• 한국운동역학회지
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• 제16권3호
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• pp.149-163
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• 2006

The purpose of this study was to compare the lower extremity's joint and segment coupling patterns between forward and backward running in subjects who were twelve healthy males. Three-dimensional kinematic data were collected with Qualisys system while subjects ran to forward and backward. The thigh internal/external rotation and tibia internal/external rotation, thigh flexion/extension and tibia flexion/extension, tibia internal/external rotation and foot inversion/eversion, knee internal/external rotation and ankle inversion/eversion, knee flexion/extension and ankle inversion/eversion, knee flexion/extension and ankle flexion/extension, and knee flexion/extension and tibia internal/external rotation coupling patterns were determined using a vector coding technique. The comparison for each coupling between forward and backward running were conducted using a dependent, two-tailed t-test at a significant level of .05 for the mean of each of five stride regions, midstance(1l-30%), toe-off(31-50%), swing acceleration(51-70%), swing deceleration(71-90), and heel-strike(91-10%), respectively. 1. The knee flexion/extension and ankle flexion/extension coupling pattern of both foreward and backward running over the stride was converged on a complete coordination. However, the ankle flexion/extension to knee flexion/extension was relatively greater at heel-strike in backward running compared with forward running. At the swing deceleration, backward running was dominantly led by the ankle flexion/extension, but forward running done by the knee flexion/extension. 2. The knee flexion/extension and ankle inversion/eversion coupling pattern for both running was also converged on a complete coordination. At the mid-stance. the ankle movement in the frontal plane was large during forward running, but the knee movement in the sagital plane was large during backward running and vice versa at the swing deceleration. 3. The knee flexion/extension and tibia internal/external rotation coupling while forward and backward run was also centered on the angle of 45 degrees, which indicate a complete coordination. However, tibia internal/external rotation dominated the knee flexion/extension at heel strike phase in forward running and vice versa in backward running. It was diametrically opposed to the swing deceleration for each running. 4. Both running was governed by the ankle movement in the frontal plane across the stride cycle within the knee internal/external rotation and tibia internal/external rotation. The knee internal/external rotation of backward running was greater than that of forward running at the swing deceleration. 5. The tibia internal/external rotation in coupling between the tibia internal/external rotation and foot inversion/eversion was relatively great compared with the foot inversion/eversion over a stride for both running. At heel strike, the tibia internal/external rotation of backward running was shown greater than that of forward(p<.05). 6. The thigh internal/external rotation took the lead for both running in the thigh internal/external rotation and tibia internal/external rotation coupling. In comparison of phase, the thigh internal/external rotation movement at the swing acceleration phase in backward running worked greater in comparison with forward running(p<.05). However, it was greater at the swing deceleration in forward running(p<.05). 7. With the exception of the swing deceleration phase in forward running, the tibia flexion/extension surpassed the thigh flexion/extension across the stride cycle in both running. Analysis of the specific stride phases revealed the forward running had greater tibia flexion/extension movement at the heel strike than backward running(p<.05). In addition, the thigh flexion/extension and tibia flexion/extension coupling displayed almost coordination at the heel strike phase in backward running. On the other hand the thigh flexion/extension of forward running at the swing deceleration phase was greater than the tibia flexion/extension, but it was opposite from backward running. In summary, coupling which were the knee flexion/extension and ankle flexion/extension, the knee flexion/extension and ankle inversion/eversion, the knee internal/external rotation and ankle inversion/eversion, the tibia internal/external rotation and foot inversion/eversion, the thigh internal/external rotation and tibia internal/external rotation, and the thigh flexion/extension and tibia flexion/extension patterns were most similar across the strike cycle in both running, but it showed that coupling patterns in the specific stride phases were different from average point of view between two running types.

