• 제목/요약/키워드: 2-Chloro quinoline-4-carboxamides

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Design, Synthesis and Antibacterial Activity Studies of Novel Quinoline Carboxamide Derivatives

  • Shivaraj, Yellappa;Naveen, Malenahalli H.;Vijayakumar, Giriyapura R.;Kumar, Doyijode B. Aruna
    • 대한화학회지
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    • 제57권2호
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    • pp.241-245
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    • 2013
  • A series of novel quinoline-6-carboxamides and 2-chloroquinoline-4-carboxamides were synthesized by the reaction of their analogous carboxylic acids with various amine derivatives in the presence of base TEA and protecting agent BOP at room temperature. Synthesized compounds were confirmed by spectral characterization viz IR, $^1H$-NMR, and MS. Antibacterial activity carried out against Escherichia coli and Staphyllococcus aureus indicated that the synthesized compounds were active against these microorganisms.