• Journal of the Optical Society of Korea
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• v.17 no.2
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• pp.219-223
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• 2013

The purpose of this study was to determine the relationship between the spherical equivalent visual acuity (VA) and uncorrected astigmatism. On 108 emmetropic eyes, the spherical equivalent VA was measured for cross cylindrical lens (CC lens)-induced astigmatic eyes and the VA-astigmatism relation determined. On 158 astigmatic eyes, the spherical equivalent VA and corrected astigmatism were measured and the measured values were compared with the calculated values from the VA-astigmatism relation by correlation coefficient analysis. Subsequent to that, the relationship between spherical equivalent VA and uncorrected astigmatism was made. The relationship was fitted for an exponential equation. Correlation coefficient between calculated values by equation and measured values for astigmatic eyes was 0.991 (p<0.01). The relationship between the spherical equivalent VA and the uncorrected astigmatism was decided as follows (spherical equivalent VA / uncorrected astigmatism): 1.0 / 0.25 D, 0.9 / 0.50 D, 0.8 / 0.75 D, 0.7 / 1.00 D, 0.6 / 1.25 D, 0.5 / 1.50 D, 0.4 / 2.00 D, 0.3 / 2.50 D, 0.2 / 3.00 D, 0.1 / 4.00 D, and 0.05 / 4.75 D. In conclusion, the relationship table devised from this study is a useful reference for predicting uncorrected astigmatism by measurement of decimal VA in spherical equivalent.

• Journal of Integrative Natural Science
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• v.8 no.1
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• pp.40-47
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• 2015

Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that has recently emerged as a promising target in drug discovery. It is involved in multiple cellular processes and associated with the pathogenesis of several diseases. A three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis was performed on a series of GSK-3 inhibitors to understand the structural basis for inhibitory activity. Comparative molecular field analysis (CoMFA) method was used to derive 3D-QSAR models. A reliable CoMFA model was developed using ligand-based alignment scheme. The model produced statistically acceptable results with a cross-validated correlation coefficient ($q^2$) of 0.594 and a non-cross-validated correlation coefficient ($r^2$) of 0.943. Robustness of the model was checked by bootstrapping and progressive scrambling analysis. This study could assist in the design of novel compounds with enhanced GSK-3 inhibitory activity.

• Journal of Advanced Marine Engineering and Technology
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• v.20 no.5
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• pp.30-38
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• 1996

A PIV system consisting of an image board slit into personal computer and 2-D sheet light projector is developed and related techniques to improve its performance are discussed. A grey-level cross correlation method capable of overcoming particle seeding limitation is suggested. And a sub-pixed interpolation method in determining the vector terminal is preposed by considering 8-neighbours correlation distributing patterns. Furthermore, pressure estimation from the acquired velocity vectors by applying the Poisson equation is persented with reasonable feasibility. As a practical application of the present system, evaporator flows are analysed and attained instantaneous velocity vectors reveal that the flow phenomena maintain turbulent fluctuation.

• Journal of radiological science and technology
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• v.39 no.3
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• pp.337-344
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• 2016

The purpose of this study was to evaluate the radiolucency for the phantom output to the 3D printing technology. The 3D printing technology was applied for FDM (fused deposition modeling) method and was used the material of ABS (acrylonitrile butadiene styrene) resin. The phantom was designed in cylindrical uniformity. An image uniformity was measured by a cross-sectional images of the 3D printed phantom obtained from the CT equipment. The evaluation of radiolucency was measured exposure dose by the inserted ion-chamber from the 3D printed phantom. As a results, the average of uniformity in the cross-sectional CT image was 2.70 HU and the correlation of radiolucency between PMMA CT phantom and 3D printed ABS phantom is found to have a high correlation to 0.976. In the future, this results will be expected to be used as the basis for the phantom production of the radiation quality control by used 3D printing technology.

• Journal of Radiation Protection and Research
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• v.33 no.1
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• pp.13-20
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• 2008

The flow rate measurements in a multi-phase flow pipeline were evaluated quantitatively by means of a clamp-on sealed radioisotope based on a cross correlation signal processing technique. The flow rates were calculated by a determination of the transit time between two sealed gamma sources by using a cross correlation function following FFT filtering, then corrected with vapor fraction in the pipeline which was measured by the ${\gamma}$-ray attenuation method. The pipeline model was manufactured by acrylic resin(ID. 8 cm, L=3.5 m, t=10 mm), and the multi-phase flow patterns were realized by an injection of compressed $N_2$ gas. Two sealed gamma sources of $^{137}Cs$ (E=0.662 MeV, ${\Gamma}$ $factor=0.326\;R{\cdot}h^{-1}{\cdot}m^2{\cdot}Ci^{-1}$) of 20 mCi and 17 mCi, and radiation detectors of $2"{\times}2"$ NaI(Tl) scintillation counter (Eberline, SP-3) were used for this study. Under the given conditions(the distance between two sources: 4D(D; inner diameter), N/S ratio: $0.12{\sim}0.15$, sampling time ${\Delta}t$: 4msec), the measured flow rates showed the maximum. relative error of 1.7 % when compared to the real ones through the vapor content corrections($6.1\;%{\sim}9.2\;%$). From a subsequent experiment, it was proven that the closer the distance between the two sealed sources is, the more precise the measured flow rates are. Provided additional studies related to the selection of radioisotopes their activity, and an optimization of the experimental geometry are carried out, it is anticipated that a radioisotope application for flow rate measurements can be used as an important tool for monitoring multi-phase facilities belonging to petrochemical and refinery industries and contributes economically in the light of maintenance and control of them.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.46 no.5
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• pp.95-103
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• 2009

