• Journal of Veterinary Clinics
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• v.32 no.3
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• pp.235-238
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• 2015

This study aimed to investigate the epidemiology of canine ophthalmic diseases in Seoul, Korea using data for new canine patients examined from January 2009 through December 2013 at an ophthalmic referral center (WooSung Animal Medical Center, Seoul). The study included 1253 dogs with an average age of 7.93 years (SD, 4.06). Shih Tzu (29.4%) was the most common breed, followed by Maltese, Yorkshire Terrier, Cocker Spaniel, and toy Poodle (P < 0.01). Lens diseases (28.3%) were the most common, followed by eyelid, corneal, retinal, and glaucomatous diseases (P < 0.01). Lens, eyelid, retinal, nasolacrimal, uveal, vitreous, and neuro-ophthalmic diseases more frequently showed a bilateral occurrence (P < 0.01) than a unilateral occurrence. In the Shih Tzu breed, corneal disease was the most frequent, followed by lens, eyelid, retinal, and glaucomatous diseases. The most frequent diseases in the Maltese breed were lens, eyelid, retinal, and corneal diseases. In the Yorkshire Terrier, Cocker Spaniel, and toy Poodle breeds, lens disease was the most common (P < 0.01). The most frequent ophthalmic patients belonged to small breeds such as Shih Tzu, Maltese, and Yorkshire Terrier. Moreover, the most common ophthalmic diseases were not traumatic diseases, but breed-inherited diseases such as lens diseases.

• Journal of Korean Biological Nursing Science
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• v.25 no.4
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• pp.243-253
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• 2023

Purpose: This study conducted a concept analysis to clarify the meaning of anxiety in hospitalized patients with infectious diseases who have been placed in isolation. Methods: This study used Walker and Avant's process of concept analysis. Results: Anxiety in hospitalized patients with infectious diseases who have been placed in isolation can be defined by the following attributes: 1) fear, 2) guilt, 3) isolation, 4) discrimination, 5) frustration, 6) shame, and 7) uncertainty. The antecedents of anxiety were as follows: 1) a lack of information about infectious diseases, 2) restrictions of movement, 3) blockage of the social support system, 4) helplessness, and 5) negative biases. The consequences of anxiety were 1) internalized stigma, 2) loss of confidence, 3) lack of social activities and avoidance, 4) insomnia, 5) poor quality of life. Conclusion: The definition and attributes of anxiety identified in this study can be applied to enhance the understanding of anxiety in hospitalized patients with infectious diseases who have been placed in isolation. Systematic suppose should also be provided to reduce anxiety in these patients.

• Korean Journal of Veterinary Service
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• v.46 no.4
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• pp.283-291
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• 2023

Brucellosis and tuberculosis are major infectious and contagious bacterial diseases in cattle. These diseases are malicious diseases that must be inspected at the slaughterhouse of cattle in accordance with the practice of quarantine in Korea. Furthermore, both diseases lead to abortion, reproductive disorder, and calf disease, causing major difficulty in the breeding of Korean Native cattle (Hanwoo), a representative industrial animal currently being raised in Korea. Co-infections of these diseases intensify clinical symptoms such as abortion and have a particularly significant effect on increasing mortality. Thus, serological tests were performed in Hanwoo, to establish the association of co-infection between brucellosis and tuberculosis in cattle. ELISA and PCR tests were conducted on blood samples collected from a total of 102 cattle in Jeonnam province, Korea, to detect brucellosis and tuberculosis infections. The PCR results revealed that 41 samples tested positive for Brucella abortus (B. abortus) infection (40.20%), and 5 samples tested positive for Mycobacterium bovis (M. bovis) (4.90%) infection confirmed by PCR. Notably, 9.76% (4/41) of the cattle infected with brucellosis also tested positive for tuberculosis. In conclusion, this study highlights the co-infection of brucellosis and tuberculosis among Hanwoo cattle in Jeonnam province, which is expected to contribute to our understanding of disease transmission, pathogenicity, the establishment of future prevention strategies.

