• Asian-Australasian Journal of Animal Sciences
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• v.9 no.1
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• pp.37-44
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• 1996

The present study was conducted to investigate the role of thyroid hormones in the regulation of gene expression of calbindin-$D_{28k}$ (CaBP-D28K) in the chicken. By employing slot blot and RIA analyses, levels of CABP-D28K mRNA and CaBP-D28K protein in the intestine, kidney, cerebellum and liver were measured 6 and 12 h after i.m. injection of 1, 25-dihydroxyvitamin $D_3$ [1, 25 $(OH)_2D_3$; 250 ng/chick] and 3, 5, 3'-triiodothyronine ($T_3$; 500 ng/chick) in one-day-old chicks. The abundant messages of CaBP-D28K mRNA were detected in the intestine, kidney and cerebellum while there was little message in the liver. After 1, 25 $(OH)_2D_3$ treatment (6 + 12 hours), levels of CaBP-D28K mRNA increased in the intestine, but there was no change in the mRNA levels in the kidney and cerebellum. Although $T_3$ alone had no effect on CaBP-D28K mRNA levels, simultaneous administration of $T_3$ enhanced the 1, 25 $(OH)_2D_3$ effect of levels of CaBP-D28K mRNA in the intestine both 6 and 12 h post-treatment, and in the kidney 12 h post-treatment. At a protein level, co-treatment with 1, 25 $(OH)_2D_3$ and $T_3$ elicited a significant increase in CaBP-D28K expression in the intestine 12 h post-treatment, as compared to treatment with only 1, 25 $(OH)_2D_3$, whereas no differences were observed in the CaBP-D28K protein levels in the kidney and cerebellum. These results suggest that thyroid hormones may play a synergistic role with 1, 25 $(OH)_2D_3$ for CaBP-D28K gene expression in the intestine and kidney in chicks.

• Journal of Digital Contents Society
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• v.11 no.4
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• pp.425-431
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• 2010

This study explored the effects and the effectiveness of the new method of 3D FIESTA by making quantitative comparison with the conventional 3D FSE method which is frequently employed on patients with sudden hearing loss in clinical settings. For this study, 3D FSE images acquired with 3.0T MR scanner and T2-weighted axial plane 3D FIESTA images were respectively taken from 40 patients diagnosed with Sensorineural Hearing Loss (SSHL). When obtaining those images, sagittal reconstructions oriented perpendicular to the nerve were performed in order to get sagittal images of both right and left internal auditory canal. The findings showed that both SNR and CNR were higher among the group to whom the 3D FIESTA method was applied than the group to whom the conventional 3D FSE method was applied.

• Journal of Life Science
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• v.24 no.7
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• pp.798-803
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• 2014

Cathepsin D (CtsD), an aspartyl peptidase, is involved in apoptosis, resulting in the release of cytochrome C from mitochondria in cells. Here, we investigated microRNA regulation of CtsD expression in 3T3-L1 cells First, we observed the expression of CtsD in cells in response to doxorubicin (Dox). As expected, the level of CtsD mRNA was increased in 3T3-L1 cells exposed to Dox in a dose-dependent manner. Cellular viability of ectopically expressed CtsD cells was also decreased. Next, we used the miRanda program to search for particular microRNA targeting CtsD. MiR-145 was selected as a putative controller for CtsD because miR-145 had a high mirSVR score. In a reporter assay, the luciferase activity of cells containing the CtsD 3'-UTR region was decreased in cells transfected with miR-145 mimic compared to that of a control. The level of CtsD expression was down-regulated in preadipocytes ectopically expressing miR-145 and up-regulated by an miR-145 inhibitor. Cells also suppressed miR-145 expression when exposed to Dox. The miR-145 inhibitor reduced the cellular viability of 3T3-L1 cells. Taken together, these data suggest that miR-145 regulates CtsD-mediated cell death in adipocytes. These findings may have valuable implications concerning the molecular mechanism of CtsD-mediated cell death in obesity, suggesting that CtaD could be a useful therapeutic tool for the prevention and treatment of obesity by regulating fat cell numbers.

• The Journal of the Korea institute of electronic communication sciences
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• v.15 no.2
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• pp.225-230
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• 2020

The development of the industrial revolution can confirm the paradigm of manufacturing is changing from the mass production of small varieties to the form of small-scale production of many varieties. That is a form that can reduce the burden of indiscriminate raising of producers and a change in the industrial form that seeks to make up for the problems of the productivity portion that should change as modern society develops. Looking at the 3D printing environment, there are many problems in reaching the final stage of printing. The problem is not just the low-cost, low-end 3D Pirnter, but the high-priced 3D Printers released as finished products also show the same symptoms. This can cause anxiety factors in the printing process. Therefore, the research was conducted to compensate such problems. Based on the research, we propose the design of IoT beacon-based 3D Printer remote safety and quality control system targeting 3D Printer individual users.

• 한국정보디스플레이학회:학술대회논문집
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• 2006.08a
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• pp.1311-1313
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• 2006

Stereoscopic/autostereoscopic systems have been developed in order to express true 3D images, but have never had great success in the practical use. In order to apply 3D display to promising applications such as advertisements and games, we've developed a 42" 2D/3D switchable display. It has characteristics that don't require special glasses for 3D images, use multi-view technology for improving 3D viewing characteristics, and has a 2D/3D switching function to express dynamic 3D contents as well as conventional 2D contents.

