• 한국발생생물학회지:발생과생식
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• 제21권1호
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• pp.71-78
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• 2017

Nesfatin-1/NUCB2 is known to take part in the control of the appetite and energy metabolism. Recently, many reports have shown nesfatin-1/NUCB2 expression and function in various organs. We previously demonstrated that nesfatin-1/NUCB2 expression level is higher in the pituitary gland compared to other organs and its expression is regulated by $17{\beta}-estradiol$ and progesterone secreted from the ovary. However, currently no data exist on the expression of nesfatin-1/NUCB2 and its regulation mechanism in the pituitary of male mouse. Therefore, we examined whether nesfatin-1/NUCB2 is expressed in the male mouse pituitary and if its expression is regulated by testosterone. As a result of PCR and western blotting, we found that a large amount of nesfatin-1/NUCB2 was expressed in the pituitary and hypothalamus. The NUCB2 mRNA expression level in the pituitary was decreased after castration, but not in the hypothalamus. In addition, its mRNA expression level in the pituitary was increased after testosterone treatment in the castrated mice, whereas, the expression level in the hypothalamus was significantly decreased after the treatment with testosterone. The in vitro experiment to elucidate the direct effect of testosterone on NUCB2 mRNA expression showed that NUCB2 mRNA expression was significantly decreased with testosterone in cultured hypothalamus tissue, but increased with testosterone in cultured pituitary gland. The present study demonstrated that nesfatin-1/NUCB2 was highly expressed in the male mouse pituitary and was regulated by testosterone. This data suggests that reproductive-endocrine regulation through hypothalamus-pituitary-testis axis may contribute to NUCB2 mRNA expression in the mouse hypothalamus and pituitary gland.

• 한국결정학회지
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• 제6권2호
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• pp.141-157
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• 1995

직경자동제어장치를 이용한 초크라스키법에 의해 대형 TeO2 단결정을 공기 중에서 성장시켰다. 온도구배를 가능한 한 적게 한 성장조건 하에서 단결정과 도가니의 직경비율을 60-70% 범위에서 양질의 단결정 성장이 가능하였다. 이 때 결정의 품질을 좌우하는 주요 요인은 인상 및 회전 속도였다. 무색 투명한 고품질 단결정을 육성하기 위한 인상속도는 1.2mm/hr 이하였고, 고액계면은 10-23 rpm 이하일 때 볼록하였으며, 25 rpm 이상일 때 오목하였다. 단결정의 성장은 {110} 방향의 종자결정을 사용하였다. 용융체 내의 백금 함량이 증가하면 조성적 과냉이 발생하여, 성장되는 결정 내에 기포가 포획되므로 성장된 단결정의 질이 저하된다. 적외선 측정결과 파수 2,000cm-1 이상에서 완전 투명하였고, 전위밀도를 측정 결과 직경자동제어를 이용한 경우 3×103/cm2 - 2×104/cm2로 양호하였으며 수동성장인 경우도 결정과 도가니의 직경비율이 40-45%의 범위에서는 매우 양호하였다. 또한 포유물 등 불순물에 혼입 원인에 대하여 논하였다.

• Restorative Dentistry and Endodontics
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• 제15권1호
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• pp.107-119
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• 1990

The purpose of this study was to evaluate the marginal adaptability of the amalgam restorations in applying the cavity varnish (Copalite$^{(R)}$) and dentin bonding agent (Scotchbond 2$^{(R)}$) under the scanning electron microscope. For this study, eighteen sound extracted human molars were selected. Class I cavities in 12 teeth and class V cavities in 6 teeth were prepared using an air turbine with No. 701 tungsten carbide bur and finished using a low speed handpiece with No. 557 fissure bur. The prepared specimens were then divided into three groups including 4 class I cavities and 2 class V cavities in each group and restored as follows ; Group I. All the prepared cavities were restored with amalgam only (Control). Group II. Two layers of Copalite$^{(R)}$ cavity varnish were applied to the cavities with a gentle stream of air after each application and cavities were restored with amalgam. Group III. The enamel cavity margins were etched with 37% phosphoric acid gel for 60 sec., rinsed for 30 sec. and dried. One layer of visible lightcured Scotchbond Dental Adhesive$^{(R)}$ was applied and immediately cured for 20 seconds with visible light-cure unit and cavities were restored with amalgam. All the specimens were cut at the neck of the teeth and the occlusal halves of specimens were sectioned buccolingually in the longitudinal axis centering the amalgam restorations, using the disk. The cut specimens were ground with sandpapers (400, 600, 800, 1000 grit), and cleaned for 5 minutes in the ultrasonic cleaner (Brason Co. U.S.A.). In the cut surfaces, the amalgam - tooth interfaces were examined under the scanning electron microscope (JSM, 35C type, JEOL). The obtained results were as follows ; 1. The amalgam-tooth interfaces were reduced more significantly in the Copalite$^{(R)}$ and Scotchbond 2$^{(R)}$ application group than in the control group. 2. In the class I cavities, the Scotchbond 2$^{(R)}$ application group showed the findings similar to the Copalite$^{(R)}$ application group in the cavity floor, and the marginal adaptability was better in the side wall than in the cavity floor. 3. In the class I cavities, the Scotchbond 2$^{(R)}$ application group showed better marginal adaptability in the occlusal margin than in the gingival margin. 4. The marginal adaptability was in the order of the Scothbond 2$^{(R)}$ application group, the Copalite$^{(R)}$ application group and the control group.

