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Effect of Citric Acid and Tetracycline HCl Root Conditioning on rhBMP-2 on Human Periodontal Ligament Fibroblast and Osteoblast cell (구연산과 테트라싸이클린으로 처리한 치근면에서 rhBMP-2가 치주인대섬유아세포와 골아세포의 활성에 미치는 영향)

  • Shim, Jung-Min;Han, Soo-Boo;Seol, Yang-Jo;Lee, Yong-Moo;Kim, Kyeong-Hwa;Kye, Seung-Beom;Choi, Sang-Mook;Chung, Chong-Pyoung
    • Journal of Periodontal and Implant Science
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    • v.31 no.1
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    • pp.21-41
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    • 2001
  • The goal of Periodontal treatment is predictable periodontal regeneration. But until now, many products including GTR materials and growth factors are beyond of complete regeneration. BMP can induce ectopic bone formation when implanted into sites such as rat muscle and can greatly enhance healing of bony defects when applied exogenously. BMP can promote periodontal regeneration by their ability to stimulate new bone and new cementum formation. But little is known about optimal conditions required for the application. Root conditioning is used for bioacive root change so altered root surface provides a substrate that promotes chemotaxis, migration and attachment of peridontal cells encouraging connective attachment to the denuded root surface. The aim of this study is to investigate whether the acid conditioning change effect of rhBMP-2 on human periodontal ligament cell and osteoblast cell line. 288 periodontally involved root dentin slices are divided into 6 groups, each 48, 1)control, 2)treated with BMP, 3)treated with citric acid 4)treated with citric acid+BMP 5)treated with tetracycline 6)treated with TC+BMP. Each group was devided half, so 12 root dentin slices were seeded with periodontal ligament cells and 12 were seeded with osteoblasts. At day 2 and 7, cell number, protein assay, ALP activitiy was measured. To investigate morphology of cultured cells, SEM was employed. Statistical analysis was performed with SPSS 8.0 either t-test or ANOVA test. The results are ; Protein assay and cell number was slightly decreased in CA+BMP group compared to Ca group but it was not statistically significant and ALP activity was much more increased in CA+BMP group compared to CA group so there was no statistically significance between BMP and CA+BMP group and statistically significant compared to control group. Cell number and protein assay was slightly increased in TC group and ALP activity was much less the BMP group and CA group. Cell number and protein and ALP activity was not much increased in TC+BMP group. TC group and TC+BMP group showed cell morphology change in SEM. This results suggested that application of root surface with citric acid before BMP treatment might give better result in periodontal regeneration.

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The Influences of a Team System's Introduction to Hospital Organization, Regarding Job Satisfaction and Organization Commitment (병원조직에 팀제 도입이 팀직무만족과 팀조직 몰입에 미치는 영향)

  • Choi, Soon-Yeon;Nam, Eun-Woo
    • Korea Journal of Hospital Management
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    • v.5 no.1
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    • pp.232-271
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    • 2000
  • The introduction of a team system to any organization is usually to improve that organizations dynamics, by increasing the proper adaptation to rapidly changing environments, by reducing approval procedures, and by promoting power authorization. In this regard, this study was carried out in an attempt to determine (1) whether or not the introduction of a team system can be as effective in hospital organizations as it has been in business organizations, and (2) what behavior factors influence such effectiveness. For the current study, questionnaires were distributed to the employees of a university hospital in Pusan. Four hundred eighty three of them(94.7%) were retrieved and analyzed through statistical processes. The three types of variables that were found to influence team effectiveness were: (1) independent variables of team organization characteristics, such as communication, organizational atmosphere, leadership and team knowledge, (2) intervening variables of team organization characteristics. such as job autonomy, technological variety, task subjectivity, task feedback and task importance, and(3) the dependent variables of team level effectiveness, such as job satisfaction and commitment to team organization. The gathered data were processed by using the 6.12 version of the statistical program SAS(Statistical Analysis System), and the reliance coefficient of those measured variables was then evaluated as an average of 0.78. The influence of team level effectiveness was analyzed by using multiple regression analysis. These differences in effectiveness were then analyzed on the basis of related mean values, while the differences among demo-sociological characteristics were analyzed by using the dispersion analysis(ANOVA) and the t-test. The results of the study can be summarized by the following. First, regarding the relationship between team organization characteristics and team level effectiveness, all of the factors including communication, organizational atmosphere, leadership and team knowledge were found to have a significant influence on effectiveness. Second, the factors of team job characteristics, such as technological variety, task importance and job autonomy, had significant effects on job satisfaction and organizational commitment among the teams members. Team level effectiveness was generally high, while team job satisfaction was higher the teams organizational commitment. Third, regarding the demo-sociological characteristics, team level effectiveness was found to be higher among those who were older, who had more job experience, and who had a higher position. Comparing the differences among job types, the effectiveness was relatively higher in the fields of nursing and administration/management then in other fields. Further study should be done towards the setting of variables for characteristics of hospital organization, developing suitable methods of measurement, and researching individual level effectiveness.

