• Clinical and Experimental Pediatrics
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• v.53 no.2
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• pp.195-202
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• 2010

Purpose : Despite recent advances in pulmonary hypertension management and surgery, appropriate guidelines remain to be developed for operability in congenital heart disease with pulmonary artery hypertension (PAH). Our aim was to evaluate clinical outcomes of patients with severe PAH who underwent surgical closure of left-to-right shunt lesions (LRSL) on the basis of pulmonary reactivity. Methods : We retrospectively reviewed 21 patients who underwent surgical closure of LRSL with severe PAH (${\geq}8$ Wood unit) from January 1995 to April 2009. The median age at operation was 26 years. Atrial septal defect, ventricular septal defect (VSD), VSD and patent ductus arteriosus (PDA), and PDA was present in 11, 4, 4, and 2 patients, respectively. Results : Operability was based on vasoreactivity of PAH. Of the 21 patients, 5 showed response to pulmonary vasodilator therapy and 8 showed vasoreactivity after balloon occlusion of defects. The remaining 8 patients were considered operable because of significant left-to-right shunt (Qp/Qs ${\geq}1.5$). Five patients underwent total closure of defects and 16 were left with small residual shunts. The median follow-up duration was 32 months. There was no significant postoperative mortality or morbidity. Systolic pulmonary artery pressure (PAP) decreased in all but 2 patients. All patients except 1 showed improvement of New York Heart Association functional class. Conclusion : Closure of LRSL in patients with severe PAH on the basis of pulmonary vasoreactivity seems reasonable. PAP and clinical symptoms improved in most patients. Further research is needed for the evaluation of long-term results.

• Journal of Environmental Science International
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• v.16 no.3
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• pp.247-253
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• 2007

Polycyclic aromatic hydrocarbons (PAHs) are a major concern because of their potential mutagenic and carcinogenic risks to human beings. One of these harmful, yet commonly observed PAHs is pyrene. Pyrene is one of the 16 PAHs listed by the United States Environmental Protection Agency as priority pollutants. The purposes of this research are to develop a method of pretreatment for PAH contaminants prior to a typical biological treatment and to demonstrate the biodegradablity of these compounds. Since pyrene is non-polar, hexane was chosen as a solvent to effectively dissolve pyrene. Pyrene solutions were treated with ozone, as it has hish oxidation capacity and electrophilic character. The intermediates and byproducts of pyrene were dissolved in alkaline water at pH 11.4 and neutralized to test for $BOD_5$, COD, and toxicity. These solutions were further ozonated and assessed of biodegradability. The first-order rate constant to was found to be between $0.121day^{-1}$ and $0.081 day^{-1}$, depending on the duration of reozonation. The $BOD_5/COD$ ratio was found to 0.66. The toxicity test showed that after 10 min of reozonation time, the byproducts and intermediates of pyrene were within the lion-toxic range of ${\pm}10%$ inhibition for E-Coli bacteria.

• Korean Journal of Microbiology
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• v.39 no.2
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• pp.108-113
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• 2003

Diesel oil-degrading bacterial strains were isolated from diesel oil contaminated soil and called HS series (HS1, HS2 and HS3). These strains were identified as Acinetobacter sp. (HS1) and Pseudomonas sp. (HS2 and HS3) based on Biolog test, cellular fatty acid composition, and 16S rDNA sequence analysis. These strains were coltivated in liquid minimal media containing 2% diesel oil, and diesel oil-degrading activity was measured. As result, all strains degraded over 70% of total diesel oil. But PAH (polycyclic aromatic hydrocarbon)- and pris- tane-degrading rate of these strain was below 20％ of total PAH and pristane. The HS 1 strain showed highest hydrophobicity and low emulsifying activity among the experimental strains and high diesel oil-degrading activity. From the above-mentioned result, microcosm experiment was performed with the HS1 strain. The HS1 strain showed a degrading activity of over 80% of total diesel oil in microcosm test. And microbial activity was correlated to diesel oil-degrading activity. Therefore, it is suggested that the HS1 strains could be effectively used for the bioremediation for diesel oil.

