• Title/Summary/Keyword: 2-Acylpyridazin-3(2H)-one

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Rapid and Ecofriendly Esterification of Alcohols with 2-Acylpyridazinones

  • Kim, Bo Ram;Sung, Gi Hyeon;Ryu, Ki Eun;Kim, Jeum-Jong;Yoon, Yong-Jin
    • Bulletin of the Korean Chemical Society
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    • v.34 no.11
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    • pp.3410-3414
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    • 2013
  • Atom-economical esterification is of great importance in green chemistry. In this work, we demonstrated the catalyst and additive free esterification of alcohols by their reaction with 2-acyl-4,5-dichloropyridazin-3(2H)-ones without solvent at $100^{\circ}C$. Aliphatic and aromatic alcohols were converted into the corresponding esters in good to excellent yields. It is noteworthy that the reaction is solvent-free, atom-economic, easy-workup, and rapid and that the process is inexpensive.