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Career Choice and Employment Preparation Condition for EMT Students (응급구조(학)과 학생의 취업진로선택 및 취업준비 현황)

  • Park, So-Mi;Choi, Eun-Sook;Kim, Mi-Sook;Lee, Kyoung-Youl
    • The Korean Journal of Emergency Medical Services
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    • v.15 no.1
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    • pp.65-78
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    • 2011
  • Purpose : We investigated the career choice and the employment preparation of emergency medical technology (EMT) students. The results of study will provide the base information about the consciousness for career choice and employment of the EMT students. Method : We conducted 1,586 surveys from 665 students at six four-year colleges and 921 students at seven three-year colleges, from Aug. 27th to Oct. 31st in 2010. The result was analyzed by SPSS 18.0 using description statistics, t-test, ANOVA, Scheffe and Pearson correlation coefficient. Result : The general characteristics showed male 50.2% and female 49.8%, and first grade 34.6%, second grade 27.4%, third grade 28.2%, and fourth grade 9.8%. The 53.9% of students had experienced the hospital training and the 44.8% did the fire station training. For the choice of job, there were the 61.8% student who hope to enter the employ in fire station or public service, while 25.7% students hope to be employed in hospitals. The reason for a wish job were 'majors-related job' in 18.2% students, 'employment stability' in 17.2% and 'hit on the aptitude and talent' in 16.7%, 'appropriate salaries' in 15.9%. In the questionnaire of the University what to assist you for job preparation, they chose the 'support for get major related license', 'support for officer exam preparation' and 'support of foreign language study' in 34.6%, 16.8% and 16.6%, respectively. For achieved licence, they had a driver's license in 53.9%, BLS (basic life support) provider in 20.3%, life guard in 16.2% and scuba in 8.8%. The statistically significant correlation was identified between the awareness of University that provides job information and one's career awareness (r= .203, p<.000), the awareness that University provide job information and one's confidence in employment (r= .236, p<.000), and one's career awareness and one's confidence in employment (r = .356, p = .000). Conclusion : The most of EMT Students are well conscious of the their future employment and has prepared career to be employed their preference job.

The Acupuncture Effect on Juvenile Smoking (청소년에 대한 금연침 효과)