• 한국균학회지
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• 제13권3호
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• pp.169-177
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• 1985

느타리버섯Pleurotus ostreatus 및 여름느타리버섯Pleurotus sajor-caju의 원형질체(原形質體)는 감자배지(培地)(PSA) 및 버섯 완전배지(完全培地) (MCM)에 cellophan 반투석막(半透析膜)을 피복(被覆)하여 배양(培養)한 균사체(菌絲體)에서 $2.4{\time}l0^6{\sim}3.5{\time}10^7$ 으로 많이 나출(裸出)되었다. 버섯 완전배지(完全培地)에 4일간(日間) 배양(培養)한 균사체(菌絲體)를 pH가 6.0인 인산(燐酸) 완충용액(緩衝溶液)에 세포벽(細胞壁) 분해효소(分解酵素)인 Novozym 234를 5 mg/ml 농도(濃度)로 용해(溶解)한 효소용액(酵素溶液)에 4시간(時間) 처리(處理)하였을 때 원형질체(原形質體)의 나출수(裸出數)가 가장 많았다. 이들 균주(菌株)의 원형질체(原形質體) 나출(裸出) 시(時) 삼투압 조절제(調節劑)로는 0.6 M sucrose와 0.6 M $MgSO_4$가 가장 적합(適合)하였다. 한편 원형질체(原形質體)의 재생(再生) 시(時)에는 삼투압 조절제(調節劑)로 0.6 M sucrose와 0.6M KCl를 사용(使用)하였을 때 높은 재생율(再生率)을 보였다. 원형질체(原形質體)는 재생용(再生用) 배지(培地)에 접종(接種)한 후 0.75% agar 배지(培地)를 피복(被覆)하였을 때 재생율(再生率)이 향상(向上)되었으며, 이때 300 ppm ampicillin 을 0.75% agar 배지(培地)에 혼합(混合)하여 처리(處理)한 결과(結果) 세균(細菌)의 오염(汚染)을 방지(防止)할 수 있었다. 이들 균주(菌株)의 원형질체(原形質體)는 정상적(正常的)인 균사체(菌絲體)로 환원(還元)되었으며 균사체(菌絲體)는 정상적(正常的)으로 생장(生長)하여 자실체(子實體)와 담자포자(擔子胞子)를 형성(形成)하였다.$1.6{\times}10^{-6}M$로 1 mM ouabain에 영향을 받는 K-pNPPase 활성 및 산소 소모량을 50% 억제하는 농도보다 ouabain은 약 5배 vanadate는 약 15배 정도 낮았다. 이상의 결과로 미루어 가토 신피질 절편에서 측정한 K-pNPPase활성은 $Na^+-K^+$교환 점프의 활성을 나타내는 좋은 지표가 될 수 있으며 특히 세포막을 통한 물질 이동이나 세포의 기능에 대한 영향과 Na-K-ATPase활성에 대한 영향을 동시에 보고자 할 때는 microsome에서 측정한 Na-K-ATPase활성보다 더 이상적이라고 사료된다.>의 dimer 상태로 존재하거나 혹은 $(\alpha\beta)_2$의 monomer에 glycolytic enzymes과 같은 다른 enzymes이 붙어 functional한 구조를 이루고 있는 것이 아닌가 사료된다. 또한 실헐성적은 이러한 dimeric association 혹은 heterocomplex association은 ghost를 만드는 과정에서나 strophanthidin의 처치로 부서질 수 있음을 암시하고 있다.ctor의 길이는 각선수군(各選手群)이 비선수(非選手)보다 낮은 경향(傾向) 나타냈으며, 특(特)히 horizontal plane에서 투척(投擲), 도약(跳躍), 단거리(短距離) 및 야구선수(野球選手)들이 비선수군(非選手群)보다 유의(有意)하게 낮았다. QRS와 T vector의 길이는 선수군(選手群)과 비선수군간(非選手群間)에 차이(差異)가 없었고, 야구선수(野球選手)만이 frontal plane에서 QRS vector의 길이가 비선수군(非選手群)보다 높았다. 이상(以上)의 결과(結果)를 종합(綜合)해 보면 각종목(各種目) 운동선수군(運動選手群) 전반(全般)은 비선수(非選手)보다 유의(有意)

• 한국초지조사료학회지
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• 제12권3호
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• pp.3-12
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• 1992

