• Title/Summary/Keyword: 15A

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Septo-optic dysplasia associated with chromosome 15q13.3 duplication: a case report

  • Jeong A Ham;Sung Hyun Kim;Donghwi Park
    • Journal of Yeungnam Medical Science
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    • v.40 no.4
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    • pp.419-422
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    • 2023
  • Septo-optic dysplasia (SOD) is a rare congenital anomaly that is clinically defined by developmental delay and characteristic brain magnetic resonance imaging findings, including optic nerve hypoplasia, pituitary hormone abnormalities, and midline brain defects. The occurrence of SOD is generally sporadic; however, it can be inherited rarely. Although an association with HESX1, SOX2, and SOX3 mutations has been identified, the detailed etiology is multifactorial and unclear. Here, we present the case of a 7-year-old girl who was clinically diagnosed with SOD and 15q13.3 duplication. Patients with duplication at chromosome 15q13.3 were reported to be diagnosed with autism spectrum disorder, epilepsy, and schizophrenia in previous studies. The relationship between SOD and the microduplication of 15q13.3 has not yet been explored. In this study, we suggest that there may be an association between chromosome 15q13.3 microduplication and SOD.

PB-Overexpression of OsZn15, a CCCH-tandem zinc finger protein, increases drought tolerance in rice

  • Seong, So Yoon;Jung, Harin;Choi, Yang Do;Kim, Ju-Kon
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.115-115
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    • 2017
  • Zinc finger proteins constitute a large family which has been studied to have various functions in different organisms. Tandem CCCH zinc finger proteins (TZFs), members of the zinc finger protein family, are known to participate as post-transcriptional regulators of gene expression in eukaryotes. Here, we showed that the OsZn15, a gene for tandem CCCH zinc finger protein, is induced by abiotic stress and its overexpression in transgenic rice plants (PGD1:OsZn15) gains higher drought tolerance. Gene expression analysis of promoter:GFP plants revealed that OsZn15 is specifically expressed in anther and embryo, but not in vegetative organs. In-field evaluation, grain yield was higher in the PGD1:OsZn15 than nontransgenic plants under drought conditions. Interestingly, OsZn15 is shown to not only localize at nucleus but also co-localize with both processing bodies (PB) and stress granules (SG), two messenger ribo-nucleoprotein complexes which are known to activate by forming cytoplasmic foci under stress conditions. In sum, these results suggest that OsZn15 increases drought stress tolerance of rice probably by participating in RNA turnover in PB and SG.

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UBV I CCD PHOTOMETRY OF THE OPEN CLUSTERS NGC 4609 AND HOGG 15

  • Kook, Seung-Hwa;Sung, Hwan-Kyung;Bessell, M.S.
    • Journal of The Korean Astronomical Society
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    • v.43 no.5
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    • pp.141-152
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    • 2010
  • UBV I CCD photometry is obtained for the open clusters NGC 4609 and Hogg 15 in Crux. For NGC 4609, CCD data are presented for the first time. From new photometry we derive the reddening, distance modulus and age of each cluster - NGC 4609 : E(B-V ) = $0.37{\pm}0.03$, $V_0-M_V=10.60{\pm}0.08$, log $\tau$= 7.7 $\pm$ 0.1; Hogg 15 : E(B - V ) = 1.13 $\pm$ 0.11, $V_0-M_V$ = 12.50 $\pm$ 0.15, log $\tau$ $\lesssim$ 6.6. The young age of Hogg 15 strongly implies that WR 47 is a member of the cluster. We also determine the mass function of these clusters and obtain a slope $\Gamma$ = -1.2 ($\pm$0.3) for NGC 4609 which is normal and a somewhat shallow slope (${\Gamma}=-0.95{\pm}0.5$) for Hogg 15.

Scheduling Scheme and Performance Analysis of IEEE802.15.4e TSCH (IEEE802.15.4e TSCH의 스케줄링 방식 및 성능분석)

  • Park, Mi-Ryong;Kim, Dongwon
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.17 no.5
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    • pp.43-49
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    • 2017
  • In this paper, we propose the scheduling scheme of IEEE802.15.4e TSCH which is not specified in standard specification. The proposed scheme schedules the link by cooperating among the devices. A new device scans EBs(Enhanced Beacons) from network. An advertiser device broadcasts an enhanced beacon frame including links information on allocated channel offset and time-slots, and a new device can determine its own channel offset and time-slot. It's performance on maximum throughput and minimum delay is evaluated by comparing the proposed approach with a typical single channel IEEE802.15.4.

