• The Journal of the Korea Contents Association
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• v.9 no.4
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• pp.355-363
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• 2009

Increased oxidative stress by abnormal mitochondrial function can damage cell signal transduction and gene expression, and induce insulin resistance or diabetes. Autophagy, however, improve insulin resistance by clearance of malfunctioning mitochondria. Exercise also recovers the muscle dysfunction and degeneration by activating mitochondrial biogenesis. As it seems that exercise and autophagy might act as an orchestrated network to induce mitochondrial biogenesis, we investigated whether autophagy is involved in AMPK signal pathway stimulated by exercise or AICAR to increase mitochondrial biogenesis. And it showed that PGC-1 and mtTFA, but not autophagy marker LC3 mRNA expression were significantly increased by 6 hr of acute exercise. On the other hand, PGC-1 and mtTFA mRNA expression were upregulated by AICAR treatment to C2C12 myotube. However these genes were not inhibited by LC3 siRNA transfection. These results provide the evidence that autopahgy affects on mitochondrial biogenesis through different signal pathway from AMPK signal transduction.

• Journal of the Korean Applied Science and Technology
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• v.38 no.3
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• pp.762-770
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• 2021

The purpose of this study was to analyze the effect on the vertical ground reaction force, the elapsed time, and the center of pressure factors during gait by maepsi exercise program, which is a whole body exercise, to middle-aged women for 8 weeks. A total of 25 subjects participated in this study, 13 in the exercise group(age, 41±4.4 years; heigh, 162.5±5.8cm; weight, 57.8±6.7kg; body mass, 21.9±2.4kg/m2) and 12 in the control group(age, 41.1±5.6 years; height, 160.9±5.5 cm; weight, 576.2±8.1 kg; body mass, 21.7±2.9 kg/m2). In the exercise group, the maepsi exercise program consisting of 7 areas, 23 types and 77 movements, was conducted 3 times a week for 8 weeks. Two-way repeated measures ANOVA was performed to verify the ground reaction force factors during gait, and the post-test was analyzed with bonferroni adjustment(a=.05). In the exercise group, compared to the control group, the exercise group showed higher values than the control group in the elapsed time to FMWA and FPO, vertical ground reaction force at FMWA and FPO, and RMS factors of COP in the AP direction. Therefore, it was found that the 8-week maepsi exercise program improved the acceleration and deceleration exercise functions of middle-aged women who performed gait.

• Journal of Industrial Convergence
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• v.22 no.3
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• pp.91-100
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• 2024

Coronary artery disease(CAD) is associated with a high risk of recurrence and an increased mortality rate upon recurrence. Consequently, there is a need for continuous health behavior recommendations from medical staff. Therefore, a study was conducted on 219 patients hospitalized for coronary angiography. The study aimed to investigate the influence of medical staff recommendations on exercise adherence among CAD patients. In conclusion, regular exercise(RE) recommendation(OR 3.52, p=.036) and dietary advice from medical staff(OR 6.48, p=.022), having high exercise self-efficacy(OR 1.36, p=.001) positively affected RE adherence. Therefore, medical staff should strengthen personalized recommendations for RE and healthy diets, as well as develop exercise self-efficacy enhancement programs to encourage patient participation. Future research is recommended to explore the impact of the degree and method of medical staff recommendations on self-management practices among CAD patients.

• Journal of the korean academy of Pediatric Dentistry
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• v.30 no.4
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• pp.563-575
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• 2003

