• Title/Summary/Keyword: 2차 방사선

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GARRE'S OSTEOMYELITIS IN CHILDREN (소아에서의 Garre 골수염)

  • Woo, Se-Eun;Kim, Young-Jin;Kim, Hyun-Jung;Nam, Soon-Hyeun
    • Journal of the korean academy of Pediatric Dentistry
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    • v.38 no.4
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    • pp.413-420
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    • 2011
  • Garre's osteomyelitis is associated with bacterial infection and bone necrosis resulting from obstruction of blood supply. The most common cause for Garre's osteomyelitis is odontogenic infection that originates from periodontal tissue or dental pulp. Subperiosteal abscess may also cause Garre's osteomyelitis in the progress of the infection. Mandible is more often affected than maxilla, most commonly in the permanent first molar region of mandible. Clinically, it results in a hard swelling over the jaw, producing facial asymmetry. Meanwhile, radiograph shows a characteristic feature of irregular pulpal cavity, showing new periosteal proliferation located in successive layers to the condensed cortical bone on stimulated site. The treatment method for Garre's osteomyelitis are removal of the infection source, root canal treatment, antibiotic medication, and incision and drainage. This report presents a case of Garre's osteomyelitis under 15 years old. The patient was successfully treated by antibiotic medication accompanied with root canal treatment. Since the symptom of pediatric patients is less severe than adult, careful diagnosis with history taking and clinical examination is necessary. Furthermore long-term follow-up examination is needed to prevent recurrence even after the symptom disapears.

The Effect of Thin Teflon on TLD Response for in vivo Dosimetry of Radiotherapy (생체 내 흡수선량 측정을 위한, 얇은 테프론의 TLD 반응감도에 대한 효과성)

  • Kim, Sookil;Yum, Ha-Young;Jeong, Tae-Sig;Moon, Chang-Woo
    • Progress in Medical Physics
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    • v.14 no.2
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    • pp.74-80
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    • 2003
  • The purpose of this study was to evaluate the performance of the teflon encapsulated TLD rod, which may be used in nuclear medicine for the direct in vivo measurements of radiation dose. We analyzed the influence of teflon encapsulation for measuring absorbed dose. An experiment was carried out to evaluate and observe the response of a LiF TLD-100 rod in a thin-wall teflon capsule at different depths in a solid phantom. An adult anthropomorphic phantom was used to measure the absorbed dose using thin teflon encapsulated TLD. The measurements of PDD-, and TMR in solid phantom and athe bsorbed dose in humanoid phantom performed with normal TLD were compared with values obtained by teflon encapsulated TLD. It was demonstrated that the difference of TL response of LiF in phantom with and without teflon thin-wall capsule was less than 3% under the same conditions beyond the build-up region. However, significant differences were observed near the phantom surface because of the build-up effect caused by the thin-wall thickness of the teflon capsule. Thus, our study showed that the contribution of teflon thin-wall capsule to TLD response for the megavoltage photon beams was negligible and that it did not significantly effect dose measurement. The teflon encapsulated TLD described in this work has been proven to be appropriate for in vivo dosimetry in therapeutic environments.

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Intra-articular Corticosteroid Treatment of Biceps Tenosynovitis in a Dog (개에서 두갈래근 힘줄 윤활막염의 관절강 내 코티코스테로이드 치료 1예)

  • Lee, Jae-Yeon;Jee, Hyun-Chul;Lee, Ki-Ja;Park, Seong-Jun;Choi, Ho-Jung;Lee, Young-Won;Kim, Myung-Cheol;Jeong, Seong-Mok
    • Journal of Veterinary Clinics
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    • v.24 no.1
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    • pp.32-34
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    • 2007
  • A 3-year-old, 35kg, neutered male Borzoi was admitted with a history of intermittent weight-bearing left forelimb lameness. Physical examination revealed pain response on left bicipital tendon during palpation of the tendon and shoulder flexion and extension. Radiographic findings of the left shoulder joint included intertubercular grove osteophytes and periarticular changes. Arthrograms revealed a roughened and irregular appearance to the biceps tendon. Synovial fluid analysis is consistent with degenerated joint disease. It was diagnosed as biceps tenosynovitis on the basis of history, physical examination, radiography and arthrograms. The dog was treated with medical management. Medical treatment included an aseptic intra-articular injection of 40mg methylprednisolone acetate in the left shoulder and strict exercise restriction. Three weeks later, the dog responded well to glucocorticoid therapy.

