• Journal of the Korean Chemical Society
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• v.55 no.4
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• pp.638-643
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• 2011

The synthesis of biologically active 1H-1,4-diazepines 4a-d and 3H-1,5-benzodiazepines 5a-d in good yields, from the heterocyclization reaction of 2-(4-methylthio benzenesulfonyl)-1,3-dimethyl/1-methyl-3-phenyl/1,3-diphenyl/1-methyl-3-ethoxy propane-1,3-dione 3a-d with ethylenediamine (EDA) and o-phenylenediamine (o-PDA), respectively, in the presence of silica sulfuric acid (SSA) is described. The novel ${\beta}$-diketones/${\beta}$-ketoesters 3a-d were synthesized by the condensation reaction of 4-methylthiobenzenesulfonyl chloride 1 with various ${\beta}$-diketones/${\beta}$-ketoesters 2a-d. All structures of the newly synthesized compounds were elucidated by elemental analysis and spectral studies. The compounds 4a-d and 5a-d have been screened for antimicrobial, antifungal and anthelmintic activity.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.33 no.6
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• pp.244-249
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• 2023

In this study, various experimental parameters were investigated for high-purity C₃A synthesis. As a results of experiment, it was verified that the calcined temperature was the most important parameter for the synthesis of high-purity C₃A. In addition, more synthesis time was needed when large amount of C₃A synthesis to achieve high-purity. Meanwhile, the C₃A blended with CaCO₃ showed different reaction products compared to normal cement because C15 and C30 had monocarbocaluminate as a reaction product at early stage of hydration. Furthermore, the production amount and formation rate of monocarboaluminate formation was different varying with the CaCO₃ a mounts.

• Journal of the Korean Society of Radiology
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• v.10 no.8
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• pp.571-576
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• 2016

3D printing has recently been used in various fields. Among various applications, 3D face data must be generated for 3D face printing. A laser scanner is used to acquire 3D face data, but there is a restriction that a person should not move during scanning. In this paper, we propose a 3D face modeling method based on a single image and a face transformation system to use the generated 3D face for virtual cosmetic surgery. We have defined facial feature points from the 3D face database for 3D face data generation. After extracting feature points from a single face image, 3D face of the input face image is generated corresponding to the 3D face feature points defined from the 3D face database. After 3D face modeling, 3D face modification part is applied for use such as virtual cosmetic surgery.

• Journal of Microbiology and Biotechnology
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• v.25 no.11
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• pp.1842-1848
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• 2015

Cyanidin-3-glucoside (C3G) has been known to be more bioavailable than cyanidin-3-rutinoside (C3R), the most abundant anthocyanin in black raspberry (Rubus occidentalis). The aim of this study was to enhance the bioavailability of anthocyanins in black raspberry by cleaving ʟ-rhamnose in C3R using crude enzyme extracts (CEEs) from Aspergillus usamii KCTC 6956, A. awamori KCTC 60380, A. niger KCCM 11724, A. oryzae KCCM 12698, and A. kawachii KCCM 32819. The enzyme activities of the CEEs were determined by a spectrophotometric method using ρ-nitrophenyl-rhamnopyranoside and ρ-nitrophenyl-glucopyranoside. The CEE from A. usamii had the highest α-ʟ-rhamnosidase activity with 2.73 U/ml at 60℃, followed by those from A. awamori and A. niger. When bioconversion of C3R to C3G in black raspberry was analyzed by HPLC-DAD, the CEEs from A. usamii and A. awamori hydrolyzed 95.7% and 95.6% of C3R to C3G, respectively, after 2 h incubation. The CEEs from A. kawachii and A. oryzae did not convert C3R to C3G in black raspberry.

• Journal of Dental Rehabilitation and Applied Science
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• v.31 no.4
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• pp.294-300
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• 2015

Purpose: The purpose of this study was to measure the color of low viscosity bulk-fill resin with a capping layer and to compare it with the color of microhybrid composite resin. Materials and Methods: A low viscosity bulk-fill resin (SDR) and microhybrid composite resin of shade A2 (A2) or A3 (A3) were fabricated to 4 mm thickness and light cured for 20 seconds. CIE $L^*a^*b^*$ values of the resin specimens were measured with a colorimeter. Then shade A2 and A3 microhybrid composite resin was capped over low viscosity bulk-fill resins in 2 mm thickness (SA2, SA3). The resin specimens were light cured for 20 seconds and the color was measured and analyzed (n = 10). Color differences (${\Delta}E$) between SA2 and A2, SA3 and A3 were also calculated. Results: $L^*$ value was highest in SDR followed by SA2 and SA3. $L^*$ value of A2 and A3 was the lowest. $a^*$ value was lowest in SDR followed by SA2 and SA3, and A2 and A3 was the highest. $b^*$ value was lowest in SDR followed by A2 and SA2, and A3 and SA3 was the highest. ${\Delta}E$ between A2 and SA2 (${\Delta}E=3.4$), and that between A3 and SA3 (${\Delta}E=3.1$) was lower than the perceptible color difference threshold of ${\Delta}E=3.7$. Conclusion: ${\Delta}E$ between low viscosity bulk-fill resin with a capping layer and microhybrid resin was lower than the perceptible color difference threshold.