The purpose of this study was to investigate differences in craniofacial characteristics of professional sportsmen who have practiced since their prepubertal periods. From the standardized lateral and P-A cephalograms of 137 sportsmen, 7 angular, 19 linear, 4 ratio, and 2 index measurements were measured and evaluated by means of statistical methods. The samples were divided into three groups: Group 1; ice hockey(n=17), foot-ball(n=27), basketball(n=16) Group 2; baseball(n=16), gymnastics(n=13), and Group 3; judo(n=18), ssireum(n=10), weight lift(n=20). The results were as follows: It seemed obvious that the cephalic indices of the 3 groups exhibited brachycephalic headform (Group 1; $0.85{\pm}0.04$, Group 2; $0.84{\pm}0.04$, Group 3; $0.83{\pm}0.06$) and there was no statistical difference among the groups (p>0.05). The facial indices of the Group 1 ($0.93{\pm}0.05$) and Group 2 ($0.93{\pm}0.04$) exhibited definite leptoprosopic facial forms while the Group 3 ($0.90{\pm}0.04$) showed more or less euryprosopic facial form, and there appeared significant difference between the Group 1 and 3 (p<0.05), and also between the Group 2 and 3 (p<0.05). There appeared strong relationships between the facial indices and the facial axis angle, mandibular plane angle, total craniofacial height, total facial height, upper anterior dental height, lower anterior dental height, mandibular length, lower anterior facial height ratio, and especially with lower anterior facial height (p<0.001). It seemed that most of the vertical facial measurements of the Group 1 and 2 appeared to be larger than those of the Group 3.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.12 no.1
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• pp.53-62
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• 2018

In this study, we developed a smart 1RM system for national health management and physical fitness, which enables quantitative 1RM measurement in various types of exercise using digital pulley technology, and to test the effect on training by using it. We developed the smart 1RM system, which is composed of portable muscle strength measuring device, Bluetooth communication based mobile phone data transmission and circuit diagram, and height adjustable system body. We recruited the 30 participants with 20th aged and divided into training and non-performing groups with 15 participants randomly. The participants performed 5 sets of elbow, lumbar, knee extension / flexion 10 times using smart 1RM system and the experimental period was 3 days a week for a total of 8 weeks. The experimental results showed that the maximum strength of the elbow, lumbar, and knee joints was significantly improved before and after maximal muscle strength training in the training group. Oxygen intakes during 1RM exercise mode showed 10.91% than endurance. To verify the validity of the smart 1RM maximal strength data, the reliability was 0.895 (* p <0.00). This study can be applied to the early rehabilitation treatment of the elderly and rehabilitation patients more quantitatively using the national health care.

• Investigative Magnetic Resonance Imaging
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• v.12 no.1
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• pp.33-39
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• 2008

Purpose : There is debate concerning the observation of metabolite changes on MRS at the designated cortex during some tasks. The purpose of this study is to assess the change of the lactate content at the motor cortex during hand-grasping tasks with performing real-time fMRI-guided fMRS. Materials and Methods : Seven healthy volunteers (23-28 years old) underwent realtime fMRI during right hand grasping tasks with using a 1.5 T system. After confirming the activating area, single voxel MRS was preformed at 1) the baseline, 2) during the task and 3) after the task on the activating cortex. The three consecutive spectra were compared for observing the changes of the lactate content by the tasks. The Cho/Cr, NAA/Cr and Lac/Cr ratios were calculated manually from those spectra. Results : MRS during the tasks revealed the lactate peaks at the 1.33 ppm resonance frequency with great conspicuity at the activated area, which was identified on the real-time fMRI. After the task scan, the lactate peaks completely disappeared and the spectra recovered to the values of the baseline scan in all volunteers. At baseline, during the task and after the task, the Cho/Cr ratios were 0.81, 0.76 and 0.77, respectively, and the NAA/Cr ratios were 1.68, 1.65 and 1.72, respectively, and the Lac/Cr ratios were 0.28, 0.41 and 0.30, respectively. During the task, Lac was significantly increased by 46%. Conclusion : We observed prominent lactate peaks on MRS during hand-grasping tasks at the activated area, as was shown on the real-time fMRI. We suggest that fMRS can be used as a sensitive tool for observing the metabolite changes of the functioning brain.

