• Journal of Life Science
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• v.33 no.7
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• pp.531-537
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• 2023

Intracellular and axonal transport is mediated by microtubule-dependent motor proteins, such as kinesins and cytoplasmic dynein. Kinesin moves along the microtubule to the positive end of the microtubule, while dynein moves to the negative end of the microtubule. Kinesin-1 was first identified as a kinesin superfamily protein (KIF) that functions in the intracellular transport of various cargoes, including organelles, neurotransmitter receptors, and mRNA-protein complexes, through interactions between the carboxyl (C)-terminal domain and the cargo. It interacts with other cargoes, but the adapter/scaffold proteins that mediate between kinesin-1 and the cargo have yet to be fully identified. In this study, a yeast two-hybrid screen was used to identify adapter proteins that interact with the C-terminal region of KIF5A. We found an association between the C-terminal region of KIF5A and the cyclin-dependent kinase 2-associated protein 1 (CDK2AP1), originally identified in malignant hamster oral keratinocytes. CDK2AP1 bound to the C-terminal region of KIF5A and did not interact with KIF3A (the motor of kinesin-2), KIF5B, KIF5C, and kinesin light chain 1 (KLC1). The C-terminal region of CDK2AP1 is essential for its interaction with KIF5A. When co-expressed in HEK-293T cells, CDK2AP1 and kinesin-1 co-immunoprecipitated and co-localized in the cells. These results suggest that the KIF5A-CDK2AP1 interaction serves as an adapter protein connecting kinesin-1 and the cargo when kinesin-1 transports cargo in cells.

• KIISE Transactions on Computing Practices
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• v.22 no.3
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• pp.133-138
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• 2016

Motion detection algorithms based on difference image are classified into background subtraction and previous frame subtraction. 1) Background subtraction is a convenient and effective method for detecting foreground objects in a stationary background. However in real world scenarios, especially outdoors, this restriction, (i.e., stationary background) often turns out to be impractical since the background may not be stable. 2) Previous frame subtraction is a simple technique for detecting motion in an image. The difference between two frames depends upon the amount of motion that occurs from one frame to the next. Both these straightforward methods fail when the object moves very "slightly and slowly". In order to efficiently deal with the problem, in this paper we present an algorithm for motion detection that incorporates "reflected light area" and "difference image". This reflected light area is generated during the frame production process. It processes multiplex difference image and AND-arithmetic of bitwise. This process incorporates the accuracy of background subtraction and environmental adaptability of previous frame subtraction and reduces noise generation. Also, the performance of the proposed method is demonstrated by the performance assessment of each method using Gait database sample of CASIA.

• Journal of Advanced Marine Engineering and Technology
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• v.33 no.8
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• pp.1180-1186
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• 2009

This experimental study is about the flow characteristics according to existence and nonexistence of the control rod and location in the flow field where it has the Inclined rear walls in the open cavity. By using the visualization of flow and particle image velocimetry (PIV), we performed about a change and speed of the Reynolds number. Our objective was what part of the control rod gives less effects to the characteristics of flow and how the shear mixing layer moves at what critical point of the Reynolds number. As a result, we differed the location of control rod. So finally, L/H=0.2 was discovered to give less effects to the cavity. The flow of backside of vortex faces the upper side. And we found that this phenomenon shows up more clear when the number of Reynolds increases. This is because of the flow of vortex causes by the condition of y/H=1.0. This phenomenon gets more clear with increasing of number of Reynolds, and critical point of the Reynolds number was $Re=1.0{\times}10^4$ around. If control rod is L/H=0.1, depending on the number of Reynolds ($Re=6.0{\times}10^3$, $Re=8.0{\times}10^3$, $Re=1.0{\times}10^4$, $Re=1.2{\times}10^4$), doubled vortex shows up. As the shear mixing layer of the upper side of cavity increases, the speed of the lower side was very stable.

• Journal of the Korean earth science society
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• v.34 no.4
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• pp.289-302
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• 2013

In order to determine the provenance of the Huksan Mud Belt sediments in the southeastern Yellow Sea, the major and rare earth elements of the same sediments were analyzed. The surface sediments were sampled from top of piston-cores and box-cores taken at 51 sites within the Huksan Mud Belt. With the mean grain size of $5-6{\phi}$, the sediments of the study area are mud-dominated. The spatial distribution patterns show that silt content is high in the northern Mud Belt, whereas clay content increases as it moves toward the southern Mud Belt. Interestingly, the geochemical compositions both of major and rare earth elements have resulted in differences of sediment provenance. Among the major elements, plots of Fe/Al vs. Mg/Al ratios, $Al_2O_3$ vs. MgO ratios, and $Al_2O_3$ vs. $K_2O$ reveal that the Huksan Mud Belt sediments are dominated by the Korean river-derived sediments. However, the characteristics of rare earth elements infer sediments originating from the Chinese rivers. This discrepancy between the above provenances is attributed to the different contributory factors in the content of chemical elements. Considering strong correlation between major elements with grain sizes, the contents of the major elements are thought to be influenced by the grain size. However, there is a weak correlation between rare earth elements and grain sizes. The behaviour of rare earth elements may be controlled by heavy minerals, rather than grain sizes. Further study requires to solve the discrepancy arose from the difference in applied chemical tracers.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.38 no.3
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• pp.234-240
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• 2002

