• Korean Journal of Exercise Nutrition
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• v.25 no.3
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• pp.28-35
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• 2021

[Purpose] As Panax ginseng C. A. Meyer (ginseng) exhibits various physiological activities and is associated with exercise, we investigated the potential active components of ginseng and related target genes through network pharmacological analysis. Additionally, we analyzed the association between ginseng-related genes, such as the G-protein-coupled receptors (GPCRs), and improved exercise capacity. [Methods] Active compounds in ginseng and the related target genes were searched in the Traditional Chinese Medicine Database and Analysis Platform (TCMSP). Gene ontology functional analysis was performed to identify biological processes related to the collected genes, and a compound-target network was visualized using Cytoscape 3.7.2. [Results] A total of 21 ginseng active compounds were detected, and 110 targets regulated by 17 active substances were identified. We found that the active compound protein was involved in the biological process of adrenergic receptor activity in 80%, G-protein-coupled neurotransmitter in 10%, and leucocyte adhesion to arteries in 10%. Additionally, the biological response centered on adrenergic receptor activity showed a close relationship with G protein through the beta-1 adrenergic receptor gene reactivity. [Conclusion] According to bioavailability analysis, ginseng comprises 21 active compounds. Furthermore, we investigated the ginseng-stimulated gene activation using ontology analysis. GPCR, a gene upregulated by ginseng, is positively correlated to exercise. Therefore, if a study on this factor is conducted, it will provide useful basic data for improving exercise performance and health.

• Journal of Korean Biological Nursing Science
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• v.4 no.2
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• pp.139-150
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• 2002

The purpose of this study was to examine the effect of stretching exercise on quality of life, depression, total cholesterol in the elderly. The one group pre-post test quasi-experimental design was used. 22 subjects were selected from elderly in G-city. The experimental group. The data were collected from April, 2002 to June, 19, 2002, and analyzed by frequency, t-test using SPSS/PC program. The results of this study were summarized as follows ; 1) The quality of life didn't show significant improvement by stretching exercise(t=-1.734, p=0.097). 2) The depression didn't show significant improvement by stretching exercise(t=-0.200, p=0.843). 3) The total cholesterol didn't show significant improvement by stretching exercise(t=-1.050, p=0.083).

• Journal of Digital Convergence
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• v.12 no.3
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• pp.317-323
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• 2014

This research has a purpose of providing base data to prevent musculoskeletal disorders, by analyzing the changes in muscle body due to sling exercises, of the industrial laborers with work-related musculoskeletal disorders. The subjects of this research are 20 volunteers who applied for musculoskeletal treatment exercises in hospitals, from region D industry H. 10 of the 20 subjects were involved in sling exercise program for 12 weeks, and the other 10 subjects were ordered to retain their common practices. We have used the statistics software SPSS ver.18.0 to analyze the data, and have offered a descriptive analysis of the measured variables. To discover the sling exercise effects, we have executed a t-test (paired sample t-test) comparing the before-after relationship of 12-week sling exercise program, and the level of significance were set to a=.05. With these set of research methods and procedures, we have concluded the following. As a result, we have concluded that 12-week sling exercise program does exert influence in changing muscle body of work-related musculoskeletal patients.

• Journal of Korean Academy of Nursing
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• v.28 no.4
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• pp.941-957
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• 1998

The purpose of this study was to use meta-analysis to analyze result of 17 studies which investigated the effects of integrated programs, and 11 studies which examined the effects of exercise programs on pain, depression, and disability. The 28 studies analyzed in this work were selected from the following sources. MEDLINE Search, bibliographies of related studies, main academic journals of nursing in Korea, and journals on arthritis issues. For the analysis of the data, homogeniety of effect sizes which were calculated based on data in the 28 studies was tested and its average effect size was computed by using meta analysis software package which was developed by Song(1992, 1998). The results can be summarized as follows : 1) Homogeneity tests were conducted on integrated programs on pain. In the prelimiary homogeneity tests on effect size of all 17 studies, no homogeneity was found. When homogeneity tests on the effect size of the remaining 15 studies were performed, excluding two studies which had extremely larger effect size compared to other studies, the 15 studies were found to be homogeneous(Q=16.38, p=.23). The obtained average effect size, D(Mean Standardized Difference Between Means), was .25. When homogeneity tests on effect size on pain was conducted for the excercise programs, effect size for all nine studies were found to be homogeneous (Q=7.42, p=.49) and the average effect size D=.30. Therefore, Hypothesis 1 was rejected from the results, that an average effect size of the integrated programs on pain was not significantely different from that of the exercise programs on pain. 2) Since only two studies investigated the effect of exercise programs on depression, comparison between the average effect size of integrated programs and that of exercise programs on depression could not be conducted, and hypothesis 2 could not be tested. Thereby, only the average effect size of integrated programs on depression was obtained. Eight studies were tested to be positive on the homogeneity of effect sizes(Q=18.31, p=.02) at $\alpha$<.01 and its average effect size was D=.11. 3) For the analysis of integrated program on disability, 13 studies, except for four which had an extremely large effect size compared to the others were found to be homogeneous at $\alpha$<.01 (Q=22.30, p=.04) and the average effect size on disability was D=.16. For analysis of the exercize programs on disability, eight studies, except for one which had an extremely large effect size compared to others, were found to be homo geneous(Q=7.87, p=.34) and the average effect size on disability was D=.60. Therefore, Hypothesis 3 was accepted from the results that an average effect size of exercise programs on disability was significantly larger than that of integrated programs on disability.