Distribution of Radioactivities of $^{226,228}Ra,\;^{137}Cs$ and $^{40}K$ in Soil in Busan Area (부산지역 토양의 $^{226,228}Ra,\;^{137}Cs$$^{40}K$ 방사능 분포)

  • Seo, Bum-Kyoung;Sung, Jung-Wook;Kim, Hyun-Duck;Lee, Dae-Won
    • Journal of Radiation Protection and Research
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    • v.26 no.4
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    • pp.441-445
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    • 2001
  • In this work we investigated distribution of the natural and artificial radioactive nuclides and level of the regional background in soil in Busan. For 45 points, the environmental radioactivity concentration of Busan surface soil is $14.38{\sim}57.03\;(mean\;:\;33.95)\;Bq{\cdot}kg^{-1}$ for $^{226}Ra,\;2.41{\sim}86.58\;(mean\;:\;51.08)\;Bq{\cdot}kg^{-1}$ for $^{228}Ra,\;223.64{\sim}1332.30\;(mean\;668.51)\;Bq{\cdot}kg^{-1}$ for $^{40}K$ and $<0.33{\sim}33.37\;(mean:13.74) Bq{\cdot}kg^{-1}$ for $^{137}Cs$. Also, in order to investigate vertical distribution for radioactivity, we examined radioactive concentration with mountain height. But there was no correlation between radiaoactivity distribution and mountain height. The $^{226}Ra/^{228}Ra$ and $^{226}Ra/^{40}K$ concentration ratios were $0.68{\pm}19 %$ and $0.06{\pm}34%$, respectively.

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Diagnosis and Treatment of Gastric MALT Lymphoma (위 MALT 림프종의 진단 및 치료에 대한 고찰)

  • Tae Ho Kim
    • Journal of Digestive Cancer Research
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    • v.3 no.2
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    • pp.82-88
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    • 2015
  • Gastric lymphoma comprises 1-6% of all gastric malignant neoplasms and among them 50% is gastric MALT lymphoma. The 60-70% of MALT lymphomas is diagnosed at early, localized diseased state. Gastric MALT lymphoma is assumed that it progress slowly with indolent course. It presents nonspecific symptoms such as epigastric pain, dyspepsia, nausea and vomiting. It is rarely associated with serious complication such as gastrointestinal bleeding or perforation. The definite diagnosis of gastric MALT lymphoma should be made with histopathologically. Wotherspoon score is used to differential diagnosis with Helicobacter pylori associated gastric inflammatory change. Gastric MALT lymphoma is associated with Helicobacter pylori infection with supported by epidemiologic and histopathologic studies. Gastric MALT lymphoma is characterized with genetic aberrations such as trisomy 3, trisomy 18, chromosomal translocations t(11;18), t(1;14), t(14;18), t(3;14). Appropriate clinical staging is essential to determine the optimal treatment strategy for gastric MALT lymphoma. Lugano International Conference classification has been applied widely. Helicobacter pylori eradication is used as the first line treatment for gastric MALT lymphoma independent of the stage. The complete remission has been achieved in 60-90% of the stage I/II1 patients with Helicobacter pylori eradication only. The treatment options for the patients with refractory to eradication are radiotherapy, chemotherapy and/or immunotherapy with the complete remission rate of 75% to 100%. The incidence of gastric MALT lymphoma can be expected to down by virtue of the decrease of Helicobacter pylori infection rate. Further basic and clinical research is necessary to advance in determine the pathogenesis and management.

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Studies on Degradation of Nucleic acid and Related Compounds by Microbial Enzymes (미생물 효소에 의한 핵산 및 그의 관련물질의 분해에 관한 연구)

