• Title/Summary/Keyword: 4-period development

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Patent Analysis in the Clinical Diagnosis Sector : Before and After COVID-19 (COVID-19 전후 의료 진단 특허 출원 동향 분석)

  • Han, Yoojin;Park, Sunju
    • Journal of Society of Preventive Korean Medicine
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    • v.26 no.2
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    • pp.25-35
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    • 2022
  • Objectives : This study aims to analyze the patents filed in the clinical diagnosis sector where technologies have been actively developed since the advent of the 4th industrial revolution. Methods : The analysis has been conducted in two ways - the period from 2016 to 2021 and the time points before and after COVID-19 - by visualizing based on the word cloud method. Results : Over two thirds of patents has been filed in the A61B sector (71.8%) and cure, sensor, self diagnosis, control, and breakdown have been observed in the period above. During the overall period (2016~2021), 'ultrasound'(7.5%), 'image'(5.1%), 'skin'(4.0%), 'treatment'(3.4%), and 'artificial intelligence(2.5%)' were the frequently patent applications technologies. In addition, 'ultrasound'(6.2%), 'image'(5.5%), 'skin'(4.0%), 'treatment' (3.7%), and 'portable'(1.7%) appeared most frequently before COVID-19 whereas 'ultrasound(5.5%)', 'artificial intelligence(4.2%)', 'diagnostic device'(1.9%), 'dimentia'(1.6%), and 'diagnostic kit'(1.4%) emerged the most after COVID-19. Conclusion : This study is meaningful in that it showed the technological development trend in the digital diagnosis sector and it was found that the Korean medicine field should contribute to this field more actively in the future.

Performance Appraisal of Total Maximum Daily Loads: Performance on Development/Reduction Plan and Water Quality Status of Unit Watershed (수질오염총량관리제의 성과평가: 개발/삭감계획의 이행실적 및 단위유역의 수질 현황)

  • Park, Jae Hong;Park, Jun Dae;Rhew, Doug Hee;Jung, Dong Il
    • Journal of Korean Society on Water Environment
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    • v.25 no.4
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    • pp.481-493
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    • 2009
  • This study was conducted to performance appraisal of Total Maximum Daily Loads (TMDLs), especially in terms of performance on development & reduction plan and water quality status of unit watershed. Because load allocations for pollution sources were predicted redundantly by uncertainty of prediction, TMDLs master plan has been frequently changed to acquire load allocation for local development. Therefore, It need to be developed more resonable prediction techniques of water pollution sources to preventing the frequent change. It is suggested that the reduction amount have to be distributed properly during the planning period. In other words, it has not to be concentrated on the specific year (especially final year of the planning period). The reason why, if the reduction amount concentrate on the final year of the planning period, allotment loading amount could not be achieved in some cases (e.g., insufficiency of budget, extension of construction duration). If the development plan was developed including uncertain developments, it is necessary to be developed reduction plan considered with them. However, some of the plans in the reduction plan could not be accomplished in some case. Because, it is not considered financial abilities of local governments. Consequently, development plan must be accomplished to avoid uncertain developments, and to consider financial assistance to support the implementation of effective plan. Water quality has been improved in many unit watersheds due to the TMDLs, especially in geum river and yeongsang/seomjin river.

Quality Characteristics and Antioxidant Activity of Oat-added Curd Yogurt (귀리 첨가 호상 요구르트의 저장 중 항산화 활성 및 품질 특성)

  • Lee, Mi Ja;Kim, Hyun Young;Yang, Ji Yeong;Song, Seung-Yeob;Seo, Woo Duck;Choi, June-Yeol
    • The Korean Journal of Food And Nutrition
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    • v.35 no.5
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    • pp.324-331
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    • 2022
  • Recently, consumers' awareness of the importance of the intestinal action of lactic acid bacteria and intestinal microbes is increasing, as well as interest in yogurt. In this study, yogurt was prepared with three mixed strains (lactic acid bacteria combination, Lactobacillus acidophilus, Lactobacillus delbrueckii subsp., and Bulgaricus, Streptococcus thermophilussei, 1:1:1) by adding oats flour, and the quality characteristics of yogurt were investigated, while stored at a storage temperature of 4℃ for 12 days. According to the storage period, the control as wel as the oat yogurt showed slight decrease in pH, and no significant change in acidity. Sugar content slightly increased. and brightness decreased, in the control and the oat yogurt. Visible cell numbers increased during storage, and decreased on the 12th day. Viscosity in the oat yogurt was 7,580 cP, which was approximately eight times higher than that of the control group, and decreased gradually according to the storage period. Antioxidant activity (DPPH) was approximately two times higher in the oat-added yogurt, and slightly increased with the storage period, decreased on the 12th day of storage, and β-glucan was detected only in oat-added yogurt.

