• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• 제17권3호
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• pp.272-279
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• 2006

In this paper, we evaluate the performance of frame synchronization words of pilot bit patterns which are used for the channel estimation and frame synchronization confirmation in W-CDMA(Wide band Code Division Multiple Access) system. W-CDMA system also uses compressed mode to make measurements from another frequency without a full dual receiver terminal. It is confirmed by using computer simulation that the proposed frame synchronization words also maintain the frame synchronization property in the compressed mode by using the complementary mapping relationship of preferred pair ROC(Receiver Operating Characteristic) curves with probability of detection and false alarm are used to analized the performance of the proposed frame synchronization words by using the various detection metrics such as LLRT(Log Likelyhood Ratio Test), GLRT(Generalied Likelyhood Ratio Test), soft and hard correlation tests in AWGN and Rayleigh fading channels. It is expected that the research results fer the performance of pilot bit patterns of this paper can be useful reference for the design and implementation of frame synchronization in 3rd generation W-CDMA system.

• Journal of Ginseng Research
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• 제31권3호
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• pp.159-174
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• 2007

Pharmacology of Korean Red ginseng gives us unique possibility to develop new class of antiepileptic drugs today and to improve one's biological activity. The chemical structures of ginsenosides (GS) have some principal differences from well-known antiepileptic new generation drugs. The antiepileptic effect of GS was also demonstrated in all models of epilepsy in rats (young and adult), which have studied, in all models of epilepsy including status epilepticus (SE), induced by lithium - pilocarpine. In our experiments in rats new evidences on protective effects were exerted as a result of premedication by GS. Pre-treatment of several GS could induce decrease of the seizures severity and brain structural damage (by MRI), neuronal degeneration in hippocampus. Wave nature of severity of motor seizures during convulsive SE was observed during lithium-pilocarpine model of SE in rats (the first increase of seizures was 30 min after the beginning of SE and the second - 90 min after. The efficacy of treatment on SE by ginsenoside as expected was observed after no less 3 weeks by daily GS i.p. administration. It is blocked SE or significantly decrease the severity of seizures during SE. The implication of presented data is that combination of ginsenosides from Korean Red ginseng and ginseng cell culture Dan25 that could be applied for prevention of epileptical status development. However, a development of optimal ratio of different ginsenosides $(Rb_1$ Rc, Rg, Rf,) should consummate in the new antiepileptic drug development.

• Journal of Communications and Networks
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• 제13권4호
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• pp.345-359
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• 2011

Decode-and-forward relaying is a promising enhancement to existing radio access networks and is already standardized in 3rd generation partnership project (3GPP) as a part of long term evolution (LTE)-Advanced Release 10. Two inband operation modes of relay nodes are supported, namely type 1 and type lb. Relay nodes promise to offer considerable gain for system capacity or coverage, depending on the deployment prioritization, in a cost-efficient way. Yet, in order to fully exploit the benefits of relaying, the inter-cell interference which is increased due to the presence of relay nodes should be limited. Moreover, large differences in the received power levels from different users should be avoided. The goal is to keep the receiver dynamic range low in order to retain the orthogonality of the single carrier-frequency division multiple access system. In this paper, an evaluation of the relay based heterogeneous deployment within the LTE-Advanced uplink framework is carried out by applying the standardized LTE Release 8 power control scheme both at evolved node B and relay nodes. In order to enhance the overall system performance, different power control optimization strategies are proposed for 3GPP urban and suburban scenarios. A comparison between type 1 and type 1b relay nodes is as well presented to study the effect of the relaying overhead on the system performance in inband relay deployments. Comprehensive system level simulations show that the power control is a crucial means to increase the cell edge and system capacities, to mitigate inter-cell interference and to adjust the receiver dynamic range for both relay node types.

• Journal of the Korea Society of Computer and Information
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• 제15권12호
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• pp.57-66
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• 2010

In this paper, we propose the reliability constrained resource allocation scheduling algorithm in cellular network for uplink transmission, where uplink transmission is supported via packet switching schemes without the dedicated uplink circuit links. We evaluate the performance of the proposed algorithm, and compared with the conventional works to identify the pros and cons. The proposed uplink scheduling algorithm is to satisfy the constraints requirements of the MTC services which is considered as the core technology for future mobile wireless networks. It is different to conventional works which target to maximize the link capacity. The proposed algorithm provides reliable uplink transmission independent to the location and the quality of the wireless link of the mobile terminal. Based on the performance evaluation results, we conclude that the proposed method provides enhanced reliability performance than conventional works.

