• Clinical and Experimental Pediatrics
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• v.51 no.5
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• pp.506-511
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• 2008

Purpose : The results of pulmonary function test (PFT) in children are variable according to the patient's cooperation and comprehensiveness. This study has intended to figure out the effectiveness of pre-education and training with balloons on PFT in children. Methods : One hundred six children mean aged $9.35{\pm}2.92\;years$ were tested. All participants performed PFT twice in 30 minutes intervals. First PFT were performed after usual instruction and second PFT were performed according to randomly classified grouping; Group 1 : repeat PFT after training with balloons, Group 2 : repeat PFT after training and education, both, Group 3 : repeat PFT after education about objects and necessities of pulmonary function test, Group 4 : repeat PFT without any education and training. Results : There were no difference statistically on the results of percent of predicted $FEV_1$, $FEV_1/FVC$, $FEF_{25-75%}$ and PEFR in Group 1, 2 and 4 patients. In some cases, the average is decreased with repeated PFT. At the case of repeated PFT after education, the average of percent of predicted $FEV_1$, $FEV_1/FVC$, $FEF_{25-75%}$ and PEFR is increased. There was statistically significant difference on the value of $FEV_1$, $FEF_{25-75%}$ and PEFR between first and second PFT in Group 3. Conclusion : Training with balloons before PFT causes fatigueness and lowers concentration. Understanding of PFT makes results better than training. Therefore, enough explanation and education about PFT before examination is most effective for appropriate PFT in children.

• Clinical and Experimental Pediatrics
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• v.45 no.2
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• pp.214-222
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• 2002

Purpose : The aim of this study was to evaluate myocardial injury in children treated with adriamycin by echocardiography, which is non-invasive and safe measurement for children. Methods : Left ventricular dimensions, wall stress, and contractile function were determined by echocardiographic methods in 17 patient recepients with adriamycin chemotherapy at rest(group 1) and during stress(group 2). Twenty age-matched normal subjects were established as control group. Results : End-diastolic dimension was decreased in both groups(group 1; $92{\pm}7%$ of normal, group 2; $87{\pm}8%$ of normal, P<0.05). Left ventricular end diastolic volume and wall mass were also decreased in both groups(group 1; $96{\pm}12mL/m^2$ and $145{\pm}18g/m^2$, group 2; $87{\pm}8mL/m^2$ and $137{\pm}16g/m^2$, respectively, P<0.05 and P<0.05) and group 2 showed lower values than group 1. Meridional end systolic stress(ESSm) was increased in both groups but there was no significant difference between the two groups(group 1; $52.6{\pm}6.2g/cm^2$, group 2; $63.5{\pm}8.5g/cm^2$, P<0.05, normal value $45.7{\pm}3.5g/cm^2$). The load-independent relation of rate-corrected circumferential fiber shortening velocity(Vcfc) to ESSm has a significant abnormal change in 7 out of 17(41%) in group 1 and 12 out of 17(71%) in group 2. Conclusion : The load-dependent systolic index, such as fractional shortening, may fail to show abnormality because of the compensatory changes in preload and afterload which can mask the impaired contractility. Therefore, systolic performance also should be monitored by a load-indepedent contractility index such as slope value of the end-systolic pressure-dimension relation and the position of the left ventricular stress-fiber shortening velocity after exercise.

• Journal of Food Hygiene and Safety
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• v.27 no.1
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• pp.42-49
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• 2012

This study was carried out to investigate the toxicity of food Red No.2 in the Sprague-Dawley (SD) female rat for 4 weeks. SD rats were orally administered for 28 days, with dosage of 500, 1,000, 2,000 mg/kg/day. Animals treated with food Red No.2 did not cause any death and show any clinical signs. They did not show any significant changes of body weight, feed uptake and water consumption. There were not significantly different from the control group in urinalysis, hematological, serum biochemical value and histopathological examination. In conclusion, 4 weeks of the repetitive oral medication of food Red No.2 has resulted no alteration of toxicity according to the test materials in the group of female rats with injection of 2,000 mg/kg. Therefore, food Red No.2 was not indicated to have any toxic effect in the SD rats, when it was orally administered below the dosage 2,000 mg/kg/day for 4 weeks.

