• Title/Summary/Keyword: 3-D analysis

Search Result 16,724, Processing Time 0.047 seconds

IMGT Unique Numbering for Standardized Contact Analysis of Immunoglobulin/antigen and T cell receptor/peptide/MHC Complexes

  • Kaas, Quentin;Chiche, Laurent;Lefrane, Marie-Paule
    • Proceedings of the Korean Society for Bioinformatics Conference
    • /
    • 2005.09a
    • /
    • pp.209-214
    • /
    • 2005
  • Immunoglobulins (IG) , T cell receptors (TR) and major histocompatibility complex (MHC) are major components of the immune system. Their experimentally determined three-dimensional (3D) structures are numerous and their retrieval and comparison is problematic. IMGT, the international ImMunoGeneTics information system$^{\circledR}$(http://imgt.cines.fr), has devised controlled vocabulary and annotation rules for the sequences and 3D structures of the IG TR and MHC. Annotated data from IMGT/3D sructure-DB, the IMGT 3D structure database, are used in this paper to compare 3D structure of the domains and receptor, and to characterize IG/antigen, peptide/MHC and TR/peptide/MHC interfaces. The analysis includes angle measures to assess receptor flexibility, structural superimposition and contact analysis. Up-to-date data and analysis results are available at the IMGT Web site, http://imgt.cines.fr.

  • PDF

3D-PTV Measurements of the Statistical Turbulent Properties on the Wake of a Sphere (3D-PTV에 의한 구 후류 난류통계량 계측)

  • Doh, D.H.;Hwang, T.G.;Cho, Y.B.;Baek, T.S.;Pyun, Y.B.
    • Proceedings of the KSME Conference
    • /
    • 2003.04a
    • /
    • pp.1748-1753
    • /
    • 2003
  • 3D-PTV measurement was conducted on the wake of a sphere. The Reynolds number is 1130 with the diameter(d=30mm). The measurement system consisted of three CCD cameras, an image grabber, an Ar-Ion laser and a host computer. An eigenvalue analysis was introduced for the analysis on the wake. Statistical turbulent properties were quantitatively clarified using the time-consecutive instantaneous three-dimensional vectors obtained by the 3D-PTV system. The spatial distributions of the sphere wake showed strong relations with spiral motions of the vortcies shedded from the surface of the sphere.

  • PDF

Design of Surface-Mounted Permanent Magnet Synchronous Motor Considering Axial Leakage Flux by using 2-Dimensional Finite Element Analysis

  • Lee, Byeong-Hwa;Park, Hyung-Il;Jung, Jae-Woo
    • Journal of Electrical Engineering and Technology
    • /
    • v.13 no.6
    • /
    • pp.2284-2291
    • /
    • 2018
  • This paper deals with optimum design of surface mounted permanent magnet synchronous motor (SPMSM) for automotive component. For a compact system structure, it was designed as a motor with a 14-pole 12-slot concentrated winding and hollow shaft. The motor is a thin type structure which stator outer diameter is relatively large compared to its axial length and is designed to have a high magnetic saturation for increasing the torque density. Since the high magnetic saturation in the stator core increases the axial leakage flux, a 3-dimensional (3-D) finite element analysis (FEA) is indispensable for torque analysis. However, optimum designs using 3-D FEA is inefficient in terms of time and cost. Therefore, equivalent 2-D FEA which is able to consider axial leakage flux is applied to the optimization to overcome the disadvantages of 3-D FEA. The structure for cost reduction is proposed and optimum design using equivalent 2-D FEA has been performed.

Comparison Analysis of Donor Liver Volumes Estimated with 3D Magnetic Resonance and 3D Computed Tomography Image Data