• Journal of Ginseng Research
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• 제48권2호
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• pp.211-219
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• 2024

Background: Recently, plant-derived exosome-like nanoparticles (PDENs) have been isolated, and active research was focusing on understanding their properties and functions. In this study, the characteristics and molecular properties of ginseng root-derived exosome-like nanoparticles (GrDENs) were examined in terms of skin protection. Methods: HPLC-MS protocols were used to analyze the ginsenoside contents in GrDENs. To investigate the beneficial effect of GrDENs on skin, HaCaT cells were pre-treated with GrDENs (0-2 × 10⁹ particles/mL), and followed by UVB irradiation or H₂O₂ exposure. In addition, the antioxidant activity of GrDENs was measured using a fluorescence microscope or flow cytometry. Finally, molecular mechanisms were examined with immunoblotting analysis. Results: GrDENs contained detectable levels of ginsenosides (Re, Rg1, Rb1, Rf, Rg2 (S), Gyp17, Rd, C-Mc1, C-O, and F2). In UVB-irradiated HaCaT cells, GrDENs protected cells from death and reduced ROS production. GrDENs downregulated the mRNA expression of proapoptotic genes, including BAX, caspase-1, -3, -6, -7, and -8 and the ratio of cleaved caspase-8, -9, and -3 in a dose-dependent manner. In addition, GrDENs reduced the mRNA levels of aging-related genes (MMP2 and 3), proinflammatory genes (COX-2 and IL-6), and cellular senescence biomarker p21, possibly by suppressing activator protein-1 signaling. Conclusions: This study demonstrates the protective effects of GrDENs against skin damage caused by UV and oxidative stress, providing new insights into beneficial uses of ginseng. In particular, our results suggest GrDENs as a potential active ingredient in cosmeceuticals to promote skin health.

• Journal of the Korean Institute of Landscape Architecture
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• 제47권2호
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• pp.49-58
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• 2019

There have been studies on the satisfaction, preference, and post occupancy evaluation of urban parks in order to reflect users' preferences and activities, suggesting directions for future park planning and management. Despite using questionnaires that are proven to be affective to get users' opinions directly, there haven been limitations in understanding the latest changes in park use through questionnaires. This study seeks to address the possibility of utilizing the thirdgeneration SNS data, Instagram and Google, to compare behavior patterns and trends in park activities. Instagram keywords and photos representing user's feelings with a specific park name were collected. We also examined reviews, peak time, and popular time zones regarding selected parks through Google. This study tries to analyze users' behaviors, emerging activities, and satisfaction using SNS data. The findings are as follows. People using park near residential areas tend to enjoy programs being operated in indoor facilities and to like to use picnic places. In an adjacent park of commercial areas, eating in the park and extended areas beyond the park boundaries is found to be one of the popular park activities. Programs using open spaces and indoor facilities were active as well. Han River Park as a detached park type offers a popular venue for excercises and scenery appreciation. We also identified companionship characteristics of different park types from texts and photos, and extracted keywords of feelings and reviews about parks posted in $3^{rd}$ generation SNS. SNS data can provide basis to grasp behavioral patterns and satisfaction factors, and changes of park activities in real time. SNS data also can be used to set future directions in park planning and management in accordance with new technologies and policies.

• Journal of Food Hygiene and Safety
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• 제38권4호
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• pp.193-201
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• 2023

Antimicrobials in human medicine are classified by The World Health Organization (WHO) into three groups: critically important antimicrobials (CIA), highly important antimicrobials (HIA), and important antimicrobials (IA). CIA are antibiotic classes that satisfy two main criteria: that they are the sole or the only available limited therapeutic option to effectively treat severe bacterial infections in humans (Criterion 1), and infections where bacteria are transmitted to humans from non-human sources or have the potential to acquire resistance genes from non-human sources (Criterion 2). WHO emphasizes the need for cautious and responsible use of the CIA to mitigate risk and safeguard human health. Specific antimicrobials within the CIA with a high priority for management are reclassified as "highest priority critically important antimicrobials (HP-CIA)" and include the 3^rd generation of cephalosporins and the next generation of macrolides, quinolones, glycopeptides, and polymyxins. The CIA list is the scientific basis for risk assessment and risk management policies that warrant using antimicrobials to reduce antimicrobial resistance in several countries. In addition, the CIA list ensures food safety in the food industry, including for the popular food chain companies McDonald's and KFC. The continuous update of the CIA list reflects the advancement in research and emerging future challenges. Thus, active and deliberate evaluation of antimicrobial resistance and the construction of a list that reflects the specific circumstances of a country are essential to safeguarding food security.

