• 태양에너지
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• 제12권1호
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• pp.25-33
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• 1992

정상상태에서 고온부가 존재하는 밀폐공간내의 자연대류 열전달을 $Gr=1.5{\times}10^5$, Pr=0.71 및 $k_s/k_f=14710$ 조건에서 경사각을 변화시켜 연구하였다. 고온부는 밀폐공간 면적의 1/25 을 차지하고 형상비는 1.0이다. 전체평균 누셀트 수는 경사각을 증가시키면 감소하였고 ${\theta}=90^{\circ}$인 경우가 ${\theta}=0^{\circ}$ 일때보다 14% 낮게 나타났다.

• Animal cells and systems
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• 제11권1호
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• pp.9-15
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• 2007

The naphthoquinone analog (2,3-dichloro-6,9-dihydroxy-1,4-naphtoquinone, NA) has an inhibitory effect on cdc25A protein phosphatase in vitro, which is responsible for G1/S transition during cell cycle. However, the exact mechanism inducing the growth inhibition is not understood. In this study, we investigated the regulatory mechanisms of growth arrest induced by NA, as a new potent inhibitor of cdc25A phosphatase, in human hepatocarcinoma SK-hep-1 cells. We found that NA induced the G1 arrest by perturbation of protein tyrosine dephosphorylation of Cdk2, which may be resulting from inhibition of cdc25A phosphatase. In addition, p21 was expressed in a p53-independent manner and participated in the NA-induced G1 arrest by inhibiting Cdk2 activity. Although the exact mechanism is not known, the p21 expression might be related to MAPK activation. From these results, we suggest that NA induces G1 arrest via inhibition of cdc25A and induction of p53-independent p21 expression in SK-Hep-1 cells.

• Asian-Australasian Journal of Animal Sciences
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• 제9권1호
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• pp.37-44
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• 1996

The present study was conducted to investigate the role of thyroid hormones in the regulation of gene expression of calbindin-$D_{28k}$ (CaBP-D28K) in the chicken. By employing slot blot and RIA analyses, levels of CABP-D28K mRNA and CaBP-D28K protein in the intestine, kidney, cerebellum and liver were measured 6 and 12 h after i.m. injection of 1, 25-dihydroxyvitamin $D_3$ [1, 25 $(OH)_2D_3$; 250 ng/chick] and 3, 5, 3'-triiodothyronine ($T_3$; 500 ng/chick) in one-day-old chicks. The abundant messages of CaBP-D28K mRNA were detected in the intestine, kidney and cerebellum while there was little message in the liver. After 1, 25 $(OH)_2D_3$ treatment (6 + 12 hours), levels of CaBP-D28K mRNA increased in the intestine, but there was no change in the mRNA levels in the kidney and cerebellum. Although $T_3$ alone had no effect on CaBP-D28K mRNA levels, simultaneous administration of $T_3$ enhanced the 1, 25 $(OH)_2D_3$ effect of levels of CaBP-D28K mRNA in the intestine both 6 and 12 h post-treatment, and in the kidney 12 h post-treatment. At a protein level, co-treatment with 1, 25 $(OH)_2D_3$ and $T_3$ elicited a significant increase in CaBP-D28K expression in the intestine 12 h post-treatment, as compared to treatment with only 1, 25 $(OH)_2D_3$, whereas no differences were observed in the CaBP-D28K protein levels in the kidney and cerebellum. These results suggest that thyroid hormones may play a synergistic role with 1, 25 $(OH)_2D_3$ for CaBP-D28K gene expression in the intestine and kidney in chicks.

• ETRI Journal
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• 제28권1호
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• pp.9-16
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• 2006

