• Korean Journal of Medicinal Crop Science
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• v.11 no.2
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• pp.122-126
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• 2003

This study was conducted to investigate plant growth characteristics and anatomical studies of Korean mistel (Viscum album var. coloratum (Kom.) Ohwi). Parasite position was upper part that has a plenty of sunshine area 5 to 10m apart from the ground, regardless host tree. Stem developed two branch stems from the each basal stem, leaf was grown from the end stems as opposite. Fruit has a light yellow color and berry size was 7 to 8 mm long diameter and it contains seed. Floral bud differentiation initiated with forming rounded dome and arch-shaped floral apex at the beginning stage, and produced heart-shaped sepal following the differentiation of leaf primordia. Floral bud formation processed centeral part first and following bilateral sides were developed in order. Leaf was thick and stoma and guard cell were observed from the two or three inner layers from the epidermis. Mistletoe penetrated cork cambium of host plant and was growing by rooting on xylem. Korean mistel connected to host plant through parasitic organ, haustorium structurally and physiologically.

• KSBB Journal
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• v.17 no.6
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• pp.566-570
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• 2002

In lactic acid fermentation, the end product inhibition by lactic acid causes several problems. The most important of which are low lactate formation rate and its recovery from fermentation broth. To overcome these problems, extractive lactic acid fermentation was carried out in a bioreactor, which was connected to a column packed with anion exchange resin (Amberlite IRA-400, 250 g). The system was started as a batch process, and then the separation process was started when the lactic acid concentration reached 10 g/L, 20 g/L or 30 g/L. In each case, total lactic acid concentration was reached to 48.6, 53.6, 52.6 g/L with its productivity of 1.2 g/L $.$ h, 1.6 g/L $.$ h, and 1.3 g/L $.$ h, respectively Especially, in the case of the 20 g/L recycling-initiation process, extractive fermentation reduced tie fermentation time (17 hrs) by 34% in comparison with the conventional batch process. The direct consequence of this time reduction was shown by a 1.8 fold increase in overall lactic acid productivity.

• Journal of Sasang Constitutional Medicine
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• v.10 no.1
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• pp.311-341
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• 1998

The objective of this article is to induce that the conception of 'Qi-jul(氣質) and Qi-pum(氣稟)' was introduced to the Sasang(四象) Constitutional Medicine from bibliographic study on the theory of 'Qi-pum(氣稟)'. The conclusions summerized as followings. 1. In the oriental medicine, qualitative difference of 'zheng-qi(正氣)' among the individuals, the opposing power against a disease, is regarded as constitution. Having been used as 'nature(素)', 'quality(質)' and 'character(氣質)' in the oriental medical book, the word of 'Che-Jil(體質)' was used in good earnest at the end of 'Qing(情)' dynasty. 2. The nature(性) is divided into two, original nature(本然之性) and charicteristic nature(氣質之性) in the 'New confucianism(新儒學)' and the former means a principle(理), is a pure and good thing and used as a conception of universality, the latter is a principle of character and a imperfect imitation of principle(理). 3. It was repeatedly confirmed that 'Qi-jil and Qi-pum' meant the difference among the individuals by the dispute of 'Li-Qi(理氣)' caused by Lee Hwang(李滉) and Lee Yi(李耳) and by that of 'Ho-Rak(湖洛)' in the Ch'o-son(朝鮮) dynasty. 4. Han Sok-Ji, based on Meng-Zi(孟子)'s doctrine that man's inborn nature is good, criticized the theory of 'Qi-pum' which was 'Zhu-Zi(朱子)'s opinion and his opinion about the life(命) was thought to clue to the classification of the 'Sasang(四象)' invented by Lee Je-Ma as Park Se-Dang's theory that everyone has common nature but has different life(命). 5. By introducing the theory of 'Qi-pum' and the conception of life(命) which was understood as a special character by Han Sok-Ji and Park Se-Dang to Sa-sang constitutional medicine, Lee Je-Ma explained the reason why each man who was classified four constitutions, 'Taiyang'(太陽), 'Taiyin'(太陰), 'Shaoyang'(少陽), 'Shaoyin'(少陰), had the different formation of the visceral department(臟局).

