclusions: Sodium and potassium intakes and the major sources of those were significantly different by gender, age groups and regions. Therefore, different approaches based on gender, age and regions are needed to decrease sodium intake and increase potassium intake.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.2285-2289
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• 2016

Background: Epstein-Barr virus (EBV) positive diffuse large B-cell lymphoma (DLBCL) of the elderly is an entity introduced in the latest WHO classification of lymphoid tumors and defined in patients older than 50 years without prior lymphoma or immunodeficiency. However, recently it has also been seen in patients under 50. There is thus debate as to whether these are separate entities. Materials and Methods: In this retrospective study, we analyzed de novo DLBCL admitted to our institute over a period of two years. Clinical data included age, sex, nodal and extranodal presentation. The results of an immunohistochemistry (IHC) panel were also reviewed. IHC findings were mainly used to sub-classify DLBCL as germinal center vs. non germinal center types. IHC for identification of LMP-1 (latent membrane protein) and in situ hybridization for detection of EBV-encoded RNA (EBER) was performed. EBV prevalence, clinical data and IHC findings were compared between patients under and over 50 years of age. Results: Out of 95 DLBCL, 11.6% were EBV positive (7.5% and 14.5% in the young and old groups). We did not find any significant differences in IHC subclasses and clinical data between EBV positive DLBCL (EBV+DLBCL) of young and old groups. Conclusions: EBV+DLBCL are not exclusive to patients older than 50 years. With regard to clinical data as well as IHC subclasses, no differences were evident between EBV+DLBCL of young and old groups. Our suggestion is to eliminate any cut off age for EBV+DLBCL.

• Asian Pacific Journal of Cancer Prevention
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• 제13권6호
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• pp.2695-2698
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• 2012

Introduction: Design and implementation of screening programs in each country must be based on epidemiological data. Despite the relatively high incidence of CRC, there is no nationwide comprehensive program for screening in Iran. This study was designed to investigate national CRC data and help to determine guidelines for screening. Methods: Incidence data used in this study were obtained from Iranian annual of National Cancer Registration report. Age standardized rates (ASR)were calculated using world standard population and were categorized by age, sex, anatomic subsite and morphology of tumor. Data were analyzed using SPSS.V.13 and Open Source Epidemiologic Statistics for Public Health software (OpenEpi v.2.3.1). Results: A quarter of cases were less than 50 years of age. The majority of tumors were detected in the colon. The overall ASR in the four years period was 38.0 per 100000 and was higher for men compared women (P<0.05). Incidence rate of colorectal cancer increased with age. Conclusion: Results of present study indicated that incidence of colorectal cancer is relatively high in Iran. Incidence of CRC in people under 50 years and in rectum were reported higher than other countries that related etiologic factors should be investigate in further studies. According to the increasing of ASR after age 50 years, it seems that onset of screening at age 50 would be appropriate.

• 복식
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• 제60권6호
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• pp.74-88
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• 2010

This study investigates the relevance between the subjective age and clothing shopping orientation by adults women located in the cities of Seoul and Gyeonggi. The results are following. First, subjective age was identified with interest age, look age, and physical age. Customers were segmented into following five subdivisions: young activity group, actual age group, young appearance group, physical aging group and youth-oriented group. When the study examined differences between real age and subjective age, the study could see that they perceived themselves younger four years than real age- 50s: 7 years, 40s: 5 years, the latter half of 30s: 2.7 years and the former half of 30s: 1.7 years. Second, clothing shopping orientation was identified with planned shopping orientation, leisure shopping orientation, loyal shopping orientation, economic shopping orientation and convenient shopping orientation. Customers were segmented into following three subdivisions: shopping low-involved group, loyal leisure group and planned leisure oriented group. Third, interest age was of no relevance to clothing shopping orientation. On the other hand, look age had negative correlation with leisure shopping orientation and convenient shopping orientation and physical age had a negative relationship with leisure shopping orientation and loyal shopping orientation but had positive correlation with economic shopping orientation. Fourth, in clothing purchase, clothing purchase answerers who were younger five years than actual age had the highest frequency. It means that they purchase clothing according to subjective age perceived younger four years on average.