In this paper, we analyzed and measured the electrical crosstalk characteristics of a 1.25 Gbps triplexer module for Ethernet passive optical networks to realize fiber-tothe-home services. Electrical crosstalk characteristic of the 1.25 Gbps optical triplexer module on a resistive silicon substrate should be more serious than on a dielectric substrate. Consequently, using the finite element method, we analyze the electrical crosstalk phenomena and propose a silicon substrate structure with a dummy ground line that is the simplest low-crosstalk layout configuration in the 1.25 Gbps optical triplexer module. The triplexer module consists of a laser diode as a transmitter, a digital photodetector as a digital data receiver, and an analog photodetector as a cable television signal receiver. According to IEEE 802.3ah and ITU-T G.983.3, the digital receiver and analog receiver sensitivities have to meet -24 dBm at $BER=10^{-12}$ and -7.7 dBm at 44 dB SNR. The electrical crosstalk levels have to maintain less than -86 dB from DC to 3 GHz. From analysis and measurement results, the proposed silicon substrate structure that contains the dummy line with $100\;{\mu}m$ space from the signal lines and 4 mm separations among the devices satisfies the electrical crosstalk level compared to a simple structure. This proposed structure can be easily implemented with design convenience and greatly reduce the silicon substrate size by about 50 %.

• 한국환경보건학회지
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• 제10권2호
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• pp.89-97
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• 1984

The possible effects of garlic (Aliium sativurn L.) extract on growth and aflatoxin production by Aspergillus parasiticus R- 716 were investigated. Various solvent extracts of garlic strongly inhibited growth and sporulation by Aspergillus parasiticus R-716, and effective solvents used for extraction of garlic were chloroform, benzene, and water-chloroform. The growth and aflatoxin production decreased with the increase in extract concentration, and extract equivalent 1.5g of raw garlic weight in 25ml SLS medium completely inhibited, and at a level of 1.25g garlic, total aflatoxin was reduced 64% (472 ${\mu}g$/25ml) of that produced in the control (1, 352 ${\mu}g$/25 ml). During cultivation inhibitory rate of growth was reduced from 89.1% to 40% and aflatoxin $B_2$, $G_1$ production increased with the laps of time. Especially garlic extract appeared to have a stimulatory effect on lipid accumulation on the contrary aflatoxin production.

• 유기물자원화
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• 제26권2호
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• pp.65-73
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• 2018

본 연구는 음식물쓰레기의 발효건조를 위한 최적 운전조건을 도출하기 위하여 0.75, 1.00, 1.25, $1.50L/min{\cdot}kg$의 송풍조건에서 발효건조 회분식 반응기를 20일간 운전하였으며, Modified Gompertz 모델을 이용하여 발효건조 기간 중 반응기내에서의 유기물 분해반응속도를 분석하였다. 유기물 분해 반응속도 분석에서 최대 유기물 분해량 (P)은 송풍량 0.75, 1.00, 1.25, $1.50L/min{\cdot}kg$에서 각각 2.31, 2.52, 2.27, 1.88 kg이었으며, 최대 유기물 분해속도 ($R_m$)는 송풍량 0.75, 1.00, 1.25, $1.50L/min{\cdot}kg$에서 각각 0.33, 0.45, 0.28, 0.18 kg/day를 보여 송풍량 $1.00L/min{\cdot}kg$에서 우수한 유기물 분해효율을 보였다. 발효건조 반응기의 지체성장시간 (${\lambda}$)은 송풍량 0.75, 1.00, 1.25, $1.50L/min{\cdot}kg$에서 각각 2.10, 1.48, 1.15, 1.06 일로 나타나 $0.75L/min{\cdot}kg$의 적은 송풍조건에서 가장 긴 지체성장시간을 보여 송풍량의 증가는 지체성장시간을 단축시키는 것으로 나타났다. 음식물쓰레기 발효건조 반응기의 운전에서 수분 제거율은 발효건조 반응기 운전 초기에서 중기로 갈수록 송풍량 증가와 함께 증가하다가 발효건조 반응기 운전 말기에는 송풍량 $1.00L/min{\cdot}kg$에서 가장 높은 수분 제거율을 보여 발효건조의 최적 송풍조건은 $1.00L/min{\cdot}kg$으로 나타났다.

• 한국안광학회지
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• 제6권1호
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• pp.139-144
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• 2001

색각 검사용 Farnsworth Test Panel D-15를 CIELab color space 좌표에서 분석하기 위해 380~780nm의 반사광 spectrum 세기를 측정하였다. Test Panel D-15는 CIELab의 좌표(a,b)상에서 채도가 앞은 원점 근방에 위치하였다. 정상인은 색 차가 작은 색을 비슷한 색으로 지각하였고, 색각 이상자는 색차와 무관한 혼돈색 line과 중성점에 의존하였다. 색각이상인 제1색각 이상, 제2색각 이상, r-g defect, y-b defect의 경우 중성점 위치(a,b)는 각각(2.12, 1.02), (4.25, 2.05), (2.51, 0.25), (1.20, -1.10)였다.