• Journal of Ginseng Research
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• v.44 no.4
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• pp.593-602
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• 2020

Background: Heat stress orchestrates neurodegenerative disorders and results in the formation of reactive oxygen species that leads to cell death. Although the immunomodulatory effects of ginseng are well studied, the mechanism by which ginseng alleviates heat stress in the brain remains elusive. Methods: Rats were exposed to intermittent heat stress for 6 months, and brain samples were examined to elucidate survival and antiinflammatory effect after Korean Red Ginseng (KRG) treatment. Results: Intermittent long-term heat stress (ILTHS) upregulated the expression of cyclooxygenase 2 and inducible nitric oxide synthase, increasing infiltration of inflammatory cells (hematoxylin and eosin staining) and the level of proinflammatory cytokines [tumor necrosis factor α, interferon gamma (IFN-γ), interleukin (IL)-1β, IL-6], leading to cell death (terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling assay) and elevated markers of oxidative stress damage (myeloperoxidase and malondialdehyde), resulting in the downregulation of antiapoptotic markers (Bcl-2 and Bcl-x_L) and expression of estrogen receptor beta and brain-derived neurotrophic factor, key factors in regulating neuronal cell survival. In contrast, KRG mitigated ILTHS-induced release of proinflammatory mediators, upregulated the mRNA level of the antiinflammatory cytokine IL-10, and increased myeloperoxidase and malondialdehyde levels. In addition, KRG significantly decreased the expression of the proapoptotic marker (Bax), did not affect caspase-3 expression, but increased the expression of antiapoptotic markers (Bcl-2 and Bcl-x_L). Furthermore, KRG significantly activated the expression of both estrogen receptor beta and brain-derived neurotrophic factor. Conclusion: ILTHS induced oxidative stress responses and inflammatory molecules, which can lead to impaired neurogenesis and ultimately neuronal death, whereas, KRG, being the antioxidant, inhibited neuronal damage and increased cell viability.

• Clean Technology
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• v.23 no.2
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• pp.148-157
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• 2017

To prepare UV-curable polyurethane-acrylate oligomer, NCO-terminated urethane prepolymers with trimethylolpropane, [TMP; 0 (0), 0.1 (0.021) and 0.2 (0.043) mole (mole fraction)] as crosslinkable tri-functional chain extender were end-capped with pentaerythritol triacrylate [PETA; 2.0 (0.400), 1.7 (0.354) and 1.4 (0.304) mole (mole fraction)] with one hydroxyl group/three vinyl functionalities. The stable as-formulated UV-curable polyurethane-acrylates [stable mixtures of PETA-capped oligomer/reactive acrylic monomer diluents without/with heptadecafluorodecyl methacrylate (PFA; 0, 6 and 9 wt%)] were formed up to 0.2 (0.043) mole (mole fraction) of TMP content in the prepolymer, while homogeneous-mixing failed at 0.3 (0.068) mole (mole fraction), in which the crosslink density in NCO-terminated urethane prepolymer was too high to enable the formation of stable mixture. This study examined the effect of TMP/PETA molar ratio and heptadecafluorodecyl methacrylate (PFA) content (wt%) on the properties of UV-cured polyurethane-acrylates as marine antifouling coating materials. The properties of UV-cured polyurethane-acrylate were found to be significantly dependent on the crosslinkable TMP/PETA ratio and PFA content. With the increasing of the TMP and PFA contents, the contact angles increased, and consequently the surface tension decreased. The adhesion of algae/barnacles to PFA contained film samples were found to be sufficiently weak to allow their easy removal. These results suggest that the UV-cured samples containing PFA have strong potential as coating materials for antifouling applications.