• Pediatric Infection and Vaccine
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• v.14 no.2
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• pp.129-135
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• 2007

Purpose : Kikuchi disease is a subacute necrotizing lymphadenitis characterized by fever, cervical lymphadenopathy and benign self-limiting course in young women especially, but rare in children. Their etiopathology is still unknown, but involved viruses and autoimmune mechanism were proposed. We investigated the clinical and laboratory characteristics of Kikuchi disease in children. Methods : Five patients were diagnosed of Kikuchi disease from January 2001 to June 2006 in Kyunghee University Hospital. We reviewed their medical records retrospectively and analyzed clinical and laboratory findings. Results : The mean age of 5 patients (male to female ratio; 2:3) was 9 yr 9 mon(range: 8 yr 2 mon-12 yr 6 mon). The chief complaints were sustained fever and cervical lymph node that was unilateral, tender and swollen. All patients were treated with antibiotics before diagnosis was made, and rash developed in 2 patients. One patient showed necrotic change in ultrasound with which we suspected Kikuchi disease. Three patients were examined by CT scan additionally. The interval between admission and cervical lymph node excisional biopsy ranged from 6 days to 15 days, and mean period was 9.6 days. All pathological findings were compatible to necrotizing lymphandenitis. Conclusion : Unnecessary laboratory and imaging studies, and treatment with antibiotics tend to be done before making diagnosis, and that caused prolonged hospitalization. Therefore we studied the clinical and laboratory characteristics of Kikuchi disease in children.

• Science of Emotion and Sensibility
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• v.17 no.1
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• pp.3-12
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• 2014

Quick and accurate learning of diverse electronic products has become an important daily task. In particular, software occupies core status in the control and operation of the products. This research tested the effects of learning method, schedule, and task difficulty in the learning of software. Using 2 (learning method: experiential vs. verbal) ${\times}$ 2 (learning schedule: spaced vs. massed) ${\times}$ 2 (difficulty: easy vs. difficult) between-subjects design, Experiment 1 tested participants' learning of file control using Windows Movie Maker. There was no effect of learning schedule on task completion time, but participants in experiential learning were faster in the completion of evaluation task compared with those in verbal learning condition. Importantly, as task difficulty increases participants in verbal condition showed markedly lower performance than those in experiential condition, which suggests that experiential learning is more effective with more difficult learning task. That is, in case of learning simple operation of software verbal learning using linguistic manual or instruction could be sufficient; on the other hand in case of learning complex operation learning from experience or tutorial mode would be more effective. Additional studies which manipulated task difficulty (Expt. 2) and inter-trial learning interval (Expt. 3) did not produce meaningful results.

• Geophysics and Geophysical Exploration
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• v.13 no.4
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• pp.407-415
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• 2010

MT soundings were carried out in 2008, in northern Victoria, Australia, as a continuing collaboration research of 2007 between Republic of Korea, Australia, and Japan. The main purpose of this research is to investigate electrical conductivity structure and thus help understanding of tectonic structure in central Victoria, which is believed to be closely linked to mineralization and magmatic processes of this region. The survey area is located in western Lachlan Fold Belts, which is the part of Tasman Fold Belts in southeastern Australia. An MT profile of 2008 is almost parallel to the one of 2007 and approximately 50 km away. The 2D inversion result of MT data also shows that the position of conductivity discontinuity near surface are well matched with the positions of major faults, such as Avoca Fault, which is the structural boundary between Stawell and Bendigo Zones, and Heathcote Fault Zone, which marks the boundary between Bendigo and Melbourne Zones. It is also confirmed from resistivity image that internal faults in Bendigo Zone are in listric form, which is implied to be formed by structural shortening during compressional orogenic activity in Silurian.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.49 no.2
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• pp.47-55
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• 2012