An efficient symbol time synchronization scheme for IEEE 802.11n MIMO-OFDM based WLAN systems using cyclic shift diversity (CSD) preamble is proposed. CSD is used to prevent unintentional beamforming when the same preamble signal is transmitted through transmit antennas. However, it is difficult to find a proper starting-point of the OFDM symbol with the conventional algorithms because of time offset by multi-peaks which are result from cross-correlation of received CSD preamble with a known short training symbol. In addition, the performance of symbol time sync. is affected by AGC and packet detection position. In this paper, an optimal symbol time synch. algorithm which is composed of the boundary detection scheme between LTS and OFDM symbols, the verification scheme for enhancement of boundary detection accuracy, and the SNR-varying threshold estimation scheme is proposed. Simulation result show that the proposed algorithm has performance gains of 4.3dB in SNR compared to the conventional algorithms at the rate of 1% sync. failure probability for $2{\times}2$ MIMO-OFDM system and 18dB at 0.1% when maximum frequency offset exists. It also can be applied to $4{\times}4$ MIMO-OFDM system without any modification. Hence, it is very suitable for MIMO-OFDM WLAN systems using CSD preamble.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.26 no.2
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• pp.310-317
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• 2002

In the present study, an experimental study of natural convection in a partitioned 2D square enclosure has been carried out. The square enclosure consist of two adiabatic vertical walls and the upper cold and the lower hot walls. A partition is positioned perpendicularly at the center of the left vortical insulated wall. The PIV measurements were performed with the variations of Rayleigh number, partition length and inclination of the enclosure. The working fluid is water with Prandtl number of 6.996 at 20$\^{C}$. The captured images were analyzed by using a cross-correlation (two-frame/single-exposure) PIV method.

• Journal of the Optical Society of Korea
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• v.12 no.2
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• pp.98-102
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• 2008

Optical Coherence Tomography (OCT) is an important noninvasive medical imaging technique that can reveal subsurface structures of biological tissue. OCT has demonstrated a good correlation with histology in sufficient resolution to identify morphological changes in articular cartilage to differentiate normal through progressive stages of degenerative joint disease. Current OCT systems provide individual cross-sectional images that are representative of the tissue directly under the scanning beam, but they may not fully demonstrate the degree of degeneration occurring within a region of a joint surface. For a full understanding of the nature and degree of cartilage degeneration within a joint, multiple OCT images must be obtained and an overall assessment of the joint surmised from multiple individual images. This study presents frequency domain three-dimensional (3-D) OCT imaging of degenerative joint cartilage extracted from bovine knees. The 3-D OCT imaging of articular cartilage enables the assembly of 126 individual, adjacent, rapid scanned OCT images into a full 3-D image representation of the tissue scanned, or these may be viewed in a progression of successive individual two-dimensional (2-D) OCT images arranged in 3-D orientation. A fiber-based frequency domain OCT system that provides cross-sectional images was used to acquire 126 successive adjacent images for a sample volume of $6{\times}3.2{\times}2.5\;mm^3$. The axial resolution was $8\;{\mu}m$ in air. The 3-D OCT was able to demonstrate surface topography and subsurface disruption of articular cartilage consistent with the gross image as well as with histological cross-sections of the specimen. The 3-D OCT volumetric imaging of articular cartilage provides an enhanced appreciation and better understanding of regional degenerative joint disease than may be realized by individual 2-D OCT sectional images.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.21 no.9
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• pp.995-1004
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• 2010

In the channel-varying environment, it is very important to estimate the signal to noise ratio(SNR) of received signal and to transmit the signal effectively for the modern communication system. The performance of existing non-data-aided (NDA) SNR estimation methods are substantially degraded for high level modulation scheme such as M-ary APSK or QAM. In this paper, we propose a SNR estimation method which uses zero point auto-correlation of received signal per block and auto-/cross- correlation of decision feedback signal in OFDM system. Proposed method can be studied into two Types; Type 1 can estimate SNR by zero point auto-correlation of decision feedback signal based on the second moment property. Type 2 uses both zero point auto-correlation and cross-correlation based on the fourth moment property. In block-by-block reception of OFDM system, these two SNR estimation methods can be possible for the practical implementation due to correlation based the estimation method and they show more stable estimation performance than the previous SNR estimation methods. Also, we mathematically derive the SNR estimation expression according to computational difference of auto-/cross-correlation. Finally, Monte Carlo simulations are used to verify the proposed method.

• Bulletin of the Korean Chemical Society
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• v.27 no.12
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• pp.1969-1975
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• 2006

3D-QSAR model that correlates the biological activities with the chemical structures of quipazine derivatives acting on the serotonine transporter (SERT) was developed by comparative molecular field analysis (CoMFA). Total 8 models were constructed and a more accurate model, using close 1 $\AA$ grid spacing and StDev*Coefficients weight value gave better results. The contour maps with the best model, the resulting cross-validated correlation ($q^2$ : 0.744), and non-cross-validated correlation ($r^2$ : 0.966) indicate the steric and electrostatic environment of inhibitors in the SERT binding pocket. This study can be used as a putative picture of the pharmacophore in the design of novel and potent inhibitors.