• Title/Summary/Keyword: 2D 변형

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THE EFFECTS OF TGF-$\beta$1 ON THE BONE REGENERATION IN GUINEA PIG MANDIBLE (형질변형성장인자가 손상골 재생능에 미치는 영향에 관한 실험적 연구)

  • Lee Byung-Do;Hwang Eui-Hwan;Lee Sang-Rae;Hong Jung-Pyo
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.25 no.2
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    • pp.423-435
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    • 1995
  • The purpose of this study was to observe the effect of TGF-βl, which promotes differentiation and proliferation of osteoblasts, on bone regeneration. Experimental bone defects that measured 3 mm in diameter were created on the mandibles of guinea pig by removal of bone with the use of trephine burs. In one side of mandibular body, the experimental groups, bone defects were grafted with Biogran(Orthovita Co., U.S.A) and TGF-β1(R&D System Co., U.SA). In the remaining side of the mandiblar body, the control groups, bone defects were grafted with only Biogran. Guinea pigs in the control and experimental groups were serially terminated by fours on the 3 days, the 1 week, the 2 weeks, the 3 weeks, and the 4 weeks after experiment, and both sides of the mandibular bodies were removed and fixed with 10% neutral formalin. They were decalcified and embedded in paraffin as using the usual method. The specimen sectioned and stained with hematoxylin and eosin. Also, they were radiographed with a soft X -ray apparatus. The obtained results were as follows; 1. Hemorrhagic condition, observed in the granulation tissues, disappeared on the 1 week after experiment in both groups, and more prominent in the experimental group. The granulation tissues of the experimental group had larger number of cells than those of the control group. 2. Osteoblastic differentiation in the margin of grafted material and adjacent bone was observed on the 1 week after experiment in both groups. Also, bone formation was observed in immature form on the 1 week after experiment. and more prominent in the experimental group. 3. In the polarizing microscopic examination, bone matrix was very loose on the 1 week after experiment, but increase in density with time, and more prominent in the experimental group. 4. In the microradiographic examination, newly formed bone was observed in the experimental group on the 2 weeks after experiment, and this was observed earlier than in the control group. Newly formed bone was increased with time and defected area was markedly decreased on the 4 weeks after experiment.

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Usefulness of auditory brainstem response as early predictor of kernicterus in early breast-feeding jaundice (조기 모유 황달에서 핵황달의 조기 예측도구로서의 청성 뇌간유발 반응 검사의 유용성)

  • Jang, Jae Won;Lee, Gil Sang;Song, Dae Keun;Kim, Sung Hee;Kim, Won Duck;Lee, Sang Geel
    • Clinical and Experimental Pediatrics
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    • v.50 no.9
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    • pp.848-854
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    • 2007
  • Purpose : The present study examined the etiology and risk factors of the early breast-feeding jaundice and the usefulness of auditory brainstem response test as early predictor of kernicterus. Methods : Medical records of neonatal jaundice in newborn admitted to Daegu Fatima Hospital between September 2005 and May 2006 were analyzed prospectively. Infants were grouped according to feeding method : breast feeding group (breast feeding only, n=23), mixed feeding group (breast feeding mainly plus addition of fomula feeding, n=13). Results : There were no significant differences in gestational age, birth weight, sex, duration of phototherapy, serum bilirubin and hemolytic evidence between the two study groups. First visiting day of life at out patient department was significantly delayed in breast feeding group ($8.7{\pm}3.6day$) compared to mixed feeding group ($6.0{\pm}1.9$) (P=0.009). Weight loss was significantly severe in breast feeding group compared to mixed feeding group (P<0.05). In auditory brainstem response test, loss of Wave V in 3 cases was observed and recoverd after blood exchange transfusion in follow up test.Wave III latency had significant correlation to serum bilirubin in auditory brainstem response test (70 dB) (P=0.002). Conclusion : Our study suggest that further education about breast feeding and follow up within the first postnatal week would be necessary for early detection and prevention of early breast-feeding jaundice. Test of serum bilirubin and auditory brainstem response would be helpful in determination of blood exchange transfusion.