캐나다에서 화본과와 두과목초 및 사료작물은 가축사양에 있어서 주된 에너지 공급원이다 캐나다에 는 약 1,100만 ha의 개량초지와 조사료 생산은 가능하지만 환경조건이 다소 불량한 방대한 면적의 아직 개발되지 않은 3,000만 ha가 넘는 일반초지가 있다. 캐나다는 약 1,240만우의 육우와 약 150만두 의 젖소를 가지고 있다.캐나다 남부지역에서는 짧은 생육기간이 초지농업을 제한한다. 겨울은 길며, 대부분 지역은 저온, 결벙, 해벙 및 질병 등으로 사초의 월동은 큰 피해를 입고 있다 따라서 적응력 높은 품종의 개발은 양호한 초생유지를 위해 펼수적이며, 특히 생육기간이 짧은 불량 환경지대에서 그러하다. 건물생산은 초여름의 높은 생육에 비해 늦여름과 가을의 낮은 건물축적 양상으로 계절성을 나타낸다. 이러한 불균형적 생산형태를 극복하고 방목기간을 효과적으로 연장시키기 위해서는 혁신적인 관리 기술과 재생력이 우수한 품종개발이 필요하다. 초지의 생산성증대는 가축사육에 있어서 생산비를 절감 시키고 경쟁력을 갖추기 위한 중요한 부문을 차지한다. 유용한 기술의 적용은 초지의 생산성을 증진시키고 사내에서의 저장사료 사양의존도를 낮추며 소규모 농가들을 경제적으로 유리하게 해준다. 수확과 저장 및 사양과정에서 영양분 손실의 방지는 생산효율을 높이는데 펼수적이다. 사일리지 조제시에 도 생산비 절감과 생력관리기숭 개발은 조사료 위주 낙농엽의 생산효율을 높이고 순수익을 높이는데 큰 역할을 하고 있다. 축산업은 저지방이나 저콜레스테롤 식풍 같은 소비자의 가호성을 충족시키는 데에 지속적인 관심을 기울여야 하며, 연구와 교육 및 농민지도에 있어서 많은 어려움은 있으나 협력과 공동연구를 확대시켜 조사료 위주의 축산업을 발전시켜야 한다

• 대한인간공학회지
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• 제36권2호
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• pp.145-156
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• 2017

Objective: This study aims to compare the usability of the adaptive touch design method with that of the height adjustable design method that are applied to the Korean QWERTY keyboard and Naratgul keyboard on smartphones, examine the results, and present practical implications. Background: Smartphone manufacturers have failed to satisfy every user with their uniform touch keyboard designs that do not consider the high use rates of keypad use. In reality, touch keyboard designing customized for every individual is impossible, but there need to be researches on was to improve usability by having touch areas changed automatically depending on user behaviors or having users adjust the keyboard height depending on their hand size. Method: As for the design methods, an object group was given smartphones with the adaptive touch design method and the other group those with the height adjustable design method. As they entered the same characters in the smartphones, typing error rates and text input speed were measured and the average values were compared. 35 individuals who would frequently use smartphones in daily life participated in the experiment. The group variable was the type of touch keyboards, and the test variables were typing error rates and text input speed, for which a T-test was implemented. Results: As for the QWERTY keyboard, the significant improvement effect was verified as the typing error rate of the adaptive touch design method was 4.21% but that of the height adjustable design method was 3.28% although there was no significant difference in terms of text input speed. As for the Naratgul keyboard, in contrast, the typing error rate of the adaptive touch design method was 2.5% while that of the height adjustable design method was 1.48%, which indicates a measure of improvement, but the effect was not significant. On the other hand, the text input speed per minute was improved as much as 22.2%, which is significant. Conclusion: First, the Korean touch keyboard usability of the adaptive touch design method and that of the height adjustable design method, when applied to Model A of Company L, showed significant difference from each other. Second, the height adjustable design method was applied to the QWERTY keyboard, the typing error rate was improved significantly. This indicates that as the keyboard height was raised, the number of buttons within the range of fingering decreased, decreasing the touch bias was reduced. Third, the height adjustable design method was applied to the Naratgul keyboard, the text input speed was improved. Application: When the QWERTY keyboard was applied to a smartphone as small as 5.5inch or less, it is highly probably that the height adjustable design method decreases the typing error rate. It may be considered to develop additional UX functions to make the keyboard font larger or give users the option to adjust button intervals in utilization of the SW advantages of the height adjustable design method.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제15권4호
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• pp.239-252
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• 1993