  • Lim, Ho-Jea;Son, Chi-Hyoung;Lee, Won-Hui;Jang, Ha-Jeong;Seo, Joo-Hee;Jung, Kyung-Suk;Moon, Sung-Il
    • Journal of Acupuncture Research
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    • v.23 no.1
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    • pp.53-62
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    • 2006
  • Objectives : Because of the recent well-being syndrome, concerns about smoking cessation, as well as dietary improvement and exercise, are being increased. There are various methods for smoking cessation. Among them, recently acupuncture treatment is verified through diverse attempts. This research was conducted to examine the effects of acupuncture treatment especially on juvenile smoking cessation. Methods : From April 04 to Oct 04, this study had investigated 93 middle and high school students. 5 times of acupuncture treatment were given to each participant, and the survey was executed before and after each treatment. The acupuncture was treated to the ear alternately twice a week. The evaluation was taken before the treatment after the 1st treatment, and the 5th treatment with 6 questions of amount of daily smoking, desire to smoke, taste of smoking, subjective symptoms, smoking cessation proportion, Fagerstorm Tolerance Questionaire point. Results : Regarding amount of daily smoking, the significant tendency between before and after the treatment varied, but between the 1st and the 5th treatment, there was no difference. The 1st treatment had caused desire to smoke reduction in 46 students(49.5%), but the 5th treatment didn't have much effects on desire to smoke(43 persons; 46.2%). After treatment, 37.6% had no effect in taste of smoking, while the rest of them showed various reactions. Also, there were no difference of significant tendency between the 1st and 5th treatments. In respect to the amount of smoking, 70% of them achieved smoking cessation, or reduction in smoking, but about 25% of them showed no changes. Various subjective symptoms such as lethargy, decrease of appetite, headache were shown, and especially desire to smoke was shown pervasively. Regarding Fagerstorm Tolerance Questionaire point, the average of significant tendency in point after the treatment had decreased(3.1+-2.4 to 2.1+-2.1, p<0.0001). but for those students who had tried smoking cessation less than 5 times, Fagerstorm Tolerance Questionaire point had decreased significantly, but for the others who had tried smoking cessation more than 5times, there were no difference. Conclusion : In regard to 6 questions of amount of daily smoking, desire to smoke, taste of smoking, subjective symptoms, smoking cessation proportion, Fagerstorm Tolerance Questionaire point, various conclusion is drawn. These results suggest that acupuncture treatment on juvenile may have the tendency of smoking cessation.

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Soft Tissue Change in Frontal View after Orthognathic Surgery for Class III Malocclusion: Analysis Using Facial 'Phi' Mask (Facial 'Phi' Mask를 이용한 3급 부정교합 환자의 악교정수술 후 정면부 연조직의 변화)

  • Heo, Young-Min;Kim, Hong-Soek;Paeng, Jun-Young;Hong, Jong-Rak;Kim, Chang-Soo
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.33 no.6
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    • pp.490-496
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    • 2011
  • Purpose: Dr. Marquardt made the facial 'phi' mask using golden ratio. Most class III patients have bulky faces and want a smaller face. Using a facial golden mask, this study estimated and compared frontal photographs before and after operation for soft tissue measurement. The golden mask can be considered as a reference tool for facial esthetic analyses especially in lower face. Methods: Forty patients who had undergone orthognathic surgery at Samsung Medical Center from January 2006 to December 2009 were included in this study. These patients had Class III malocclusion. Lateral cephalometric radiographs, frontal clinical photos of pre-op and 8~12 month later post-op, and the facial 'phi' mask using golden ratio, were used for analysis. Reduction of the lower face area, occlusal plane changes, amounts of mandible setback and amounts of maxilla posterior impaction were estimated. Results: Lower facial reduction ratio and mandibular setback amounts were significantly different between 1-jaw and 2-jaw groups. Average postoperative changes in the area of lower face between bilateral sagittal split ramus osteotomy (BSSRO) and BSSRO combined maxilla posterior impaction were compared by using an independent simple t-test and $P$ value was 0.016. Therefore, the lower facial reduction ratio and mandibular setback amount were significantly different in maxilla posterior impaction. Conclusion: The two-jaw surgery group showed more reduction of the lower facial area than the 1-jaw surgery group. The amount of lower facial reduction was more related with the amount of mandibular setback. There was no significant relation in lower facial reduction with amount of maxilla posterior impaction, pre-op occlusal plane, post-op occlusal plane and the mandibular angle. A relationship between the change in the lower facial area and the amount of maxilla posterior impaction or the change of mandibular angle occlusal plane at pre-op could not be found because of the difference in the amount of setback between two groups.

Study on Sensibility of Knit by Structural Design Patterns (편성조직에 따른 니트패턴의 패션감성 연구)