• Journal of Convergence for Information Technology
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• v.7 no.6
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• pp.35-43
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• 2017

The purpose of this study was to analyze the converged influencing factors on the stages of exercise behavior changes in shift work nurses. The subjects were 120 shift work nurses working in hospitals who understood the purpose of the study and agreed to participate in the study. Data were analyzed using frequency, percentage, mean, standard deviation, t-test, $X^2$ test, and multiple logistic regression analysis. The exercise motivation factors of shift work nurses had a significant effect on stages of exercise behavior change (${\beta}=2.480$, p=.022), health status perceptions(${\beta}=1.151$, p=.013). Social support factors (${\beta}=1.819$, p=.002) and marital status (${\beta}=-1.820$, p=.004) also had significant effects on the stages of exercise behavior change of shift work nurses. In other words, subjects with change in exercise behavior had 11.9 times higher motivation and 3.1 times higher health status perception than those without change in exercise behavior, social support was 6.1 times higher, and unmarried subjects showed 16 times showed higher than that of married subjects. Therefore, it is important to develop a strategy to practice continuous and regular exercise in consideration of the exercise motivation, social support, and health status perception of the nurses in shift work.

• Journal of Life Science
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• v.15 no.1 s.68
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• pp.80-86
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• 2005

To achieve the purpose of this study, forty-eight male Sprague-Dawley rats were assigned to control and three endurance exercise group. 36 rats were forced to exercise according to exercise intensity for 8 weeks and 12 rats were untrained for control group. Cardiac cytosol was extracted from cardiac tissue and cardiac mitochondria was purified from the cytosol. Purified mitochondria were separated into four fraction: inner membrane, outer membrane inter membrane space and matrix. The changes of cytosolic and mitochondrial LDH isozymes activity were measure. Relative activity $(\%)$ of cytosol for low and control group showed the following order of prevalence $AB_3>A_2B_2>B_4>A_3B>A_4$ for moderate and high group : $AB_3>B_4>A_2B_2>A_3B>A_4$. Outer membrane for low group showed $AB_3>B_4>A_2B_2$, for moderate group:$ B_4>AB_3>A_2B_2$, for high and control group: $B_4>A_3B$. Inter membrane space for low, moderate and high group showed $B_4>AB_3>A_2B_2>A_3B>A_4$, for control group: $B_4>A_3B>AB_3>A_2B_2>A_4$. Inner membrane for all group showed $B_4>AB_3>A_2B_2>A_3B>A_4$. Matrix for control, low, moderate and high group showed $B_4>AB_3>A_2B_2>A_3B>A_4$. These results suggest that long term exercise intensity effect on cardiac tissue cytosolic and mitochondrial activity and $A_4,\;A_3B,\;A_2B_2,\;AB_3\;and\;B_4$ isozymes were found entirely in mitochondrial fraction.

• 대한관절경학회:학술대회논문집
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• 2008.04a
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• pp.23-28
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• 2008

1. 손상받은 조직을 보호하면서 동시에 주위 조직과의 유착을 방지하고 soft tissue의 pliability를 유지시켜 관절 운동 범위를 향상하기 위해 통증을 유발하지 않는 범위 내에서 부드러운 수동 관절 운동을 먼저 실시한다. 2. 모든 재활 프로그램은 환자의 개개인의 특성에 맞춰 운동 내용과 시기를 조정해야 한다. : Important to individualize rehab. program. 3. 능동적 관절운동 (active ROM)은 수술한 조직이 치유될 충분한 시간이 경과되었거나 환자가 통증없이 독립적인 견관절 운동이 가능할 때 실시한다. 4. Strengthening of the dynamic stabilizer(muscles around shoulder joint) 가 모든 shoulder instability 재활에 가장 기본적인 요소이다.

• Journal of Korea Entertainment Industry Association
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• v.13 no.7
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• pp.461-468
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• 2019

The purpose of this study was to investigate effect of upper cervical stabilization exercise on Temporomandibular Disorder(TMD) and pressure pain threshold. 36 subjects were divided into two groups: upper cervical stabilization exercise group(UCSEG) and control on three times a week for a total of four weeks. The upper cervical stabilization group showed more significant effect than the control group (p <.01, 95% CI: 8.074, 16.899). (p <.01, 95% CI: .826, 3.243). In the change of pressure pain threshold, the upper cervical stabilization group showed significant improvement in both the masticatory muscle(p <.01, 95% CI: .251, 1.382) and masticatory muscle(p <.01, 95% CI: .462, 1.826).The results of this study showed that the upper cervical stabilization exercise was effective that TMD. It will be able to provide more effective interventions for patients suffering from TMD, and to suggest new approaches for TMD patients.