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Clinical study of Acupuncture effect on Chronic Headache (천식(喘息)의 침구치료(鍼灸治療)에 관(關)한 문헌적(文獻的) 고찰(考察))

  • Rhee, Sung-Hwan;Kim, Chang-Hwan;Lee, Yun-Ho
    • Journal of Acupuncture Research
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    • v.17 no.3
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    • pp.36-44
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    • 2000
  • The purpose of this study is to arrange the acupuncture therapy on the asthma from the oriental medical literature. The results obtained as follows. 1. The cause of the asthma is the intrinsic factors and the over-sensitive reactions. The decreased function of the lung and the kidney are chronically affected to the asthma. 2. The typical sign of the asthma is tachypnea and wheezes to be heard throughout the lung field, particularly during expiration. 3. Bladder meridian, Conception vessel, and Lung meridian used frequently for the acupuncture therapy, and Bladder meridian, Conception vessel, Stomach meridian, and Lung meridian used frequently for the moxibusrion on the asthma. The acupuncture points of Lung meridian used most frequently on the asthma, but the acupuncture points of Heart meridian have not used. 4. Acupuncture point at B13, CV22, LI4, CV12, CV17, 536, B12 used used frequently for the acupuncture therapy, and the acupuncture point at B13, CV22, B12, CV17, B43 used frequently for the moxibustion on the asthma Particularly B13 and CV22 used most frequently for the acupuncture therapy on the asthma.

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Expected Probability Weighted Moment Estimator for Censored Flood Data (절단된 홍수 자료에 대한 확률가중적률 추정량)

  • Jeon, Jong-June;Kim, Young-Oh;Kim, Yong-Dai;Park, June-Hyeong
    • Proceedings of the Korea Water Resources Association Conference
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    • 2010.05a
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    • pp.357-361
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    • 2010
  • 미래의 연별 최대 강수량 예측의 정확성을 향상시키는데 역사적 자료가 도움이 된다는 많은 연구 결과가 있었다. 관측의 오차와 자료의 손실로 역사자료를 이용한 강수 예측 방법은 절단자료의 분석을 중심으로 연구되었다. 대표적인 역사자료의 이용방법으로 조건부 적률을 이용한 B17B [Interagency Committee in Water Data, 1982], 조건부적률과적률 관계식을 이용한 Expected Moment Algorithm(EMA) [Cohn et al.;1997], 조건부 확률가중적률을 이용한 Partial Probability Weighted Moment (PPWM)[Wang ; 1991] 방법이 있다. 본 연구에서는 역사적 자료를 반영하는 방법에 있어 B17B와 EMA의 관계를 밝히고 그러한 관계가 PPWM에 동일하게 적용할 수 있음을 보였다. 우리는 B17B와 EMA의 관계를 적률방정식으로 표현하였고 PPWM에서 확률가중 적률 방정식을 정의함으로써 PPWM을 확장하였다. 본 연구에서 제안한 새로운 역사 자료를 이용한 강수예측 방법론을 Expected Probability Weighted Momemt (EPWM) 방법이라고 부르고 그 예측 방법의 성능을 다른 예측방법과 시뮬레이션 결과를 통해 비교하였다. 역사 자료 방법론의 비교는 Generalized Extreme Value (GEV) 분포를 이용하여 이루어졌으며, 각 방법론은 GEV분포의 형태모수(shape parameter)따라 다른 특성을 나타난다는 것을 보였다. 뿐만 아니라 여기서 제안한 EPWM 방법은 대부분의 경우에 좋은 추정량을 준다는 것을 보였다.

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Genetic Differences within and between Populations of Korean Catfish (S. asotus) and Bullhead (P. fulvidraco) Analysed by RAPD-PCR