Development of CMMS for the real-time CBMS (CMMS(Computerized Maintenance Management System)의 실 시간적인 CBMS(Condition Based Maintenance System) 연구)

  • 박주식;박재현;강경식;이광배
    • Journal of the Korea Safety Management & Science
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    • v.2 no.4
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    • pp.1-8
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    • 2000
  • Equipment and machine of industrial plant are give effect to mechanical-stress of many working-stop or long time operating. Therefore, to be old and decrepit of every king of equipment. As long time operating equipment period into increase conservation and of repair equipment time is efficacious necessity of utility factor gradually that of productivity of diminution and complete equipment expense of increase. Conservation at special skill working and necessity is that will effectually and complete a period prevention management diagnosis can conservation point at issues at in advance.

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Conflict in the Shadow of Conflict

  • BANG, SE HOON;KIM, JAESOO
    • KDI Journal of Economic Policy
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    • v.38 no.4
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    • pp.95-114
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    • 2016
  • We study how an advantage given to an interim winner in sequential conflicts characterizes dynamic competition between players and influences their payoffs. As the intensity of competition during each period is negatively correlated, perfect security is not necessarily desirable for contending parties. We present results which are widely applicable to various types of dynamic competition, where competition in each period is linked to the interim winner's relative advantage. Policy implications are also discussed in a variety of areas, and several extensions are explored.

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Effects of irradiation periods on the Lettuce Growth (광원 조사기간이 상추생육에 미치는 영향)

  • Kim, Dong-Eok;Kim, Bong-Soo;Kim, Hyun-Bae;Yoon, Yong-Cheol;Kim, Chi-Ho;Kim, Hyeon-Tae
    • Korean Journal of Agricultural Science
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    • v.39 no.4
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    • pp.459-466
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    • 2012
  • The objective of this study is to observe growth pattern of grand rapids(lettuce) according to different dexperimental conditions for minimizing its growth period such as composition of nutrient, irradiation time of light source and cultivation mode. The culture of water spray type using seeds of grand rapids was performed during growth period of total 50 days. Experimental conditions consist of five compositions of nutrient (PW 0.5 mS/cm, PW 1.0 mS/cm, PY 0.5 mS/cm, PY 1.0 mS/cm, PW 2.0 mS/cm) and three irradiation times of light source (12h(on) / 12h(off), 18h(on) / 06h(off), 24h(on) / 00h(off)). Illumination was adjusted to ratio of 7:1:1 of red, blue and white color, respectively. Indoor environmental condition for cultivating grand rapids is as follows: temperature (19-$22^{\circ}C$), relative humidity (60-70%) and carbon dioxide (1,000-1,200 ppm). The data were obtained from five iteration tests. The maximum growth level was observed in the experimental condition of 18 hr(on) / 06 hr(off) and PY 1 mS/cm for 1st week of cultivation period, 24 hr(on) / 00 hr(off) and PY 1mS/cm for 2nd week of cultivation period, and 24 hr(on) / 00hr(off) and PW 1 mS/cm for 3rd week of cultivation period, respectively. On the contrary, the minimum growth level was observed in the experimental condition of 18 hr(on) / 06 hr(off) and PW 0.5 mS/cm for 1st week of cultivation period, 12 hr(on) / 12 hr(off) and PW 0.5 mS/cm for 2nd week of cultivation period, and 12 hr(on) / 12 hr(off) and PY 0.5 mS/cm for 3rd week of cultivation period, respectively. Based on the results obtained from this study, it is concluded that the growth level of grand rapids varied with different irradiation time of light source and composition ratio of nutrient according to cultivation period.

Development of the Mathematical Model to Calculate Groundwater Ages Using Tritium and Analysis on Groundwater Flow Times around the Samkwang Mine (트리튬을 이용한 지하수 연대측정 수학모델 개발 및 삼광광산 주변 지하수 유동시간 분석)

  • 김계남;구자공;김천수
    • Journal of the Korean Society of Groundwater Environment
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    • v.2 no.2
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    • pp.72-77
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    • 1995
  • Flow times of the groundwater in the gneiss near Samkwang mine in Korea were estimated through the development of a mathematical model, the field hydraulic tests, and the analysis of tritium concentration of the groundwater and rainfall sampled in the study positions. Results of this study we as follows: (1) The mathematical model to calculate the age of groundwater was developed considering the tritium concentrations of rainfall precipitated in the studied area for period 1961 to 1993. (2) The ages of the groundwater in the tunnel 44, 92, 102, and 205 m below the surface were estimated at 2, 0, 4.0, 4.5, and 9.0 years, respectively. These results were verified by the data on the tritium concentrations of the groundwater in the tunnel for period 1991 to 1993.

