• Anatomy & Biological Anthropology
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• v.31 no.4
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• pp.151-158
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• 2018

The intervertebral foramen is formed by two adjacent vertebrae and an intervertebral disc. Previous studies examining the foramen have been performed using various methods. The author obtained characteristics of the intervertebral foramen based on silicon mold. The author used 18 cadavers and dissected the lumbar intervertebral foramen. First, positional levels of the spinal nerve in the intervertebral foramen were measured. Second, after being removed all tissues covering the intervertebral, bony foramen was filled with melted silicon to mold the cross section. Subsequently, the solidified silicon mold was removed and stamped on a paper. The paper was scanned and analyzed area, perimeter, height and width of the intervertebral foramen on a computer. Area (average, $9.43mm^2$) and perimeter (average, 48.02 mm) did not show any statistical significant pattern for any lumbar vertebral levels. However, the height and width significantly differed at the fifth lumbar vertebra, which had the shortest height (the fifth, 13.00 mm; average, 15.78 mm) and longest width (the fifth, 8.61 mm; average, 7.87 mm), although there were similar patterns in case of area and perimeter of the first to fourth lumbar vertebra. Height had a decrease tendency while width had an increase tendency both from the second to fifth lumbar vertebra. Spinal nerves went through near the intervertebral disc level from the first to fourth lumbar vertebra, although they passed below the disc at the fifth level. This study provides a different view of methodology for the 3-dimensional aspect for the intervertebral foramen. Results of this study may indicate that height and width of the intervertebral foramen changed along all lumbar vertebral levels; nevertheless, area and perimeter of the intervertebral foramen remained constant.

• Korean journal of applied entomology
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• v.58 no.1
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• pp.9-13
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• 2019

Nematode-trapping fungi use various specialized traps to capture nematodes. A fungus that can capture nematodes in three dimensional adhesive networks was isolated from the soil around the root of Cucumis melo L. (Oriental melon) in Seongju, Korea. The conidiophores were found to be septate, hyaline, erect and $290-528(342.8){\mu}m$ high. It produces obovoid shape and 1-3 septate (commonly 2-septate) conidia with a size of $30.5{\times}20.3{\mu}m$. Molecular analysis of 5.8 S rDNA displayed 99% similarity to Arthrobotrys sinensis. On the basis of morphological, morphometric and molecular studies, the fungus was identified as A. sinensis. It is the first report in Korea which can be one of biological control resource of plant-parasitic nematode.

• Tunnel and Underground Space
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• v.29 no.4
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• pp.262-279
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• 2019

In the engineering barriers of high-level radioactive waste disposal, gases could be generated through a number of processes. If the gas production rate exceeds the gas diffusion rate, the pressure of the gas increases and gases could migrate through the bentonite buffer. Because people and the environment can be exposed to radioactivity, it is very important to clarify gas migration in terms of long-term integrity of the engineered barrier system. In particular, it is necessary to identify the hydro-mechanical mechanism for the dilation flow, which is a very important gas flow phenomenon only in medium containing large amounts of clay materials such as bentonite buffer, and to develop and validate new numerical approach for the quantitative evaluation of the gas migration phenomenon. Therefore, in this study, we developed a two-phase flow model considering the mechanical damage model in order to simulate the gas migration in the engineered barrier system, and validated with 1D gas flow modelling through saturated bentonite under constant volume boundary conditions. As a result of numerical analysis, the rapid increase in pore water pressure, stress, and gas outflow could be simulated when the dilation flow was occurred.

