• Asian Pacific Journal of Cancer Prevention
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• v.13 no.3
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• pp.827-831
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• 2012

To determine the relationship between comorbidity and outcome after radical cystectomy in Chinese patients by using the Adult Comorbidity Evaluation (ACE)-27 index. Two-hundred-and-forty-six patients treated with radical cystectomy at the Second Xiangya Hospital of Central South University, Hunan Province, China between 2000 and 2010 were retrospectively analyzed. Medical records were reviewed for age, gender, delayed time of radical cystectomy, urinary diversion type, pelvic lymphadenectomy status, TNM stage, and pathological grade. Comorbidity information was assessed by the ACE-27 index. The outcome measurement was overall survival. Univariate and multivariate Cox proportional hazards regression analyses were used to determine the association between comorbidity and outcome. The study population consisted of 215 (87.40%) males and 31 (12.60%) females with a mean age of $62{\pm}11$ years. Median duration of follow-up was $47{\pm}31$ months. A total of 151 (61.38%) patents died during follow-up. Of those, 118 (47.97%) had at least one comorbidity. According to the ACE-27 scores, 128 (52.03%) patients had no comorbidity, 79 (32.11%) had mild, 33 (13.41%) had moderate, and 6 (2.45%) had severe comorbidities. Multivariate analysis indicated that moderate (p=0.002) and severe (p<0.001) comorbidity was significantly associated with decreased overall survival. In addition, age ${\geq}70$ years (p=0.002), delayed time of radical cystectomy >12 weeks (p=0.044), pelvic lymphadenectomy status (p=0.014), and TNM stage >T3 (p<0.001) were determined to be independent risk factors of overall survival. Increasing severity of comorbidity statistically correlated with decreased overall survival after radical cystectomy.

• The Journal of Korean Academic Society of Nursing Education
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• v.6 no.2
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• pp.199-217
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• 2000

This descriptive longitudinal study was done to identify the ethical value of nursing students and to compare the differences of results with one year interval. The data were collected twice in 1999 and in 2000, from the 82 first year and 64 second year nursing students who have been attending at C college in Chonnam province. The analysis of data was done by frequency, mean, paired t-test, t-test, and ANOVA. The results of data were summarized as follows: 1. The total ethical value score of the first year students was 3.48 (maximum : 5) and, one year later, the score was lowered to 3.26. Especially, the degree of their ethical value was significantly decreased in the sub-areas of human-life and nurse-nursing task. 2. The total ethical value score of the second year students was 3.24 and, one year later, the score was increased to 3.39. The degree of their ethical value was significantly increased in the subarea of nurse- client relationship. 3. In the subarea of human-life, the mean score of ethical value was 3.25 and, one year later, the score was 2.95. The degree of ethical value was significantly lowered among the first year students with an utilitarian position. 4. In the subarea of nurse-client relationship, the mean score of ethical value was 3.39 and, one year later, the score was 3.67. The degree of ethical value was significantly increased among the second year students with a deontological position. 5. In the subarea of nurse-nursing task relationship, the mean score of ethical value was 3.38 and, one year later, the mean score was 3.08. The degree of ethical value was significantly decreased among the first year students. 6. In the subarea of nurse-collaboration relationship, the mean score of ethical value was 3.96 and, one year later, the mean score was 4.08 in second year students. There was no statistically significant difference. 7. The ethical values of nursing students were significantly different depending on their religion, length of study, attitude toward nursing and the experience of dying during their clinical practice.