• Journal of Nutrition and Health
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• 제32권8호
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• pp.927-934
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• 1999

Dietary and other factors affecting serum lipid levels of 103 rural women aged 30-76 years were assessed. Data for dietary intakes were obtained by 24-hour recall method. Body weight, height and blood pressure were measured and BMI was calculated from the anthropometric data. Serum samples were collected and analyzed for TG and lipoprotein fractions. Relation of the factors with serum lipid concentration was analyzed by Pearson's correlation coefficient(r). The results were summarized as follows: The weight, hight and BMI of the subjects were 56.8kg, 152.4cm and 24.5k/==, respectively. 31.8% of the subjects under 50 years of age($\leq$49yr group) and 61.0% of the subjects from 50 years up(==50yr group) were classified as hyperlipidemia. Most of the subjects had normal blood pressure but 8.5% were hypertensive. Total food intake of hyperlipidemic subjects was more than those of normal subjects in both age groups. Nutrients intake also tended to be higher in hyperlipidemic subjects of $\geq$50yr group. Intake of some foods like nuts, milk, or meat affected serum lipid profile even though the effects was somewhat different between two age groups. Body weight was positively related with serum TG and VLDL-cholesterol in $\leq$49yr group, and body weight as well as height and BMI affected serum lipid level in $\geq$50yr group. In summarization, it appeared that hyperlipidemia was a serious health problem in rural women. Hypertriglyceridemia due to sharp increase after 50 years old was remarkable and further research should be performed to determine the related factors in the near future.

• Journal of Nutrition and Health
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• 제34권5호
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• pp.568-579
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• 2001

This study was conducted to identify the characteristics of Korean diet in the view of food and food group intakes. The study subjects consisted of preschool children(PC), elementary school children(EC), high school students(HS), college students(CS), and adults over 30 years old living Seoul and the surrounding areas. The subjects over 30 years old were classified to 30-49 years, 50-69 years, and over 70 years. A dietary survey was conducted using 24-hour recall method and data were collected from 2392 subjects. Rice was a major contributor to many nutrients intake because of the amount of consumption. Vegetable oil made great contribution to fat intakes and eggs, squid, and anchovy supplied much cholesterol compared to other foods in all the age groups. Milk was major contributor of fat and cholesterol as well as calcium in younger age group, and seasoning gave much contribution to iron intakes. Mean dietary variety score(DVS) was 32 for EC group and 17 for subjects over 70 years, and tended to decrease along the increasing age. EC group consumed most variable number of foods of all groups but they consumed many junk foods, therefore the MAR value was low despite their high DVS value. Mean dietary diversity score(DDS) of each age group from PC group to subjects over 70 years was 4.34, 4.28, 3.79, 3.89, 3.76, 3.56, and 3.25, respectively. Food group, which was consumed below the minimum amount, was mainly fruits in all the age groups, and many subjects in HS group and over 30 years consumed dairy products below the minimum amount. From these results, age specific nutritional problems were found. PC group and subjects over 50 years seemed to need more diverse food intake than now, EC group did nutrient dense food, and HS group and subjects over 30 years did dairy products. Also, subjects took various nutrients from rice and seasoning contributed to some nutrients intakes. (Korean J Nutrition 34(5) : 568∼579, 2001)

• 대한지역사회영양학회지
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• 제17권4호
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• pp.440-449
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• 2012

