• Journal of the Korean Society of Propulsion Engineers
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• v.16 no.1
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• pp.25-35
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• 2012

An endwall boundary layer fence technique was adapted to improve the aerothermal environment of a gas turbine passage. The shape optimization of the fence was performed to maximize the improvement. The turbine passage was simulated by a $90^{\circ}$ turning duct (ReD=360,000). The main purpose of the present investigation was to focus on finding a endwall boundary layer fence with minimum total pressure loss in the passage and heat transfer coefficient on the endwall of the duct. Anothor objective function was to minimize the area on the endwall of the duct. An approximate optimization method was used for the investigation to secure the computational efficiency. Results indicated that a significant improvement in aerodynamic environment can be achieved through the application of the fence. Improvement of the thermal environment was smaller than that of the aerodynamic enviroment.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.9
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• pp.1185-1191
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• 2010

Aged aircraft have several cracks as a results of long-term service, and these cracks affect the safety and decrease the rate of operation of the aircraft. To solve these problems, crack propagation analysis should be performed to determine the service life at fatigue critical location(FCL). It is, however, almost impossible to obtain the stress spectrum, which is crucial for crack propagation analysis of the FCLs of wing structure of aged aircraft. In this study, to analyze the fatigue crack propagation behavior at the FCL of an aged aircraft, first finite element analysis is performed for a 3D geometry model of the aircraft wing structure, which is obtained using CATIA based on the paper drawings. Then, the transfer function and stress-spectrum of the FCL are derived using the load factor data and the FEA results. Finally, the crack propagation rates of the FCL are evaluated using the commercial software, NASGRO 6.0.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.04a
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• pp.19-29
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• 1996

The neurological manifestations of AIDS include dementia, encountered even in the absence of opportunistic superinfection or malignancy. The AIDS Dementia Complex appears to be associated with several neuropathological abnormalities, including astrogliosis and neuronal injury or loss. How can HIV-1 result in neuronal damage if neurons themselves are only rarely, if ever, infected by the vitus\ulcorner In vitro experiments from several different laboratiories have lent support to the existence of HIV- and immune-related toxins. In one recently defined pathway to neuronal injury, HIV-infected macrophages/microglia as well as macrophages activated by HIV-1 envelope protein gp120 appear to secrete excitants/neurotoxins. These substances may include arachidonic acid, platelet-activating factor, free radicals (NO - and O$_2$), glutamate, quinolinate, cysteine, cytokines (TNF-${\alpha}$, IL1-B, IL-6), and as yet unidentified factors emanating from stimulated macrophages and possibly reactive astrocytes. A final common pathway for newonal suscepubility appears to be operative, similar to that observed in stroke, trauma, epilepsy, and several neurodegenerative diseases, including Huntington's disease, Parkinson's disease, and amyotrophic lateral sclerosis. This mechanism involves excessive activation of N-methyl-D-aspartate (NMDA) receptor-operated channels, with resultant excessive influx of Ca$\^$2+/ leading to neuronal damage, and thus offers hope for future pharmacological intervention. This chapter reviews two clinically-tolerated NMDA antagonists, memantine and nitroglycerin; (ⅰ) Memantine is an open-channel blocker of the NMDA-associated ion channel and a close congener of the anti-viral and anti-parkinsonian drug amantadine. Memantine blocks the effects of escalating levels of excitotoxins to a greater degree than lower (piysiological) levels of these excitatory amino acids, thus sparing to some extent normal neuronal function. (ⅱ) Niuoglycerin acts at a redox modulatory site of the NMDA receptor/complex to downregulate its activity. The neuroprotective action of nitroglycerin at this site is mediated by n chemical species related to nitric oxide, but in a higher oxidation state, resulting in transfer of an NO group to a critical cysteine on the NMDA receptor. Because of the clinical safety of these drugs, they have the potential for trials in humans. As the structural basis for redox modulation is further elucidated, it may become possible to design even better redox reactive reagents of chinical value. To this end, redox modulatory sites of NMDA receptors have begun to be characterized at a molecular level using site-directed mutagenesis of recombinant subunits (NMDAR1, NMDAR2A-D). Two types of redox modulation can be distinguished. The first type gives rise to a persistent change in the functional activity of the receptor, and we have identified two cysteine residues on the NMDARI subunit (#744 and #798) that are responsible for this action. A second site, presumably also a cysteine(s) because <1 mM N-ethylmaleimide can block its effect in native neurons, underlies the other, more transient redox action. It appears to be at this, as yet unidentified, site on the NMDA receptor that the NO group acts, at least in recombinant receptors.