• Journal of Korean Society of Water and Wastewater
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• v.18 no.2
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• pp.254-269
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• 2004

Polysilicato-iron coagulant (PSI) is receiving attention in Japan as a substitute for aluminum-based coagulants. In the first part of this article, coagulation, sedimentation and filtration experiments were carried out using kaolin clay particles as the turbidizing material and four types of PSI with various molar ratios of polysilicic acid to ferric chloride (Si/Fe ratio). Results demonstrate that use of a PSI with a high Si/Fe ratio can cause a more dramatic decrease in treated water turbidity but a higher suction time ratio (STR) than when PACl is used. However, optimization by increasing the rapid agitation strength GR is found to greatly improve the STR. In addition, the series of filtration experiments verified that optimization of GR is greatly effective in controlling rapid increases in filter head loss, and also formation of a thin aging layer in the upper part of the filter bed by slow-start filtration is effective in improving filtered water turbidity over the entire filtration process. The second part of this article describes two innovative filtration techniques to increase the particle separation efficiency; (1) coagulant-coated filter medium by enhancing the electrical potential of the surface of the filter medium, and (2) coagulant dosing in influent by controlling the electrical potential of particles entering the filter layer. From the results of the various filtration experiments using a pilot plant, these two techniques were found to be very effective to reduce the effluent water turbidity from the start to the end of a filter run. Moreover, in the filtration experiments using these two methods simultaneously, higher removal efficiency of approximately 3-log (99.7%) was realized, resulting that the finished water turbidity was accordingly reduced to 0.004mg/L.

• International Journal of Oral Biology
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• v.30 no.3
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• pp.99-103
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• 2005

Bone morphogenetic proteins (BMPs), members of a large group of TGF-beta family, are important molecular regulators of morphogenesis of numerous tissues and organs, including bones and teeth. Most BMPs are capable of inducing bone formation in vivo and therefore are of considerable clinical interest for regenerating mineralized tissues. Recently, we have developed a method to culture cells from human cementum (human cementum-derived cells, HCDCs). HCDCs, when attached to synthetic hydroxyapatite/tricalcium phosphate (HA/TCP) ceramic and transplanted into immunodeficient mice, formed histologically identifiable cementum-like tissue. Since it is unclear to what extent BMPs are involved in cementogenesis, the aim of this study was to establish which BMPs are expressed by cementogenic HCDCs and whether the expression of BMPs is related to the degree of cellular differentiation in vitro. HCDCs were maintained in growth medium (DMEM/F12 supplemented with 10% FBS) until confluent (proliferation stage). Upon reaching confluence, cells were incubated in the differentiation medium (DMEM/F12 medium containing 10% FBS and 50 mg/ml ascorbic acid) for 14 days (differentiation stage). Next, HCDCs were incubated in mineralization medium (DMEM/F12, 50 mg/ml ascorbic acid, 2.5 mg/ml of ITS (insulin-transferrinselenium), 5 mM beta-glycerophosphate and $10^{-8}M$ dexamethasone) for another 14 days (mineralization stage). At the end of each differentiation stage, total RNA was isolated and evaluated for BMPs (2 through 8) expression by employing real time RT-PCR. HCDCs expressed most of BMPs examined except BMP-7 and BMP-8. Furthermore, on average, the highest levels of BMPs were expressed at the earlier differentiation stage, prior to the initiation of mineralization in vitro. These results indicate that several BMPs are expressed during cementoblastic differentiation and suggest that BMPs may be involved in the homeostasis of human cementum.

• The Journal of Korean Academy of Prosthodontics
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• v.16 no.1
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• pp.7-11
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• 1978