• Journal of Microbiology and Biotechnology
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• v.31 no.7
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• pp.933-941
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• 2021

Ginsenoside Rg4 is a rare ginsenoside that is naturally found in ginseng, and exhibits a wide range of biological activities including antioxidant and anti-inflammatory properties in several cell types. The purpose of this study was to use an in vivo model of hair follicle (HF)-mimic based on a human dermal papilla (DP) spheroid system prepared by three-dimensional (3D) culture and to investigate the effect of Rg4 on the hair-inductive properties of DP cells. Treatment of the DP spheroids with Rg4 (20 to 50 ㎍/ml) significantly increased the viability and size of the DP spheres in a dose-dependent manner. Rg4 also increased the mRNA and protein expression of DP signature genes that are related to hair growth including ALP, BMP2, and VCAN in the DP spheres. Analysis of the signaling molecules and luciferase reporter assays further revealed that Rg4 induces the activation of phosphoinositide 3-kinase (PI3K)/AKT and the inhibitory phosphorylation of GSK3β, which activates the WNT/β-catenin signaling pathway. These results correlated with not only the increased nuclear translocation of β-catenin following the treatment of the DP spheres with Rg4 but also the significant elevation of mRNA expression of the downstream target genes of the WNT/β-catenin pathway including WNT5A, β-catenin, and LEF1. In conclusion, these results demonstrated that ginsenoside Rg4 promotes the hair-inductive properties of DP cells by activating the AKT/GSK3β/β-catenin signaling pathway in DP spheres, suggesting that Rg4 could be a potential natural therapy for hair growth.

• Journal of the Institute of Convergence Signal Processing
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• v.22 no.4
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• pp.185-192
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• 2021

Various methods have been proposed to determine the defect detection of welding bead, and recently sensor data and image data inspection have been steadily announced. There are advantages that sensor data inspection is highly accurate, and two-dimensional-based image data inspection is able to determine the position of the welding bead. However, when analyzing only with sensor data, it is difficult to determine whether the welding has been performed at the correct position. On the other hand, the image data inspection does not have high accuracy due to noise and measurement errors. In this paper, we propose a method that can complement the shortcomings of each inspection method and increase its advantages to improve accuracy and speed up inspection by fusing sensor data inspection which are average current, average volt, and mixed gas data, and image data inspection methods and is implemented as software. In addition, it is intended to allow users to conveniently and intuitively analyze and grasp the results by performing analysis using a graphical user interface(GUI) and checking the data and inspection results used for the inspection. Sensor inspection is performed using the characteristics of each sensor data, and image data is inspected by applying a morphology geodesic active contour algorithm. The experimental results showed 98% accuracy, and when performing the inspection on the four image data, and sensor data the inspection time was about 1.9 seconds, indicating the performance of software that can be used as a real-time inspector in the welding process.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.42 no.4
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• pp.537-548
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• 2022

It is important to design the pavement thickness considering heavy-duty traffic loads, which can cause excessive stress and strain in the pavement. Port-rear roads and industrial roads have many problems due to early stress in pavement because these have a higher ratio of heavy loads than general roads such as national roads and expressways. Internationally, composite pavement has been widely applied in pavement designs in heavy-duty areas. Composite pavement is established as an economic pavement type that can increase the design life by nearly double compared to that of existing pavement while also decreasing maintenance and user costs. This study suggests a thickness design method for composite pavement using roller-compacted concrete as a base material to ensure long-term serviceability in heavy-duty areas such as port-rear roads and industrial roads. A three-dimensional finite element analysis was conducted to investigate the mechanical behavior and the long-term pavement performance ultimately to suggest a thickness design method that considers changes in the material properties of the roller-compacted concrete (RCC) base layer. In addition, this study presents a user-friendly catalog design method for RCC-base composite pavement considering the concept of linear damage accumulation for each container trailer depending on the season.