Diagonalized Approximate Factorization Method for 3D Incompressible Viscous Flows (대각행렬화된 근사 인수분해 기법을 이용한 3차원 비압축성 점성 흐름 해석)

  • Paik, Joongcheol
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.31 no.3B
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    • pp.293-303
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    • 2011
  • An efficient diagonalized approximate factorization algorithm (DAF) is developed for the solution of three-dimensional incompressible viscous flows. The pressure-based, artificial compressibility (AC) method is used for calculating steady incompressible Navier-Stokes equations. The AC form of the governing equations is discretized in space using a second-order-accurate finite volume method. The present DAF method is applied to derive a second-order accurate splitting of the discrete system of equations. The primary objective of this study is to investigate the computational efficiency of the present DAF method. The solutions of the DAF method are evaluated relative to those of well-known four-stage Runge-Kutta (RK4) method for fully developed and developing laminar flows in curved square ducts and a laminar flow in a cavity. While converged solutions obtained by DAF and RK4 methods on the same computational meshes are essentially identical because of employing the same discrete schemes in space, both algorithms shows significant discrepancy in the computing efficiency. The results reveal that the DAF method requires substantially at least two times less computational time than RK4 to solve all applied flow fields. The increase in computational efficiency of the DAF methods is achieved with no increase in computational resources and coding complexity.

Studies on the Enzymatic Partial Hydrolysis of Soybean Protein Isolates (효소처리에 의한 분리대두 단백질의 부분 가수분해에 관한 연구)

  • Lee, Cherl-Ho;Kim, Chan-Shick;Lee, Sam-Pin
    • Korean Journal of Food Science and Technology
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    • v.16 no.2
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    • pp.228-234
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    • 1984
  • A partial hydrolysis of soybean protein isolate was carried out by using pepsin and trypsin. The degree of hydrolysis was evaluated by chemical analysis, viscometric measurements and gel electrophoresis. The functional properties of the hydrolyzates such as flow behavior, emulsion properties and foaming properties were evaluated. A selective hydrolysis of 11S protein fraction by pepsin was observed from the SDS-PAG electrophoresis. The changes in the molecular weight distribution by different conditions of enzyme hydrolysis were evaluated. The changes in the intrinsic viscosity of the protein hydrolylate by reaction time were highly correlated to the contents of TCA soluble protein and 0.03 M $CaCl_2$ soluble nitrogen. The degree of hydrolysis ($DH_{TCA}$, $DH_{Ca}$) were used to evaluate the effect of enzyme treatment on the functional properties of the hydrolyzate. The apparent viscosity and emulsion capacity and stability of the protein solution decreased as DH increased, while the foaming capacity increased linearly with the increasing DH.

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Development Model of the Foxglove Aphid, Aulacorthum solani (Kaltenbach) on Lettuce (상추에서의 싸리수염진딧물(Aulacorthum solani)의 발육과 발육모형)

  • Lee, Sang-Guei;Kim, Hyeong-Hwan;Kim, Tae-Heung;Park, Gil-Jun;Kim, Kwang-Ho;Kim, Ji-Soo
    • Korean journal of applied entomology
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    • v.47 no.4
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    • pp.359-364
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    • 2008
  • The development of Aulacorthum solani (Kaltenbach) was studied at temperatures ranging from 12.5 to $27.5^{\circ}C$ under $65{\pm}5%$ RH, and a photoperiod of 16:8 (L:D). Mortality of $1st{\sim}2nd$ nymph was higher than that of $3rd{\sim}4th$ nymph at the most temperature ranges whereas at high temperature of $27.5^{\circ}C$, more $3{\sim}4th$ nymph stage individuals died. The total developmental time ranged from 16.9 days at $12.5^{\circ}C$ to 6.6days at $22.5^{\circ}C$, suggesting that higher the temperature, faster the development. However, at higher temperature of $25^{\circ}C$ the development took 7.4 days. The lower developmental threshold temperature and effective accumulative temperatures for the total immature stage were $0.08^{\circ}C$ and 162.8 day-degreeslated development. The nonlinear shape of temperature rewas well described by the modified Sharpe and DeMichele model. When the normalized cumulative frequency distributions of developmental times for each life stage were fitted to the three-parameter Weibull function, attendance of shortened developmental times was apparent with in $1{\sim}2nd$ nymph, $3{\sim}4th$ nymph, and total nymph stages in descending order. The coefficient of determination $r^2$ ranged between 0.86 and 0.91.