• 한국표면공학회:학술대회논문집
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• 한국표면공학회 1999년도 추계학술발표회 초록집
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• pp.15-15
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• 1999

In chip plating, several parameters must be taken into consideration. Current density, solution concentration, pH, solution temperature, components volume, chip and media ratio, barrel geometrical shape were most likely found to have an effect to the process yields. The 3 types of barrels utilized in chip plating industry are the conventional rotating barrel. vibrational barrel (vibarrel), and the centrifugal type. Conventional rotating barrel is a close type and is commonly used. The components inside the barrel are circulated by the barrel's rotation at a horizontal axis. Process yield has known to have higher thickness deviation. The vibrational barrel is an open type which offers a wide exposure to electrolyte resulting to a stable thickness deviation. It rotates in a vertical axis coupled with multi-vibration action to facilitate mixed up and easy transportation of components, The centrifugal barrel has its plated work centrifugally compacted against the cathode ring for superior electrical contact with simultaneous rotary motion. This experiment has determined the effect of barrel vibration intensity to the plating thickness distribution. The procedures carried out in the experiment involved the overall plating process., cleaning, rinse, Nickel plating, Tin-Lead plating. Plating time was adjusted to meet the required specification. All other parameters were maintained constant. Two trials were performed to confirm the consistency of the result. The thickness data of the experiment conducted showed that the average mean value obtained from higher vibrational intensity is nearer to the standard mean. The distribution curve shown has a narrower specification limits and it has a reduced variation around the target value, Generally, intensity control in vi-barrel facilitates mixed up and easy transportation of components, However, it is desirable to maintain an optimum vibration intensity to prevent solution intrusion into the chips' internal electrode. A cathodic reaction can occur in the interface of the external and internal electrode. $2HD{\;}+{\;}e{\;}{\rightarrow}20H{\;}+{\;}H_2$ Hydrogen can penetrate into the body and create pressure which can cause cracks. At high intensity, the chip's motion becomes stronger, its contact between each other is delayed and so plating action is being controlled. However, the strong impact created by its collision can damage the external electrode's structure thereby resulting to bad plating condition. 1 lot of chip was divided into two equal partion. Each portion was loaded to the same barrel one after the other. Nickel plating and tin-lead plating was performed in the same station. Portion A maintained the normal barrel vibration intensity and portion B vibration intensity was increased two steps higher. All other parameters, current, solution condition were maintained constant. Generally, plating method find procedures were carried out in a best way to maintained the best plating condition. After plating, samples were taken out from each portion. molded and polished. Plating thickness was investigated for both. To check consistency of results. 2nd trial was done now using different lot of another characteristics.

• 가정과삶의질연구
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• 제15권2호
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• pp.71-71
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• 1997

This study aims ai the extraction of what is universally to be taught in modern Korean Families and its scalization. That is, it attempts to provide the criterion by which we can determine what to teach adolescent in the family, not in society or school. For this purpose, this study firstly reviews the preceeding studies on the subject. As a result of the review, we postulate the hypothetical structure consisting of 11 domains. Secondary, we gather the parent's view on the topic by interviewing 496 parents with teenagers. On the basis of this study, we can construct the questionnaire(Likert scale; 5 point). After we conduct an extensive empirical research(346 parents) in order to generalize 195 items of the workedout questionnaire. We apply factor analysis(principal axis factoring, oblique (promax) rotation) in the verification of the validity. As the consequence, we select 66 items consisting, 10 factors, which explain 68% of common variance. We name the 10 educational factors extracted in the scale as follows ; The Sense of Value, Communal Society, Sex, Esteem for an ancestor & a traditional way of life, Parent-Child Relationship, the Culture life within the family, The Guide of Learning Way, Setting up the way of life, The control of one's life, Friendship. The reliability of the scale is the cronbach =0.91 which turns out to be satisfactory.

