• International Journal of Oral Biology
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• v.39 no.4
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• pp.169-176
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• 2014

A positional scanning synthetic peptide combinatorial library (PS-SCL) was screened in order to identify antimicrobial peptides against the cariogenic oral bacteria, Streptococcus mutans. Activity against Streptococcus gordonii and Aggregatibacter actinomycetemcomitans was also examined. The library was comprised of six sub-libraries with the format $O_{(1-6)}XXXXX-NH_2$, where O represents one of 19 amino acids (excluding cysteine) and X represents equimolar mixture of these. Each sub-library was tested for antimicrobial activity against S. mutans and evaluated for antimicrobial activity against S. gordonii and A. actinomycetemcomitans. The effect of peptides was observed using transmission electron microscopy (TEM). Two semi-mixture peptides, RXXXXN-$NH_2$ (pep-1) and WXXXXN-$NH_2$ (pep-2), and one positioned peptide, RRRWRN-$NH_2$ (pep-3), were identified. Pep-1 and pep-2 showed significant antimicrobial activity against Gram positive bacteria (S. mutans and S. gordonii), but not against Gram negative bacteria (A. actinomycetemcomitans). However, pep-3 showed very low antimicrobial activity against all three bacteria. Pep-3 did not form an amphiphilic ${\alpha}$-helix, which is a required structure for most antimicrobial peptides. Pep-1 and pep-2 were able to disrupt the membrane of S. mutans. Small libraries of biochemically-constrained peptides can be used to generate antimicrobial peptides against S. mutans and other oral microbes. Peptides derived from such libraries may be candidate antimicrobial agents for the treatment of oral microorganisms.

• Journal of the Korean Institute of Intelligent Systems
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• v.21 no.5
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• pp.602-608
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• 2011

In this study, a method of designing a neurointerface using neural network (NN) is proposed for controlling nonholonomic mobile robots. According to the concept of virtual master-slave robots, in particular, a partially stable inverse dynamic model of the master robot is acquired online through the NN by applying a feedback-error learning method, in which the feedback controller is assumed to be based on a PD compensator for such a nonholonomic robot. The NN for the online feedback-error learning can composed that the input layer consists of six units for the inputs $x_i$, i=1~6, the hidden layer consists of two hidden units for hidden outputs $o_j$, j=1~2, and the output layer consists of two units for the outputs ${\tau}_k$, k=1~2. A tracking control problem is demonstrated by some simulations for a nonholonomic mobile robot with two-independent driving wheels. The initial q value was set to [0, 5, ${\pi}$].

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2017.05a
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• pp.140-140
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• 2017

4륜 장착 자동차의 토크 전달은 2륜 구동, 4륜 구동 모드를 간단히 전환하는 방식(part time 4WD)과 항시 사륜 구동 모드에서 전후륜의 토크 전달비를 제어하는 방식(AWD, all wheel drive)이 있다. 경제의 발달에 따라서 취미 인구의 확대로 국내에만 180만 명의 R/C car 사용자가 있다. 이 중 2WD-4WD의 전환을 differential lock mechanism으로 구현한 수입산 모델의 가격이 1,000,000원을 호가하지만 가변 제어 방식이 아닌, 정차 후 2-4륜 구동 전환 방식을 적용하고 있으며 상대적으로 내구성이 떨어진다. DC motor의 출력이 늘어나고 배터리의 성능이 좋아진 현재 소형 RC car의 최고 속도는 80 km/h 정도로 빨라졌다. 그러나 마찰 계수가 낮은 노면(실내의 대부분 평활 처리된 복도)에서는 2륜 구동 모드의 활용도가 매우 낮다. 미끄러운 노면에서 후륜 구동 모드로는 oversteer가 발생하여 차량이 스핀하기 쉽고 전륜 구동 모드로는 understeer가 발생하여 제대로 된 코너링이 어렵다. 상시 4륜 구동 모드는 에너지 소모가 크고 전후륜이 tight coupling되어 있는 문제 때문에 일반적인 노면에서 부드러운 코너링이 잘 이루어지지 않는 문제가 있다. 본 연구에서 제안하는 방식은 그림 1와 같이 center shaft의 중간에 영구 자석으로 만들어진 토크 전달용 판이 있고 그 사이에 자계를 차폐할 수 있는 강자성체 셔터를 서보 기구에 연결하여 서보 회전각에 따라서 구동 쪽의 토크가 피구동축으로 전달되는 양을 연속 가변제어할 수 있다. 토크 전달용 판의 차폐 면적에 따른 토크 전달양을 전/후륜 바퀴의 Static torque를 통해 측정하였으며(그림 2), 공중 상태에서 즉 공기저항만을 고려한 상태에서의 RPM 회전수 차이 측정(그림3)을 통해 구동 쪽의 회전수가 피구동축으로 전달되는 양을 측정하여 연속가변 토크 제어 전달 기구의 성능을 확인하였다. 이 기구는 현재 1차적으로는 remote controller의 ch 3(ON/OFF제어 방식)에 연결하여 특정한 양의 토크를 전륜 쪽으로 보낼 수 있도록 구현이 가능하며, ch 2(PID제어 방식)에 연결하여 연속 가변 조절이 가능하도록 구현이 가능하다. 부가적으로 Arduino board를 내장하여 전후륜의 휠센서에서 입력되는 신호를 감지하여 자동적으로 전후륜에 배분되는 토크를 제어할 수 있도록 설계 중에 있다.