This study was done to analyze phonetic dysfunction and the effect of orthognathic surgery to phonation in the patients of mandibular prognathism. 20 persons were chosen as normal group and 20 patients of mandibular prognathism as abnormal for this study. 5 vowel sounds-'ㅏ(a)', 'ㅔ(e)', 'ㅣ(i)', 'ㅗ(o)', 'ㅜ(u)' and 14 consonant sounds-'ㄱ(g)', "ㄴ(n), 'ㄷ(d)', 'ㄹ(l)', 'ㅁ(m)', 'ㅂ(b)', 'ㅅ(s)', 'ㅇ(ng)', 'ㅈ(j)', 'ㅊ(ch)', 'ㅋ(k)', 'ㅌ(t)', 'ㅍ(p)', 'ㅎ(h)', were checked. We recorded these sounds in the period of preopration, postop. 12 months, postop. 24 months. A Formant ratio and a length of consonant time were studied with discriminant analysis. As a result of the study, the following conclusion were gained. 1. As a result of the analysis on vowel dysfunction patiensts of mandibular prognathism, more than 80% of men patients showed the dysfunction in prelingual sound 'ㅔ(e)' and 'ㅣ(i)'. More than 70% of women patients showed the dysfunction in all vowel. 2. One year later from the orthognathic surgery, men patients showed a marked improvement in 'ㅏ(a)'. The next were 'ㅗ(o)', 'ㅜ(u)' and 'ㅣ(i)'. Women patients showed a marked improvement in 'ㅜ(u)'. 3. Two year later from the orthognathic surgery, men patients showed a marked improvement in prelingual sound 'ㅔ(e)' and postlingual sound 'ㅗ(o)'. Women patients showed a marked improvement in 'ㅏ(a)'. More than 20% of patients showed the phonetic improvement compared with the condition of the postop. 12 months. 4. As a result of the analysis on consonant dysfunction patient of mandibular prognathism. more than 80% of men patients showed the dysfunction in lingual sound 'ㅅ(s)'. Most women patients showed the dysfunction in labial sound 'ㅁ(m)' and lingual sound 'ㄴ(n)'. More than 50% of patients showed the dysfunction in labial sound and lingual sound. 5. One year later from the orthognathic surgery. men patients showed a complete improvement in hard palatal sound 'ㅈ(j)'. The next were labial sound 'ㅂ(b)', lingual sound 'ㅅ(s)', soft palatal sound 'ㄱ(g)' and 'ㅋ(k)'. Women patients showed a marked improvement in soft palatal sound 'ㅇ(ng)' and 'ㄱ(g)'. 6. Two year later from the orthognathic surgery, all patients showed remarkable improvement in consonant sounds. except for labial sound 'ㅁ(m)', 'ㅍ(p)' and lingual sound 'ㄴ(n)'. The improvement ratio was increased as the time was going on compared with the condition of postop 12 months.

• 한국정보과학회논문지:소프트웨어및응용
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• 제31권3호
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• pp.317-331
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• 2004

최근 몇 년간 소프트웨어 에이전트가 소프트웨어 공학의 새로운 추상화 단위로서 연구되고 있다 자율성, 적응성, 협력성 등의 속성을 갖는 에이전트는 특히 분산 시스템, 오픈 시스템, 복잡한 시스템 등의 영역에서 시스템을 구성하는 새로운 추상화 단위로서 이해되고 있다. 그러나 에이전트에 관한 개념과 특성에 관한 연구가 꾸준히 진행되고 있음에도 불구하고, 에이전트 패러다임을 위한 프로그래밍 언어의 실용화는 요원한 상태이다. 이는 에이전트가 갖는 속성이 문제 영역별로 매우 다양해서 이러한 모든 속성을 공통으로 만족시키는 구현 방법에 대한 공통된 의견이 도출되지 못하고 있기 때문이다. 이러한 현실에서 프로그래밍 언어보다 한 단계 상위 계층에 존재하는 프레임워크를 통한 에이전트 개발은 보다 현실적인 대안으로 받아들여지고 있다. 그러나 에이전트 프레임워크를 개발하기 위한 많은 기술들은 개발자간에 공유되고 있지 않아서 동일한 시행착오를 반복하는 경우가 많다. 본 논문에서는 이러한 문제의 해결책으로 객체지향 기술에서 주로 사용되는 패턴 언어를 사용함으로써, 에이전트 프레임워크 개발의 경험과 지식을 개발자간에 공유하고자 한다. 본 논문은 반응적 에이전트 프레임워크의 개발을 위한 패턴 언어를 제안하고 ATAM(1)에 기반 한 검증의 절차를 거쳤다. 이러한 간접 경험의 증가는 반복해서 발생하는 시행착오를 감소시킴으로써 개발자들이 보다 본질적인 문제에 집중할 수 있도록 도와준다. 이는 결국 고품질의 에이전트 프레임워크 개발에 기여할 것으로 기대된다.