• Journal of Astronomy and Space Sciences
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• v.29 no.2
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• pp.233-244
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• 2012

The Korea Astronomy and Space Science Institute and the Department of Astronomy at the University of Texas at Austin are developing a near infrared wide-band high resolution spectrograph, immersion grating infrared spectrometer (IGRINS). The compact white-pupil design of the instrument optics uses seven cryogenic mirrors, including three aspherical off-axis collimators and four flat fold mirrors. In this study, we introduce the optomechanical mount designs of three off-axis collimating mirrors and one flat slit-viewer fold mirror. Two of the off-axis collimators are serving as H and K-band pupil transfer mirrors, and are designed as system alignment compensators in combination with the H2RG focal plane array detectors in each channel. For this reason, the mount designs include tip-tilt and parallel translation adjustment mechanisms to properly perform the precision alignment function. This means that the off-axis mirrors' optomechanical mount designs are among the most sensitive tasks in all IGRINS system hardware. The other flat fold mirror is designed within its very limitedly allowed work space. This slit-viewer fold mirror is mounted with its own version of the six-point kinematic optics mount. The design work consists of a computer-aided 3D modeling and finite element analysis (FEA) technique to optimize the structural stability and the thermal behavior of the mount models. From the structural and thermal FEA studies, we conclude that the four IGRINS mirror mounts are well designed to meet all optical stability tolerances and system thermal requirements.

• Journal of the Korean Geotechnical Society
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• v.31 no.2
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• pp.47-63
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• 2015

A fundamental study of drilled shafts subjected to lateral cyclic loading in weathered soil was carried out based on field tests and numerical analysis. The emphasis was given on quantifying the cyclic p-y curve function from lateral cyclic loading tests and three-dimensional finite element analysis. Lateral cyclic loading tests and three-dimensional finite element analysis were carried out to investigate the behavior of drilled shafts according to the direction of cyclic loading. Based on the field tests and numerical analysis, a modified lateral load transfer relationship and design chart with degradation factors were proposed by considering the characteristics of cyclic loading. It was found that the prediction by the proposed p-y curve function is in good agreement with the general trends observed by in-situ measurements, and it represents a practical improvement in the prediction of lateral displacement and bending moment distribution of drilled shafts subjected to cyclic loading.

• Journal of the Earthquake Engineering Society of Korea
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• v.3 no.3
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• pp.63-74
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• 1999

A sliding mode fuzzy control (SMFC) algorithm is presented for vibration of large structures. Rule-base of the fuzzy inference engine is constructed based on the sliding mode control, which is one of the nonlinear control algorithms. Fuzziness of the controller makes the control system robust against the uncertainties in the system parameters and the input excitation. Non-linearity of the control rule makes the controller more effective than linear controllers. Design procedure based on the present fuzzy control is more convenient than those of the conventional algorithms based on complex mathematical analysis, such as linear quadratic regulator and sliding mode control(SMC). Robustness of presented controller is illustrated by examining the loop transfer function. For verification of the present algorithm, a numerical study is carried out on the benchmark problem initiated by the ASCE Committee on Structural Control. To achieve a high level of realism, various aspects are considered such as actuator-structure interaction, modeling error, sensor noise, actuator time delay, precision of the A/D and D/A converters, magnitude of control force, and order of control model. Performance of the SMFC is examined in comparison with those of other control algorithms such as $H_{mixed 2/{\infty}}$ optimal polynomial control, neural networks control, and SMC, which were reported by other researchers. The results indicate that the present SMFC is an efficient and attractive control method, since the vibration responses of the structure can be reduced very effectively and the design procedure is simple and convenient.

• Korean Journal of Agricultural Science
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• v.8 no.2
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• pp.195-202
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• 1981

The return of water to the atmosphere from water, soil and vegetation surface is one of the most important aspects of hydrological cycle, and the seasonal trend of variation of river basin evaporation is also meaningful in the longterm runoff analysis for the irrigation and water resources planning. This paper has been prepared to show some imformation to estimate the monthly river basin evaporation from pan evaporation, potential evaporation, regional evaporation and temperature through the comparison with river basin evaporation derived from water budget method. The analysis has been carried out with the observation data of Yongdam station in the Geum river basin for five year. The results are summarized as follows and these would be applied to the estimation of river basin evaporation and longterm runoff in ungaged station. 1. The ratio of pan evaporation to river basin evaporation ($E_w/E_{pan}$) shows the most- significant relation at the viewpoint of seasonal trend of variation. River basin evaporation could be estimated from the pan evaporation through either Fig. 9 or Table-7. 2. Local coefficients of cloudness effect and wind function has been determined to apply the Penman's mass and energy transfer equation to the estimation of river basin evaporation. $R_c=R_a(0.13+0.52n/D)$ $E=0.35(e_s-e)(1.8+1.0U)$ 3. It seems that Regional evaporation concept $E_R=(1-a)R_C-E_p$ has kept functional errors due to the inapplicable assumptions. But it is desirable that this kind of function which contains the results of complex physical, chemical and biological processes of river basin evaporation should be developed. 4. Monthly river basin evaporation could be approximately estimated from the monthly average temperature through either the equation of $E_w=1.44{\times}1.08^T$ or Fig. 12 in the stations with poor climatological observation data.