A discrete-time(DT) filter with high-order temporal moving average(TMA) using actively-weighted charge sampling is proposed in this paper. To obtain different weight of sampled charge, the variable transconductance OTA is used prior to charge sampler, and the ratio of charge can be effectively weighted by switching the control transistors in the OTA. As a result, high-order TMA operation can be possible by actively-weighted charge sampling. In addition, the transconductance generated by the OTA is relatively accurate and stable by using the size ratio of the control transistors. The high-order TMA filter has small size, increased voltage gain, and low parasitic effects due to the small amount of switches and sampling capacitors. It is implemented in the TSMC $0.18-{\mu}m$ CMOS process by TMA-$2^2$. The simulated voltage gain is about 16.7 dB, and P1dB and IIP3 are -32.5 dBm and -23.7 dBm, respectively. DC current consumption is about 9.7 mA.

• Journal of the Korean Geotechnical Society
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• v.31 no.1
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• pp.5-14
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• 2015

Seabed may undergo large excess pore water pressure in the case of long duration of high wave loading. This excess pore water pressure may reduce effective stress and, consequently, the seabed may liquefy. Thus, it is necessary to develop a numerical technique which can precisely evaluate the dynamic response of seabed due to wave action. In this study, a new numerical technique named mixed model (2D NIT & FLIP models) was proposed. The dynamic wave pressure and water flow velocity acting on the boundary between seabed and the wave field was estimated using 2D-NIT model. This result was used as input data in FLIP program for investigation of dynamic response of seabed. To secure the reliability of the mixed model, the numerical analysis results of the mixed model were compared with Yamamoto's solution and Chang's experiment results. The comparison results indicated that there were some differences between them, but the general trend of the effective stress increment and the excess pore water pressure along the depth of seabed was similar to each other. Thus, this study clearly supports the plausibility of the numerical analysis of the mixed model.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.12
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• pp.8879-8888
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• 2015

When the disaster like earthquake in urban area occur, due to the collapse accidents for subway, tunnel space with buildings or underground area, enormous property and human damage are happened. Specially, since it is difficult to identify survived status of humans within collapsed debris and accurately buried locations of the humans, inputs of considerable time and manpower for rescuing them are required. Besides, secondary damage can be occurred by additional collapses. The aim of this study is to propose a stochastic location positioning method that enables to provide aid information by determining locations of mobile devices for buried persons in 2-D plane using wireless communication technologies. This study selected a detection method for buried persons based on Wi-Fi signal, and identified characteristics of signal strengths by distance unit. Using these methods, a stochastic location detection model in 2-D plane was built. It is expected that this technology will be utilized as a core technology that can protects safety and human life of the public by providing data for rescuing quickly buried persons in cases of national disasters for future.

• The Journal of Engineering Geology
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• v.19 no.1
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• pp.81-88
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• 2009

Two dimensional Monte-Carlo simulations of a non-reactive solute plume in isotropic porous media which are physically and chemically heterogeneous are conducted to determine the variations of moment. Retardation factors of 1, 2 and 5 are given to ascertain how the second moments are changed as adsorption increased. Retarded longitudinal second spatial moment, ${Z_{11}}^{'R}(t',l')$, increased during the transport process and as the dimensionless lengths of line plume source, $l_2'$, increased. ${Z_{11}}^{'R}(t',l')$ decreased as the retardation factors increased, and the simulated moments fit well to the first-order analytical results. Retarded longitudinal plume centroid variance, ${Z_{11}}^{'R}(t',l')$, decreased as the dimensionless lengths of line plume source, $l_2'$, increased and as the retardation factor increased. The result indicates that the uncertainty about the plume center decreased, and the ergodic condition for the second spatial moments is far from reaching. Simulated longitudinal one particle displacement covariance, ${Z_{11}}^{'R}(t')$, well consistent with the first-order analytical results for the three degrees of retardation factors of 1, 2 and 5 respectively. It is, consequently, concluded that the retarded longitudinal second moments could be produced by stochastic simulation, and that the first-order analytical results definitely provides very close values of the longitudinal retarded moments.