  • Kim, Sang-Soon
    • Applied Biological Chemistry
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    • v.13 no.2
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    • pp.111-129
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    • 1970
  • As a series of studies on the nucleic acids and their related substances 210 samples were collected from 76 places such as farm soil, compost of heap, nuruk and meju to obtain microbial strains which produce 5'-phosphodiesterase. From these samples total of 758 strains were isolated by the use of dilution pour plate method. For all isolated strains primary screening of the productivity of RNA depolymerase was performed and useful strains with regard to 5'-phosphodiesterase productivities were identified. For these useful strains optimum condition, the effect of various compounds on the activity of 5'-phosphodiesterase, and the optimum condition for enzyme reaction were discussed. The quantitative of 5'-mononucleotides produced by the action of 5'-phosphodiesterase was performed using anion-exchange column chromatography and their identified was done by paper chromatography, thinlayer chromatography, ultra violet spectrophotometry, and characteristic color reaction using carbazole and schiff's reagent. (1) Penicillium citreo-viride PO 2-11 and Streptomyces aureus SOA 4-21 from soil were identified as a potent 5'-phosphodiesterase producing strains. (2) Optimum culture conditions for Penicillium citreo-viride PO 2-11 strain isolated were found to be pH 5.0 and $30^{\circ}C$, and the optimum conditions for enzyme action of 5'-phosphodiesterase were pH 4.2 and $60^{\circ}C$. Best carbon source for the production of 5'-phosphodiesterase was found to be sucrose and ammonium nitrate for nitrogen source. Addition of 0.01% corn steep liquor or yeast extract exhibited 20% increase in the amount of 5'-phosphodiesterase production compared to the control. 5'-phosphodiesterase produced by this strain was activated by $Mg^{++},\;Ca^{++},\;Zn^{++},\;Mn^{++}$ and was inhibited by EDTA, citrate, $Cu^{++},\;CO^{++}$. 5'-phosphodiesterase produced 5'-mononucleotide from RNA at a rate of 65.81%, and among the 5'-mononucleotides accumulated 5'-GMP only was found to have flavorous and the strain was also found lack of 5'-AMP deaminase. Productivity of flavorous 5'-GMP was found to be 186.7mg per gram of RNA. (3) Optimum culture canditions for the isolated Streptomyces aureus SOA 4-21 strain were pH 7.0 and $28^{\circ}C$, and the optimum conditions for the action of 5'-phosphodiesterase were pH 7.3 and $50^{\circ}C$. The best carbon source for 5'-phosphodiesterase production was found to be glucose and that of nitrogen was asparagine. Addition of 0.01% yeast extract exhibited increased productivity of 5'-phosphodiesterase by 40% compared to the non-added control. 5'-phosphodiesterase produced by this strain was activated by $Ca^{++},\;Zn^{++},\;Mn^{++}$ and was inhibited by citrate, EDTA, $Cu^{++}$. It was also found that the strain produce 5'-AMP deaminase in addition to 5'-phosphodiesterase. For this reason although decomposition rate was 63.58% the accumulation of 5'-AMP, 5'-CMP, 5'-GMP and 5'-UMP occurred by the breakdown of RNA. In the course of these reaction 5'-AMP deaminase converted 60% of 5'-AMP thus produced into 5'-IMP and flavorous 5'-mono nucleotide production was significantly increased by this strain over the above mentioned one. Production rates were found to be 171.8mg per grain of RNA for 5'-IMP and 148.2mg per gram of RNA for 5'-GMP, respectively.

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Evaluation of Dosimetric Characteristics of Reproducibility, Linearity and Dose Dependence of Optically Stimulated Luminescence Dosimeters in Co-60 Gamma-rays (Co-60 감마선을 이용한 광자극발광선량계의 재현성, 선형성, 선량의존성에 대한 특성평가)

  • Han, Su Chul;Choi, Sang Hyoun;Park, Seungwoo;Kim, Chul Hang;Jung, Haijo;Kim, Mi-Sook;Yoo, Hyung Jun;Kim, Chan Hyeong;Ji, Young Hoon;Yi, Chul Young;Kim, Kum Bae
    • Progress in Medical Physics
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    • v.25 no.1
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    • pp.31-36
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    • 2014
  • We aimed to evaluate the dosimetric characteristics of reproducibility, linearity and dose dependence of optical stimulated luminance dosimeter (OSLD) in the Co-60 Gamma-rays and to analyze with a precedent study in field of the diagnostic radiography and radiotherapy. The reproducibility was 0.76% of the coefficient of variation, the homogeneity was within 1.5% of the coefficient of variation and OSLD had supra-linear response more than 3 Gy. So the correlation between dose and count was fitted by quadratic function. The count depletion by repeated reading was 0.04% per reading regardless of the irradiated dose. And the half time of decay curve according to the irradiated dose was 0.68 min. with 1 Gy, 1.04 min. with 5 Gy, and 1.10 min. with 10 Gy, respectively. In case of annealing for 30 min, the removal rate was 88% with 1 Gy, 90% with 5 Gy, and 92% with 10 Gy, respectively and 99% in case of annealing time for 4 hour. It is feasible to use OSLDs for dose evaluation in Co-60 Gamma-rays when considering the uncertainty on the procedure according to the irradiated dose.

Comparison of Center Error or X-ray Field and Light Field Size of Diagnostic Digital X-ray Unit according to the Hospital Grade (병원 등급에 따른 X선조사야와 광조사야 간의 면적 및 중심점 오차 비교)