  • Ko, Soon-Young;Park, Myung-Ja
    • Journal of the Korea Fashion and Costume Design Association
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    • v.10 no.3
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    • pp.1-13
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    • 2008
  • The purpose of this research is to study the cause of obstruction in various knit pattern structures by understanding the needs of the customers, and to develop knitted fabric goods that satisfy the individual taste of consumers and that reflecting the latest fashions. Actual conditions of the manufacturer's designing processes must be examined. In addition, a comparison analysis of fashion sensibilities and preferences between producers and consumers had been made in order to study developing knit pattern structures. Questionnaires and interviews had been used as research methods. The research involved two groups: one group consisted of 57 producers, which included designers, programmers, and merchandisers working for a knit manufacturer in Seoul, while the other group consisted of 74 consumers, which included students with knitted fabric design as their major and those who have working knowledge of knitted fabrics. For a more accurate evaluation, 28 out of 150 patterns have been selected through a preliminary study conducted by 24 designers. On the 28 knit patterns, a sensibility evaluation had been made through the use of the sense of sight and sense of touch, which was followed by a frequency analysis, cluster analysis, and t-test using SPSS 12.0. The results are as follows: the fashion sensibility evaluation on knit patterns showed that structures, such as racking II or lace II, are typically elegant ('elegance'), while structures, such as links I or racking I, are typically 'active.' Furthermore, a 'country' image was displayed in structures such as cable I, cable II, and miss II. Links I appeared as 'sophisticated'. Miss I and milano were said to have 'modem' images. Lace II was regarded as 'ethnic', while racking II was said to have a 'romantic' image. 2:1 rib and milano were generally thought to be manly ('manish'). The fashion sensibility scale for each knit pattern has been made based on the above results. Based on producer and consumer responses, the sensibility evaluation on knit pattern structures showed that the two groups had similar preferences in knit pattern structures. Therefore, the fashion sensibility scale developed in this study can be used as a basic data for structure development when designing knitted fabric goods.

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Experimental Studies on the Structural Safety of Pipe-Houses (파이프하우스의 구조안전에 관한 실험적 연구)

  • 김문기;남상운
    • Journal of Bio-Environment Control
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    • v.4 no.1
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    • pp.17-24
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    • 1995
  • This study was carried out to make fundamental data for structural safety test of pipe- houses. Experiment on the stress distribution of pipe- houses was conducted to find suitable structural analysis model by examination of end support conditions of pipe. Besides, the loading test and the pile driving test were done to find pull-out capacity and bearing capacity of pipe on the assumption that pipe is pile foundation. For single span pipe - house, the theoretical results assuming the end support condition of pipe is fixed under ground agreed closely with the experimental results of stress distribution. On the other hand for double span pipe -house, the end support conditions of pipe were fixed support when vertical load is applied, and hinged one when horizontal load is applied. The pull - out capacity and allowable bearing capacity of the pipe portion that was buried in the grounds that were soft soil of paddy field and medium or hard soils of dry field derived from experimental results.

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Relationship between Blood Stasis and Arterial Stiffness in the Patient with Ischemic Stroke (뇌경색 환자의 어혈변증과 동맥경직도의 관련성 연구)

  • Shin, Won-Jun;Park, Young-Min;Jeong, Dong-Won;Hong, Jin-Woo;Sun, Jong-Joo;Lee, Jun-Woo;Jung, Woo-Sang;Park, Seong-Uk;Moon, Sang-Kwan;Park, Jung-Mi;Ko, Chang-Nam;Cho, Ki-Ho;Kim, Young-Suk
    • The Journal of Korean Medicine
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    • v.27 no.3 s.67
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    • pp.241-250
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    • 2006
  • Backgrounds: Blood stasis is hon as an important pathologic factor for vascular disorder in Oriental medicine. Despite its clinical importance there have been few objective tests for diagnosing blood stasis. Objectives: This study was designed to examine the relationship between blood stasis and arterial stiffness measured by cardio-ankle vascular index (CAVI). Methods: The subjects were 104 ischemic stroke patients with onset after 14 days. Their general characteristics, lipid profiles and uric acid were recorded. The degree of arterial stiffness was assessed by CAVI, and blood stasis was evaluated by diagnostic criteria. The data were analyze4 by chi-square test, student t-test, spearman correlation analysis, and pearson correlation analysis. Then, stepwise multiple logistic regression analysis was applied in order to exclude the interactions among several factors. Results: There were significant differences in right, left and higher CAVI between the blood stasis group and the non blood stasis group (p-value<0.01). Age, systolic blood pressure, triglyceride and CAVI had relationships with blood static scores. In multiple logistic regression analysis, the adjusted odds ratio of blood stasis for arterial stiffness with CAVI above 9 were 7.091 (95% confidence interval, $1.641\sim30.638$). Conclusions: The results demonstrated the relationship between blood stasis and arterial stiffness measured by CAVI. Therefore, we suggest that CAVI should be one of the objective tests for diagnosing blood stasis.