  • Kim, Myeong-Seong;Park, Kyeong-Seok;Cho, Jae-Hwan
    • Journal of Magnetics
    • /
    • v.19 no.3
    • /
    • pp.261-265
    • /
    • 2014
  • Three-dimensional computed tomography is an effective tool to estimate the liver volume of living donors for the live liver transplantation. When additional operation is required, magnetic resonance imaging is conducted to determine the safety of the donor. This study compared the accuracy of magnetic resonance imaging and computed tomography in estimating 3D liver volume of 23 male and 7 female donors who underwent both magnetic resonance imaging and computed tomography tests before the transplantation. The analysis was conducted to see whether the liver's estimated total volumes and the left lobe volumes obtained from 3D-magnetic resonance imaging and 3D-computed tomography were identical. Volumes of the right lobe estimated with 3D-magnetic resonance imaging and 3D-computed tomography were compared with the actual volume of the right lobe harvested in the operating room because the volume of the right lobe is an important determinant in the safety of the donor. The total volume of the liver estimated from 3D-magnetic resonance imaging and 3D-computed tomography differed (1238.1904 units and 1402.364 units respectively). The left lobe volume of the liver estimated with 3D-magnetic resonance imaging and 3D-computed tomography also differed (450.530 units and 554.490 units, respectively). The right lobe volume of the liver estimated with 3D-magnetic resonance imaging and 3D-computed tomography were 787.660 units and 847.545 units, respectively, while the actual average right lobe volume of the harvested liver was 678.636 units. 3D-computed tomography has been widely used to estimate the right lobe volume of the donors' liver. However, 3D-magnetic resonance imaging was also very effective in estimating the volume of the liver. Thus, 3D-magnetic resonance imaging is also expected to become an important tool in determining the safety of the donors before transplantation.

A Study on Based on the Possibility of Quantitative Analysis using Virtual Clothing Simulation according to Raglan Sleeve Pattern Types (가상 착의 시뮬레이션을 이용한 래글런 소매 패턴 변화에 따른 착의 시 정량적 분석 가능성 모색)

  • Lee, Ye-Jin;Lee, Byung-Cheol
    • Korean Journal of Human Ecology
    • /
    • v.21 no.2
    • /
    • pp.299-314
    • /
    • 2012
  • The purpose of this study was to explore effects of pattern alteration using a virtual clothing simulation approach in combination with 3D analysis software. Three raglan sleeves of different patterns were worn by an avatar using virtual clothing simulation with silk and cotton as the test fabrics. It was observed that the silhouette and hemline shape were affected differently based on raglan sleeve pattern and fabric type. By examining clothing pressure distribution, the cotton fabric designs and pattern shapes provided for a variety of influences on armhole and bust regions as well as the back sleeve area. For representative locations, cross section circumstance, cross section area, and volume were measured by using 3D analysis and the resulting correlation between the 2D and 3D data were investigated. Among different fabrics, there was little difference between the 2D and 3D clothing surface area. However, when using 3D analysis, clothing volume was significantly affected by different fabrics and pattern types. By simultaneously adopting the virtual simulator and 3D analysis, quantitative assessment of virtual clothing simulation was successfully conducted. In light of the results of this study, the resulting methodology is expected to be used as a comprehensive evaluation tool for virtual clothing simulation wear testing.

Validation of diesel engine gas flow one-dimensional numerical analysis using the method of characteristics (특성곡선법을 이용한 디젤엔진 가스유동 1차원 수치해석의 타당성 평가)

  • KIM, Kyong-Hyon;KONG, Kyeong-Ju
    • Journal of the Korean Society of Fisheries and Ocean Technology
    • /
    • v.56 no.3
    • /
    • pp.230-237
    • /
    • 2020
  • In order to design a diesel engine system and predict its performance, it is necessary to analyze the gas flow of the intake and exhaust system. A gas flow analysis in three-dimensional (3D) format needs a high-resolution workstation and enormous time for analysis. Therefore, the method of characteristics (MOC) was used for a gas flow analysis with a fast calculation time and a low-resolution workstation. An experiment was conducted on a single cylinder diesel engine to measure pressure in cylinder, intake pipe and exhaust pipe. The one-dimensional (1D) gas flow was analyzed under the same conditions as the experiment. The engine speed, valve timing and compression ratio were the same conditions and the intake pressure was inputted as the experimental results. Bent pipe such as an exhaust port that cannot be realized in 1D was omitted. As results of validation, the cylinder pressure showed accuracy, but the exhaust pipe pressure exhibited inaccuracy. This is considered as an error caused by the failure to implement a bent pipe such as an exhaust port. When analyzed in 3D, calculation time required 61 hours more based on a model of this study. In the future, we intend to implement a bent pipe that cannot be realized in 1D using 3D and prepare a method to supplement reliability by using 1D-3D coupling.