• E2M - 전기 전자와 첨단 소재
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• 제8권3호
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• pp.267-271
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• 1995

The electrical properties of (S $r_{0.50}$P $b_{0.25}$B $a_{0.25}$)Ti $O_{3}$ ceramics were studied. Specimens were prepared by the conventional mixed oxide method, and fired between 1300[.deg. C] - 1375[.deg. C], for 2[hr.]. The electrical and structural preperties of specimens were investigated with sintering temperature. Increasing the sintering temperature from 1300[.deg. C] to 1375[.deg. C], average grain size was increased from 2.61[.mu.m] to 4.53[.mu.m]. (S $r_{0.50}$P $b_{0.25}$B $a_{0.25}$)Ti $O_{3}$ specimen sintered at 1350[.deg. C] for two hours showed good dielectric constant(2147) and dielectric loss(1.7[%]) properties at 1[khz]. Sintered density and breakdown field strength were the highest value of 5.75[g/c $m^{3}$], 20[kV/cm], respectively. Dielectric properties with applied voltage were independent of the sintering temperature.temperature.

• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.305-308
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• 2012

Objective: To assess the health and economic burden of human papillomavirus (HPV)-related diseases (cervical cancer, cervical intraepithelial neoplasia (CIN) 1/2/3, and genital warts) in Singapore over a period of 25 years beginning in 2008. Methods: Incidence-based modeling was used to estimate the incidence cases and associated economic burden, with the assumption that age-stratified incidence rates will remain the same throughout the period of 25 years. The incidence rates in 2008 were projected based on data obtained from the National Cancer Registry for cervical cancer, and from a combination of published data and hospital registry review for CIN1/2/3 and genital warts. The population growth rate was factored into the projection of incidence cases over time. Direct cost data per cervical cancer and per CIN1/2/3 case were obtained from the financial database of large local hospitals while cost data for genital warts were obtained from the National Skin Center; these costs were multiplied by the number of incidence cases to produce an aggregate estimate of the economic burden over the 25-year period (in 2008 Singapore dollars) using a 3% discount rate. Results: The total number of incidence cases of HPV-disease over 25 years beginning in 2008 was estimated to be 60,183, including 8,078 for cervical cancer, 11,685 for CIN 2/3, 8,849 for CIN1, and 31,572 for genital warts. The estimated total direct cost was 83.2 million Singapore Dollars over 25 years: 57.6 million attributable to cervical cancer, 13.0 million to CIN2/3, 6.83 million to CIN1, and 5.70 million to genital warts. Conclusion: HPV-related diseases are expected to impose significant health and economic burden on the Singapore healthcare resources in the next 25 years.

• 한국식품저장유통학회지
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• 제6권4호
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• pp.371-375
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• 1999

쓰가루사과를 차압예냉처리하여 1$^{\circ}C$와 $25^{\circ}C$에 저장한 경우 표면색택의 변화는 예냉처리구가 변화가 적게 나타났다. $25^{\circ}C$에 저장하였을 경우 a값은 저장기간중 거의 차이를 보이지 않았고 b값은 저장기간중 크게 증가하였으나 1$^{\circ}C$에서는 a, b값 모두 저장 1개월후까지도 거의 차이를 보이지 않았다. 경도 및 총산도는 저장기간이 경과할수록 감소하였으며 예냉구의 경우가 총산도의 감소가 적게 나타났는데 무예냉구의 경우 저장기간이 길어질수록 변화폭이 크게 나타났다. 쓰가루 사과의 유리당의 구성은 fructose가 7.07%로 가장 많으며 다음은 glucose가 2.85%, sucrose 가 2.53% 순으로 나타났다. $25^{\circ}C$에 저장한 경우 유리당의 변화는 저장기간중 모두 감소하였으나 1$^{\circ}C$에 저장한 경우는 fructose와 glucose는 계속 감소한 반면 sucrose는 약간 증가하였다. 한편 예냉처리한 사과의 경우 유리당 함량의 변화가 무예냉구에 비하여 낮게 나타났다.