• Title/Summary/Keyword: 15A

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Polymorphisms of the Exons 13, 15 and 16 of Transferrin Gene in Cheju Horses (제주마 Transferrin Gene Exon 13, 15 및 16의 다형현상)

  • Kim, N.Y.;Lee, S.S.;Yang, Y.H.
    • Journal of Animal Science and Technology
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    • v.44 no.4
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    • pp.391-398
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    • 2002
  • This study was conducted to determine the polymorphism of transferrin exons 13, 15 and 16 by Single-Strand Conformation Polymorphism(SSCP) analysis and to compare their genotypes of Cheju horse Group I (Cheju Institute), Cheju horse Group II (farms), and Thoroughbred (KRA). SSCP of transferrin exon 13, 15, and 16 showed two (A, B), three (A, B, C) and three (A, B, C) codominant alleles, respectively. The Group I and Thoroughbred showed the similar frequencies of allele A and B in transferrin exon 13, but only allele A was observed in Group Ⅱ. In transferrin exons 15 and 16, the frequencies of each allele were different in each Groups. The multiple allele frequencies in exons 15 and 16 suggested that the genotyping of this locus could be used to identify an individual and to test the parentage of offspring. The probability for parentage exclusion were 0.46 and 0.374 for exons 15 and 16 for Cheju horse Group I. Among the 13 combined genotypes of exons 13, 15 and 16, the genotype AA-AB-AB (0.372) is the most common in Cheju horse Group I, but genotype AA-AA-AA is common in the Cheju horse Group II (0.366) and Thoroughbred (0.767). The present study showed two new SNP, which was at the cDNA position 1626 (A/G) in B allele of the exon 13 and 2075 (C/T) in C allele of the exon 16 resulting in amino acid change (Threonine $\longrightarrow$ Methionine). Result showed that polymorphism of exons 13, 15 and 16 in Cheju horses was as high as in Thoroughbred and there was a differences of transferrin allele frequencies in Cheju horses.

Enhanced Segmentized Clear Channel Assessment Method for IEEE 802.15.4 Network (IEEE 802.15.4 Network의 전송효율 향상을 위한 Enhanced Semgentized Clear Channel Assessment 기법)

  • Son, Kyou Jung;Chang, Tae Gyu
    • Journal of IKEEE
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    • v.20 no.3
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    • pp.322-325
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    • 2016
  • This paper proposed Enhanced Segmentized Clear Channel Assesment(ESCCA) for the IEEE 802.15.4 networks. This method divides original CCA into two groups to check precise channel status and perform additional CCA to increase throughput performance. Through the proposed method, the device can access the channel more often, so the transmission efficiency of the IEEE 802.15.4 network improves. To confirm the feasibility and usability of the proposed method, computer simulation has been performed. In the simulation, a star topology with one coordinator and a lot of devices is considered and the traffic flows are all one way, with the communication directed to the coordinator. Simulation results_ show the proposed method is improving maximum 10 kbps of throughput and decreasing maximum 15 of the average number of total CCA than IEEE 802.15.4 CCA method.

15-Hydroxyprostaglandin dehydrogenase as a marker in colon carcinogenesis: analysis of the prostaglandin pathway in human colonic tissue

  • Yang, Dong-Hoon;Ryu, Yeon-Mi;Lee, Sun-Mi;Jeong, Jin-Yong;Yoon, Soon Man;Ye, Byong Duk;Byeon, Jeong-Sik;Yang, Suk-Kyun;Myung, Seung-Jae
    • Intestinal research
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    • v.15 no.1
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    • pp.75-82
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    • 2017
  • Background/Aims: Cyclooxygenase-2 (COX-2), 15-hydroxyprostaglandin dehydrogenase (15-PGDH), and microsomal prostaglandin E synthase-1 (mPGEs-1) regulate prostaglandin $E_2$ ($PGE_2$) expression and are involved in colon carcinogenesis. We investigated the expression of $PGE_2$ and its regulating genes in sporadic human colon tumors and matched normal tissues. Methods: Twenty colonic adenomas and 27 colonic adenocarcinomas were evaluated. COX-2 and 15-PGDH expression was quantified by real-time polymerase chain reaction. The expression of $PGE_2$ and mPGEs-1 was measured using enzyme-linked immunosorbent assay and Western blotting, respectively. Results: The expression of COX-2, mPGEs-1, and $PGE_2$ did not differ between the adenomas and matched distant normal tissues. 15-PGDH expression was lower in adenomas than in the matched normal colonic tissues (P<0.001). In adenocarcinomas, mPGEs-1 and $PGE_2$ expression was significantly higher (P<0.001 and P=0.020, respectively), and COX-2 expression did not differ from that in normal tissues (P=0.207). 15-PGDH expression was significantly lower in the normal colonic mucosa from adenocarcinoma patients than in the normal mucosa from adenoma patients (P=0.018). Conclusions: Early inactivation of 15-PGDH, followed by activation of COX-2 and mPGEs-1, contributes to $PGE_2$ production, leading to colon carcinogenesis. 15-PGDH might be a novel candidate marker for early detection of field defects in colon carcinogenesis.