  • Lee, Won-Jeong;Song, Gyu-Ri;Shin, Hyun-yi
    • Journal of the Korean Society of Radiology
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    • v.14 no.3
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    • pp.245-252
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    • 2020
  • The purpose of this study was intended to recognize the importance of quality control (QC) in order to reduce exposure and improve image quality by comparing the center-point (CP) of according to hospital grade and the difference between X-ray field (XF) and light field (LF) in diagnostic digital X-ray devices. XF and LF size, CP were measured in 12 digital X-ray devices at 10 hospitals located in 00 metropolitan cities. Phantom was made in different width respectively, using 0.8 mm wire after attaching to the standardized graph paper on transparent plastic plate and marked as cross wire in the center of the phantom. After placing the phantom on the table of the digital X-ray device, the images were obtained by shooting it vertically each field of survey. All images were acquired under the same conditions of exposure at distance of 100cm between the focus-detector. XF and LF size, CP error were measured using the picture archiving communication system. data were expressed as mean with standard error and then analyzed using SPSS ver. 22.0. The difference in field between the XF and LF size was the smallest in clinic, followed by university hospitals, hospitals and general hospitals. Based on the university hospitals with the least CP error, there was a statistically significant difference in CP error between university hospitals and clinics (p=0.024). Group less than 36-month after QC had fewer statistical errors than 36-month group (0.26 vs. 0.88, p=0.036). The difference between the XF and LF size was the lowest in clinic and CP error was the lowest in university hospital. Moreover, hospitals with short period of time after QC have fewer CP error and it means that introduction of timely QC according to the QC items is essential.

Comparison of mandibular anterior alveolar bone thickness in different facial skeletal types (성인에서의 수평적, 수직적 안면 골격 형태에 따른 하악 전치부 치조골 두께의 비교)

  • Kim, Yoon-Soo;Cha, Jung-Yul;Yu, Hyung-Seog;Hwang, Chung-Ju
    • The korean journal of orthodontics
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    • v.40 no.5
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    • pp.314-324
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    • 2010
  • Objective: The purpose of this study was to determine differences of mandibular anterior alveolar bone thickness and symphysial cross sectional area in 9 different horizontal and vertical facial types. Methods: By using the initial cephalometric radiographs of 270 adult patients (male 135, female 135), the authors measured the buccolingual thickness of anterior alveolar bone on the basis of the root axis and symphysial cross sectional distance. Results: The high angle group showed significantly thinner buccolingual alveolar bone width except for the CEJ area and lingual alveolar bone width ($p$ < 0.05). The low angle group and Class I, II average group showed similar or significantly thicker alveolar bone width than the Class I average group ($p$ < 0.05). The Class III average group showed significantly thinner buccolingual and lingual alveolar bone width than Class I and II average groups ($p$ < 0.05). The Class III high angle group showed minimal alveolar bone width in all facial skeletal types. No significant difference was found in the symphysial cross sectional area of the different vertical facial skeletal types ($p$ > 0.05). Conclusions: The results of this study found that Class III high angle patients have thinner mandibular anterior alveolar bone thickness; therefore, more attention will be needed to determine the incisor position during orthodontic treatment for this group of patients.

The Effect of the Axial Plane on Measurement of Available Bone Height for Dental Implant in Computed Tomography of the Mandible (하악의 전산화 단층사진에서 횡단면이 임플랜트를 위한 가용골 높이의 결정에 미치는 영향)

  • Jhin, Min-Ju
    • Journal of Periodontal and Implant Science
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    • v.32 no.2
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    • pp.379-388
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    • 2002
  • For the success of dental implant, accurate radiographic evaluation is prerequisite for planning the location of the osseointegrated implants and avoiding injury to vital structures. CT/MPR(computed tomography/multiplanar reformation) shows improved visualization of inferior alveolar canal. In order to obtain cross-sectional images parallel to the teeth, the occlusal plane is used to orientate for the axial plane. If the direction of axial plane is not parallel to the occlusal plane, the reformatted cross-sectional scans will be oblique to the planned fixture direction and will not show the actual dimension of the planned fixture's location. If the available bone height which measured in the cross-sectional view is much greater than the actual available bone height, penetration of canal may occur. The aim of this study is to assess the effect of the axial plane to measurement of available bone height for dental implant in computed tomography of the mandible. 40 patients who had made radiographic stents and had taken CT were selected. The sites that were included in the study were 45 molar regions. In the central panoramic scan, the length from alveolar crest to superior border of inferior alveolar canal(available bone height, ABH) was measured in direction of reformatted cross-sectional plane(uncorrected ABH). Then, length from alveolar crest to superior border of canal was measured in direction of stent(corrected ABH). The angle between uncorrected ABH and corrected ABH was measured. From each ABH, available fixture length was decided by $Br{{\aa}}nemark$ system. The results were following ; the difference between two ABHs was statistically significant in both first and second molar(p< 0.01). The percentage of difference more than 1 mm was 8.7% in first molar and 15.5% in second molar. The percentage of difference more than 2 mm was 2.0% in first molar and 6.6% in second molar. The maximum value of difference was 2.5 mm in first molar and 2.2 mm in second molar. The correlations between difference of 2 ABHs and angle was positive correlations in both first and second molar. The correlation coefficient was 0.534 in first molar and 0.728 in second molar. The second molar has a stronger positive correlation. The percentage of disagreement between 2 fixture lengths from two ABHs was 24.4% in first molar and 28.9% in second molar.