• Journal of The Korean Society of Grassland and Forage Science
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• v.37 no.2
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• pp.176-182
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• 2017

This study was conducted to evaluate the protein requirement for maintenance of fattening Korean black goat (Capra hircus coreanae). Six male goats with average initial body weight (BW) of $31.78{\pm}4.54kg$ and an average age of 8 months were used in this study. The experiment had a replicated duplicated $3{\times}3$ Latin square design for balancing carryover effects. In the course of the experiment, each of Black goats were fed three diets that were formulated to contain T1 (13%), T2 (16%) and T3 (19%) levels of crude protein (CP). A 14-day diet adjustment period was followed by a 5-day collection period. Dry matter intake (DMI) of groups fed diets with T2 was 966.67g/d which was higher than group fed diets with T1 and T3 were 925.14g/d and 936.08g/d each. Average daily gains (ADG) of black goats were the highest in T2(167.13g/d) But, there was no significant difference. Dietary protein levels affected the apparent digestibility of CP (p<0.05). A significant difference was found in CP intake among treatments and goats receiving T3, T2, and T1 recorded 181.23, 154.57, and 128.78g CP/d, respectively. This was excepted because CP intake is proportional to CP content of diet, which from highest to lowest was as follows: T3 (19%) > T2 (16%) > T1 (13%). Intercept of the regression equation between CP intake and CP balance indicated that maintenance CP requirement was 1.63g/BW0.75.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.7
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• pp.1250-1261
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• 2002

Many research works have validated the J-T approach to elastic-plastic crack-tip stress fields in a variety of plane strain specimens. To generalize the validity of J-T method, further investigations are however needed for more practical 3D structures than the idealized plane strain specimens. In this work, we perform 3D finite element (FE) modeling of welded plate and straight pipe, and accompanying elastic, elastic-plastic FE analyses. Manual 3D modeling is almost prohibitive, since the models contain semi-elliptical interfacial cracks which require singular elements. To overcome this kind of barrier, we develop a program generating the meshes for semi-elliptical interfacial cracks. We then compare the detailed 3D FE stress fields to those predicted with J-T two parameters. Thereby we extend the validity of J-T application to 3D structures and infer some useful informations for the design or assessment of pipe welds.

• Journal of Microbiology and Biotechnology
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• v.9 no.6
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• pp.737-743
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• 1999

A conventional thermophilic anaerobic digester was converted into a thermophilic high-rate hybrid anaerobic reactor (THAR) for treating distillery wastewater. The THAR has been operating successfully since May 1995 at a loading rate of 5.45 to $11.52{\;}kg/\textrm{m}^3/d$ (maximum of 15.02). The THAR has demonstrated a soluble Chemical Oxygen Demand (sCOD) removal efficiency of 85 to 91% and a total COD (tCOD) removal efficiency of as much as 72 to 84%. Product gas had a methane content of 59 to 68%. The tCOD removal rates were 4.31 to 5.43, 6.26 to 6.89, and 9.03 to $9.78kg{\;}tCOD/\textrm{m}^3/d$ for tapioca, com, and naked-barley wastewater, respectively. The sCOD removal rates ranged from 3.75 to 4.79,3.28 to 4.89, and 5.57 to 6.21kg $sCOD/\textrm{m}^3/d$ for tapioca, com, and naked-barley wastewater, respectively. There were unknown substances in a naked-barley distillery wastewater that were identified as being toxic for microorganisms. However, the THAR treated naked-barley wastewater continuously for 26 days, operating at an average tCOD loading of $11.08{\;}kg/\textrm{m}^3/d$without any signs of deterioration in either COD removal efficiency or gas production rate. During this period, the average removal efficiencies of tCOD and sCOD were 84% and 91%, respectively, and the gas production rate averaged 6.61 to $7.57{\;}\textrm{m}^3/\textrm{m}^3$ reactor/d which produced 0.57 to $0.69{\;}\textrm{m}^3{\;}biogas/kg{\;}tCOD_{rem}$. From tapioca and com wastewater, the reactor showed an average gas production rate of 3.18 to 3.46 and 4.91 to $5.22{\;}\textrm{m}^3/\textrm{m}^3$ reactor/d which produced 0.53 to 0.69 and 0.62 to $0.71{\;}\textrm{m}^3/kg{\;}tCOD_{rem}$, respectively.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.15 no.4
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• pp.649-659
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• 2002

For a variety of elastic-plastic stress fields of plane strain specimens, many research works verified the validity of J-T approach. To generalize the validity of J-T method, however, further investigations are needed for more practical 3D structures than the idealized geometries as plane strain specimens. In this work, selecting two main types of structures such as plate and straight pipe, we perform 3D finite element(FE) modeling, and accompanying elastic, elastic-plastic FE analyses. We then study the validity of J-T application to 3D structures, and present some useful informations for the design or assessment of pipe welds by comparing the stress fields from the detailed 3D FE analyses to those predicted with J-T two parameters.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.13 no.2
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• pp.1-4
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• 1977

The author determined the relationship between the hauling veloicty and the hydrodynamic resistance of the sablefish pot shaped conic frustum like, and induced the formulae to determine the diameter of the main line and the net horse power of the pot hauler. The results are summarized as follows: 1. The maximum hydrodynamic resistance (with its weight in water) of the pot T(kg), when the bottom webbing is covered by a cloth to imitate the catches are scattered on the bottom, is eatimated as $$ T=120v^{1.1} (0.3{\leqq}v{\leqq}0.8) $$ where v denotes the hauling velocity of the pot in m/sec. 2. When P. P. 3 strand rope is used as main line, the diameter d(mm)is recommended to satisfy the formula $$ d=72 \frac{D}{H} V^{1.1} where H denotes the depth of the fishing ground and D the intervals of the pots linked to the main in m respectively. 3. The pot hauler must displace the net horse power p(ps) of $$ P= \frac{75}{120} \frac{D}{H} v^{2.1}$$