This study was carried out to investigate the distribution of body composition, and to analyze its relationship to dietary behaviors and life style. The study subjects were divided into 3 age groups; 30' years (n = 78) 40' years (n = 71) and 50' years (n = 44). The data was collected by physical measurement (Inbody 230) and questionnaires. The rate of disease and general characteristics were higher in the 50 year old group than in the other groups. Average amount of body water, protein, mineral and body fat were 29.0 kg (50.4%), 7.7 kg (13.4%), 2.8 kg (4.8%), 18.7 kg (31.5%), respectively. The rate of menopause was significantly different with increasing age. Menopause was 1.3%, 9.1%, 79.6% by age respectively. Body fat percent was significantly increased and body water decreased with age (p < 0.01). The fat composition was higher and the mineral content was lower in 50' year old group. Dietary behavior scores of 30' year old group was significant lower than in the other two groups (p < 0.001). The means of salty eating, skipping meals, fruit intake and food habits total point were significantly higher in the 50 year old group than in the other groups. There were significant positive correlations between age, BMI, waist hip ratio respectively (p < 0.01). There were significant negative correlations between age and body water, body mineral, skeletal muscle (p < 0.01, p < 0.05, p < 0.01). The results of this study suggested that nutritional management and education for adult women differ by age group.

• 복식문화연구
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• 제15권1호
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• pp.137-151
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• 2007

This study was performed to narrow down the Sizing System for Female Adult's garments(KS K 0051) following age target and body shapes. The study was based on the sizing system and the anthropometric measurements, called Size-Korea, which were surveyed in the years 2003 and 2004. At first, the subjects of the survey were classified into 4 age groups, $18{\sim}24,\;25{\sim}34,\;35{\sim}49\;and\;50{\sim}59$, based on the most significant differences of body sizes. Secondly, the ranges of four key dimensions - height, bust, waist and hip-of normal sizes were identified through analyzing Rohrer index and percentile. The selected sizes within the ranges were grouped by the drop which was the subtraction of bust girth from hip girth. In conclusion, there was the most frequent drop for each age group; 9cm drop for the $18{\sim}24$ years old group, the 6cm drop for the $25{\sim}34$ years old and $35{\sim}49$ years old and 3cm drop for $50{\sim}59$ years old. The upper body garment sizes of the same drop and target ages could be merged to 10 to 12 sizes, which were remarkably smaller than the Female Adult garment sizing system, and further to 2-5 sizes, considering the percentile importance. However, $50{\sim}59$ years old group needed to be analyzed in different ways, because the number of subjects of normal size in the age decreased rapidly, that the normal sizes for them were very limited. In addition, the reference body sizes of each garment size were apparently different when they were compared to each age groups. These basic data for garment size specification could be usefully adapted for the apparel companies' own sizing system according to their age target and body shapes, to achieve efficient production and better fit.

• Asian Pacific Journal of Cancer Prevention
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• 제17권sup3호
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• pp.5-10
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• 2016

Breast cancer, the second cause of cancer-related death after lung cancer and the most common cancer in women after skin cancer, is curable if detected in early stages of clinical presentation. Knowledge as to any age cut-off points which might have significance for prognostic groups is important in screening and treatment planning. Therefore, determining a change-point could improve resource allocation. This study aimed to determine if a change point for survival might exist in the age of breast cancer diagnosis. This study included 568 cases of breast cancer that were registered in Breast Cancer Research Center, Tehran, Iran, during the period 1986-2006 and were followed up to 2012. In the presence of curable cases of breast cancer, a change point in the age of breast cancer diagnosis was estimated using a mixture survival cure model. The data were analyzed using SPSS (versions 20) and R (version 2.15.0) software. The results revealed that a change point in the age of breast cancer diagnosis was at 50 years age. Based on our estimation, 35% of the patients diagnosed with breast cancer at age less than or equal to 50 years of age were cured while the figure was 57% for those diagnosed after 50 years of age. Those in the older age group had better survival compared to their younger counterparts during 12 years of follow up. Our results suggest that it is better to estimate change points in age for cancers which are curable in early stages using survival cure models, and that the cure rate would increase with timely screening for breast cancer.