Performance Analysis of Compression Techniques Using DCT and DWT on Elemental Images in 3D Integral Imaging (3 차원 집적영상에서의 요소영상 압축을 위한 DCT 및 DWT 성능분석)

  • Muniraj, Inbarasan;Moon, In-Kyu
    • Proceedings of the Korea Multimedia Society Conference
    • /
    • 2012.05a
    • /
    • pp.340-342
    • /
    • 2012
  • Integral Imaging (II) is an attractive technique for three-dimensional (3D) image, video display and recording. Inherently, the high resolution II requires an enormous amount of data for storing and transmitting of 3D scenes. Compression techniques attempt to evade this issue. In this study, we made a comparative performance analysis of popular transforming/compression techniques such as the Discrete Cosine Transform (DCT) and the Discrete Wavelet Transform (DWT) in order to compress 3D-II. The standard baseline JPEG (Joint Photographic Experts Group) using DCT and JPEG 2000 using DWT methods were manipulated in our experiments. In our analysis, we have shown that the DWT based JPEG 2000 compression methodology could be a good alternative for 3D-II.

  • PDF

Development of Automated J-Integral Analysis System for 3D Cracks (3차원 J적분 계산을 위한 자동 해석 시스템 개발)

  • 이준성
    • Journal of the Korean Society for Precision Engineering
    • /
    • v.17 no.7
    • /
    • pp.74-79
    • /
    • 2000
  • Integrating a 3D solid modeler with a general purpose FEM code, an automatic nonlinear analysis system of the 3D crack problems has been developed. A geometry model, i.e. a solid containing one or several 3D cracks is defined. Several distributions of local node density are chosen, and then automatically superposed on one another over the geometry model by using the fuzzy knowledge processing. Nodes are generated by the bucketing method, and ten-noded quadratic tetrahedral solid elements are generated by the Delaunay triangulation techniques. The complete finite element(FE) model generated, and a stress analysis is performed. In this system, burden to analysts fur introducing 3D cracks to the FE model as well as fur estimating their fracture mechanics parameters can be dramatically reduced. This paper describes the methodologies to realize such functions, and demonstrates the validity of the present system.

  • PDF

MALDI-MS-Based Quantitative Analysis of Bioactive Forms of Vitamin D in Biological Samples

  • Ahn, Da-Hee;Kim, Hee-jin;Kim, Seong-Min;Jo, Sung-Hyun;Jeong, Jae-Hyun;Kim, Yun-Gon
    • Korean Chemical Engineering Research
    • /
    • v.58 no.1
    • /
    • pp.106-112
    • /
    • 2020
  • Analyzing vitamin D levels is important for monitoring health conditions because vitamin D deficiency is associated with various diseases such as rickets, osteomalacia, cardiovascular disorders and some cancers. However, vitamin D concentration in the blood is very low with optimal level of 75 nmol/L, making quantitative analysis difficult. The objective of this study was to develop a highly sensitive analysis method for vitamin D using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-MS). 25-hydroxyvitamin D (25(OH)D), which has been used as an indicator of vitamin D metabolites in human biofluids was chemically derivatized using a secosteroid signal enhancing tag (SecoSET) with powerful dienophile and permanent positive charge. The SecoSET-derivatized 25(OH)D provided good linearity (R2 > 0.99) and sensitivity (limit of quantitation: 11.3 fmol). Chemical derivatization of deuterated 25-hydroxyvitamin D3 (d6-25(OH)D3) with SecoSET enabled absolute quantitative analysis using MALDI-MS. The highly sensitive method could be successfully applied into monitoring of quantitative changes of bioactive vitamin D metabolites after treatment with ketoconazole to inhibit 1α-hydroxylase reaction related to vitamin D metabolism in human breast cancer cells. Taken together, we developed a MALDI-MS-based platform that could quantitatively analyze vitamin D metabolites from cell products, blood and other biofluids. This platform may be applied to monitor various diseases associated with vitamin D deficiency such as rickets, osteomalacia and breast cancer.