• The Journal of Sustainable Design and Educational Environment Research
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• v.11 no.1
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• pp.23-31
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• 2012

The number of school crime has grown continuously for last ten years and its intensity also has reached to serious condition. The concept of CPTED(Crime Prevention through Environmental Design) needs to be focused for improving school environment regarding this context. The exterior space of school environment is variously exposed to school crimes committed by colleague students and also intruders. From the perspective of school CPTED, Natural surveillance as one of the practical strategies requires the micro-scale analysis which clarifies local visibility at each different school exterior space. Thus, the purpose of this research is to develop the analysis method clarifying visibility condition at exterior space of school environment, which supports finding the condition of natural surveillance. The programmed analysis algorithm generated quantitative results clarifying Degree for static visibility and Clustering Coefficient for user tracking visibility. The result of this study produced the analysis method feasible to clarify weak natural surveillance conditions at school exterior spaces. Also, it is expected that the developed analysis method will be used to improve the layout of school exterior space from the perspective of CPTED.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.22 no.3
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• pp.31-36
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• 2022

Recently, drones are being used in various fields, and drone technology is also developing. The risks of drones are increasing, then technology to detect drones is important. However, it is extremely difficult to detect and recognize drones due to the low level radar cross section of the commercial drones. In this paper, a signal processor structure that was mounted the miniaturized and light-weighted was designed. in order to process large amounts of data in real time, parallel processing was performed for each channel and an algorithm was applied to shorten the operation time in each step. As a test of verifing the detection performance through test, it was confirmed that the structure design works in real time.

• Korean Journal of Artificial Intelligence
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• v.12 no.3
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• pp.17-24
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• 2024

This study aims to derive a technology development roadmap in related fields by utilizing patent documents of financial technology. To this end, patent documents are extracted by dragging technical keywords from prior research and related reports on financial technology. By applying the TF-IDF (Term Frequency-Inverse Document Frequency) technique in the extracted patent document, which is a text mining technique, to the extracted patent documents, the Latent Dirichlet Allocation (LDA) algorithm was applied to identify the keywords and identify the topics of the core technologies of financial technology. Based on the proportion of topics by year, which is the result of LDA, promising technology fields and convergence fields were identified through trend analysis and similarity analysis between topics. A first-stage technology development roadmap for technology field development and a second-stage technology development roadmap for convergence were derived through network analysis about the technology data-based integrated management system of the high-dimensional payment system using RF and intelligent cards, as well as the security processing methodology for data information and network payment, which are identified financial technology fields. The proposed method can serve as a sufficient reason basis for developing financial technology R&D strategies and technology roadmaps.

• Journal of Life Science
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• v.20 no.7
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• pp.1054-1065
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• 2010

SH21B is a natural composition composed of seven herbs: Scutellaria baicalensis Georgi, Prunus armeniaca Maxim, Ephedra sinica Stapf, Acorus gramineus Soland, Typha orientalis Presl, Polygala tenuifolia Willd and Nelumbo nucifera Gaertner (Ratio 3:3:3:3:3:2:2). In our previous study, we reported that SH21B inhibited adipogenesis and fat accumulation in 3T3-L1 cells through modulation of various regulators in the adipogenesis pathway. The aim of this study was to analyze the transcriptome profiles for the anti-adipogenic effects of SH21B in 3T3-L1 cells. Total RNAs from SH21B-treated 3T3-L1 cells were reverse-transcribed into cDNAs and hybridized to Affymetrix Mouse Gene 1.0 ST array. From microarray analyses, we identified 2,568 genes of which expressions were changed more than two-fold by SH21B, and the clustering analyses of these genes resulted in 9 clusters. Three clusters among the 9 showed down-regulation by SH21B (cluster 4, cluster 6 and cluster 9), and two clusters showed up-regulation by SH21B (cluster 7 and cluster 8) during the adipogenesis of 3T3-L1 cells. It was found that many genes related to cell proliferation and adipogenesis were included in these clusters. Clusters 4, 6 and 9 included genes which were related with adipogenesis induction and cell cycle arrest. Clusters 7 and 8 included genes related to cell proliferation as well as adipogenesis inhibition. These results suggest that the mechanisms of the anti-adipogenic effects of SH21B may be the modulation of genes involved in cell proliferation and adipogenesis.

• Spatial Information Research
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• v.23 no.4
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• pp.13-22
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• 2015

There has been much interest in the VWorld open platform with the addition of a variety of contents or services such as 2D map, 3D terrain, 3D buildings, and thematic map since 2012. However, the VWorld system architecture was not stable for the system overload. For example, the system was stopped due to the rapidly increasing user accesses when the 3D terrain service of the North Korea and the Baekdu mountain was launched at September 2012 and September 2013, respectively. It was because the system architect has just extended the server system and the network bandwidth whenever the rapid increase of user accesses occurs or new service starts. Therefore, this study proposes a new VWorld system architecture that can reliably serve the huge volume of National Spatial Data by applying the new technologies such as CDN, visualization and clustering. Finally, it is expected that the results of this study can be used as a basis for the next VWorld system architecture being capable of a huge volume of spatial data and users.