• Restorative Dentistry and Endodontics
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• v.23 no.2
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• pp.597-606
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• 1998

The purpose of this study was to evaluate the shear bond strength of the Compoglass Carvifil bonded on the dentin surface according to etching or non-etching and two time application or three time application of single component. Human non-carious 60 extracted 3rd molar were used. The occlusal dentin surfaces of all teeth were exposed with Diamond Wheel Saw and polished with Lapping & Polishing machine(South Bay Technology Co., U.S.A). The teeth were then distributed randomly into four groups of 15 teeth each and dentin surface were conditioned as following. Control group : Non-etching, two times application of Syntac Single Component. (According to manufacture's instruction) Experimental group 1 : Non-etching, three times application of Syntac Single Component. Experimental group : 2 Etching, two times application of Syntac Single Component. Experimental group 3 : Etching, three times application of Syntac Single Component. Compoglass were bonded to exposed dentin surfaces and all samples were placed in distilled water for 7 days. The shear bond strengths were measured by universal testing machine (SHIMADAZU AUTOGRAPH, AGS-4D., Japan). The results were as follows : 1. Experimental group 3 revealed the highest value (30.75${\pm}$4.74 MPa) and control group revealed the lowest value(14.85${\pm}$2.69 MPa). There was significant difference of shear bond strength among four groups(P<0.01) 2. The acid-etching groups (experimental group 2, 3) had higher shear bond strengths than non etching groups(control group and experimental group 1). 3. The additional application of Syntac single component groups revealed a higher bond strength than two times application groups (control group and experimental group 2).

• Geomechanics and Engineering
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• v.19 no.2
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• pp.153-165
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• 2019

A case study of monitoring and analysis of surface settlement induced by tunneling of Tabriz metro line 2 (TML2) is presented in this paper. The TML2 single tunnel has been excavated using earth pressure balanced TBM with a cutting-wheel diameter of 9.49 m since 2015. Presented measurements of surface settlements, were collected during the construction of western part of the project (between west depot and S02 station) where the tunnel was being excavated in sand and silt, below the water table and at an average axis depth of about 16 m. Settlement readings were back-analyzed using Gaussian formula, both in longitudinal and transversal directions, in order to estimate volume loss and settlement trough width factor. In addition to settlements, face support and tail grouting pressures were monitored, providing a comprehensive description of the EPB performance. Using the gap model, volume loss prediction was carried out. Also, COB empirical method for determination of the face pressure was employed in order to compare with field monitored data. Likewise, FE simulation was used in various sections employing the code Simulia ABAQUS, to investigate the efficiency of numerical modelling for the estimating of the tunneling induced-surface settlements under such a geotechnical condition. In this regard, the main aspects of a mechanized excavation were simulated. For the studied sections, numerical simulation is not capable of reproducing the high values of in-situ-measured surface settlements, applying Mohr-Coulomb constitutive law for soil. Based on results, for the mentioned case study, the range of estimated volume loss mostly varies from 0.2% to 0.7%, having an average value of 0.45%.

