• The Journal of Korean Medicine
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• v.20 no.3 s.39
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• pp.36-44
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• 1999

Objectives: It has been well known that electroacupuncture(EA) has an analgesic effect and there is a pain control system in the central nervous system(CNS). The pain control system is composed of three major nuclei, which are periaqueductal gray(PAG), raphe nuclei, and the pain inhibitory complex located in the spinal cord. It has been suggested that the analgesic effect of EA might be the result of activation of the pain control system in the CNS. However, there may be a possibility that other nuclei are also involved in this pain modulation. Thus, we investigated whether the posterior intralaminar thalamic nuclei (PTIN) are involved in the pain modulation. Methods: To measure the level of pain, the jaw opening reflex (JOR) was used as a pain index. The magnitude of JOR is estimated by averaging the area of 10 successive responses. JOR was evoked by tooth-pulp stimulation with bipolar electrode carrying stimulus with the following parameters: intensity ranging from 420uA to 680ulA, 0.3ms duration of square pulse, and 0.5 Hz. Hapkog($LI_4$) and Taechung ($LR_3$) were the chosen acupoints. The Hapkog point was stimulated ipsilaterally at 5V, 3 Hz, for 15min in total, and the Taechung was stimulated at 2-3 V, 3 Hz, and for a total of 15 or 30 minutes. Different intensities of stimulation were given the PITN; one was given at $300{\mu}A$ and the other was at 500uA. The position stimulated in these nuclei by Paxinos Atlas was AP; from bregma $-4.0{\sim}-4.3mm,\;L; 0.5{\sim}1.8mm,\;D;\;4.8{\sim}6.3mm$. Results: The Hapkog point had a significant analgesic effect (P<0.05). However, the Taechung point had no effect. Both types of stimulation in the PITN did not reveal any analgesic effects. Conclusions: From these results, it was suggested that the posterior intralaminar thalamic nuclei are not involved in the modulation of pain.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.2
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• pp.76-80
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• 2007

In this paper, the PAE (Power Added Efficiency) and the linearity of the Doherty amplifier has been improved using dual bias control and PBG (Photonic BandGap) structure. The PBG structure has used to implement on output matching circuit and dual bias control has applied to improve the PAE of the Doherty amplifier at a low input level by applying it to a carrier amplifier. The Doherty amplifier using the proposed structure has improved PAE by 8% and 5dBc of IMD3 (3rd Inter-Modulation Distortion) compared with those of the conventional class AB amplifier. In addition to, it has been evident that the designed the structure has showed more than a 30% increase in PAE for flatness over all input power level.

• Proceedings of the KIPE Conference
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• 2014.11a
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• pp.187-188
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• 2014

본 논문에서는 3-레벨 NPC(Neutral Point Clamped) 인버터에서 상단 커패시터 전압과 하단 커패시터의 전압의 불균형 시 나타나는 출력 상전류 왜곡에 대한 보상기법에 대하여 제안한다. 스위칭 기법은 SVPWM(Space Vector Pulse Width Modulation)을 사용하였고 상단 커패시터 전압과 하단 커패시터 전압의 불균형이 DC-Link 전압의 0% 15% 35%일 때의 보상 전과 보상 후를 비교 분석 하여 시뮬레이션으로 출력 상전류 보상기법을 검증하였다.

• Proceedings of the IEEK Conference
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• 2000.11b
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• pp.152-155
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• 2000

Oversampling modulators based on high-order sigma-delta modulation provide an effective means of achieving high-resolution A/D conversion in a VLSI technology. Because high-order noise shaping great]y reduces the quantization noise in the signal band. This paper introduces a third-order cascaded sigma-delta modulator that is stable for large input level. Modulator was simulated 3.3V single power supply voltage in 0.65$\mu\textrm{m}$ CMOS technology. It achieves 80㏈ SNR for a 20㎑ input signal bandwidth. A lock frequency is 3㎒ that is 80 oversampling ratio.

• Proceedings of the KIPE Conference
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• 2017.07a
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• pp.229-230
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• 2017

본 논문은 단상 3레벨 PFC 컨버터에 적용하는 두 가지 모듈레이션 기법에 따른 시스템 효율 및 스위치 발열을 비교하고, 열해석 시뮬레이션을 통한 열 분포에 대한 결과를 기반으로 적절한 방열기법 모색을 위한 근거자료를 제시한다. 제안하는 모듈레이션 기법을 통해, 주 스위치인 SiC MOSFET의 도통손실을 저감하여 시스템 효율을 향상시키며, 스위치에 발생하는 열을 저감시킨다. 앤시스 열해석 시뮬레이션을 통해 이를 확인하고, 실험을 통해 검증한다. 정격부하(5kW)에 대해 약 $27^{\circ}C$의 스위치 온도저감이 이루어졌으며, 전 부하(0.5kW ~ 5kW)에 걸쳐 약 1%의 효율이 향상되었음을 실험을 통해 확인하였다.

• Proceedings of the KIPE Conference
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• 2014.07a
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• pp.508-509
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• 2014

전력변환장치의 효율을 개선하기 위해 많은 연구가 이루어지고 있는 가운데, 본 논문에서는 3-레벨 인버터 중에서도 NPC 인버터와 T-타입 인버터를 사용한다. 각 인버터는 서로 다른 스위치 정격에 의해 손실 차이가 생기며, 또한 손실에 영향을 미치는 MI(Modulation Index), PF(Power Factor), 그리고 스위칭 주파수에 따라 손실의 크기가 좌우 되었다. 하지만 두 인버터는 각 구조의 특성상 NPC 의 경우 도통손실이 매우 크며, T-타입의 경우 스위칭 손실이 크게 나타난다는 모듈상의 한계가 있다. 본 논문에서는 인버터 구조에 따라 손실에 지배적으로 영향을 미치는 각 Device의 특성을 고려하여, 전력변환장치에서 발생되어지는 도통손실과 스위칭손실을 분석 하였다.