The static stability of the otter board in relation to the angle of attack ($\alpha$) was studied analytically and experimentally from the moments of tensions and hydrodynamic force acting on it. Three flat plates of 0.5, 1.0, and 1.5 aspect ratios (λ) and four cambered plates of 5, 10, 15, and 20% camber ratios (CR) with the same aspect ratio (λ=1.5) were tested in a circulating water tank for measuring the hydrodynamic forces and moments relevant to the position of hydrodynamic center. And, center-of-pressure coefficients ($C_p$) and moment coefficients ($C_M$) of each plate as a function of the angle of attack were calculated for estimating the static stability from hydrodynamic forces. The obtained results are summarized as follows ； 1． When the angle of attack for otter board is changed from equilibrium for some reason, moments depending upon tensions of warp and sweep line always act in order to have the static stability, respectively. 2. Position of center-of-pressure of each flat plate moves from leading edge to center of plate with the increase of the angle of attack. It means that the moment of hydrodynamic force acting on flat plates also increases the static stability of plate. 3. With the increase of the angle of attack for cambered plates, the positions of center of-pressure move from trailing to leading edge, and then turn toward center of plate. As the camber ratios increase, the ranges of the angle of attack of the static un stability depending on moment of hydrodynamic force become wide.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.2
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• pp.33.1-33.1
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• 2016

We report detection of short-term flux variability in multi-epoch observations and intraday variability in polarized emission at millimeter-wavelength from S5 0716+714 using Korean VLBI Network (KVN) radio telescopes. Over the whole observation epochs, the source shows significant inter-month variations at K- and Q-band with modulation indices of 19% at K-band and 36% at Q-band. In each epoch, the source shows monotonic flux increase in Epoch 1 and 3, and monotonic flux decrease in Epoch 2 and 4. We found an inverted spectrum with mean spectral indices of -0.57 in Epoch 1 and -0.15 in Epoch. On the contrary, we found relatively steep indices of 0.24 and 0.17 in Epoch 2 and Epoch 4, respectively. In the study of intraday variability of polarization, we found significant variations in the degree of linear polarization at 86 GHz, and in polarization angle at 43 and 86 GHz during ~10 h. The spectrum of the source is quite flat with spectral indices of -0.07 to 0.07 at 22-43 GHz and -0.23 to 0.04 at 43-86 GHz. The measured degree of the linear polarization ranges from 2.3% to 3.3 % at 22 GHz, from 0.9% to 2.2 % at 43 GHz and from 0.4 % to 4.0 % at 86 GHz, yielding prominent variations at 86 GHz over 4-5 h. The linear polarization angle is in the range of 4 to $12^{\circ}$ at 22 GHz, -39 to $81^{\circ}$ at 43 GHz, and 66 to 119 at 86 GHz with a maximum rotation of $110^{\circ}$ at 43 GHz over ~4 h. We estimated the Faraday rotation measures (RM) ranging from -9200 to 6300 rad m-2 between 22 and 43 GHz, and from -71000 to 7300 rad m-2 between 43 and 86 GHz, respectively. The frequency dependency of RM was investigated, yielding a mean power-law index, a, of 2.0. This implies that the polarized emission from S5 0716+714 at 22-86 GHz moves through a Faraday screen in or near the jet of the source.

• Proceedings of the KWS Conference
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• 2010.05a
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• pp.51-51
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• 2010