• Journal of Korean Academy of Rural Health Nursing
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• v.6 no.1
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• pp.5-14
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• 2011

Purpose: The primary goal of this study was to develop a case management with exercise program for community dwelling elders who live alone, and examine the effects of the program. Method: The design of this research was a one group pre-post test study. The participations were 85 elders diagnosed with hypertension and diabetes mellitus and who lived alone as residents of D city. The case management with exercise program included exercise and counseling as the intervention and was provided for 12 weeks. Data were collected before and after the intervention which lasted from September 3 to November 26, 2009. Collected data were analyzed using descriptive statistics, and paired t-test. Results: There were significant differences in blood pressure (t=-5.24, p<.001, t=-1.94, p= .040), fasting blood sugar (t=-4.41, p<.001), ADL (t=-5.43, p=.022) and cognitive function (t=7.41, p=.008) between pre- and post intervention. Conclusion: These results indicate that the case management program is an important intervention for health promotion for community-dwelling elders, and exercise improves functional status of older persons with diseases. Therefore, now is the time to develop new supportive community-based programs for elders who live alone. However, it is also necessary to do further longitudinal studies to confirm the results of this study.

• Journal of Korean Clinical Nursing Research
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• v.17 no.2
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• pp.163-175
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• 2011

Purpose: This study was to analyze the characteristics and effect size of intervention studies applied to cancer-related fatigue in Korea. Methods: For meta-analysis, a total of 963 studies were retrieved from search engines. And 19 studies with a total of 721 participants published from 1990 to 2010 were selected upon their satisfaction with the inclusion criteria. Two authors independently extracted data from the selected studies and assessed the methodological quality. The data was analyzed by the RevMan 5.0 program of Cochrane library. Results: Intervention studies included 4 studies on foot-reflexo-massage (21.1%), comprehensive program (21.1%), and exercise (21.1%), respectively, 3 for hand-reflexo-massage (15.8%), and 4 for others. The effect size of the intervention studies shown higher effect size in order of exercise (d=-1.80), and foot & hand-reflexo-massage (d=-0.55). Conclusion: This study suggest that exercise can reduce the intensity of cancer-related fatigue, even though the number of intervention studies and randomized controlled trials were very few. There is limited evidence that reflexo-massage is effective in reducing cancer-related fatigue.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.9 no.1
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• pp.45-51
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• 2015

This study was to verify effect on muscle strength of trunk and body composition for elderly according to spinal stability exercise with three dimension. We recruited forty elderly participants(twenties as training group, the other twenties as control group) over sixty five aged. The participant performed muscle strength estimation to exercise of eight direction using spinal stability training system. Also, we estimated body composition in participants using inbody 720. Trining group performed direction exercise(F, FOR, R, BOR, B, BOL, L, FOL) and multiple exercise with band exercise, strengthening gym and walking during thirty minute. But control group only performed multiple exercise without direction exercise. All training progressed three days a week for eight weeks. The results showed that muscle strength of trunk in training group increased significantly from 79.9 point to 85.6 point with reducement of body weight, body fat and BMI. However, control group showed a few exercise effect with increasement of amount of muscles and reducement of body fat without muscle strength of trunk. These results means that spinal stability exercise could be helped to prevent obey and fall of elderly caused by muscle strengthening and improving body composition. This could be applied to develop rehabilitation program efficiently based these data.

