• The Journal of the Acoustical Society of Korea
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• v.19 no.2
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• pp.33-39
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• 2000

We have studied to obtain the frequency characteristics of the Surface Acoustic Wave(SAW) bandpass filter, having low shape factor, it's interdigital transducer(IDT) was formed on the 35° Y-cut X-propagation Quartz substrate and was evaporated by Aluminium. And then, we performed computer-simulation by a simulator. And, we can design that the apodization weighted type IDT as an input transducer of the filter and the withdrawal weighted type IDT as an output transducer of the filter from the results of our computer-simulation. Also, we have employed that the number of pairs of the input and output IDT are 2200 pairs and 1000pairs, respectively and used the Kaiser-Bessel window function in order to minimize the effect of ripple. And, while the width and the space of IDT's finger are 6㎛ m and 5.75㎛, respectively and we could obtain the resonable results when the IDT thickness was 6000Å in consideration of the ratio of SAW's wavelength, and IDT aperture is 2mm. Frequency response of the fabricated SAW bandpass filter has the property that the center frequency is about 70MHz, shape factor is less than 1.3, bandwidth at the 1.5dB is probably 1.3MHz, out-band attenuation is almost -45dB, insertion loss is 19dB and ripple in the width of bandpass is 1dB approximately. Therefore, these frequency characteristics of the fabricated SAW bandpass filter are agreed well with the designed values.

• Journal of Life Science
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• v.33 no.2
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• pp.149-157
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• 2023

Transforming growth factor-β (TGF-β) is a multifunctional cytokine that affects not only the survival and growth of cancer cells but also the activity of immune cells. Although it has been generally accepted that cancer cell-derived TGF-β could promote the survival and growth of early cancer cells and have immunosuppressive roles, it has been known that TGF-β has differential effects according to the type or stage of cancer cells. Therefore, it is hard to clearly define its role in cancer progression and immune responses. This study investigated the effects of TGF-β signaling on the expression of five NKG2D ligands and the NK cell-mediated anticancer immune response in the primary colon cancer cell line KM12C and its two metastatic cell lines, KM12SM and KM12L4A. At the surface protein level, exogenous TGF-β decreased the expression of MICA, MICB, ULBP1, and ULBP2, and galunisertib increased the expression of MICA, MIAB, ULBP1, ULBP2, and ULBP3 in KM12C. However, KM12SM and KM12L4A showed no significant changes in the expression of NKG2DLs after treatment with TGF-β or galunisertib. TGF-β signaling inhibition via galunisertib improved the NK cell-mediated anticancer immune response against KM12C but did not show a significant response to KM12SM and KM12L4A. Therefore, the suppression of TGF-β signaling could improve the NK cell-mediated anticancer immune response against KM12C. However, an increase in NKG2DLs expression and an enhanced NK cell-mediated cancer immune response is hard to expect due to the alteration of TGF-β signaling in KM12SM and KM12L4A.

• Journal of the Korean Geotechnical Society
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• v.19 no.3
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• pp.65-74
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• 2003

The dragload on pile groups in consolidating ground was investigated based on a numerical analysis. The case of a single pile and subsequently the response of groups were analyzed by 2D and 3D finite element studies. Conventional continuum elements and special slip elements were used in the analyses for comparison. Based on a limited parametric study, it is shown that dragload for a single pile and group effect are normally overestimated by continuum analyses, compared with the predictions by the slip analyses. The group effect was examined from the slip analysis by considering various factors such as pile configurations, surface loading, interface friction coefficient, and axial loading on piles. An examplary analysis and one previous experimental observation of dragload and group effects were back-analysed. The case histories demonstrated that the slip analysis might predict a better estimate of dragload and group effect compared to the no-slip continuum analysis.

• Fire Science and Engineering
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• v.20 no.3 s.63
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• pp.29-34
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• 2006

The flash and fire point are the most important combustible properties used to determine the potential for the fire and explosion hazards of flammable material. The flash point is defined as the lowest temperature at which a flammable liquid gives off sufficient vapor to form an ignitable mixture with air near its surface or within a vessel. The fire point is the temperature of the flammable liquid at which there will be flaming combustion, sustained 5 seconds in response to the pilot flame. In this study, the flash points and fire points were measured to present raw data of the flammable risk assessment for acids, using Pensky-Martens Closed Cup(C.C.) apparatus (ASTM-D93) and Tag Open-cup (O.C.) apparatus(ASTM D 1310-86). The measured fire points were compared with the estimated values based on 1.11 times stoichiometric concentration. The values calculated by the proposed equation were in good agreement with measured values.

• Journal of Korean Tunnelling and Underground Space Association
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• v.3 no.4
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• pp.3-15
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• 2001

Generally, it has been noted that underground structures have a consistent record of suffering much less damage than surface facilities during earthquakes; but it is still necessary to illustrate the dynamic response of tunnel structures subject to earthquake loadings and to provide the appropriate method for the seismic analysis of underground tunnel structures since many types of underground structures have been and will be constructed in countries situated within seismic zones. In this study, first, seismic analyses for underground tunnel structures are performed by using quasistatic analysis method and dynamic analysis method. Second, seismic analyses in tunnel portals are performed by using above methods. The results of seismic analyses for the tunnel structure show that the tunnel structure conforms to ground deformation and that seismic design by using the quasi-static analysis method is more conservative than that by using the dynamic analysis. The results of the dynamic FEM analysis for the tunnel structure show that the simplified 2-D FEM analysis using a sine wave rather than the 3-D FEM analysis can be adopted for seismic analysis. Finally, the results of the dynamic FEM analysis in tunnel portals show that the force acting on the lining is largest near to the tunnel portal when an earthquake wave propagates parallel to tunnel axis.