Comparison of Sea Level Data from TOPEX/POSEIDON Altimeter and in-situ Tide Gauges in the East Asian Marginal Seas (동아시아 주변해역에서의 TOPEX/POSEIDON 고도 자료와 현장 해수면 자료의 비교)

  • Youn, Yong-Hoon;Kim, Ki-Hyun;Park, Young-Hyang;Oh, Im-Sang
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.5 no.4
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    • pp.267-275
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    • 2000
  • In an effort to assess the reliability of satellite altimeter system, we conducted a comparative analysis of sea level data that were collected using the TOPEX/POSEIDON (T/P) altimeter and the 10 tide gauge (TG) stations in the satellite passing track. The analysis was made using data sets collected from marginal sea regions surrounding the Korean Peninsula at T/P cycles of 2 to 230, which correspond to October 1992 to December 1998. Because of strong tidal activity in the study area, treatment of tidal errors is a very critical step in data processing. Hence in the computation of dynamic heights from the Tn data, we adapted the procedures of Park and Gamberoni (1995) to reduce errors associated with it. When these T/P data were treated, the alias periods of M$_2$, S$_2$, and K$_1$ constitutions were found at 62.1, 58.7, and 173 days. The compatibility of the T/P and TG data sets were examined at various filtering periods. The results indicate that the low-frequency signal of Tn data can be interpreted more safely with longer filtering periods (such as up to the maximum selected values of 200 days). When RMS errors for 200-day low-pass filter period was compared among the whole 10 tidal stations, the values spanned in the range of 2.8 to 6.7 cm. The results of correlation analysis at this filtering period also showed a strong agreement between the Tn and TG data sets over the whole stations investigated (e.g., P values consistently less than 0.0001). According to our analysis, we conclude that the analysis of surface sea level using satellite altimeter data can be made safely and reasonably long filtering periods such as 200 days.

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Development and Adult Life Span of Aphidoletes aphidimyza (Rondani) (Diptera: Cecidomyiidae) Fed on the Melon Aphid, Aphis gossypii Glover or the Green Peach Aphid, Myzus persicae($S\"{u}lzer$) (Homoptera: Aphididae) (목화진딧물(Aphis gossypii)과 복숭아혹진딧물(Myzus persicae) (Homoptera: Aphididae)을 먹이로 한 진디혹파리[Aphidoletes aphidimyza (Rondani)] (Diptera: Cecidomyiidae)의 발육 및 성충수명)

  • Kim Tae-Heung;Kim Ji-Soo
    • Korean journal of applied entomology
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    • v.43 no.4 s.137
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    • pp.297-304
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    • 2004
  • The development of Aphidoletes aphidimyza, an aphidophagous gall midge, was studied at various constant temperatures ranging from 15 to $35^{\circ}C$, with $65{\pm}5\%$ RH, and a photo-period of 16L:8D. When A. aphidimyra was fed either on Aphis gossypii or Myzus persicae, it took 43.9 and 44.5 days, respectively, to develop from egg to pupa at $15^{\circ}C$, whereas at $25^{\circ}C$, 14.3 and 15.8 days. The developmental zero was 10.7 and $10.0^{\circ}C$, respectively, while the effective accumuative temperatures were 210.8 and 245.5 day-degrees. The nonlinear shape of temperature-dependent development, shown by A. aphidimyza when fed on either species of the aphids, was well described by the modified Sharpe and DeMichele model. When distribution model of completion time of development for each growth stage was expressed as physiological age and fitted to the Weibull fuction, the completion time of development gradually shortened from egg to larva, and to pupa. In addition, the coefficient of determination $r^2$ ranged between 0.86-0.93 and 0.85-0.94, respectively providing a good approximation of cumulative developmental rates. The life span of adult was 8.7 and 9.2 days at $15^{\circ}C$, and 3.1 and 2.7 days at $30^{\circ}C$, respectively. Egg incubation period was relatively short at $35^{\circ}C$ but hatchability was less than $50\%$ and the mortality of the larva at $35^{\circ}C$ reached $100\%$. At $30^{\circ}C$, the time of development lengthened and the adult longevity was short suggesting ill effect of high temperatures. Even though the life span of adults at $15^{\circ}C$ was relatively long, none moved freely in the rearing cage and no oviposition occurred. Accordingly, in case A. aphidimyza is adopted to suppress phytophagus aphid populations, it could be applicable to cropping systems with ambient temperatures above $20^{\circ}C$ and below $30^{\circ}C$. Within this range, A. aphidimyza adults was observed to be active and oviposit fully.