• Bulletin of the Korean Chemical Society
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• v.35 no.10
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• pp.2990-2994
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• 2014

The studies on design and synthesis of new monocyclic ${\beta}$-lactam esters 4(R/S)-(1'-methoxycarbonylpropyl- 2'(R/S)-thio)-3(R)-phenylacetamidoazetidin-2-one (3a) and 4(R/S)-(1'-methoxycarbonyl-2'-methylpropyl-2'- thio)-3(R)-phenylacetamidoazetidin-2-one (3b) were described. Compounds 3a and 3b were specifically designed to retain all penicillin substructures except the bicyclic system, which would be conceived by cleaving the C(3)-N(4) bond of penicillin G. Compounds 3a and 3b are of particular interest in the context of the structural elucidation of monocyclic ${\beta}$-lactams originated from penicillin. Key intermediates, ${\beta}$-mercapto esters 6a and 6b, were synthesized from conjugate acids 4a and 4b using three-step synthetic sequences, respectively, and 4(S)-acetoxy-3(S)-phenylacetamidoazetidin-2-one (7) was obtained from the degradation of penicillin G. Reactions of 6a and 6b with 7, thus obtained, provided the target compounds 3a and 3b, respectively.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1247-1253
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• 2014

Mutations in the DNMT3A and IDH genes represent the most common genetic alteration after FLT3/NPM1 in acute myeloid leukemia (AML). We here analyzed the frequency and distribution pattern of DNMT3A and IDH mutations and their associations with other molecular markers in normal karyotype AML patients. Fortyfive patients were screened for mutations in DNMT3A (R882), IDH1 (R132) and IDH2 (R140 and R172) genes by direct sequencing. Of the 45 patients screened, DNMT3A and IDH mutations were observed in 6 (13.3%) and 7 (15.4%), respectively. Patients with isolated DNMT3A mutations were seen in 4 cases (9%), isolated IDH mutations in 5 (11.1%), while interestingly, two cases showed both DNMT3A and IDH mutations (4.3%). Nucleotide sequencing of DNMT3A revealed missense mutations (R882H and R882C), while that of IDH revealed R172K, R140Q, R132H and R132S. Both DNMT3A and IDH mutations were observed only in adults, with a higher frequency in males. DNMT3A and IDH mutations were significantly associated with NPM1, while trends towards higher coexistence with FLT3 mutations were observed. This is the first study to evaluate DNMT3A/IDH mutations in Indian patients. Significant associations among the various molecular markers was observed, that highlights cooperation between them and possible roles in improved risk stratification.

• Cartoon and Animation Studies
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• s.48
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• pp.199-215
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• 2017

Recently, a drone is used for the general purpose application although the drone was builtfor the military purpose. A drone is actively used for the creation of contents, and an image acquisition. In this paper, we develop a 3D library module platform using 3D mesh model data, which is generated by a drone image and its point cloud. First, a lot of 2D image data are taken by a drone, and a point cloud data is generated from 2D drone images. A 3D mesh data is acquired from point cloud data. Then, we develop a service library platform using a transformed 3D data for multi-purpose uses. Our platform with 3D data can minimize the cost and time of contents creation for special effects during the production of a movie, drama, or documentary. Our platform can contribute the creation of experts for the digital contents production in the field of a realistic media, a special image, and exhibitions.

• Korean Journal of Plant Resources
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• v.12 no.2
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• pp.161-165
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• 1999

The objective of this research was to find a useful genetic information for yield characteristics of tillering maize hybrids. Fls were planted under three plant densities at the experimental field of Agricultural College of Chungnam National University. The fresh yield of P1213749//FR805/IK3, FR805/IK3//Waesungri and IK/LE/FR805/IK3 was 7,862kg/10a, 8,290kg/10a and 7,746kg/10a, respectively. The fresh yield of tillering maize hybrids was higher than that of P3394 hybrids. The dry matter yield of P3394 hybrid was 1,430kg/10a with low plant density(4,800p1an1s) and that of PI213749//FR805/IK3 was 1,834kg/10a, the dry weight of FR805/IK3//Waesungri was 1,836kg/10a and that of IK/LE/FR805/IK3 was 1,810kg/10a. Grain yields per 10a of IK/LE//FR805/IK3(783kg) was the highest in 4,800plants/10a, and that of check hybrid was higher than the tillering maize hybrids in 3,600plants/10a, but grain yield per 10a of IK/LE/FR805/IK3 was 752kg, and that of P1213749/Dangjin//IK/LE(699kg) was higher than P3394 hybrid(680kg) with 2,400plants/10a.

• Journal of Digital Convergence
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• v.12 no.3
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• pp.263-268
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• 2014

The purpose of this study is to provide a quantitative evaluation index of object-oriented software development productivity for EJB 3.0 and EJB 3.1. A lightweight container architecture is a newly-developed architecture in order to solve demerits that N-Tiers enterprise architecture has and to support merits therein. A lightweight container architecture is not as heavy as EJB(Enterprise JavaBeans) architecture is, whereas it provides all the functionality of the EJB container. However, there have been insufficient studies on a performance evaluation of EJB 3.0 and EJB 3.1 on an identical platform. Since a quantitative analysis has been performed only with respect to a partial LoC(Line of Code) analysis, there have been insufficient objective evaluation indeces and guidelines for a new specification released. Accordingly, there has been limited evaluation of software development productivity and on new innovations in a project. Therefore, this study designed and implemented a movie reservation system in EJB 3.0 and EJB 3.1, which was based on the same development platform environment. This study then intends to provide evaluation guidelines for an objective software development productivity cl LoC(Lineand standardization thereof by development platform environment.