  • Yoon, Jong-Man;Kim, Jong-Yeon
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.8
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    • pp.1053-1061
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    • 2004
  • Of the 20 arbitrarily chosen primers, six oligonucleotides decamer primers were used on the basis of the number of the polymorphisms generated in catfish (Silurus asotus) from Yesan and bullhead (Pseudobagrus fulvidraco) from Dangjin in Korea. Six primers were used generating a total of 602 scorable bands in catfish and 195 in bullhead population, respectively, ranging in size of DNA fragments from less than approximately 100 to larger than 2,000 base pairs (bp). Six primers yielded 199 polymorphic fragments (33.1%) in catfish and 47 (24%) in bullhead, respectively. In the present study, a total of 328 common fragments (an average of 54.7 per primer) were observed in catfish population, whereas 84 (an average of 14.0 per primer) in bullhead. The total number of specific fragments in catfish and bullhead population were 76 and 64, respectively. In catfish population, random decamer, OPA-17 (GACCGCTTGT) generated the highest number of fragments (a total of 141) in comparison with other primers used, with an average of 11.8. The common bands in the molecular weight of 300 bp generated by random primer OPA-06 (GGTCCCTGAC) were present in every individuals in bullhead population. The major polymorphic bands in the molecular weight of 100 bp generated by OPA-17 were identified in lane 14, 15, 17, 18, 19 20 and 21, which were identifying species in bullhead population. The average bandsharing values (BS values) of all of the samples within catfish population ranged from 0.575 to 0.945, whereas 0.063-1.000 within bullhead population. The bandsharing value (index of similarity between individuals) between individual No. 5 and No. 9 showed the highest level within catfish population, whereas the bandsharing value between individual No. 1 and No. 2 showed the lowest level. The single linkage cluster analysis resulted from four primers, indicating four genetic groupings composed of group 1 (C1-C10, all of the catfish samples), group 2 (B11, B12, B13, B14, B16, B17, B18, B19), group 3 (B15) and group 4 (B20 and B21). The dendrogram reveals close relationships between individual identities within two species populations and individuals derived from the same ancestor, respectively. However, genetic distances between two species populations ranged from 0.124 to 0.333. The shortest genetic distance (0.042) displaying significant molecular differences was between individual No. 6 and No. 9 catfish population. The shortest genetic distance (0.033) displaying significant molecular differences also was between individual No. 18 and No. 19 in bullhead population. Reversely, the genetic distance of individual No. 20/21 among individuals in bullhead population was highest (0.333). This result showed that bullhead No. 20 and 21 were distinct from other individuals within bullhead population.

Determination of metabolites of prostanozol in human urine by LC/ESI/MS and GC/TOF-MS (LC/ESI/MS와 GC/TOF-MS를 이용한 인체뇨시료에서의 Prostanozol 대사체 검출)

  • Yum, Tae-Woo;Paeng, Ki-Jung;Kim, Yun-Je
    • Analytical Science and Technology
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    • v.24 no.3
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    • pp.173-182
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    • 2011
  • This research examined prostanozol and its metabolites in urine of women who took the medicine (prostanozol). Prostanozol and its metabolites were successfully separated and detected by using LC/ESI/MS and GC/TOF-MS. Mass spectrum of LC/ESI/MS estimated molecular weight of Prostanozol and its metabolites and that of GC/TOF-MS verified them. For M1, carbon number 17 of Prostanozol substituted to a keto group and it is called 17-keto-Prostanozol. M2 turned out to be hydroxy-17-keto-Prostanozol. It came from substitution of one hydroxyl group of pyrazole nucleus and A-ring of M1. Substitution of one hydroxyl group of B-ring or C-ring became M3, hydroxy-17-keto-Prostanozol. M4 was found to be a hydroxy-17-keto-Prostsnozol transposed from one hydroxyl group to a D-ring. M5 has a hydroxyl group of carbon number 17. One hydroxyl group is substituted from B-ring or C-ring and it is assumed to be hydroxy-17-hydroxy-Prostanozol. M6 was turned out to be dihydroxy-17-keto-Prostanozol transposed from one hydroxyl group to pyrazole nucleus or A-ring and to B-ring or C-ring. Like M6, M7 has a keto group at carbon number 17 and was identified as dihydroxy-17-keto-Prostanozol. M7 has one hydroxyl group at pyrazole nucleus or A-ring and also at D-ring. At last M8 was found to be dihydroxy-17-hydroxy-Prostanozol. Pyrazole nucleus or A-ring has got one hydroxyl group and other rings were substituted to another hydroxyl group. From above, M5, M7 and M8 were verified as new metabolites that were not discovered yet. Prostanozol and all of the 8 metabolites formed glucuronic conjugates as a result of conjugation reaction test in human body. Some of 8 metabolites were excreted without forming conjugates. Particularly M6 and M7 were excreted as sulfate conjugates.

Higher Expression of TRPM7 Channels in Murine Mature B Lymphocytes than Immature Cells