Quality characteristics of soybean sprouts packaged with different packaging materials during their storage (포장 필름의 종류에 따른 저장 중 콩나물의 품질특성)

  • Hwang, Tae-Young
    • Food Science and Preservation
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    • v.20 no.5
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    • pp.602-607
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    • 2013
  • Correct packaging enables processors to pack fresh produce and extend its shelf life. This study was carried out to investigate the effect of different packaging materials on the weight loss, pH, $O_2$, $CO_2$ and sensory characteristics of soybean sprouts during their storage at $5^{\circ}C$ for seven days. Soybean sprouts ($320{\pm}20g$) were packaged with oriented polypropylene (OPP) and cast polypropylene (CPP) films, respectively. The $O_2$ transmission rate of the packaging materials was set to have a control of $10,000cc/m^2$.day.atm, and an OP15 and CP15 with $15,000cc/m^2$.day.atm through a pre-screening test. The average weight loss of the soybean sprouts during their storage was less than 10%, and that of the soybean sprouts with a CPP film was higher than that of the OPP film. The pH of the soybean sprouts increased during their storage regardless of their packaging materials; but compared to the pH of the soybean sprouts packaged with OPP, those packaged with CPP were higher. The $CO_2$ content of the packaging increased with a decrease in the $O_2$ content. The ratio of $CO_2$ to $O_2$ in the soybean sprouts with the OPP film was 3.5 times higher than in the soybean sprouts with the CPP film. The results of the overall sensory test showed that the marketability of the soybean sprouts packaged with OPP film and stored at $5^{\circ}C$ seemed to have been maintained effectively for six days (at a $15,000cc/m^2$.day.atm $O_2$ transmission rate). When the correlation coefficients of the control, OP15 and CP15 were analyzed, the highest correlation was shown between a control and OP15 (0.986; p<0.01).

Sheet Resistance of Ion Implanted Si(100) at Various Doses, Energies and Beam Currents (Si(100)에 이온 주입 시 에너지, 조사량과 빔 전류에 따른 면저항의 변화)

  • Kim, Hyung-In;Jeong, Young-Wan;Lee, Myeung-Hee;Kang, Suk-Tai
    • Journal of the Korean Vacuum Society
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    • v.20 no.2
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    • pp.100-105
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    • 2011
  • Simulations were performed using Crystal TRIM software under the same conditions used by previous researchers in order to clarify the mechanism that determines sheet resistance various doses, energies and beam currents. The results showed that the peak of the depth profile (Rp) in the same sample gradually shifts inward and damage increases near the surface as the energy increases for $As^+$ equal dose of $1{\times}10^{15}/cm^2$ implanted into Si(100) energies of 5, 10, and 15 keV. From a theoretical calculation of B+ ion implantation processes at energy of 20 keV using parameters that correspond to 1 mA and 7 mA beam currents with the same dose of $5{\times}10^{15}/cm^2$, it was found that the higher beam currents resulted in more damage near the surface (<100 nm). Likewise, In the simulations employing sets of doses ($1{\times}10^{15}$, $3{\times}10^{15}/cm^2$) and beam currents (0.8 mA, 8 mA), more damage was produced at larger doses and higher current. Thus, sheet resistance at the surface was reduced by the intensified damage from increases in beam energy, dose and beam currents.