Recently just as in the automobile industry, shipbuilders also try to reduce material consumption and weight in order to keep operating costs as low as possible and improve the speed of production. Naturally industry is ever searching for welding techniques offering higher power, higher productivity and a better quality. Therefore it is important to have a details research based on the various welding process applied to steel and other materials, and to have the ability both to counsel interested companies and to evaluate the feasibility of implementation of this process. Submerged-arc welding (SAW) process is usually used about 20% of shipbuilding. Similar to gas metal arc welding(GMAW), SAW involves formation of an arc between a continuously-fed bare wire electrode and the work-piece. The process uses a flux to generate protective gases and slag, and to add alloying elements to the weld pool and a shielding gas is not required. Prior to welding, a thin layer of flux powder is placed on the work-piece surface. The arc moves along the joint line and as it does so, excess flux is recycled via a hopper. Remaining fused slag layers can be easily removed after welding. As the arc is completely covered by the flux layer, heat loss is extremely low. This produces a thermal efficiency as high as 60% (compared with 25% for manual metal arc). SAW process offers many advantages compared to conventional CO2 welding process. The main advantages of SAW are higher welding speed, facility of workers, less deformation and better than bead shape & strength of welded joint because there is no visible arc light, welding is spatter-free, fully-mechanized or automatic process, high travel speed, and depth of penetration and chemical composition of the deposited weld metal. However it is difficult to application of thin plate according to high heat input. So this paper has been focused on application of the field according to SAW process for thin plate in ship-structures. For this purpose, It has been decided to optimized welding condition by experiments, relationship between welding parameters and bead shapes, mechanical test such as tensile and bending. Also finite element(FE) based numerical comparison of thermal history and welding residual stress in A-grade 3.2 thickness steel of SAW been made in this study. From the result of this study, It makes substantial saving of time and manufacturing cost and raises the quality of product.

• Journal of Dental Rehabilitation and Applied Science
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• v.26 no.4
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• pp.477-482
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• 2010

In a case of multiple posterior teeth loss, antagonistic teeth extrude to the edentulous space and compensatory occlusion on the remained anterior teeth leads to occlusal trauma. Extrusion of antagonistic teeth breaks down occlusion plane and loss of posterior support bring about severe wear of remained teeth. In this situation, it is needed to restore remained teeth and edentulous space by increasing vertical dimension to obtain prosthodontic rehabilitation space and to correct occlusion plane. In this case report, the patient had a masticatory problem with loss of posterior teeth support and an esthetic problem of shortened anterior teeth. Before the tooth preparation for the prosthodontic restoration, the patient used removable device for 2 months to increase vertical dimension reversibly. After that, he got provisional fixed restoration with irreversible tooth reduction and used it for 3 months. It had spent 5 month to evaluate the adaptation state on final restoration with incresed vertical dimension. The increasing amount was 3 mm, which was relatively in less degree and masticatory system adapted to the increased vertical dimension without any pathologic changes. Final restoration was made to have equal-intensity contacts on all teeth in a verifiable centric relations and immediate disclusion of all posterior contacts the moment the mandible moves in any direction from centric relation. In addition, metal occlusion surface on posterior teeth was applied to prevent excessive muscle activation, occlusal trauma and the porcelain fracture.

• The Journal of Engineering Geology
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• v.21 no.2
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• pp.125-131
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• 2011

The discharge characteristics of the Seodo Mulgol Spring-the only groundwater-producing area in Dokdo-were evaluated by measurements of discharge rate and electrical conductivity (EC) on five occasions. The Seodo Mulgol Spring is fed by rainfall in upstream areas of the Mulgol cave, and the rainwater of the area moves down along cooling joints developed in trachyandesite II and trachyte, finally discharging at the Mulgol cave. The discharge rate of the Seodo Mulgol Spring varied from 1.12 to 7.02 $m^3/d$ during the study period and EC varied from 2,650 to 3,390 ${\mu}S/cm$, showing a sharp increase during heavy rainfall. The observed variations in discharge rate and EC at the Seodo Mulgol Spring are attributed to the relatively short distance between the recharge area and the Mulgol cave, and to the rapid movement of groundwater through columnar joints developed in trachyandesite II and trachyte. Additional discharge measurements, combined with precise rainfall data, are required at Dokdo to elucidate the discharge characteristics of the Seodo Mulgol Spring.

• The Journal of the Korea institute of electronic communication sciences
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• v.17 no.3
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• pp.537-542
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• 2022

There is a limit to the current indoor air quality (IAQ) monitoring method using fixed sensors and devices. A mobile robot for IAQ monitoring was developed by mounting IAQ monitoring sensors on a small multi-legged robot to minimize vibration and protect the sensors from vibration while robot moves. The developed mobile robot used a simple gait mechanism to enable the robot to move forward, backward, and turns only with the combination of forward and reverse rotation of the two DC motors. Due to the simple gait mechanism, not only IAQ data measurements but also gait motion control were processed using a single Arduino board. Because the mobile robot has small number of electronic components and low power consumption, a relatively low-capacity battery was mounted on the robot to reduce the weight of the battery. The weight of mobile robot is 1.4kg including links, various IAQ sensors, motors, and battery. The gait and turning speed of the mobile robot was measured at 3.75 cm/sec and 14.13 rad/sec. The maximum height where the robot leg could reach was 33 mm, but the mobile robot was able to overcome the bumps up to 24 mm.