• 한국조리학회지
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• 제20권1호
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• pp.178-188
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• 2014

제주에서 육성된 참다래(한라골드)의 식품 소재화를 위한 방안으로 과육에 고화방지제를 첨가한 분말형 시제품을 제조하였다. 즉, 참다래 과육 페이스트 100%(대조구), 참다래 과육 페이스트 95%+polydextrose 5%, 참다래 과육 페이스트 95%+dextrin 5% 등 3개 시료를 제조한 다음, 동결건조 후 분말화한 각 시제품에 대하여 품질특성을 조사하였다. 참다래 분말 수율은 고화방지제 첨가구가 대조구에 비해 유의적으로 높았다. 수분함량, 산도, 총페놀 함량은 고화방지제 첨가구가 대조구에 비해 유의적으로 낮았다. 비타민C 함량은 고화방지제 첨가구가 대조구에 비해 유의적으로 높은 반면, 고화방지제 첨가구 간에는 차이가 없었다. 유리당(fructose, glucose, total sugar) 및 유기산(oxalic acid, lactic acid, total organic acid)의 함량은 고화방지제 첨가구간에 차이가 없었다. 전반적으로 색도는 모든 시험군에서 높은 L값과 낮은 a값을 나타내었으며, 고화방지제 종류에 따른 갈변도의 차이는 나타나지 않았다. 과육 분말의 용해도(59.57~64.84%)및 팽윤력은 시료간에 유의적인 차이가 없었으나, 시간에 따른 흡습성은 고화방지제 첨가구가 대조구에 비하여 유의적으로 낮음을 보였다. 위의 결과로부터 고화방지제 첨가(5% 수준) 과육 분말은 무첨가 과육분말에 비하여 비타민C의 유지율이 높고, 수분함량이 낮고, 시간에 따른 흡습성이 낮아 우수한 분말 품질 특성을 보였다.

• 한국한의학연구원논문집
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• 제13권1호통권19호
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• pp.129-138
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• 2007

Background : Recently a discussion about Qi including a study about the effect or the theory of acupuncture is getting prevailing in various angles. In most of studies about acupuncture stimulus, 'Filiform acupuncture'(毫鍼) is used. A study about Nine kinds of acupuncture(九鍼), except 'Filiform acupuncture'(毫鍼) has not been reported yet, and there is no study about using a special acupuncture made for controling Qi either. Objectives : 'DONG CHU CHIM' can be used for patients who are scared of a pain because it is a medical Qikong tool and non-invasive stimulus one. To assess a effect of Qikong operation using 'DONG CHU CHIM' objectively, we stimulated non-invasive to Sobu point of 30 normal adults using 'DONG CHU CHIM' and examined the result in the basis of high confirmed and repetitive HRV which is a functional assessment method of the autonomic nervous system. Method : This study has been proceeded in three periods. Total was 35min : 10min for the former and latter period of acupuncture stimulus, l5min for the acupuncture stimulus period. For each period, we measured 5min of 3 times(Stage I, II, III). Result : Comparing the changes of HRV during pre-stimulation and post-stimulation, HRT was significantly reduced, LOGTP, LOGVLF, LOGLF, LF/HF were significantly increased and SDNN, LOGHF were generally increased but did not show any significant changes. So we think that the stimulus of 'DONG CHU CHIM' affects on the sympathetic system and parasympathetic system, it activates the autonomic nervous system, and it makes the inequality of the sympathetic and parasympathetic nerve to be equal status. Conclusions : We can conclude that the non-invasive stimulus of 'DONG CHU CHIM' can affect significantly to the autonomic nervous system. So it can be used in clinic as a tool of Qikong operation, and it can be also used to weak patients or children because it doesn't give a lot of pain like 'Filiform acupuncture'(毫鍼) compared to invasive stimulus. By the basis of this study, more studies about the effect of 'DONG CHE CHIM' should be done in the future.