• Tuberculosis and Respiratory Diseases
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• v.59 no.4
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• pp.374-379
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• 2005

Background : The single-breath carbon monoxide diffusion capacity (DLCO) and the per unit alveolar volume (KCO; $D_LCO/VA$) gave discordant values when there was an abnormal alveolar volume (VA). However, the clinical significance of the discordant values in patients with airflow limitation has not been examined. This study investigated the $D_LCO$ and KCO changes after improving the airflow limitation. Methods : The baseline $D_LCO$ and KCO with lung volume were measured in patients with an airflow obstruction. The effective alveolar volume was measured using the single-breath $CH_4$ dilution method. The patients divided into two groups according to the baseline values: (1) increased KCO in comparison with the $D_LCO$ (high discordance) (2) decreased or not increased KCO in comparison with the $D_LCO$ (low discordance). The diffusion capacity and lung volume were measured after treatment. Results : There was no significant difference in the baseline lung volumes including the $FEV_1$ and FVC between the two groups. The $FEV_1$ and FVC were significantly increased in the high discordance group compared with the low discordance group after treating the airflow limitation. The $D_LCO$ and alveolar volume were significant higher in the high discordance group compared with the low discordance group while the TLC was not. Conclusion : The discordance between the $D_LCO$ and KCO could be translated into an airflow reversibility in patients with an airflow limitation.

• KIEE International Transaction on Systems and Control
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• v.2D no.2
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• pp.78-91
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• 2002

In the thermal power plant, there are six manipulated variables: main steam flow, feedwater flow, fuel flow, air flow, spray flow, and gas recirculation flow. There are five controlled variables: generator output, main steam pressure, main steam temperature, exhaust gas density, and reheater steam temperature. Therefore, the thermal power plant control system is a multinput and output system. In the control system, the main steam temperature is typically regulated by the fuel flow rate and the spray flow rate, and the reheater steam temperature is regulated by the gas recirculation flow rate. However, strict control of the steam temperature must be maintained to avoid thermal stress. Maintaining the steam temperature can be difficult due to heating value variation to the fuel source, time delay changes in the main steam temperature versus changes in fuel flow rate, difficulty of control of the main steam temperature control and the reheater steam temperature control system owing to the dynamic response characteristics of changes in steam temperature and the reheater steam temperature, and the fluctuation of inner fluid water and steam flow rates during the load-following operation. Up to the present time, the Proportional-Integral-Derivative Controller has been used to operate this system. However, it is very difficult to achieve an optimal PID gain with no experience, since the gain of the PID controller has to be manually tuned by trial and error. This paper focuses on the characteristic comparison of the PID controller and the modified 2-DOF PID Controller (Two-Degrees-Freedom Proportional-Integral-Derivative) on the DCS (Distributed Control System). The method is to design an optimal controller that can be operated on the thermal generating plant in Seoul, Korea. The modified 2-DOF PID controller is designed to enable parameters to fit into the thermal plant during disturbances. To attain an optimal control method, transfer function and operating data from start-up, running, and stop procedures of the thermal plant have been acquired. Through this research, the stable range of a 2-DOF parameter for only this system could be found for the start-up procedure and this parameter could be used for the tuning problem. Also, this paper addressed whether an intelligent tuning method based on immune network algorithms can be used effectively in tuning these controllers.

• Journal of Periodontal and Implant Science
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• v.36 no.2
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• pp.531-554
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• 2006

Oral implants must fulfill certain criteria arising from special demands of function, which include biocompatibility, adequate mechanical strength, optimum soft and hard tissue integration, and transmission of functional forces to bone within physiological limits. And one of the critical elements influencing the long-term uncompromise functioning of oral implants is load distribution at the implant- bone interface, Factors that affect the load transfer at the bone-implant interface include the type of loading, material properties of the implant and prosthesis, implant geometry, surface structure, quality and quantity of the surrounding bone, and nature of the bone-implant interface. To understand the biomechanical behavior of dental implants, validation of stress and strain measurements is required. The finite element analysis (FEA) has been applied to the dental implant field to predict stress distribution patterns in the implant-bone interface by comparison of various implant designs. This method offers the advantage of solving complex structural problems by dividing them into smaller and simpler interrelated sections by using mathematical techniques. The purpose of this study was to evaluate the stresses induced around the implants in bone using FEA, A 3D FEA computer software (SOLIDWORKS 2004, DASSO SYSTEM, France) was used for the analysis of clinical simulations. Two types (external and internal) of implants of 4.1 mm diameter, 12.0 mm length were buried in 4 types of bone modeled. Vertical and oblique forces of lOON were applied on the center of the abutment, and the values of von Mises equivalent stress at the implant-bone interface were computed. The results showed that von Mises stresses at the marginal. bone were higher under oblique load than under vertical load, and the stresses were higher at the lingual marginal bone than at the buccal marginal bone under oblique load. Under vertical and oblique load, the stress in type I, II, III bone was found to be the highest at the marginal bone and the lowest at the bone around apical portions of implant. Higher stresses occurred at the top of the crestal region and lower stresses occurred near the tip of the implant with greater thickness of the cortical shell while high stresses surrounded the fixture apex for type N. The stresses in the crestal region were higher in Model 2 than in Model 1, the stresses near the tip of the implant were higher in Model 1 than Model 2, and Model 2 showed more effective stress distribution than Model.