• Journal of Ginseng Research
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• v.46 no.6
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• pp.771-779
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• 2022

Background: As a kind of common complication of the surgery of perianal diseases, perianal ulcer is known as a nuisance. This study aims to develop a kind of 20(S)-ginsenoside Rg3 (Rg3)-loaded hydrogel to treat perianal ulcers in a rat model. Methods: The copolymers PLGA₁₆₀₀-PEG₁₀₀₀-PLGA₁₆₀₀ were synthesized by ring-opening polymerization process and Rg3-loaded hydrogel was then developed. The perianal ulcer rat model was established to analyze the treatment efficacy of Rg3-loaded hydrogel for ulceration healing for 15 days. The animals were divided into control group, hydrogel group, free Rg3 group, Rg3-loaded hydrogel group, and Lidocaine Gel® group. The residual wound area rate was calculated and the blood concentrations of interleukin-1 (IL-1), interleukin-6 (IL-6), and vascular endothelial growth factor (VEGF) were recorded. Hematoxylin and eosin (H&E) staining, Masson's Trichrome (MT) staining, and tumor necrosis factor α (TNF-α), Ki-67, CD31, ERK1/2, and NF-κB immunohistochemical staining were performed. Results: The biodegradable and biocompatible hydrogel carries a homogenous interactive porous structure with 10 ㎛ pore size and five weeks in vivo degradation time. The loaded Rg3 can be released sustainably. The in vitro cytotoxicity study showed that the hydrogel had no effect on survival rate of murine skin fibroblasts L929. The Rg3-loaded hydrogel can facilitate perianal ulcer healing by inhibiting local and systematic inflammatory responses, swelling the proliferation of nuclear cells, collagen deposition, and vascularization, and activating ERK signal pathway. Conclusion: The Rg3-loaded hydrogel shows the best treatment efficacy of perianal ulcer and may be a candidate for perianal ulcer treatment.

• Communications of the Korean Mathematical Society
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• v.34 no.1
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• pp.303-319
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• 2019

The aim of the present paper is to study the Eisenhart problems of finding the properties of second order parallel tensors (symmetric and skew-symmetric) on a 3-dimensional LCS-manifold. We also investigate the properties of Ricci solitons, Ricci semisymmetric, locally ${\phi}$-symmetric, ${\eta}$-parallel Ricci tensor and a non-null concircular vector field on $(LCS)_3$-manifolds.

• Journal of Periodontal and Implant Science
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• v.31 no.3
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• pp.573-579
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• 2001

The purpose of this study was to investigate the characteristiss of korean multi-rooted teeth extracted by periodontal disease. A total of 182 extracted multi-rooted teeth were examined. The distance from the cementoenamel junction(CEJ) to the root groove and from the CEJ to the root division was measured. The frequency of the root grooves were calculated. The results are as follows : 1. Distances from CEJ to the root groove were $1.53{\cdot}1.60mm$ for maxillary first premolars mesial${\cdot}$distal sides, $1.26{\cdot}1.38{\cdot}1.75mm$ for maxillary first molars buccal${\cdot}$mesial${\cdot}$distal sides, $1.38{\cdot}1.71{\cdot}1.41mm$ for maxillary second molars buccal${\cdot}$mesial${\cdot}$distal sides, $0.98{\cdot}0.99mm$ for mandibular first molars buccal${\cdot}$lingual sides and $1.28{\cdot}1.35mm$ for mandibular second molars buccal${\cdot}$lingual sides. 2. The frequency of the root grooves were $17.4{\cdot}30.4%$ for maxillary first premolars mesial${\cdot}$distal sides, $44.4{\cdot}84.1{\cdot}67.5%$ for maxillary first molars buccal${\cdot}$mesial${\cdot}$distal sides, $100{\cdot}90.3{\cdot}90.3%$ for maxillary second molars buccal${\cdot}$mesial${\cdot}$distal sides, $42.9{\cdot}77.8%$ for mandibular first molars buccal${\cdot}$lingual sides and 90.6% for mandibular second molars buccal${\cdot}$lingual sides. 3. Distances from CEJ to the root division were $6.8{\cdot}7.2mm$ for maxillary first premolars mesial${\cdot}$distal sides, $3.3{\cdot}4.38{\cdot}4.34mm$ for maxillary first molars buccal${\cdot}$mesial${\cdot}$distal sides, $3.67{\cdot}4.8{\cdot}4.07mm$ for maxillary second molars buccal${\cdot}$mesial${\cdot}$distal sides, $3.1{\cdot}3.89mm$ for mandibular first molars buccal${\cdot}$lingual sides and $3.2{\cdot}4.06mm$ for mandibular second molars buccal${\cdot}$lingual sides.