• Journal of Environmental Science International
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• v.14 no.2
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• pp.105-119
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• 2005

The surface sediments inside Songsanpo and Seogwipo Harbors, major harbors of Jeju Island, were collected three times (June, September and December, 2001) and analyzed for 16 polycyclic aromatic hydrocarbons (PAHs) recommended by US-EPA as priority pollutants to assess their distribution levels and their biological effects on the marine organisms, and to suggest their possible origins. The concentrations of total PAHs inside Songsanpo and Seogwipo Harbors ranged from 41 to 288 ng/g on a dry weight basis with a mean value of 121 ng/g and from 14 to 268 ng/g with a mean value of 119 ng/g, respectively, and the levels were low as compared with those in other areas of the world. The sedimentary PAHs may be correlated with organic carbon and mud content to some extent. Based on comparisons of individual and total concentrations with effects-based sediment quality guidelines, the potential for the biological effects on the marine organisms were expected to be very low. From the examinations of the four PAH origin indices, such as LMW /HMW (low molecular weight 2-3 ring PAHs over high molecular weight 4-6 ring PAHs), phenanthrene/anthracene ratio, fluoranthene/pyrene ratio, chrysene/benzo[a]anthracene ratio, it can be concluded that the sediment PAH contaminations were ascribed to both of pyrolytic and petrogenic origins.

• Journal of Environmental Science International
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• v.25 no.11
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• pp.1459-1466
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• 2016

In this study, the concentrations of polycyclic aromatic hydrocarbons (PAHs) were investigated in meat process food and for cooking methods (pan-frying and charcoal fire). The methodology involved liquid-liquid extraction, silica gel cartridge clean-up and determination by gas chromatography/mass spectrometry (GC/MS). The recovery of 17 PAHs spiked into these samples ranged from 66.6 % to 98.0% and the coefficient of variation was less than 10%, but that of dibenz(a,h)anthracene was 16.39%. The mean concentration of total PAHs in processed samples was ND~7.2 ng/g, whereas that pan-fried and charcoal-fired samples were ND~22.1 ng/g and, 12.7~367.8 ng/g, respectively. Therefore, the concentrations of total PAHs in cooked samples were higher than in original samples and charcoal-fired samples had the highest total PAH levels.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.43 no.6
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• pp.705-714
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• 2010

The residual oil concentrations in seawater and sediments were investigated along the Taean coast of Korea, following the Hebei Spirit oil spill, which occurred on 7 December 2007. The oil concentration in seawater ranged from 0.059 to $0.866\;{\mu}g/L$ for the tidal flat culture grounds and from 0.016 to $0.943\;{\mu}g/L$ in the fish cage areas in 2008. These were dominated by the seawater temperature relationship. Polycyclic aromatic hydrocarbons (PAHs) in sediments were also analyzed and the concentrations ranged from 3.4 to 509.7 ng/g dry weight. The average PAH level was higher in seawater from the Sinduri area than the Padori area, while the average PAH level in sediments was higher in Padori. The diagnostic ratio of PAHs was investigated to determine the origins of the PAHs. The PAHs in the Seongam area, which was not affected by the oil spill, are of pyrolytic origin, while the PAHs in Padori and Sinduri were of petrogenic origin. The residual oils in the areas affected by the oil spill tended to decrease over time, except in summer. The oils in pore water remained 6- to 16-fold higher, as compared to the seawater overlying the tidal flat, implying that residual oils will continue to influence the affected region for the foreseeable future.

• Journal of Environmental Science International
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• v.2 no.1
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• pp.57-68
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• 1993

