• Asian Pacific Journal of Cancer Prevention
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• 제16권6호
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• pp.2209-2213
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• 2015

DNA methylation of tumor suppressor gene promoters is the most frequent phenomenon leading to inactivation of function, consequently driving malignant cell transformation. Cyclin D2 is implicated in tumor suppression. In our study, we carried out the MSP assay to evaluation the methylation status at CpG islands in the cyclin D2 promoter in breast cancer cases from the Vietnamese population. The results showed that the frequency of methylation reached 62.1% (59 of 95 breast cancer tumors), but was low in non-cancer specimens at 10% (2 of 20 non-cancer specimens). Additionally, with an RR (relative risk) and OR (odd ratios) of 6.21 and 14.8, DNA hypermethylation of cyclin D2 increased the possibility of malignant transformation. Our results confirmed the cyclin D2 hypermethylation could be used as the potential biomarker which could be applied in prognosis and early diagnosis of Vietnamese breast cancer patients.

• 한국의류산업학회지
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• 제9권2호
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• pp.138-144
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• 2007

The purpose of this research was to compare the harmony of tone on tone coloration according to transformation of color area-ratio in shirt and necktie. The respondents were asked to evaluate 48 stimuli of the shirt and necktie with the coloration of the shirt/necktie, the necktie/shirt was separately compounded to be 4 tones such as vivid, light, dull, dark. The subjects were 288 female undergraduate students. The data was analyzed by using SPSS program. Analysis methods were ANOVA, LSD test and t-test. The results of each can be summerized as follows. As to the red, combination of v-lt made a difference in the harmony of coloration according to the transformation of color area-ratio. As to the blue, combination of v-lt, v-dk, lt-d made a difference in the harmony of coloration according to the transformation of color area-ratio. As to the purple, v-lt, v-d was evaluated as harmonized coloration regardless of area-ratio by both male and female students. As to the green, v-lt, lt-d was evaluated as harmonized coloration regardless of area-ratio by both male and female students.

• 센서학회지
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• 제28권3호
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• pp.182-186
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• 2019

When a camera is employed for 3D sensing, accurate camera calibration is vital as it is a prerequisite for the subsequent steps of the sensing process. Camera calibration is usually performed by complex mathematical modeling and geometric analysis. On the other contrary, data learning using an artificial neural network can establish a transformation relation between the 3D space and the 2D camera image without explicit camera modeling. However, a neural network requires a large amount of accurate data for its learning. A significantly large amount of time and work using a precise system setup is needed to collect extensive data accurately in practice. In this study, we propose a two-step neural calibration method that is effective when only a small amount of learning data is available. In the first step, the camera projection transformation matrix is determined using the limited available data. In the second step, the transformation matrix is used for generating a large amount of synthetic data, and the neural network is trained using the generated data. Results of simulation study have shown that the proposed method as valid and effective.

• 방송공학회논문지
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• 제16권4호
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• pp.584-595
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• 2011

최근 RGB 영상과 깊이맵이 동시에 제작되어 공급되고 있다. 깊이맵은 사용자의 용도에 따라 다양한 형태로 변환되어 입체영상 제작에 사용된다. 깊이맵을 활용하는 기법이 새로이 소개되고 있는데, 한 예로 의료 분야에서 2D 영상의 컬러를 변환하여 지각 깊이감을 개선하는 영상처리 기술에 대한 관심이 높아지고 있다. 본 논문에서는 기존의 컬러 변환을 통한 2D 영상의 지각 깊이감 개선을 입체영상에 적용하여, 3D 지각 깊이감을 동시에 향상시키는 방법을 제안한다. 이를 위해 대조 변환 및 배경 다크닝 방법을 제안하고, 실험을 통해 제안 방법이 상기 목적을 얻을 수 있는 것을 검증하였다. 주관적 실험에서는 입체감 향상 및 피로도 측정을 통해 제안 방법의 성능 및 단점을 제시하였다.

• 대한지리학회지
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• 제41권2호
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• pp.188-194
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• 2006

3차원 위상 자료는 응급상황 처리와 3차원 네트워크 분석 등의 3차원 공간분석에 필수적으로 요구된다. 이 연구에서는 현재까지의 3차원 위상 데이터 모델에 대해 살펴보고, 건물을 설계하기 위해 사용되는 2차원 CAD 도면 데이터로 부터 3차원 위상적 노드-관계 데이터를 추출하는 방법을 개발하였다. 이 방법은 중심축 변환과 위상적 노드-관계 알고리듬들을 이용한 두 단계로 이루어진다. 첫번째 단계는 중심축 변환 알고리듬을 이용하여 CAD 데이터에서 폴리곤이나 이중 선으로 표현되는 벽으로부터 그 중심선을 생성하여 벽의 골격을 추출하는 것이다. 두번째 단계는 추출된 벽의 골격 자료를 이용하여 방을 3차원 노드로하고 방들간의 연결을 관계로하는 위상적 노드-관계 구조를 생성하는 것이다. 따라서, 그러한 연결들은 노드들간의 이웃성 또는 연결성을 표현하게 된다. 결론적으로, 이러한 변환방법으로 미시적 수준의 개별 건물들의 내부구조를 표현하는 3차원 위상구조 데이터는 건물의 도면 작성에 자주 사용되는 CAD 데이터로 부터 쉽게 생성될 수 있을 것이다.