• Journal of Korean Society of Environmental Engineers
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• v.22 no.7
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• pp.1243-1252
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• 2000

The differential enhanced degradation of cis- and trans-1,3-D was observed in the previous two studies performed by several researchers. This study was initiated to investigate the involvement of microorganisms in the differential enhanced degradation of the chemicals. As expected, microorganisms were responsible for the enhanced degradation. A mixed bacterial culture capable of degrading 1,3-D was isolated from an enhanced soil sample collected from a site treated with 1,3-D. Similar to the enhanced soil, the mixed culture degraded trans-1,3-D faster than cis-1,3-D. This mixed culture could not utilize cis- and trans-1,3-D as a sole source of carbon for growth. Rather, a variety of second substrates were evaluated to stimulate the differential enhanced degradation of the two isomers. As a result, the mixed culture degraded cis- and trans-1,3-D only in the presence of a suitable second substrate. Therefore, it appeared that the degradation of cis- and trans-1,3-D was a cometabolic process. Second substrates that had the capacity to stimulate the degradation included soil leachate, tryptone, tryptophan, and alanine. Other substrates tested. including soil extract. glucose, yeast extract and indole, failed to stimulate the degradation of the two isomers. The mixed culture was composed of four morphologically distinctive colonies on L-agar plates.

• Current Optics and Photonics
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• v.5 no.4
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• pp.458-465
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• 2021

Borate nonlinear optical crystals have been used as frequency conversion devices in many fields due to their unique transparency and nonlinearity from ultraviolet to visible spectral range. In this study, we theoretically and numerically investigate the properties of broadband second harmonic generation (SHG) in the recently reported Pna2₁-Ba₃Mg₃(BO₃)₃F₃ (BMBF) crystal. The technique is based on the simultaneous achievement of birefringence phase matching and group velocity matching between interacting waves. We discussed all factors required for broadband SHG in the BMBF in terms of two types of phase matching and group velocity matching conditions, the beam propagation direction and the corresponding effective nonlinearity and spatial walk-off, and the spectral responses. The results show that bandwidths calculated in the broadband SHG scheme are 220.90 nm (for Type I) and 165.85 nm (for Type II) in full-width-half-maximum (FWHM). The central wavelength in each case is 2047.76 nm for Type I and 1828.66 nm for Type II at room temperature. The results were compared with the non-broadband scheme at the telecom C-band.

• Journal of Veterinary Clinics
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• v.15 no.2
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• pp.427-431
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• 1998

This study was undertaken to investigate the effect of exercise induced pulmonary hemorrhage(EIPH) on the finishing position of racehorses, 400 bleeders(305: 1 time, 76: 2 times, 19: 3 times, total: 514 cases) which had bled(EIPH) from their nostrils after their races at the Seoul racecourse during the 5 years period('93-'97) were analyzed for this study. The ratio of bleeders to total racehorses in finishing position 1-3,4-6, 7-9 or above 10 was 0.55, 0.84, 0.90 or 1.13%, respectively. There is tendency to higher incidence of bleeding in the later positioned racehorses group. To analyze the correlation between EIPH and finishing position, finishing potion of each EIPHed horses' was checked at 7 successive races(3 races each before/after EIPH. The average final position at the -3rd race, -2nd racer -lst racer EIPHed race, 1st race,2nd race and 3rd race of each bleeder was 5.85. 5.94, 6.21, 7.32, 7.20, 6.51 and 6.53, respectively. Raring times were adjusted to 1,000 m equivalent. Average racing times of the -3rd race,-2nd racer -lst raced EIPHed race, 1st race, 2nd race and 3rd race of each bleeder was 67.1, 67.1, 67.2, 67.6, 67.5, 67.4 and 67.3 second, respectively. Bleeders which finished the race within 1 second following the winners were 25. 3% of total bleeders. The rest 74.7% reached at the finish line 1 second later than the winners. Particularly 46.3% of bleeders were above 2 second later. Therefore this study suggested that bleeding has effect on performance of the racehorse, consequently it make bleeders be placed later positions.