• Korean Journal of Remote Sensing
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• 제36권5_1호
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• pp.847-860
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• 2020

The 2-pass DInSAR (Differential Interferometric SAR) processing steps for DEM generation consist of the co-registration of SAR image pair, interferogram generation, phase unwrapping, calculation of DEM errors, and geocoding, etc. It requires complicated steps, and the accuracy of data processing at each step affects the performance of the finally generated DEM. In this study, we developed an improved method for enhancing the performance of the DEM generation method based on the 2-pass DInSAR technique of TanDEM-X bistatic SAR images was developed. The developed DEM generation method is a method that can significantly reduce both the DEM error in the unwrapped phase image and that may occur during geocoding step. The performance analysis of the developed algorithm was performed by comparing the vertical accuracy (Root Mean Square Error, RMSE) between the existing method and the newly proposed method using the ground control point (GCP) generated from GPS survey. The vertical accuracy of the DInSAR-based DEM generated without correction for the unwrapped phase error and geocoding error is 39.617 m. However, the vertical accuracy of the DEM generated through the proposed method is 2.346 m. It was confirmed that the DEM accuracy was improved through the proposed correction method. Through the proposed 2-pass DInSAR-based DEM generation method, the SRTM DEM error observed by DInSAR was compensated for the SRTM 30 m DEM (vertical accuracy 5.567 m) used as a reference. Through this, it was possible to finally create a DEM with improved spatial resolution of about 5 times and vertical accuracy of about 2.4 times. In addition, the spatial resolution of the DEM generated through the proposed method was matched with the SRTM 30 m DEM and the TanDEM-X 90m DEM, and the vertical accuracy was compared. As a result, it was confirmed that the vertical accuracy was improved by about 1.7 and 1.6 times, respectively, and more accurate DEM generation was possible with the proposed method. If the method derived in this study is used to continuously update the DEM for regions with frequent morphological changes, it will be possible to update the DEM effectively in a short time at low cost.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• 제14권5호
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• pp.489-498
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• 2003

Recently to introduce new services of ultra-high speed wireless access and systems beyond the 3rd generation mobile communication, 5 GHz band has been highly interested. As a way of getting the required frequency, it is considered that microwave relay bands below 6 GHz, which shows a slow decrease in demand and less cost-effectiveness, should be moved to other bands above 6 GHz. In this paper, as a tool for analyzing microwave link design and its service quality, the outage prediction based upon Vigants & Barnett＇s model is reviewed. To show outage and availability calculation, simulations are performed for the operating 4 GHz radio sites, and some results and features regarding frequency movement to 6.7 as well as 8 GHz are also discussed in terms of diversity techniques, bit error rate, and availability As the results, it is confirmed that only the diversity techniques of space or space and frequency can satisfy the annual objective of availability irrespective of frequency movement.

• Journal of Environmental Health Sciences
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• 제43권4호
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• pp.298-306
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• 2017

Objectives: Since 1998, the Korea National Health and Nutrition Examination Survey (KNHANES) has been conducted in order to investigate the health and nutritional status of Koreans. The food intake data of individuals in the KNHANES has also been utilized as source dataset for risk assessment of chemicals via food. To improve the reliability of intake estimation and prevent missing data for less-responded foods, the structure of integrated long-standing datasets is significant. However, it is difficult to merge multi-year survey datasets due to ineffective cleaning processes for handling extensive numbers of codes for each food item along with changes in dietary habits over time. Therefore, this study aims at 1) cleaning the process of abnormal data 2) generation of integrated long-standing raw data, and 3) contributing to the production of consistent dietary exposure factors. Methods: Codebooks, the guideline book, and raw intake data from KNHANES V and VI were used for analysis. The violation of the primary key constraint and the $1^{st}-3rd$ normal form in relational database theory were tested for the codebook and the structure of the raw data, respectively. Afterwards, the cleaning process was executed for the raw data by using these integrated codes. Results: Duplication of key records and abnormality in table structures were observed. However, after adjusting according to the suggested method above, the codes were corrected and integrated codes were newly created. Finally, we were able to clean the raw data provided by respondents to the KNHANES survey. Conclusion: The results of this study will contribute to the integration of the multi-year datasets and help improve the data production system by clarifying, testing, and verifying the primary key, integrity of the code, and primitive data structure according to the database normalization theory in the national health data.