A Study on the Adsorption Characteristics of Benzene using Activated Carbon from Sewage Sludge (하수슬러지 활성탄의 벤젠 흡착특성)

  • Kim, Jong-Moon;Chung, Chan-Kyo;Lee, Taek-Ryong;Min, Byong-Hun;Kim, Hyung-Jin;Kwon, Young-Shik
    • Clean Technology
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    • v.15 no.4
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    • pp.265-272
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    • 2009
  • In this study the experiments on the static adsorption of benzene were carried out using activated carbon made from sewage sludge. The experiment was performed at 303.15 K, 318.15 K and 333.15 K under the pressure up to 7.999kPa. Isothermal adsorption curves were obtained using Langmuir isotherm, Freundlich isotherm and Toth isotherm for comparison. Based on fitting the adsorption quantity of Benzene (q), the isothermal adsorption curves obtained from Langmuir isotherm and Toth isotherm showed the higher accuracy. Although there was little difference in accuracy between result from Langmuir isotherm and that from Toth isotherm, the adsorption quantity of Benzene (q) was expressed in terms of Langmuir isotherm because less parameters were required for Langmuir isotherm than for Toth isotherm. Moreover SEM images of the activated carbon from sewage sludge and the commercial activated carbon were taken to observe the pore size development. The results showed that the perforation development of the commercial activated carbon (DARCO A.C., SPG-100 A.C.) was better than that of activated carbon from sewage sludge. Adsorption quantity of benzene on commercial activated carbon was confirmed to be higher than that on activated carbon from sewage sludge. However the maximum adsorption quantity of benzene on activated carbon from sewage sludge was close to that on SGP-100 A.C. at 303.15K. Therefore, we may conclude that it is feasible to commercialize the process to manufacturing activated carbon from sewage sludge.

WiMedia-MBOA UWB기반 고속 WPAN

  • 김동호;유지원;성종진
    • TTA Journal
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    • s.100
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    • pp.161-169
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    • 2005
  • IEEE802.15에서 표준화가 진행중인 WPAN(wireless personal network)은 개인영역 네트워크 혹은 근거리 무선 네트워크를 구축하기 위한 기술로, 개인용 컴퓨터, PDA, 주변기기, 휴대전화, 가전 등의 휴대나 이동 컴퓨팅을 위한 기술이다. IEEE802.15.1에서는 블루투스, IEEE802.15.4에서는 ZigBee를 위한 저속 WPAN(low rate WPAN) 그리고 IEEE802.15.3에서는 고속 WPAN(high rate WPAN)에 대한 표준화를 담당하고 있다. 본 고에서는 IEEE802.15 산하 TG3a에서 표준화 중인 Alt-PHY 기술로 경합을 벌이고 있는 MBOA(Multi-Band Orthogonal frequency division multiplexing Alliance) UWB(ultrawideband)에 대한 활성화를 꾀하고 있는 WiMedia Alliance의 시험인증 동향을 고찰하고자 한다.

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Real-Time Transmission Method of Wireless Control Network using IEEE 802.15.4 Protocol (IEEE 802.15.4 기반의 무선 제어 망을 위한 실시간 전송기법에 대한 연구)

  • Lee, Jung-Il;Chol, Dong-Hyuck;Kim, Dong-Sung
    • Proceedings of the KIEE Conference
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    • 2007.04a
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    • pp.178-180
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    • 2007
  • In this paper, a real-time transmission algorithm based on IEEE 802.15.4 is proposed. The superframe of IEEE 802.15.4 is applied to the transmission method of real-time mixed data (periodic data, sporadic data, and non real-time message). The simulation results show the real-time performance of sporadic data is improved by using the proposed transmission algorithm.

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Neighbor Discovery for Peer-to-Peer Communications in the IEEE 802.15.3c (IEEE 802.15.3c에서 Peer-to-Peer 통신을 위한 이웃 발견)

  • Ahn, Sanghyun
    • Proceedings of the Korea Information Processing Society Conference
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    • 2012.11a
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    • pp.848-849
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    • 2012
  • IEEE 802.15.3c 는 IEEE 802.15.3 WPAN 에 mmWave(millimeter wave) 기반 물리 계층의 표준화를 하는 것을 목적으로 하며, 사용 대역의 특성상 지향성(directional) 안테나를 이용해서 통신을 한다. 또한 하나의 노드를 중심으로 피코넷을 형성하고 그 피코넷 내에서 peer 노드들 간 직접 통신을 위해서 peer 노드를 발견하는 효율적인 기법이 요구된다. 본 논문에서는 지향성 안테나를 사용하는 IEEE 802.15.3c 의 특성을 고려한 효율적인 이웃 발견 기법을 제안한다.