• 한국정밀공학회지
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• 제26권2호
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• pp.35-44
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• 2009

Long stroke Fast Tool Servo (LFTS) with maximum stroke of $432{\mu}m$ is designed, manufactured and tested for fabrication of optical free-form surfaces. The large amount of stroke in LFTS has been realized by utilizing the hinge and lever mechanisms which enable the displacement amplification ratio of 4.3. In this mechanism the peculiar shape was devised for maximizing the displacement of end tip in LFTS and special mechanical spring has been mounted to provide the sufficient preload to the piezoelectric actuator. Also, its longitudinal motion of tool tip can be measured by capacitive type displacement sensor and closed-loop controlled to overcome the nonlinear hysteresis. In order to verify the static and dynamic characteristics of designed LFTS, several features including step response, frequency response and cut-off frequency in closed-loop mode were experimentally examined. Also, basic machining result shows that the proposed LFTS is capable of generating the optical free-form surface as an additional axis in diamond turning machine.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.2175-2178
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• 2005

Selective Laser Sintering(SLS) method is one of Rapid Prototyping(RP) technologies. It has been used to fabricate desirable part to sinter powder and stack the fabricated layer. Since the sintering process occurs using infrared laser having high thermal energy, shrinkage and curling of the fabricated part occurs according to thermal distribution. Therefore, the fast scanning path generation is necessary to eliminate the factors of quality deterioration. In case of fabricating larger size parts, the unique scanning device and scanning path generation should be considered. In this paper, the development of SLS machines being capable of large size fabrication(800${\times}$1000${\times}$800 mm, W${\times}$D${\times}$H) will be addressed. The dual laser system and the unique scanning device have been designed and built, which employ CO2 lasers and dynamic 3-axis scanners. The developed system allows scanning a larger planar surface with the desired laser spot size. Also, to generate the fast scanning paths, adaptive path generation is needed with respect to the shape of each layer, and not simply x, y scanning, but the scanning of arbitrary direction should be enabled. To evaluate the suggested method, the complex part will be used for the experiment fabrication.

• 한국CDE학회논문집
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• 제19권2호
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• pp.157-168
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• 2014

In this paper, HSE (Health and Safety Environments) research with smart device and biometrics is conducted for the worker's HSE enhancement in the manufacturing shop floor. Today, various kinds of smart devices are popularized extensively. In addition, the wearable type devices are being introduced such as google glass very recently. Smart device of werable type is exptected to bring great opportunity out in terms of HSE functionality. Smart devices of phone or tablet type are being used for on-line work between control center and manufacturing shop floor by virtue of wireless communication. However, those devices are not appropriate for detecting of worker's physical senses such as temperature and pulse. In this paper, we developed a glass type smart device and required funictions for HSE enhancement with the investigation of biometrics technology. Also, required sensors are investigated for the detecting of temperature, pulse and noxious gasses. Smart device of glass type has advantages in that most senses of personnel are gathered around faces, and also it's possible to detect neutral axis of body because the wearing location is fixed. We expect that the proposing HSE product of glass type smart device could contribute the enhancement of the HSE of manufacturing shop floor.

• 구강회복응용과학지
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• 제19권2호
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• pp.125-137
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• 2003

The use of screw-retaind prosthesis on an osseointegrated implant is a popular treatment modality offering relative ease in the removal of the restoration. One of the complications associated with this modality is the loosening of the abutment and coping screws. Loosening of the screws results in patient dissatisfaction, frustration to the dentist and, if left untreated, component fracture. There are several factors which contribute to the loosening of implant components which can be controlled by the restorative dentist and lab technician. This article offers pratical solutions to minimize this clinical problem and describes the factors involved in maintaining a stable screw joint assembly. To avoid joint failure, adherence to specific clinical, as well as mechanical, parameters is critical. With respect to hardware, optimal tolerance and fit, minimal rotational play, best physical properties, a predictable interface, and optimal torque application are mandatory. In the clinical arena, optimal implant distribution; load in line with implant axis; optimal number, diameter, and length of implants; elimination of cantilevers; optimal prosthesis fit; and occlusal load control are equally important.

• 한국기계가공학회지
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• 제11권5호
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• pp.60-67
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• 2012

In the study, the effect grinding condition on the workpiece arithmetical average roughness(Ra) to 10 steps leading to cutting each section with the spindle rotational speed 8000rpm and feed rate 150mm/min of grinding in GC(green silicon carbide) grinding processing after heat treatment and non heat treatment of SCM415 material. Also the following conclusions were obtained analysis of stress distribution displacement and finite elements method(FEM) on assemble parts with 3+2 axis simultaneous control through grinding and gave a load 11kg on ATC arm both sides gave a load of 11kg. For the centerline average roughness(Ra) in the heat and non-heat treatment work pieces, which were appeared the most favorable in the fifth section were $0.511{\mu}m$ and $0.514{\mu}m$, that were shown in the near the straight line section was the smallest deformation of curve. In addition, the bad surface roughness appeared on the path is too long by changing angle, the more inclined depth of cut, because the chip discharging is not smoothly.