• Monthly Notices of the Royal Astronomical Society
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• v.496 no.4
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• pp.4787-4821
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• 2020

The merging rate of cosmic structures is computed, relying on the ansatz that they can be predicted in the initial linear density field from the coalescence of critical points with increasing smoothing scale, used here as a proxy for cosmic time. Beyond the mergers of peaks with saddle points (a proxy for halo mergers), we consider the coalescence and nucleation of all sets of critical points, including wall-saddle to filament-saddle and wall-saddle to minima (a proxy for filament and void mergers, respectively), as they impact the geometry of galactic infall, and in particular filament disconnection. Analytical predictions of the one-point statistics are validated against multiscale measurements in 2D and 3D realizations of Gaussian random fields (the corresponding code being available upon request) and compared qualitatively to cosmological N-body simulations at early times (z ≥ 10) and large scales (≥5 Mpc h^-1). The rate of filament coalescence is compared to the merger rate of haloes and the two-point clustering of these events is computed, along with their cross-correlations with critical points. These correlations are qualitatively consistent with the preservation of the connectivity of dark matter haloes, and the impact of the large-scale structures on assembly bias. The destruction rate of haloes and voids as a function of mass and redshift is quantified down to z = 0 for a Lambda cold dark matter cosmology. The one-point statistics in higher dimensions are also presented, together with consistency relations between critical point and critical event counts.

• Journal of IKEEE
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• v.23 no.1
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• pp.280-288
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• 2019

In the CR-enabled MANET, routing paths can be easily destroyed due to node mobility and channel unavailability (due to the emergence of the PU of a channel), resulting in significant overhead to maintain/recover the routing path. In this paper, network caching is actively used for route maintenance, taking into account the properties of the CR. In the proposed scheme, even if a node detects that a path becomes unavailable, it does not generate control messages to establish an alternative path. Instead, the node stores the packets in its local cache and 1) waits for a certain amount of time for the PU to disappear; 2) waits for a little longer while overhearing messages from other flow; 3) after that, the node applies local route recovery process or delay tolerant forwarding strategy. According to the simulation study using the OPNET simulator, it is shown that the proposed scheme successfully reduces the amount of control messages for path recovery and the service latency for the time-sensitive traffic by 13.8% and 45.4%, respectively, compared to the existing scheme. Nevertheless, the delivery ratio of the time-insensitive traffic is improved 14.5% in the proposed scheme.

• Bulletin of the Korean Chemical Society
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• v.34 no.7
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• pp.1972-1984
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• 2013

Microtubules play an important role in intracellular transport, mobility, and particularly mitosis. Paclitaxel (Taxol$^{TM}$) and paclitaxel-like compounds have been shown to be anti-tumor agents useful for various human tumors. Paclitaxel-like compounds operate by stabilizing microtubules through interface binding at the interface between two ${\beta}$-tubulin monomers in adjacent protofilaments. In this paper we present the elucidation of the structural features of paclitaxel and paclitaxel-like compounds (e.g., epothilones) with microtubule stabilizing activities, and relate their activities to spatial and chemical features of the molecules. CATALYST program was used to generate three-dimensional quantitative structure activity relationships (3D-QSARs) resulting in 3D pharmacophore models of epothilone- and paclitaxel-derivatives. Pharmacophore models were generated from diverse conformers of these compounds resulting in a high correlation between experimental and predicted biological activities (r = 0.83 and 0.91 for epothilone and paclitaxel derivatives, respectively). On the basis of biological activities of the training sets, five- and four-feature pharmacophore hypotheses were generated in the epothilone and paclitaxel series. The validation of generated hypotheses was achieved by using twelve epothilones and ten paclitaxels, respectively, which are not in the training sets. The clustering (grouping) and merging techniques were used in order to supplement spatial restrictions of each of hypothesis and to develop more comprehensive models. This approach may be of use in developing novel inhibitor candidates as well as contributing a better understanding of structural characters of many compounds useful as anticancer agents targeting microtubules.

• Journal of Gastric Cancer
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• v.4 no.3
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• pp.180-185
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• 2004

Recently, we experienced two advanced gastric cancer (AGC) patients younger than 17 years of age. The first case was a 15-year, 2-month-old male who had suffered from epigastric soreness for 5 weeks. His grandfather died of gastric cancer at 39 years of age. Under the diagnosis of AGC, he underwent a total gastrectomy with D2 lymph node dissection. There was no evidence of distant metastasis. Pathologic examination revealed a 4.5$\times$4 cm, signet ring cell adenocarcinoma with subserosal invasion and with metastasis in 9 of 42 regional lymph nodes (T2bN2M0). The second case was a 17-year, 11-month-old male who had suffered from epigastric pain for 2 years without familial clustering. Under the diagnosis of AGC, he underwent a distal subtotal gastrectomy with D2 lymph node dissection. There was no evidence of distant metastasis. Pathologic examination revealed a 3$\times$2 cm, signet ring cell adenocarcinoma with subserosal invasion and with metastasis in 9 of 45 regional lymph nodes (T2bN2M0). The two patients have been alive without recurrence for 27 months and 4 months, respectively. Even among teenagers, patients with abdominal complaints should be subjected to a thorough examination of the gastrointestinal tract.

• The KIPS Transactions:PartB
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• v.15B no.3
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• pp.205-210
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• 2008

A new approach is proposed for restoration of corrupted regions and segmentation in natural text images. The challenge is to fill in the corrupted regions on the basis of color feature analysis by second order symmetric stick tensor. It is show how feature analysis can benefit from analyzing features using tensor voting with chromatic and achromatic components. The proposed method is applied to text images corrupted by manifold types of various noises. Firstly, we decompose an image into chromatic and achromatic components to analyze images. Secondly, selected feature vectors are analyzed by second-order symmetric stick tensor. And tensors are redefined by voting information with neighbor voters, while restore the corrupted regions. Lastly, mode estimation and segmentation are performed by adaptive mean shift and separated clustering method respectively. This approach is automatically done, thereby allowing to easily fill-in corrupted regions containing completely different structures and surrounding backgrounds. Applications of proposed method include the restoration of damaged text images; removal of superimposed noises or streaks. We so can see that proposed approach is efficient and robust in terms of restoring and segmenting text images corrupted.