The author attempted to observe the histological changes of the periodontal structures induced by trauma from occlusion. Eighteen healthy rabbits were devided into two groups; control and experimental group. Three rabbits were kept as control group, while metal crowns were seated on unilateral lower molar teeth of fifteen rabbits were kept as experimental group. And the interocc1usal distance of the incisal edge was kept 1.5mm from begining to the end of the experimental period. Rabbits of each group consisting with three rabbits were killed at the intervals of three days, one week, two weeks, four weeks, eight weeks. The antagonistic teeth of maxilla including periodontal teeth were excised and decalcified for histologic preparation. The results obtained were as follows. 1. Destructions and ulcer formation of the sulcular epithelium and gingival epithelium occurred and persisted from the beginning of the experiment to the four weeks after experiment. The epithelal attachment were proliferated apically. 2. The pressure site were observed at the apical protion, where they showed compression of the periodontal ligament, thrombosis and congestion of blood vessels and hemorrhages. 3. At the pressure site, there appeared osteoclasts and bone resorption from the first week of experiment and it became more prominent at the second week with the extend into the marrow spaces adjacent to the periodontal membrane. 4. The phenomenon of bone apposition and resorption occurred at the fourth week of experiment. The reverse line of bone trabecular were more prominent. And the reactions were ceased at the eighth week of experiment.

• Journal of the Korean Institute of Educational Facilities
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• v.5 no.1
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• pp.33-43
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• 1998

With increased social participation of married women and with the notion of importance of pre-school childhood on human development, the importance of nurseries is being emphasized. The transformation of the traditional family system into a nuclear family system and the deterioration of the traditional child education have also put nurseries as a primal social interest. But, at present, at the end of 1994, only 10% of the children have benefitted from such facilities, the supply not being able to meet demand. Also, the spatial organization and the management of such facilities has been unsatisfactory. In this perspective, this study aims to grasp the present condition of nurseries, to investigate and analyse case studies, to suggest standards and reform measures, and based on these, to produce basic information for the formation of an architectural spatial model. We've selected investigation of present conditions and case studies, interviews, and observation as investigative methods and through these we've assessed tangible spatial planning and spatial proportion by parts. 1. The most preferred grouping method is toddler/preschooler type, and the group size and staff-to-child ratios vary according to the children's age 2. The younger children's activity rooms are located in the lower level, and the activity room of the children on the similar development stages are located adjacent to one another 3. Most of the facilities do not have the public spaces(indoor playrooms, dinning rooms, napping rooms, bathrooms, sickrooms) For dinning and napping, activity rooms are being used, and for sickrooms, director's room or staff rooms 4. As for the correlations of the spaces(home bases, activity rooms and its outdoor spaces, day-care-centers and its community), closed plan type is 90% over, and modified open plan is 10% min.

• Journal of Chest Surgery
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• v.48 no.1
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• pp.46-51
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• 2015

Background: Maintenance of adequate vascular access for hemodialysis is important in patients with end-stage renal disease. Once arteriovenous fistula (AVF) occlusion occurs, the patient should be treated with rescue therapy. This study was performed to evaluate the results of a rescue therapy for AVF occlusion. Methods: From January 2008 to December 2012, 47 patients who underwent surgical rescue therapy for AVF occlusion after graft AVF formation, were enrolled in this study. The patients were divided into two groups, namely the graft repair group (group A, n=19) and the thrombectomy group (group B, n=28). Postoperative results of both groups were analyzed retrospectively. Results: There were no statistically significant differences in the clinical characteristics between the two groups. In terms of the duration of AVF patency after the first rescue therapy, group A showed a longer AVF patency duration than group B ($24.5{\pm}21.9$ months versus $17.7{\pm}13.6$ months), but there was no statistically significant difference (p=0.310). In terms of the annual frequency of AVF occlusion after the rescue therapy of group A was lower than that of group B (0.59 versus 0.71), but there was no statistically significant difference (p=0.540). The AVF patency rates at 1, 2, 3, and 5 years after the first rescue therapy in group A were 52.6%, 31.5%, 21.0%, and 15.7%, respectively, and those in group B, they were 32.1%, 25.0%, 17.8%, and 7.14%, respectively. There was no statistically significant difference (p=0.402). Conclusion: Graft repair revealed comparable results. Although there was no statistically significant difference, the patent duration and annual frequency of AVF occlusion of group A were better than those of group B. Therefore, graft repair is considered as a safe and useful procedure for maintaining graft AVF.