• Journal of the Korean Institute of Rural Architecture
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• v.26 no.2
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• pp.65-72
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• 2024

In order to analyze the impact of fine dust generated from a construction waste intermediate processing site on the surrounding areas, diverse types of samples were collected from inside the site and surrounding areas. The impact analysis results of samples are as follows. (1) Compared to the air quality management standards by the Ministry of Environment, the concentration of fine dust within the site was 30 to 46% for PM10 and 14 to 42% for PM2.5, which was not much different from the general air quality level. (2) It was found that PM10 within the site may have a partial effect on the air quality, but when the blocking facilities in the site, wheel washing facilities at vehicle entry and exit route, and sprinkler during working were maintained, the impact on the nearby area was not high. (3) In the case of PM2.5, its concentration was influenced more by the exhaust fumes from work vehicles than fine dust generated during construction waste processing. Since the PM2.5 concentrations in the site and surrounding area were not much different from the general air quality, there was little correlation with the work impact of construction waste intermediate processing sites. (4) Pb, an indicator of heavy metal components, was within 50ng/m³ in all three sites, which was 10% of the domestic management standard and equivalent to the general air quality level. The complaints from residents in nearby areas were filed using indicators based on visual and experiential information in their daily lives, so even if the survey results of environmental impact by the construction intermediate waste processing site are lower than the standard, nearby residents can feel it better than such numerical information. Therefore, specific activities to reduce find dusts should be continuously continued.

• Aerospace Engineering and Technology
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• v.13 no.2
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• pp.18-28
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• 2014

We assume that two control moment gyros are installed for space qualification in a satellite with four reaction wheels, and study the high agile maneuver method. Using high torque control moment gyros, we reduce the satellite's attitude error. After that, we activate reaction wheels to control remaining attitude error. This proposed method can avoid singularity problem of control moment gyros, and do not require gimbals' angle to calculate torque command. Through numerical simulations, we show that our method's agile performance is similar to previous method and reduce the reaction wheels' required momentum.

• Journal of Institute of Control, Robotics and Systems
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• v.13 no.11
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• pp.1092-1098
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• 2007

A mobile robot localization problem can be classified into following three sub-problems as an observation likelihood model, a motion model and a filtering technique. So far, we have developed the range sensor based, integrated localization scheme, which can be used in human-coexisting real environment such as a science museum and office buildings. From those experiences, we found out that there are several significant issues to be solved. In this paper, we focus on three key issues, and then illustrate our solutions to the presented problems. Three issues are listed as follows: (1) Investigation of design requirements of a desirable observation likelihood model, and performance analysis of our design (2) Performance evaluation of the localization result by computing the matching error (3) The semi-global localization scheme to deal with localization failure due to abrupt wheel slippage In this paper, we show the significance of each concept, developed solutions and the experimental results. Experiments were carried out in a typical modern building environment, and the results clearly show that the proposed solutions are useful to develop practical and integrated localization schemes.

• Proceedings of the KSME Conference
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• 2001.06c
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• pp.464-469
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• 2001

This work provides the biomechanical evaluations of a manual wheelchair with a bi-directional driving system. The new propulsion strategy can be accomplished by employing a special gear system that converts the oscillatory motion of a handrim into the unidirectional output motion of a wheel. A main feature of the forward. backward propulsion is to supply continuous driving torque without break. Motion. analysis has been performed through 2-dimensional image processing for measuring the kinematic properties of the upper arm and fore arm. Then, the inverse dynamics analysis has been done for obtaining the joint torques, the handrim forces and input/output powers. Results show that the output power by the forward. reverse propulsion is almost twice as much as that by conventional propulsion. Also, the new propulsion is expected to reduce the fatigues and injuries at arm joints by employing more muscle groups for movement. In conclusion, the forward. reverse propulsion can greatly improve the performances of manual wheelchairs by providing better mobility as well as by guaranteeing several advantages from a biomechanical viewpoint. Future development of a manual wheelchair optimized for the bi-directional propulsion will further improve the propulsion performances.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.14 no.6
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• pp.14-20
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• 2015

A high-speed reduction transfer case is usually employed by an excavator, wheel loader, or bulldozer. When powerful torque is required in the case of climbing steep roads or towing heavy equipment, the high-speed reduction mode of the gearbox is used. Generally, a transfer case using a spur gear type with a speed reduction system has a speed reduction ratio of 1 to 1 or 2 to 1. However, the structure of a transfer case achieved at a high speed of 1 to 1 and a low speed of 4.5 or under 5.5 to 1 with the speed reduction by use of a planetary gear type with a speed reduction system was proposed in this study. By employing a planetary gear type with a speed reduction system, the compact structure of the transfer case was achieved, and the impact or the partial defect of gear teeth was eliminated.