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Treatment of pigs with enrofloxacin via different oral dosage forms - environmental contaminations and resistance development of Escherichia coli

  • Janssen, Paula;Barton, Gesine;Kietzmann, Manfred;Meissner, Jessica
    • Journal of Veterinary Science
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    • v.23 no.2
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    • pp.23.1-23.15
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    • 2022
  • Background: Antibacterial agents play important roles in the treatment of bacterial infections. However, the development of antimicrobial resistance (AMR) and carry-over of substances into the environment are several problems arising during oral treatment of bacterial infections. We assessed AMR development in commensal Escherichia coli (E. coli) in enrofloxacin treated and untreated animals. In addition, we examined fluoroquinolone in the plasma and urine of treated and untreated animals, and in sedimentation dust and aerosol. Methods: In each trial, six pigs were treated with enrofloxacin via powder, granulate or pellet forms in two time periods (days 1-5 and 22-26). Four pigs served as untreated controls. The minimum inhibitory concentration (MIC) was determined to evaluate AMR development. Analysis of enro- and ciprofloxacin was performed with high performance liquid chromatography. Results: Non-wildtype E. coli (MIC > 0.125 ㎍/mL) was detected in the pellet treated group after the first treatment period, whereas in the other groups, non-wildtype isolates were found after the second treatment period. E. coli with MIC > 4 ㎍/mL was found in only the pellet trial. Untreated animals showed similar susceptibility shifts several days later. Bioavailability differed among the treatment forms (granulate > pellet > powder). Enro- and ciprofloxacin were detected in aerosols and sedimentation dust (granulate, powder > pellet). Conclusions: This study indicates that the kind of the oral dosage form of antibiotics affects environmental contamination and AMR development in commensal E. coli in treated and untreated pigs.

Temperature-dependent Development Model of Hawaiian Beet Webworm Spoladea recurvalis Fabricius (Lepidoptera: Pyraustinae) (흰띠명나방의 온도발육 모형)

  • Lee, Sang-Ku;Kim, Ju;Cheong, Seong-Soo;Kim, Yeon-Kook;Lee, Sang-Guei;Hwang, Chang-Yeon
    • Korean journal of applied entomology
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    • v.52 no.1
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    • pp.5-12
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    • 2013
  • The Hawaiian beet webworm (Spoladea recurvalis) is one of the serious insect pests found on red beet (Beta vulgaris var. conditiva) in Korea. The study was conducted to investigate the development period of S. recurvalis at various constant temperatures, 15.0, 17.5, 20.0, 22.5, 25.0, 27.5, 30.0, 32.5 and $35.0^{\circ}C$, with $65{\pm}5%$ RH and a photoperiod of 16L:8D. The developmental period from egg to pre-adult was 51.0 days at $17.5^{\circ}C$ and 14.6 days at $35.0^{\circ}C$. The developmental period of S. recurvalis was decreased with increasing temperature. The relationship between the developmental rate and temperature was fitted well by linear regression analysis ($R^2{\geq}0.87$). The lower developmental threshold and effective accumulative temperature of the total immature stage were $10.4^{\circ}C$ and 384.7 degree days, respectively. The nonlinear relationship between the temperature and developmental rate was well described by the Lactin model. The relationship between the cumulative frequency and normalized distributions of the developmental period for each life stage were fitted to the Weibull function with $R^2=0.63{\sim}0.87$.

Effect of Acidulant Treatment on the Quality and Storage Period of Topokkidduck (산미료 단독 처리가 떡볶이 떡의 저장기간 및 품질에 미치는 영향)

  • Ra, Ha-Na;Cho, Yong-Sik;Hwang, Young;Jang, Hyun-Wook;Kim, Kyung-Mi
    • Journal of the Korean Society of Food Culture
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    • v.35 no.6
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    • pp.613-618
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    • 2020
  • This study evaluated the effects of acidulant treatment on the quality and storage period of Topokkidduck. Two samples of Topokkidduck were prepared, one soaked in 10% acidulant (10SAT) and the other without soaking in the acidulant (NSAT). During the storage period, the two samples were tested for presence of microorganisms (aerobic bacteria, E.coli, and mold) and physicochemical properties (color value, texture profile analysis (TPA)). The 10SAT could be stored for 49 days without detection of E.coli and a mold level of 1.0 log CFU/g. NSAT could be stored for only 21 days. NSAT had an aerobic count of 2.27 log CFU/g as early as 7 days, and E.coli was detected at 21 days at a level of 4.15 log CFU/g. The presence of E.coli is not permitted according to the Ministry of Food and Drug Safety (MFDS). The hardness of the 10SAT increased during the storage period but to a much lesser extent compared to the NSAT. Thus the preparation of Topokkidduck by soaking in the acidulant controlled microbial growth for up to 49 days which is a much longer period compared to the control. Also, Topokkidduck soaked in the acidulant had a softer texture than the control during the storage period.