• Journal of Electrochemical Science and Technology
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• v.7 no.1
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• pp.68-75
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• 2016

In this study a new, simple, precise, accurate and economic electrochemical method was developed and validated for the voltammetric determination of zolpidem (ZP) using disposable pencil graphite (PG) electrode. The anodic oxidation of ZP on the surface of the PG electrode was examined in a britton robinson (BR) buffer. Square wave and cyclic voltammetry were used as electrochemical techniques in the potential range of 0-1.2 V in the pH 8 BR buffer. In cyclic voltammetry studies, the diffusion coefficient of ZP oxidation was found to be 3.6×10^-6 cm² s^-1. On the other hand, the ZP has shown a well-defined irreversible anodic peak at 0.98 V in the square wave voltammetry mode. The PG electrode, primarily being graphite which has a large active surface area gives rise to increasing peak current with respect to ZP electrooxidation. PG electrode showed an electrocatalytic effect in anodic oxidation of ZP. A linear relationship between catalytic current response and ZP concentration was obtained over a concentration range of 10-30 μM with R.S.D. values ranging from 0.29-3.89. Limits of detection and quantitation were found to be 1 and 3 μM, respectively. Finally, the PG electrode was successfully used to determine ZP in standard and tablet dosage forms with a mean recovery of 100.69 %.

• Journal of Magnetics
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• v.21 no.3
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• pp.387-392
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• 2016

Lower flux leakage designs have become important in the development of microspeakers used in thin and miniaturized mobile phones. We propose four methods to reduce the flux leakage of the magnetic circuit in a microspeaker. Optimization was performed based on the proposed approach by using the response surface method. Electromagnetic analyses were conducted using the finite element method. Experimental results are in good agreement with the simulated results obtained in one degree-of-freedom analysis from 100 to 5 kHz. Both the simulated and experimental results confirm that one of the proposed methods is much more effective in reducing flux leakage than the other methods. In the optimized method, compared with a default approach, the average radial flux density in the air gap decreased only by 5.5%, the maximum flux leakage was reduced by 28.6%, and the acoustic performance at primary resonance decreased by 0.45 dB, which gap is indiscernible to the human ear.

• Geomechanics and Engineering
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• v.36 no.3
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• pp.277-293
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• 2024

Shored Mechanically Stabilized Earth (SMSE) walls are types of soil retaining structures that increase soil stability under static and dynamic loads. The damage caused by an earthquake can be determined by evaluating the probabilistic seismic response of SMSE walls. This study aimed to assess the seismic performance of SMSE walls and provide fragility curves for evaluating failure levels. The generated fragility curves can help to improve the seismic performance of these walls through assessing and controlling variables like backfill surface settlement, lateral deformation of facing, and permanent relocation of the wall. A parametric study was performed based on a non-linear elastoplastic constitutive model known as the hardening soil model with small-strain stiffness, HSsmall. The analyses were conducted using PLAXIS 2D, a Finite Element Method (FEM) program, under plane-strain conditions to study the effect of the number of geogrid layers and the axial stiffness of geogrids on the performance of SMSE walls. In this study, three areas of damage (minor, moderate, and severe) were observed and, in all cases, the wall has not completely entered the stage of destruction. For the base model (Model A), at the highest ground acceleration coefficient (1 g), in the moderate damage state, the fragility probability was 76%. These values were 62%, and 54%, respectively, by increasing the number of geogrids (Model B) and increasing the geogrid stiffness (Model C). Meanwhile, the fragility values were 99%, 98%, and 97%, respectively in the case of minor damage. Notably, the probability of complete destruction was zero percent in all models.

• Journal of the Korean Geosynthetics Society
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• v.12 no.4
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• pp.133-141
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• 2013

This paper describes the earthquake risk evaluation of 15 sites of architectural heritages, which are considered ground conditions of sites in Seoul. In order to acquire the input data of earthquake response analysis, surface wave exploration was performed at the site. Earthquake response analysis and 3D earthquake safety evaluation were carried out under the base of scenario earthquakes. Ground displacements of areas, which are located on architectural heritages, are showed about 0.5 mm ~ 9.7 mm, and it was analyzed to small affected by earthquakes. In case of Naksungdae three-story stone pagoda, ground displacement is similar to the others. However, displacement of three-story stone pagoda with granite is 30 mm on the top, because the greatest occurrence of that is caused by stress release at seismic wave effect.

• Journal of Sensor Science and Technology
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• v.32 no.3
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• pp.131-139
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• 2023

Ascorbic acid plays a crucial role in the regulation of neurotransmitters and enzymes in the central nervous system. Maintaining an optimal level of ascorbic acid, which is between 0.6-2 mg/dL, is vital for preventing oxidative stress and associated health conditions, such as cancer, diabetes, and liver disease. Therefore, the detection of ascorbic acid is of the utmost importance. Electrochemical sensing has gained significant attention among the various detection methods, owing to its simplicity, speed, affordability, high selectivity, and real-time analysis capabilities. However, conventional electrodes have poor signal response, which has led to the development of modified electrodes with better signal response and selectivity. Carbon nanotubes (CNTs) and their composites have emerged as promising materials for the electrochemical detection of ascorbic acid. CNTs possess unique mechanical, electrical, and chemical properties that depend on their structure, and their large surface area and excellent electron transport properties make them ideal candidates for electrochemical sensing. Recently, various CNT composites with different materials and nanoparticles have been studied to enhance the electrochemical detection of ascorbic acid. Therefore, this review aims to highlight the significance of CNTs and their composites for improving the sensitivity and selectivity of ascorbic acid detection. Specifically, it focuses on the use of CNTs and their composites in electrochemical sensing to revolutionize the detection of ascorbic acid and contribute to the prevention of oxidative stress-related health conditions. The potential benefits of this technology make it a promising area for future research and development.