• The Journal of Advanced Prosthodontics
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• 제11권1호
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• pp.1-6
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• 2019

PURPOSE. The purpose of this in vitro study was to evaluate the effect of surface grinding and polishing procedures using high speed zirconia diamond burs with different grit sizes on the phase transformation and flexural strength of zirconia. MATERIALS AND METHODS. Forty disc shape specimens ($15{\times}1.25mm$) with a cylindrical projection in the center of each disc ($1{\times}3mm$) were fabricated with 3Y-TZP (Prettau, Zirkonzahn, Italy). The specimens were divided into 4 groups (n=10) according to the grinding and polishing procedures: Control group - grinding (coarse-grit diamond bur), Group 1 - grinding (coarse-grit diamond bur) + polishing, Group 2 - grinding (fine-grit diamond bur) + polishing, and Group 3 - grinding (fine grit diamond bur). Each specimen was analyzed by 3D-OM, XRD analysis, and biaxial flexural strength test. RESULTS. Based on the surface morphology by 3D-OM images, polished specimens showed smoother surface and lower roughness value (Ra). In the result of XRD analysis, partial phase transformation from tetragonal to monoclinic zirconia occurred in all groups. Control group, ground with a coarse grit diamond bur, showed more $t{\rightarrow}m$ phase transformation and lower flexural strength than Groups 1 and 2 significantly. CONCLUSION. The flexural strength in all specimens after grinding and polishing showed over 500 MPa, and those were clinically acceptable. However, grinding with a coarse grit diamond bur without polishing induced the phase transformation and low strength. Therefore, surface polishing is required for the occlusal adjustment using a high speed zirconia diamond bur to reduce the phase transformation and to prevent the decrease of flexural strength of zirconia.

• Nuclear Engineering and Technology
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• 제41권2호
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• pp.199-214
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• 2009

High burn-up transformation process in low temperature nuclear fuel oxides material was observed in the early sixties in LWR $UO_2$ fuels, but not studied in depth. Increasing progressively the fuel discharge burn-up in PWR power plants, this material transformation was again observed in 1985 and identified as an important process to be accounted for in the fuel simulations due to its expected consequence on fuel heat transfer and therefore on the fission gas release. Fission gas release was one of the major concerns in PWR fuels, mainly during transient or accidents events. The behaviour of such a material in case of rod failure was also an important aspect to analyse. Therefore several national and international programs were launched during the last 25 years to understand the mechanisms leading to the high burn-up structure formation and to evaluate the physical properties of the final material. A large observations database has been acquired, using the more sophisticated techniques available in hot cells. This large database is discussed in this paper, providing basis to build an engineering-model, which is based on phenomenological description data and information accumulated. In addition this paper has the ambition to construct the best logical model to understand restructuring.

• Journal of Plant Biotechnology
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• 제29권2호
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• pp.85-92
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• 2002

Agrobacterium을 이용한 벼의 효율적인 형질전환을 위하여 몇 가지 형질전환 조건을 조사하였다. 그리고 조사된 최적의 형질전환 방법을 이용하여 내한성에 관련된 GPAT 유전자를 식물에 도입하였다. 형질전환 조건은 GUS 발현을 통하여 조사되었다. 본 실험에서는 벼 (Oryza sativa L. cv. Dongjin)의 성숙 종자 유래 캘러스를 3일간 전배양한 후 Agrobacterium을 접종하였다. 접종이 끝난 캘러스는 50mg/L CaCl$_2$, 30mg/L acetosyringone, 2 mg/L 2,4-D, 120 mg/L betaine이 첨가된 공동배양 배지 위에서 암조건으로 10일간 공동배양하여 높은 GUS 발현을 관찰할 수 있었다. 이와 같은 방법으로 GPAT 유전자를 식물에 도입한 결과 54%의 높은 형질전환율을 나타내었다. 형질전환 식물체를 southern 분석한 결과 wild type 식물체에서는 GPAT 유전자가 검출되지 않았으나, 형질전환 식물체에서는 GPAT 유전자가 검출되었다. 또한 GPAT 유전자로 형질전환된 5 계통의 T1 세대에서 hygromycin에 대한 저항성과 감수성의 유전비율이 3 : 1로 분리되었다. 따라서 본 실험의 결과에서 검토된 고빈도의 형질전환 시스템은 단자엽식물의 형질전환에 있어서 모델계로 이용될 수 있으리라 기대된다.

• 전자공학회논문지S
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• 제34S권2호
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• pp.52-62
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• 1997

To reconstruct the complete 3-D shape of an object, seveal range images form different viewpoints should be merged into a single model. The process of extraction of the transformation parameters between multiple range views is calle dregistration. In this paper, we propose a new algorithm to find the transformation parameters between multiple range views. Th eproposed algorithm consists of two step: initial estimation and iteratively update the transformation. To guess the initial transformation, we modify the principal axes by considering the projection effect, due to the difference fo viewpoints. Then, the following process is iterated: in order to extract the exact transformation parameters between the range views: For every point of the common region, find the nearest point among the neighborhood of the current corresponding point whose correspondency is defined by the reverse calibration of the range finder. Then, update the transformation to satisfy the new correspondencies. In order to evaluate the performance the proposed registration algorithm, some experiments are performed on real range data, acquired by space encoding range finder. The experimental results show that the proposed initial estimation accelerate the following iterative registration step.

• Journal of applied mathematics & informatics
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• 제27권3_4호
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• pp.757-762
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• 2009

In allelic model $X\;=\;(x_1,\;x_2,\;{\cdots},\;x_d)$, $$M_f(t)\;=\;f(p(t))\;-\;{\int}^t_0\;Lf(p(t))ds$$ is a P-martingale for diffusion operator L under the certain conditions. We can also obtain a new diffusion operator $L^*$ for diffusion coefficient and we prove that unique solution for $L^*$-martingale problem exists. In this note, we define new symmetric preserving transformation. Uniqueness for martingale problem and symmetric property will be proved.