Analysis of Pull-out Behavior of Tunnel-type Anchorage for Suspended Bridge Using 2-D Model Tests and Numerical Analysis (2차원 모형실험 및 수치해석을 통한 현수교 터널식 앵커리지의 인발거동 특성 분석)

  • Seo, Seunghwan;Park, Jaehyun;Lee, Sungjune;Chung, Moonkyung
    • Journal of the Korean Geotechnical Society
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    • v.34 no.10
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    • pp.61-74
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    • 2018
  • In this study, the pull-out behavior of tunnel type anchorage of suspension bridges was analyzed based on results from laboratory size model tests and numerical analysis. Tunnel type anchorage has found its applications occasionally in both domestic and oversea projects, therefore design method including failure mode and safety factor is yet to be clearly established. In an attempt to improve the design method, scaled model tests were conducted by employing simplified shapes and structure of the Ulsan grand bridge's anchorage which was the first case history of its like in Korea. In the model tests, the anchorage body and the surrounding rocks were made by using gypsum mixture. The pull-out behavior was investigated under plane strain conditions. The results of the model tests showed that the tunnel type anchorage underwent wedge shape failure. For the verification of the model tests, numerical analysis was carried out using ABAQUS, a finite element analysis program. The failure behavior predicted by numerical analysis was consistent with that by the model tests. The result of numerical analysis also showed that the effect of Poisson's ratio was negligible, and that a plugging type failure mode could occur only when the strength of the surrounding rocks was 10 times larger than that of anchorage body.

A Study on Planning Car Interior Design through Two Dimensional Lay-Out (2D LAY-OUT을 통한 자동차 실내디자인 계획 방법 연구)

  • 유연식
    • Archives of design research
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    • v.11 no.2
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    • pp.215-226
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    • 1998
  • As late as middle of 1980s, what was referred to as new model cars consisted, on the premise of a standardized packaging layout, principally of the endeavor to transform their style images by changing little by little the form of layouts almosts similar to or with larger bodies than those of the old model ones. Afterwards even in the period of competition of engeineering and mechanical body styles for reducing fuel cost and improving comfortability in riding, the standardized packaging layout did not change visibly, simply trying to ameliorating commercialism through high output and high efficacy on the engineering part. Today the sudden prevalent motorization in every walk of life has brought about the development of the car industry, thus producing surplus supply and technical standardization. This phenomenon of technical standardization leads the concept of the renovation of car design to a way quite different from that of the past and so may be said to be confronted with an era that requires genuine-sense car design in a way. It seems that interior design plans are of much more importance than external shapes. This is because the effort for enhancing comfortability to keep car passengers' needs of transportation is one of the essences of car design. The objective of this study consists in inquiring into how to plan motorcar interior design, an essential prerequisite in determining the external or of a car, obtaining data needed via analysis of interior design plans of the car models that have won favorable criticism from consumers, thus contributing to the use of the data obtained for reference in car design activities in a genuine sense.

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A Design of the UWB Bandpass Filter with a Good Performance of the Stopband, and Notched Band in Passband (우수한 차단 대역 특성과 통과 대역 내에 저지 대역을 갖는 UWB 대역 통과 필터 설계)

  • An, Jae-Min;Kim, Yu-Seon;Pyo, Hyun-Seong;Lee, Hye-Sun;Lim, Yeong-Seog
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.21 no.1
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    • pp.28-35
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    • 2010
  • In this paper, we designed and fabricated a ultra-wideband(UWB) bandpass filter with a good performance of a stopband, and a notched band in passband. The transformed equivalent circuit of the highpass filter was realized by distributed element. A wide-passband with 3-dB fractional bandwidth of more than 100 % was achieved by using optimum response of the HPF. For improving lower and upper stopband characteristic, a cross coupling between feed lines was employed, which was analyzed by desegmentation technique. In order to reject interference of Wireless LAN and Hyper LAN(5.15~5.825 GHz), the narrow notched(rejection) band was realized by a spurline. The fabricated BPF indicated the passband from 3.1 to 10.55 GHz and the flat group delay of less than 0.94 ns over the entire passband except the rejection band. The filter shown sharp attenuation both inside and outside the band and notched band from 5.2 to 6.12 GHz.