• Proceedings of the KIPE Conference
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• 2019.07a
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• pp.260-262
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• 2019

본 논문은 철도 차량용 보조전원 장치의 부피 저감을 위하여 펄스 폭 제어가 포함된 공진형 LLC 컨버터를 제안한다. 철도 차량용 보조전원 장치는 가선에 연결되어 객차의 각종 전원을 공급하는 장치로써 객실 내의 전원과 절연이 필수적이다. 따라서 고효율의 절연형 DC/DC 컨버터인 LLC 컨버터가 적용되어 있으나, 가선의 큰 입력전압 변동에 대응하기 위해 스위칭 주파수의 변조 폭이 넓어질 뿐 아니라 제어 난도가 증가하는 단점을 가진다. 이러한 LLC 컨버터의 단점을 보완하기 위해 Boost+LLC 또는 Buck+LLC 컨버터의 두 단계의 전력변환을 통해 Boost 또는 Buck 컨버터가 LLC 컨버터의 입력전압을 제어하며, LLC 컨버터는 항상 공진 주파수에서 동작하도록 제어하는 시스템이 주로 사용된다. 본 논문은 3레벨 LLC 컨버터에 펄스 폭 변조를 적용하여 입력전압 제어를 달성하며, 이를 통해 기존의 시스템보다 부피 저감을 달성하는 방안을 제안한다. 제안된 방법은 전력변환 모의해석 프로그램인 PSIM 및 Matlab을 통해 검증되었다.

• Korean Journal of Optics and Photonics
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• v.20 no.3
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• pp.143-147
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• 2009

We propose an asymmetrical 2.5 Gbps / 622 Mbps bidirectional optical subscriber network with Manchester coded downstream and NRZ (Non-Return-to-Zero) upstream remodulation. The proposed system has important characteristics in the optical network unit (ONU): it does not require a light source or the usual control circuits such as wavelength control and output power control, and it is possible to use a synchronization scheme between upstream and downstream data. We theoretically analyze BER(Bit Error Rate) performance of upstream data remodulated with Manchester coded downstream according to the types of NRZ downstream data and perform simulations with MATLAB. The BER performance and the receiver sensitivity have been improved by 3 dB by adjusting threshold levels compared to the conventional receiver. The results have shown the remodulation scheme with Manchester coded downstream could be a useful technology for asynchronous and asymmetric optical subscriber networks with low cost and simple structures.

• Journal of Power Electronics
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• v.18 no.3
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• pp.702-713
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• 2018

Power loss reduction and total harmonic distortion(THD) minimization are two important goals of improving three-level inverters. In this paper, an optimized pulse width modulation (PWM) strategy that can reduce switching losses and balance the neutral point with an optional THD of three-level neutral-point-clamped inverters is proposed. An analysis of the two-level discontinuous PWM (DPWM) strategy indicates that the optimal goal of the proposed PWM strategy is to reduce switching losses to a minimum without increasing the THD compared to that of traditional SVPWMs. Thus, the analysis of the two-level DPWM strategy is introduced. Through the rational allocation of the zero vector, only two-phase switching devices are active in each sector, and their switching losses can be reduced by one-third compared with those of traditional PWM strategies. A detailed analysis of the impact of small vectors, which correspond to different zero vectors, on the neutral-point potential is conducted, and a hysteresis control method is proposed to balance the neutral point. This method is simple, does not judge the direction of midpoint currents, and can adjust the switching times of devices and the fluctuation of the neutral-point potential by changing the hysteresis loop width. Simulation and experimental results prove the effectiveness and feasibility of the proposed strategy.

• Archives of Pharmacal Research
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• v.28 no.3
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• pp.311-318
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• 2005

Oxidative stress has been reported to elevate ceramide level during cell death. The purpose of the present study was to modulate cell death in relation to cellular glutathione (GSH) level and GST (glutathione S-transferase) expression by regulating the sphingolipid metabolism. LLC­PK1 cells were treated with H$_2$O$_2$ in the absence of serum to induce cell death. Subsequent to exposure to H$_2$O$_2$, LLC-PK1 cells were treated with desipramine, sphingomyelinase inhibitor, and N-acetylcysteine (NAC), GSH substrate. Based on comparative visual observation with H202-treated control cells, it was observed that 0.5 $\mu$M of desipramine and 25 $\mu$M of NAC exhibited about 90 and $95\%$ of cytoprotection, respectively, against H$_2$O$_2$-induced cell death. Desipramine and NAC lowered the release of LDH activity by 36 and $3\%$ respectively, when compared to $71\%$ in H$_2$O$_2$-exposed cells. Cellular glutathione level in 500 $\mu$M H202-treated cells was reduced to 890 pmol as compared to control level of 1198 pmol per mg protein. GST P1-1 expression was decreased in H$_2$O$_2$-treated cells compared to healthy normal cells. In conclusion, it has been inferred that H$_2$O$_2$-induced cell death is closely related to cellular GSH level and GST P1-1 expression in LLC-PK1 cells and occurs via ceramide elevation by sphingomyelinase activation.