• Journal of Navigation and Port Research
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• v.46 no.6
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• pp.471-482
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• 2022

This study aims to investigate the characteristics of wave generation in a deep ocean engineering basin and to develop a meta-model of the transfer function of the wavemaker that reflects the geometric characteristics of the deep ocean engineering basin. To this end, the two-dimensional frequency domain boundary element method was applied to achieve an efficient analysis that reflects the geometric characteristics of the deep ocean engineering basin. The developed numerical method was validated through comparison with the analytical solution. Numerical analyses were conducted for the boundary value problem of the wavemaker according to various periods and the positions of the movable bottom. The numerical results were used to investigate the effect of the geometric characteristics of the deep ocean engineering basin on the transfer function of the wavemaker, and the effect of depth on wave generation was checked by changing the position of the movable bottom. To efficiently utilize the various results of the boundary element method, a meta-model, an approximate model of the transfer function of the wave maker, was developed using a thin plate spline interpolation model. The validity of the developed meta-model was confirmed through a comparison of the results of the model tests.

• Parasites, Hosts and Diseases
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• v.59 no.6
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• pp.615-623
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• 2021

Human sparganosis is a food-borne parasitic disease caused by the plerocercoids of Spirometra species. Clinical diagnosis of sparganosis is crucial for effective treatment, thus it is important to identify sensitive and specific antigens of plerocercoids. The aim of the current study was to identify and characterize the immunogenic proteins of Spirometra erinaceieuropaei plerocercoids that were recognized by patient sera. Crude soluble extract of the plerocercoids were separated using 2-dimensional gel electrophoresis coupled with immunoblot and mass spectrometry analysis. Based on immunoblotting patterns and mass spectrometry results, 8 antigenic proteins were identified from the plerocercoid. Among the proteins, cysteine protease protein might be developed as an antigen for diagnosis of sparganosis.

• The Journal of the Acoustical Society of Korea
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• v.40 no.6
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• pp.555-565
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• 2021

The goal of this study is to improve flow and noise performances of existing backward-curved blade centrifugal fan system used for circulating cold air in a refrigerator freezer by optimally designing airfoil shape. The unique characteristics of the system is to drive cold airflow with two volute tongues in combination with duct system in a back side of a refrigerator without scroll housing generally used in a typical centrifugal fan system. First, flow and noise performances of existing fan system were evaluated experimentally. A P-Q curve was obtained using a fan performance tester in the flow experiment, and noise spectrum was measured in an anechoic chamber in the noise experiment. Then, flow characteristics were numerically analyzed by solving the three-dimensional unsteady Navier-Stokes equations and noise analysis was performed by solving the Ffowcs Williams and Hawkins equation with input from the flow simulation results. The validity of numerical results was confirmed by comparing them with the measured ones. Based on the verified numerical method, blade inlet and outlet angles were optimized for maximum flow rate using the two-factor central composite design of the response surface method. Finally, the flow and noise performances of a prototype manufactured with the optimum design were experimentally evaluated, which showed the improvement in flow and noise performance.

• Journal of Korea Water Resources Association
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• v.54 no.11
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• pp.933-942
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• 2021

The surface image velocimetry was developed to measure river flow velocity safely and effectively in flood season. There are a couple of methods in the surface image velocimetry. Among them the spatio-temporal image velocimetry is in the spotlight, since it can estimate mean velocity for a period of time. For the spatio-temporal image velocimetry analyzes a series of images all at once, it can reduce analyzing time so much. It, however, has a little drawback to find out the main flow direction. If the direction of spatio-temporal image does not coincide to the main flow direction, it may cause singnificant error in velocity. The present study aims to propose a new method to find out the main flow direction by using a fast Fourier transform(FFT) to a spatio-temporal (image) volume, which were constructed by accumulating the river surface images along the time direction. The method consists of two steps; the first step for finding main flow direction in space image and the second step for calculating the velocity magnitude in main flow direction in spatio-temporal image. In the first step a time-accumulated image was made from the spatio-temporal volume along the time direction. We analyzed this time-accumulated image by using FFT and figured out the main flow direction from the transformed image. Then a spatio-temporal image in main flow direction was extracted from the spatio-temporal volume. Once again, the spatio-temporal image was analyzed by FFT and velocity magnitudes were calculated from the transformed image. The proposed method was applied to a series of artificial images for error analysis. It was shown that the proposed method could analyze two-dimensional flow field with fairly good accuracy.