The study on the scattering ratio at the edge of the block according to the increasing block thickness in electron therapy (전자선 치료 시 차폐블록 두께 변화에 따른 블록 주변 선량에 관한 연구)

  • Park, Zi On;Gwak, Geun Tak;Park, Ju Kyeong;Lee, Seung Hun;Kim, Yang Su;Kim, Jung Soo;Kwon, Hyoung Cheol;Lee, Sun Young
    • The Journal of Korean Society for Radiation Therapy
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    • v.31 no.1
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    • pp.57-65
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    • 2019
  • Purpose: The purpose is to clarify the effect of additional scattering ratio on the edge of the block according to the increasing block thickness with low melting point lead alloy and pure lead in electron beam therapy. Methods and materials: $10{\times}10cm^2$ Shielding blocks made of low melting point lead alloy and pure lead were fabricated to shield mold frame half of applicator. Block thickness was 3, 5, 10, 15, 20 (mm) for each material. The common irradiation conditions were set at 6 MeV energy, 300 MU / Min dose rate, gantry angle of $0^{\circ}$, and dose of 100 MU. The relative scattering ratio with increasing block thickness was measured with a parallel plate type ion chamber(Exradin P11) and phantom(RW3) by varying the position of the shielding block(cone and on the phantom), the position of the measuring point(surface ans depth of $D_{max}$), and the block material(lead alloy and pure lead). Results : When (depth of measurement / block position / block material) was (surface / applicator / pure lead), the relative value(scattering ratio) was 15.33 nC(+0.33 %), 15.28 nC(0 %), 15.08 nC(-1.31 %), 15.05 nC(-1.51 %), 15.07 nC(-1.37 %) as the block thickness increased in order of 3, 5, 10, 15, 20 (mm) respectively. When it was (surface / applicator / alloy lead), the relative value(scattering ratio) was 15.19 nC(-0.59 %), 15.25 nC(-0.20 %), 15.15 nC(-0.85 %), 14.96 nC(-2.09 %), 15.15 nC(-0.85 %) respectively. When it was (surface / phantom / pure lead), the relative value(scattering ratio) was 15.62 nC(+2.23 %), 15.59 nC(+2.03 %), 15.53 nC(+1.67 %), 15.48 nC(+1.31 %), 15.34 nC(+0.39 %) respectively. When it was (surface / phantom / alloy lead), the relative value(scattering ratio) was 15.56 nC(+1.83 %), 15.55 nC(+1.77 %), 15.51 nC(+1.51 %), 15.42 nC(+0.92 %), 15.39 nC(+0.72 %) respectively. When it was (depth of $D_{max}$ / applicator / pure lead), the relative value(scattering ratio) was 16.70 nC(-10.87 %), 16.84 nC(-10.12 %), 16.72 nC(-10.78 %), 16.88 nC(-9.93 %), 16.90 nC(-9.82 %) respectively. When it was (depth of $D_{max}$ / applicator / alloy lead), the relative value(scattering ratio) was 16.83 nC(-10.19 %), 17.12 nC(-8.64 %), 16.89 nC(-9.87 %), 16.77 nC(-10.51 %), 16.52 nC(-11.85 %) respectively. When it was (depth of $D_{max}$ / phantom / pure lead), the relative value(scattering ratio) was 17.41 nC(-7.10 %), 17.45 nC(-6.88 %), 17.34 nC(-7.47 %), 17.42 nC(-7.04 %), 17.25 nC(-7.95 %) respectively. When it was (depth of $D_{max}$ / phantom / alloy lead), the relative value(scattering ratio) was 17.45 nC(-6.88 %), 17.44 nC(-6.94 %), 17.47 nC(-6.78 %), 17.43 nC(-6.99 %), 17.35 nC(-7.42 %) respectively. Conclusions: When performing electron therapy using a shielding block, the block position should be inserted applicator rather than the patient's body surface. The block thickness should be made to the minimum appropriate shielding thickness of each corresponding using energy. Also it is useful that the treatment should be performed considering the influence of scattering dose varying with distance from the edge of block.