• Fashion & Textile Research Journal
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• v.22 no.1
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• pp.11-24
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• 2020

This research examines pattern production of 3 men's costumes in the second half of 19th century by 3D reconstruction to reveal technical aspects of mail costumes. The steps are as follows. First, an examination of selective type according to research study. Second, a pattern analysis of 3 historical male tops of 19th century referred to 9 pattern books of the France National Library collection. Third, a categorized type analysis that referred to paintings of the Musée d'Orsay collection. Fourth, a measurement and structure research of 3 historical garments of Fashion and Textile Museum collection. Fifth, the pattern making and fitting by 3D simulation. Research discussed the following subjects and results. First, main type of men's coat can be categorized by frac, redingote, jaquette, and veston. Second, the male costume pattern contained in pattern books was researched along with distinguished silhouettes and structures; X silhouette for frac and redingote, H silhouette for jaquette, and straight box silhouette for veston. Third, based on the analysis of representative type of men's costume per period conducted previous studies, 2 redingotes and a jaquette in the museum were selected and compared to other data such as image materials. Last, the following process was conducted for reconstruction; 'Drawing diagram-Primary pattern drafting by measurement value-3D virtual fitting-Checking the fit-Modification and complement'. We also obtained a 3D virtual reconstruction and a 2D research pattern that suggested a costume pattern by each type along with 3D reconstruction that included insights for male coat techniques of 19th century France.

• Journal of Korean Foot and Ankle Society
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• v.10 no.2
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• pp.133-139
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• 2006

Purpose: To evaluate the results of mosaicplasty and microfracture after surgical treatments for symptomatic osteochondral lesion of talus (OLT) by second-look arthroscopy. Materials and Methods: 7 cases of mosaicplasty and 7 cases of microfracture were reviewed who undertook second-look arthroscopy at 6 months or one year after undertaking mosaicplasty or microfracture for OLT between December 2004 and October 2005. The mean age at first operation was 43.6 years (Range, 20-59) (Mosaicplasty; 43.9 years, Microfracture; 43.4 years). The mean size of cartilage defect was $15.0{\times}7.7\;mm$ in mosaicplasty and $7.1{\times}6.6\;mm$ in microfracture. Clinical outcomes were evaluated by Freiburg ankle score. Cartilage healing state was evaluated by Insall's classification for chondromalasia during second-look arthroscopy. Results: By the Freiburg ankle score, 9 ankles (6 in mosaicplasty, 3 in microfracture) had excellent and 5 (1 in mosaicplasty, 4 in microfracture) had good results at the times of second-look arthroscopy. By Insall's classification, consistency of the osteochondral grafts and congruity between grafts and native cartilage (Grade I) were shown in 9 (6 ankles in mosaicplasty, 3 ankles in microfracture), a fissuring (Grade II) in one ankle of mosaicplasty, a fasciculation (Grade III) in one ankle of microfracture, and partial exposure of subchondral bone (Grade IV) in 3 ankles of microfractures. Conclusion: Mosaicplasty was more excellent in consistency and hardness of cartilage than microfracture. In some cases of microfracture, cartilage healing was incomplete at 6 months postoperatively, so second-look arthroscopy is necessary to identify. If incomplete cartilage healing was shown, additional procedure such as microfracture or mosaicplasty was needed.