Broadcasting Message Reduction Methods in VANET

  • Makhmadiyarov, Davron;Hur, Soojung;Park, Yongwan
    • IEMEK Journal of Embedded Systems and Applications
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    • v.4 no.1
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    • pp.42-49
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    • 2009
  • Most Vehicular Ad hoc Network (VANET) applications rely heavily on broadcast transmission of traffic related information to all reachable nodes within a certain geographical area. Among various broadcast approaches, flooding is the first broadcasting technique. Each node rebroadcasts the received message exactly once, which results in broadcast storm problems. Some mechanisms have been proposed to improve flooding in Mobile Ad hoc Networks (MANET), but they are not effective for VANET and only a few studies have addressed this issue. We propose two distance-based and timer-based broadcast suppression techniques: 15P(15percent) and slotted 15P. In the first (distance based) scheme, node's transmission range is divided into three ranges (80%,15%and5%). Only nodes within 15% range will rebroadcast received packet. Specific packet retransmission range (15%) is introduced to reduce the number of messages reforwarding nodes that will mitigate the broadcaststorm. In the second (timer-based) scheme, waiting time allocation for nodes within 15% range isused to significantly reduce the broadcaststorm. The proposed schemes are distributed and reliedon GPS information and do not requireany other prior knowledge about network topology. To analyze the performance of proposed schemes, statistics such as link load and the number of retransmitted nodes are presented. Our simulation results show that the proposed schemes can significantly reduce link load at high node densities up to 90 percent compared to a simple broadcast flooding technique.

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Stable Nitrogen Isotopes in a Forested Watershed in Taiwan

  • Owen, Jeffrey S.
    • Journal of Forest and Environmental Science
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    • v.29 no.2
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    • pp.116-124
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    • 2013
  • Differences in rates and patterns of nitrogen cycling have been correlated with nitrogen stable isotope measurements in forest ecosystems of tropical and temperate regions, but limited similar work has been conducted in sub-tropical forests. This study investigated patterns in stable N isotopic composition in a subtropical forest in Taiwan by sampling three soil profiles and overstory and understory foliage. Soil ${\delta}^{15}N$ in the forest floor ranged from -1.8 to -1.8‰. Mineral soils had higher ${\delta}^{15}N$ (4.1 to 6.0‰). Foliage ${\delta}^{15}N$ in overstory trees ranged from -6.6 to -2.0‰, and understory foliage ${\delta}^{15}N$ ranged from -5.0 to -1.2‰. There was a weak correlation between foliar % N and ${\delta}^{15}N$ ($r^2=0.214$). Compared to results from similar surveys in tropical and temperate forests, foliar ${\delta}^{15}N$ values were generally lower. These results help highlight the need for improved knowledge regarding the relationships between patterns in N stable isotopes and processes affecting rates of N cycling, especially as related to wider scale patterns in forest ecosystems within the east-Asia region.

Implementation and Performance Evaluation of Digital Flickermeter Algorithm According to IEC61000-4-15 Edition 2 for Korean Distribution Power System (국내 계통 특성을 고려한 IEC61000-4-15 Edition 2 기반의 디지털 플리커 미터 알고리즘 구현 및 평가)

  • Shin, Hoon-Chul;Han, Su-Kyoung;Park, Sang-Ho;Kim, Kern-Joong;Cho, Soo-Hwan
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.66 no.7
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    • pp.1017-1024
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    • 2017
  • The International Electrotechnical Commission(IEC) 61000-4-15 is a standard proposing techniques for a flicker meter test and measurement method. The IEC61000-4-15 ed1 announced in 1997 was not include tests for accurate verification. Also it was not explained flicker meter algorithm that can be directly applied to the other power systems. But the new edition of IEC61000-4-15 ed2 prescribes a variety of tests for verify flicker meter algorithm and it explains 'correction factor' used for measuring flicker in other power systems. It can measure flicker severity in 220V system by multiplying correction factor to the measured values with the 230V algorithm. This paper compared the method of measuring flicker severity in korea power system using the correction factor and the modified weighting filter, after verifying of digital flicker meter algorithm created by using matlab based on IEC61000-4-15 ed2.