• KSBB Journal
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• 제31권4호
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• pp.277-283
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• 2016

In this system, rice cells were genetically modified to express human cytotoxic T-lymphocyte antigen 4-immunoglobulin (hCTLA4Ig) using RAmy3D promoter induced by sugar depletion. Even though the target protein fused with signal sequence peptide, plant cell wall can be a barrier against secretion of recombinant proteins. Therefore, hCTLA4Ig can be trapped inside cell wall or remained in intracellular space. In this study, to enhance the secretion of hCTLA4Ig from cytoplasm and cell walls into the medium, permeabilizing agents, such as dimethyl sulfoxide (DMSO), Triton X-100 and Tween 20, were applied in transgenic rice cell cultures. When 0.5% (v/v) of DMSO was added in sugar-free medium, intracellullar hCTLA4Ig was increased, on the other hand, the secreted extracellular hCTLA4Ig was lower than that of control. DMSO did not give permeable effects on transgenic rice cell cultures. And Triton X-100 was toxic to rice cells and also did not give enhancing permeability of cells. When 0.05% (v/v) Tween 20 was added in rice cell cultures, however, intracellular hCTLA4Ig was lower than that of control cultures. And the maximum 44.76 mg/L hCTLA4Ig was produced for 10 days after induction, which was 1.4-fold increase compared to that of control cultures. Especially, Tween 20 at 0.05% (v/v) showed the positive effect on the secretion of hCTLA4Ig though the decrease of intracellular hCTLA4Ig. Also, Tween 20 as a non-toxic surfactant did not affect the cell growth, cell viability and protease activity. In conclusion, secretion of hCTLA4Ig could be increased by enhancing permeability of cells regardless of the cell growth, cell viability and protease activity.

• Asian-Australasian Journal of Animal Sciences
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• 제28권1호
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• pp.86-94
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• 2015

This experiment was conducted to evaluate the chemical composition and amino acid (AA) digestibility of sunflower seed meal (SFSM) and to use this data to develop prediction equations for estimating AA digestibility for growing pigs. Ten SFSM were collected from five provinces in China. Twelve barrows ($38.8{\pm}4.6kg$), fitted with ileal T-cannula were allotted into two $6{\times}6$ Latin square designs. Each of six experimental periods comprised a 5-d adaption period followed by a 2-d collection of ileal digesta. The ten test diets contained 50% SFSM as the sole source of AA. Another nitrogen-free diet was used to measure the basal endogenous losses of crude protein (CP) and AA. Chromic oxide (0.3%) was used as an inert marker in each diet. There was considerable variation (CV>10%) among the ten SFSM in chemical composition (dry matter [DM]). The concentration of CP and ether extract (EE) ranged from 29.33% to 39.09% and 0.88% to 11.33%, respectively. Crude fibre (CF), neutral detergent fibre and acid detergent fibre ranged from 21.46% to 36.42%, 38.15% to 55.40%, and 24.59% to 37.34%, respectively. There was variation among the ten SFSM in apparent ileal digestibility (AID) and standardized ileal digestibility (SID) for lysine and threonine, which ranged from 63.16 to 79.21 and 55.19% to 72.04% for AID and 67.03% to 82.07% and 61.97% to 77.01% for SID, respectively. The variation in CP and methionine ranged from 60.13% to 74.72% and 74.79% to 88.60% for AID and 66.70% to 79.31% and 77.16% to 90.27% for SID, respectively. Methionine was a good indicator to predict AA digestibility. These results indicate that conventional chemical composition of SFSM was variable (CV>10%) among the ten SFSM (DM). The results of AID, SID and prediction equations could be used to evaluate the digestibility of SFSM in growing pigs.