• Tuberculosis and Respiratory Diseases
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• v.81 no.4
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• pp.351-351
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• 2018

• Tuberculosis and Respiratory Diseases
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• v.78 no.4
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• pp.473-473
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• 2015

• 한국유가공학회:학술대회논문집
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• 2005.06a
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• pp.1-12
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• 2005

Chronic diseases such as cancer, cardiovascular diseases, are the leading cause of death and disability in Korea since 1970 due to lifestyle change introduced by urbanization & industrialization. The type of cancer and cardiovascular diseases changes as lifestyle becomes westernized. These diseases account for 4 of every 10 deaths and affect the quality of lift of Koreans. Although chronic diseases are among the most common and costly healthy problems, they are also preventable. Adopting healthy behaviors such as quitting smoking, being physically active, eating right with moderate alcohol drinking, and maintaining healthy weight can prevent or control the effect of these diseases.

• Journal of agricultural medicine and community health
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• v.15 no.1
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• pp.41-48
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• 1990

In order to find out the status of health care of the old aged people (age of 65 and over) in a rural area, a study was carried out, through analyzing the data of health care clinic for 207 old aged people with geriatric diseases, and of questionnired survey for 84 old aged people with geriatric diseases in a rural community. Su Dong-Myun. Nam Yang Zu-Gun, Kyung Gi-Do, Korea, during the year of 1989. The following results were obtained. 1) The composition rate of population of age of 65 and over was 9.8% in total, and sex-specific composition rate was 9.3% in male and 10.4% in female. 2) Utilization rate of health care clinic for old aged people with geriatric diseases was the highest rate with 37.9%, through individual letters at the first time, and showed gradually decreasing tendency afterward. 3) In the means of utilization advices to health care clinic for the old aged people. the individual letters(37.9%) at the first time were more effective than public information of the old aged hall or/and Myun office(18.4%). 4) In opinion on utilization of health subcenter-health care clinic for the old aged people "will utilize"(59.5%) was the highest and "do not know"(26.2%) "be difficult to utilize" (9.5%) and "will not utilize"(4.8%) were in the next order. 5) Out of 84 respondents, the old aged people With geriatric diseases, 73.8%(about three-fourths) of them answered "their diseases to the aggravated" (29.8%) "not to be changed"(25.0%) and "to be unknown"(19.0%), and the others(26.2% of them) "to be changed for the better". 6) Out of 62 respondents(the old aged people), answered their geriatric diseases not to be changed for the better, "no curative effect" was the highest with 43.5% of them. "could not know" (33.9%), "would not treat"(19.4%) and "could not be treated"(4.8%) were in decreasing order. 7) The old aged people, responded their diseases to be changed for the better, answered that they(patients) should make themselves(68.2%) responsible for basic effort of health care. However the old aged people responded their diseases not to be changed for the better answered that they should impute the responsibility of basic effort for health care to medical facilities or other conditions(63.0%). 8) In the reason of failure that the old aged people responded their geriatric diseases not to have curative effect, mis-control of regular habits of daily life was the highest(57.1%), and failure of taking selected medicine steadily(28.6%), and abuse of medicines(14.3%) were in decreasing order. 9) The reason order of being changed for the better that the old aged people responded their diseases to have curative effect, was keeping and control of regular habits of daily life (46.7%), taking selected medicines steadily(33.3%) and others (20.2%) respectively. 10) The courses of geriatric diseases itself are so chronic, duplicate and uncertain, and the old aged people activities for disease control are so slow, various and uncertain that continuous health education in home or/and community unit must be essential factors for effective geriatric health care.

• The Journal of Internal Korean Medicine
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• v.29 no.3
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• pp.629-640
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• 2008

Objective : The purpose of this study was to investigate the neuroprotective effect of Jukryuk on 4-vessel occlusion(4-VO) and middle cerebral artery (MCA) ischemia. Method : After administration of Jukryuk, we compared the Jukryuk-treated group, the control, and the sham groups, in view of several points as follows 1) We evaluated the damage characterized by coagulative cell change of pyramidal neurons and pronounced gliosis in each group 2) We counted the number of normal pyramidal shapes after ischemia in each group 3) Immunohistochemistry (cyclooxygenase-2) 4) In focal ischemic injury model, we measured the volume of ischemic area Results : In this experiment, the effect of Jukryuk was determined to be protecting neuron cell shape, reducing the number of neuron cells damaged by ischemia and the volume of the ischemic area. In immunohistochemistry, Jukryuk reduced cyclooxygenase-2 expression Conclusions : According to this study, Jukryuk can protect neuron cells from injury by cerebrovascular ischemia.

