• Title/Summary/Keyword: 3-thiophenecarboxylic acid:thiophene

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Fabrication of enzymatic biosensor based on the poly(3-thiophenecarboxylic acid-co-thiophene) polymer as electron-transfer materials

  • Kim, Soo-Yeoun;Jo, Hyeon-Jin;Choi, Seong-Ho
    • Journal of the Korean Applied Science and Technology
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    • v.36 no.1
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    • pp.269-278
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    • 2019
  • We fabricated glucose oxidase (GOx)-modified biosensor for detection of glucose by physical immobilization of GOx after electrochemical polymerization of the conductive mixture monomers of the 3-thiophenecarboxylic acid (TCA) and thiophene (Th) onto ITO electrode in this study. We confirmed the successfully fabrication of GOx-modified biosensor via FT-IR spectroscopy, SEM, contact angle, and cyclic voltammetry. The fabricated biosensor has the detection limit of $0.1{\mu}M$, the linearity of 0.001-27 mM, and sensitivity of $38.75mAM^{-1}cm^{-2}$, respectively. The fabricated biosensor exhibits high interference effects to dopamine, ascorbic acid, and L-cysteine, respectively. From these results, the fabricated GOx-modified biosensor with long linearity and high sensitivity could be used as glucose sensor in human blood sample.