  • Kim, Jin-Kyoung;Ko, Jae-Hong;Nam, Joo-Hyun;Woo, Ji-Eun;Min, Kyeong-Min;Earm, Yung-E;Kim, Sung-Joon
    • The Korean Journal of Physiology and Pharmacology
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    • v.9 no.2
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    • pp.69-75
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    • 2005
  • TRPM7, a cation channel protein permeable to various metal ions such as $Mg^{2+}$, is ubiquitously expressed in variety of cells including lymphocytes. The activity of TRPM7 is tightly regulated by intracellular $Mg^{2+}$, thus named $Mg^{2+}$-inhibited cation (MIC) current, and its expression is known to be critical for the viability and proliferation of B lymphocytes. In this study, the level of MIC current was compared between immature (WEHI-231) and mature (Bal-17) B lymphocytes. In both cell types, an intracellular dialysis with $Mg^{2+}$-free solution (140 mM CsCl) induced an outwardly-rectifying MIC current. The peak amplitude of MIC current and the permeability to divalent cation ($Mn^{2+}$) were several fold higher in Bal-17 than WEHI-231. Also, the level of mRNAs for TRPM7, a molecular correspondence of the MIC channel, was significantly higher in Bal-17 cells. The amplitude of MIC was further increased, and the relation between current and voltage became linear under divalent cation-free conditions, demonstrating typical properties of the TRPM7. The stimulation of B cell receptors (BCR) by ligation with antibodies did not change the amplitude of MIC current. Also, increase of extracellular $[Mg^{2+}]_c$ to enhance the $Mg^{2+}$ influx did not affect the BCR ligation-induced death of WEHI-231 cells. Although the level of TRPM7 was not directly related with the cell death of immature B cells, the remarkable difference of TRPM7 might indicate a fundamental change in the permeability to divalent cations during the development of B cells.

Analysis of Power Amplifier Phase Distortion Characteristics for IEEE 802.11a OFDM Wireless LAM Using Phase Predistortion (사전위상 왜곡을 이용한 IEEE 802.11a OFDM 무선랜 전력증폭기 위상왜곡 특성분석)

  • Oh Chung Gyun;Choi Jae Hong;Koo Kyung Heon
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.42 no.2 s.332
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    • pp.75-80
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    • 2005
  • In this paper, 2-stage power amplifier has been designed for 5.8GHz wireless LAN application. The power amplifier PldB output power has 21.6dBm at 5.8GHz frequency. Also the power amplifier shows 17.6dB gain and -17.8dB input return loss at 5.725GHz to 5.825GHz. The OFDM modulation and transmission block have been modeled in order to analyse the relationship between the power amplifier distortion and output ACPR for the IEEE 802.11a wireless LAN. The nonlinear characteristic of the power amplifier has been modeled as AM-to-AM and AM-to-PM using the behavioral model, and the output spectrum is analysed with the phase distortion variation. Also, amplifier back-off value from PldB to satisfy the required IEEE 802.11a standard spectrum mask has been simulated with phase distortion, and the simulation data have been compared to the measurement result collected by using the pre-distortion technique.

The Design and Fabrication of X-Band MMIC Low Noise Amplifier for Active antennal using P-HEMT (P-HEMT를 이용한 능동 안테나용 X-Band MMIC 저잡음 증폭기 설계 및 제작)

  • 강동민;맹성재;김남영;이진희;박병선;윤형섭;박철순;윤경식
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.9 no.4
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    • pp.506-514
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    • 1998
  • The design and fabrication of X-band(11.7~12 GHz) 2-stage monolithic microwave integrated circuit(MMIC) low noise amplifier (LNA) for active antenna are presented using $0.15{\mu}m\times140{\mu}m$ AlGaAs/InGaAs/GaAs pseudomorphic high electron mobility transistor (P-HEMT). In each stage of the LNA, a series feedback by using a source inductor is used for both input matching and good stability. The measurement results are achieved as an input return loss under -17 dB, an output return loss under -15dB, a noise figure of 1.3dB, and a gain of 17 dB at X-band. This results almost concur with a design results except noise figure(NF). The chip size of the MMIC LNA is $1.43\times1.27$.

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Rotational Contour Analysis of the Vibronic Bands in the High Resolution Emission Spectra of the Benzyl Radical

  • 최익순;한명선;이상국
    • Bulletin of the Korean Chemical Society
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    • v.17 no.10
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    • pp.882-885
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    • 1996
  • The 6a10 and 6b10 vibronic bands in the 12A2-12B2 electronic transition of the emission spectra of the benzyl radical obtained using a high resolution Fourier transform spectrometer are rotationally analyzed. The observed rotational contours were fitted by computer simulated rotational contours, providing determination of the variations, ΔA, ΔB, and ΔC of the rotational constants accompanying the vibronic transitions corresponding to each band. The molecular rotational constants A, B, and C are revised for the upper state and for the two lower states, respectively.

Effects of 17b-Estradiol on the Inducible Nitric Oxide Synthase Expression in macrophages

  • Kim, Ji-Young;Cho, Young-Rhan;Jeong, Hye-Gwang
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.171.1-171.1
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    • 2003
  • In some tissues 17b-estradiol (E2) is known to increase endothelial NOS expression. In the present study we examined the effects of E2 on estrogen receptors (ERa and b) and inducible nitric oxide synthase (iNOS) expression and analyzed the mechanisms in rat peritoneal macrophages. (omitted)

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