• Journal of Sasang Constitutional Medicine
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• v.18 no.2
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• pp.1-14
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• 2006

1. Objectives This study is purposed to classify deficiency syndrome(虛證) and Excess syndrome(實證) of chief lung-disorder diseases. 2. Methods It was researched on the comparative and literal study about the relation to Yeong-Chu Gyeong-maek Chapter (${\ulcorner}$靈樞 經脈編${\Ircorner}$) and Dongui-Bogam (${\ulcorner}$東醫寶鑑${\Ircorner}$) and Dongui-Susebowon (${\ulcorner}$東醫壽世保元${\Ircorner}$) in chief lung-disorder symptoms or diseases. 3. Results and Conclusions (1) The chief lung-disorder diseases of Yeong-Chu Gyeong-maek Chapter (${\ulcorner}$靈樞 經脈編${\Ircorner}$), Dongui-Bogam (${\ulcorner}$東醫寶鑑${\Ircorner}$) and Dongui-Susebowon (${\ulcorner}$東醫壽世保元${\Ircorner}$) are asthma(喘), coughing(咳), fullness in the chest(胸滿), sweating symptoms(汗出), cold-heat symptoms(寒熱), dysphoria(煩躁) and sneezing. (2) Asthma symptom(喘) was shown to Soeumin's 4 exterior deficiency diseases, Taeumin's 1 exterior deficiency disease and 1 interior excess disease, and Soyangin's 1 interior excess disease. (3) Coughing symptom(咳) was shown to Soeumin's 1 extrerior deficiency disease and Taeumin's 1 interior excess disease. (4) Fullness in the chest(胸滿) was shown co Soyangin's 4 exterior excess diseases. (5) Sweating symptoms(汗出) was shown to Soeumin's 10 exterior deficiency diseases, Taeumins's 1 exterior deficiency disease, and Soyangin's 1 exterior defecieny disease. (6) Cold-heat symptoms(寒熱) was shown to Soyangin's 4 exterior excess diseases. (7) Dysphoria(煩躁) was shown co Soeumin's 1 exterior deficiency disease and 8 interior deficiency diseases, Taeumin's 1 interior excess disease, and Soyangin's 4 exterior excess and interior excess diseases. (8) Sneezing symptom was shown to Taeumin's 1 exterior excess disease.

• International Journal of Stem Cells
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• v.16 no.2
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• pp.180-190
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• 2023

Background and Objectives: Regenerative endodontic procedures (REPs) are a research hotspot in the endodontic field. One of the biggest problems of REPs is that it is difficult to realize regeneration of pulp-dentin complex and functional reconstruction. The reason is still not clear. We hypothesize that the migration may be different in different dental stem cells. Periodontal ligament stem cells (PDLSCs) may migrate faster than stem cells of apical papilla (SCAPs), differentiating into cementum-like tissue, bone-like tissue and periodontal ligament-like tissue and, finally affecting the outcomes of REPs. Hence, this study aimed to explore the mechanism that regulates the migration of PDLSCs. Methods and Results: After isolating and culturing PDLSCs and SCAPs from human third molars, we compared the migration of PDLSCs and SCAPs. Then we investigated the role of SDF-1𝛼-CXCR4/CXCR7 axis in PDLSC migration. We further investigated the impact of Porphyromonas gingivalis (P. gingivalis) lipopolysaccharide (LPS) on PDLSC migration and the potential mechanism. PDLSCs showed better migration under both noninflammatory and inflammatory conditions than SCAPs. SDF-1𝛼 can promote the migration of PDLSCs by elevating the expression of CXCR4 and CXCR7, increasing the interaction between them, promoting expression of 𝛽-arrestin1 and activating the ERK signaling pathway. P. gingivalis LPS can promote the migration of PDLSCs toward SDF-1𝛼 through increasing the expression of CXCR4 via the NF-𝜅B signaling pathway, promoting the expression of 𝛽-arrestin1, and activating the ERK signaling pathway. Conclusions: This study helped elucidate the potential reason for the difficulty in forming pulp-dentin complex.