Polycyclic aromatic hydrocarbons (PAMs) are ubiquitous contaminants in marine environments. PAHs enter estuarine and nearshore marine environment via several routes such as combustion of fossil fuels, domestic and industrial effluents and oil spills PAHs have been the focus of numerous studies in the world because they owe potentially carcinogenic, mutagenic, and teratogenic to aquatic organisms and humans from consuming contaminated food. However, one can hardly find any available data on PAM content in marine organisms in Korea. The present study was carried out in order to determine PAH content in oysters from the intertidal and subtidal zones of Chinhae Bay, which is located in near urban communities and an industrial complex, and the bay is considered to be a major repositories of PAHs. 16 PAHs were analyzed by High Performance Liquid Chromatography (HPLC) with uv/vis and fluorescence detectors in oysters: they are naphthalene (NPTHL), acenaphthylene (ANCPL), acenaphthene (ACNPN), fluorene (FLURN), phenanthrene (PKEN), anthracene (ANTHR), fluoranthene (FLRTH), pyrene (PYRf), benzo(a)anthracene (BaA), chrysene (CHRY), benzo(b)- fluoranthene (BbF), benzo(k)fluoranthene (BkF), benzo(a)pyrene (BaP), dibenz(a, h)anthracene (DhA), benzo(g, h, i)peryne (Bghip) and indeno(1, 2, 3, -cd)pyrene (I123cdP). The PAH contents in oysters from the intertidal and subtidal zones of Chinhae Bay ranged from < 0.1 to 992.0 $\mu\textrm{g}$/kg (mean 69.8 $\pm$ 9.8 $\mu\textrm{g}$/kg). Key words . polycyclic aromatic hydrocarbon, high performance liquid chromatography, oyster, Chinhae Bay.

• Journal of Soil and Groundwater Environment
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• v.27 no.2
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• pp.50-60
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• 2022

The concentration levels and distribution characteristics of 16 polycyclic aromatic hydrocarbons (PAHs) were investigated and evaluated for total 100 soil samples as a part of the survey on soil contamination in Gwangju. The results (median and range) of T-PAHs (sum of 16 PAH concentrations), C-PAHs (sum of carcinogenic PAH concentrations) and T-TEQs (sum of 16 TEQ concentrations) were 20.8 (7.6~1158.1), 2.2 (N.D~509.6), and 0.3 (N.D~424.6) ㎍/kg, respectively. There was a positive correlation between C-PAHs/T-PAHs and T-TEQs/T-PAHs except one point where the concentration of benzo(a)pyrene was high. The ratios of the C-PAHs/T-PAHs were 31.7% for low molecular weight-PAHs and 68.3% for high molecular weight-PAHs, suggesting that PAHs generation mainly arose from combustion sources. The ratio of isomers of individual PAHs, Phe/Ant, Flu/Pyr, Ant/(Ant+Phe), Flu/(Flu+Pyr), and BaA/(BaA+Chr), also confirmed the predominance of PAHs from combustion activities. Statistical tracing of the source of PAHs through principal component analysis indicated that the main sources of combustion were automobile fuel and coal. The overall results of this study suggested HMW-PAHs, T-PAHs, C-PAHs and T-TEQs should be separately evaluated to better assess the toxicity and environmental behavior of individual PAHs.

• Environmental Analysis Health and Toxicology
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• v.16 no.4
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• pp.171-179
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• 2001

A new passive sampler was developed, improving SPMD (Semipermeable Membrane Devices) that contained triolein in nonporous, low-density polyethylene layflat tubing. Experiments to measure PAHs concentration were carried out at four sites (Dukpo, Sochi, Sohwonggando, Yeonmok) on the southern coast of Korea that were contaminated by oil spills. Passive samplers were deployed at 4 and 8 week intervals at each site. Results showed that bioconcentration levels of PAHs were increased in proportion to exposure duration from all sample sites and accumulation in the passive sampler was much higher than in biota at the Dukpo site. Results of these tests suggest that new passive sampler is a useful tool for measuring bioconcentration organic compounds in aquatic environments.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2006.04a
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• pp.16-19
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• 2006

Humin is the insoluble fraction of humic materials and play an important roles in the irreversible sorption of hydrophobic organic contaminants onto soil particles. However, there have been limited knowledge about the sorption and chemical properties of humin due to the difficulties in its separation from the inorganic matrix(mainly clays and oxides). In this study, do-ashed humin was isolated from a soil sample after removing free lipid and alkali-soluble humic fractions followed by dissolution of mineral matrix with 2% HF, and characterized by elemental analysis, C-13 NMR spectroscopic method. Sorption behavior of 1-naphthol with humin was also investigated from aqueous solution. C-13 NMR spectra indicate that humin molecules are mainly made up of aliphatic carbon including carbohydrate, methylene chain etc.. Sorption intensity for 1-naphthol was increased as organic carbon content of humin increased and log Koc values for the 1-naphthol sorption were determined to be ${\sim}3.12$