• Journal of Digital Convergence
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• v.18 no.5
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• pp.287-296
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• 2020

The purpose of this study was to investigate the effects of developing and applying taping therapy combined with heat and exercise therapy to reduce dysmenorrhea and menstrual discomfort and improve daily living ability of female college students. The study consisted of 46 female college students complaining of dysmenorrhea at K University in D city, 23 in the experimental and control groups. Questionnaires were collected and data were analyzed using SPSS statistics. The comparison of kinesi taping with heat and exercise therapy showed that taping therapy with heat and exercise therapy was more effective in reducing dysmenorrhea (t = -3.034, p = .004). The combined heat and exercise taping therapy developed in this study was found to be a more effective nursing intervention for relieving dysmenorrhea and improving daily life performance of female college students. This taping therapy is a simple method. It suggests a study to develop self-nursing education programs for girls in the community with menstrual pain and to verify the effectiveness by applying individualized education programs.

• Korean Journal of Adult Nursing
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• v.20 no.2
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• pp.269-279
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• 2008

Purpose: The study was to examine the effect of lumbar stabilization exercise on back pain, physical fitness, sleep, and depression in middle-aged women who have chronic back pain. Methods: With one group pre-post test design, 18 subjects who have had more than 6 months of back pain were recruited by convenience sampling in D metropolitan area. Lumbar stabilization exercise was based on Tai Chi for back pain program developed by Lam(2003). This program was mainly focusing on strengthening lumbar stabilizing muscle for one hour per session, twice a week for 20 weeks. Degree of back pain, back pain disability, sleep, and depression were measured at three time points(pretest, 12 weeks, and 20 weeks) by a structured study questionnaire. Physical fitness variables including waist flexibility, mobility, and back muscle strength were measured three times at health promotion center located in the university hospital. Data were analyzed by frequency, descriptive statistics, and repeated measures of ANOVA. Results: Mean age of subjects was 52 years(SD = 6.4). Most of them(90%) had suffered from back pain more than one year and 67% was taking medicine to relieve their back pain. Results showed that back pain score and disability score were not significantly decreased after the exercise. On physical fitness variables, however, waist flexibility(F = 3.50, p = .04) and mobility(F = 3.31, p = .04) were improved after the exercise. Quality of sleep(F = 4.48, p = .03) was improved gradually and depression scores were also decreased(F = 3.12, p = .05) after the exercise. Conclusion: This lumbar stabilization exercise was not able to reduce chronic back pain, but could improve physical fitness and psycho-social variables for community dwelling women who have chronic back pain. Further study is needed to replicate this exercise with control group to confirm the positive effect.

• Journal of Korean Biological Nursing Science
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• v.4 no.1
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• pp.85-99
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• 2002

This study was conducted to determine whether low intensity regular exercise following steroid treatment could attenuate steroid-induced muscle atrophy. Thirty-eight Sprague-Dawley rats weighing $165{\sim}175g$ were divided into six groups ; control group(C), dexamethasone administration group(D), sedentary normal saline administration group(C+Se), exercise after normal saline administration group(C+Ex), sedentary group after dexamethasone administration(D+Se), exercise group after dexamethasone administration(D+Ex). Either dexamethasone(5mg/kg) or normal saline was injected for 7days accordingly. Exercise was started at 10m/min on the $10^{\circ}$ grade treadmill and gradually increased up to 15m/min by the 7th day for 60minutes/day($20min{\times}3$). The data were analyzed by Kruskal-Wallis test and Mann-Whitney U test using the SPSS WIN 9.0 program. Body weight, muscle weight and myofibrillar protein content of both plantaris and gastrocnemius, Type I, II muscle fiber cross-sectional area of plantaris, and Type II muscle fiber cross-sectional area of gastrocnemius in D group were significantly lower than those of C group(p<0.05) respectively. Hindlimb muscle weight, myofibrillar protein content of both plantaris and gastrocnemius. Type I muscle fiber cross-sectional area of soleus and Type I, II muscle fiber cross-sectional area of plantaris in D+Ex group tended to increase compared to those of D+Se group. Myofibrillar protein content of both plantaris and gastrocnemius, Type I muscle fiber cross-sectional area of plantaris in D+Ex group tended to increase compared to those of C+Se group. Based on these results, it is suggested that regular low-intensity exercise during recovery period after steroid treatment might facilitate the recovery from steroid-induced muscle atrophy.