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The Stress Coping Strategies and Cognitive Characteristics of Somatic Symptom Perception in Patients with Panic Disorder (공황장애 환자의 스트레스 대처방식과 신체 증상 지각에 대한 인지적 특성)

  • Jung, Hae-Won;Lee, Moo-Suk;Park, Woo-Young;Yang, Jong-Chul;Lim, Eun-Sung;Park, Tae-Won;Chung, Yong-Chul;Chung, Sang-Keun;Hwang, Ik-Keun
    • Anxiety and mood
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    • v.3 no.2
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    • pp.116-122
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    • 2007
  • Objective : The purpose of this study was to investigate the strategies used to cope with stress and the cognitive characteristics of somatic symptom perception in patients with panic disorder. Methods : A total of 101 patients who met the DSM-IV criteria for panic disorder and 60 normal controls were recruited for participation in this study. We evaluated the subjects using The Way of Stress Coping Questionnaire (SCQ), Somato-Sensory Amplification Scale (SSAS), Symptom Interpretation Questionnaire (SIQ), and the Panic Disorder Severity Scale (PDSS). We analyzed the data using an independent t-test and Pearson correlation analysis (p<0.05). Results : The patients who used emotionally focused coping strategies scored significantly lower on the SCQ. The patients with panic disorder showed greater amplification of body sensations in the SSAS, a significantly higher score on the physical interpretation subset of the SIQ, and a lower score on the environmental interpretation subset of the SIQ than the normal controls. The PDSS scores were positively correlated with the SSAS score and physical interpretation score on the SIQ. Conclusion : These results show that patients with panic disorder have poor emotionally focused strategies for coping with stress, greater amplification of body sensations, and a tendency towards a physical interpretation of somatic symptoms.

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A Study on the Satisfaction and Achievement of Learning by Female Learner's Characteristics in Internet Education Program (여성 학습자의 특성에 따른 인터넷교육 프로그램 만족도와 학업성취도에 관한 연구)

  • Lim, Kwang Myung;Kim, Sung Soo
    • Journal of Agricultural Extension & Community Development
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    • v.8 no.1
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    • pp.25-40
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    • 2001
  • The purposes of the study were to identify satisfaction and achievement of learning by female learner's characteristics, and to suggest measures to improve quality of education in internet education programs. In order to determine the educational effectiveness associated with the characteristics of learners, this study attempted to employ two way approaches by observing the degree of achievement for learning, which represents an instructor-oriented approach, and the degree of satisfaction for education, which represents a learner-oriented approach to enhance the quality of internet education for female learners. As an approach to evaluate the educational effectiveness, the degree of achievement in learning(Tyler's classical approach), and the degree of satisfaction for education (Scriven's consumer-oriented evaluation model) were utilized. A survey form was developed by the researcher after reviewing the various tools originated from Boshier, Cross, Gagne and Choi, and distributed to a panel of judges that examined the content validity of the instrument. The sample for the study consisted of 160 female learners from three universities in Seoul and capital area, and the survey form was used to collect data for this study. The SPSS WIN program was used in analyzing the data and a series of statistical tests were conducted including frequency, percentile, t-test, ANOVA, correlation, multiple regression, and factor analysis. The statistical significance level was 0.05. The following conclusion were drawn from this study of female internet education. First, it was evident that female internet learners tend to utilize information from internet, and this can be interpreted as participants' positive attitude, and voluntary participation. Second, educational facilities and services should be improved in the future, because the level of satisfaction was low in these areas compared to curriculum and educational methodology. Third, the participating factors influenced by the level of satisfaction for education of learner characteristics were the 'formation of inter-personal relationship and willingness to change' and the 'needs for education on internet', thus appeared that both social and educational needs influenced the level of satisfaction for education. Fourth, the degree of achievement in learning was higher in the order of 1) attitude 2) function 3) knowledge, thus, attitude change was the most important in achievement of learning. Fifth, the individual background that influenced the level of achievement in learning were age and educational experience. As for the individual level of achievement for learning, the younger and more educated group were more satisfied.

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