Rare-Earth Metal Complex-Functionalized Mesoporous Silica for a Potential UV Sensor (잠재적인 UV 센서를 위한 희토류 금속착물이 기능화된 메조다공성 실리카)

  • Sung Soo Park;Mi-Ra Kim;Weontae Oh;Yedam Kim;Yeeun Lee;Youngeon Lee;Kangbeom Ha;Dojun Jung
    • Journal of Adhesion and Interface
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    • v.24 no.4
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    • pp.136-142
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    • 2023
  • In this study, TEOS was used as a silica source, and a triblock copolymer (P123) was used as a template to produce mesoporous silica with a well-ordered hexagonal mesopore array through a self-assembly method and hydrothermal process under acidic condition. (Surfactant-extracted SBA-15). Surfactant-extracted SBA-15 showed the particle shape of a short rod with a size of approximately 980 nm. The surface area and pore diameter were 730 m2g-1 and 70.8 Å, respectively. Meanwhile, aminosilane (3-aminopropyltriethoxysilane, APTES) was grafted into the mesopores using a post-synthesis method. Mesoporous silica (APTES-SBA-15) modified with aminosilane had a well-ordered pore structure (p6mm) and well-maintained the particle shape of short rods. The surface area and pore diameter of APTES-SBA-15 decreased to 350 m2g-1 and 60.7 Å, respectively. APTES-modified mesoporous silica was treated with a solution of rare earth metal ions (Eu3+, Tb3+) to synthesize a mesoporous silica material in which rare earth metal complexes were introduced into the mesopores. (Eu/APTES-SBA-15, Tb/APTES-SBA-15) These materials exhibited characteristic photoluminescence spectra by λex=250 nm. (5D47F5 (543.5 nm), 5D47F4 (583.5 nm), 5D47F3 (620.2 nm) transitions for Tb/APTES-SBA-15; 5D07F0 (577.7 nm), 5D07F1 (592.0 nm), 5D07F2 (614.9 nm), 5D07F3 (650.3 nm) and 5D07F4 (698.5 nm) transitions for Eu/APTES-SBA-15)

Effect of Feeding Date Pits on Milk Production, Composition and Blood Parameters of Lactating Ardi Goats

  • AL-Suwaiegh, S.B.
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.4
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    • pp.509-515
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    • 2016
  • Twenty Ardi lactating goats were used to investigate the effect of substituting 10%, 15%, and 20% of concentrate feed with date pits on milk production, composition, and blood parameters. Four isocaloric and isonitrogenous dietary treatments were used. Four levels (0% [control], 10%, 15%, and 20%) of date pits were used to replace concentrate feed. The forages to concentrate ratio used was 60 to 40. Dry matter intake (DMI) of goats fed diets containing 10% and 15% date pits was significantly (p<0.05) higher than those fed diets containing 0% and 20%. However, goats fed a diet containing 20% date pits were significantly (p<0.05) lower in DMI compared to those fed control diet. The protein percent was significantly higher for goats fed control diet compared to the other dietary treatments. Total solids percent was significantly the lowest for goats fed diet supplemented with 10% date pits. Goats fed a diet containing 20% date pits was significantly (p<0.05) higher in the total protein compared to those fed a diet containing 10%. In addition, goats fed a diet containing 15% date pits exhibited no significant differences in the total protein percent compared to those fed a diet containing 20% date pits. Triglyceride was significantly higher for goats fed diets containing 10% and 20% date pits compared to those fed 15% date pits. Results obtained in the present study suggest that date pits can be added up to 20% of the concentrate feeds into lactating Ardi goat diets without negative effects on their productive performance.

Generation of mmp15b Zebrafish Mutant to Investigate Liver Diseases

  • Kim, Oc-Hee;An, Hye Suck;Choi, Tae-Young
    • Development and Reproduction
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    • v.23 no.4
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    • pp.385-390
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    • 2019
  • Upon gene inactivation in animal models, the zebrafish (Danio rerio) has become a useful model organism for many reasons, including the fact that it is amenable to various forms of genetic manipulation. Genome editing is a type of genetic engineering in which DNA is inserted, deleted, modified, or replaced in the genome of a living organism. Mainly, CRISPR (clustered regularly interspaced short palindromic repeats) Cas9 (CRISPR-associated protein 9) is a technology that enables geneticists to edit parts of the genome. In this study, we utilized this technology to generate an mmp15b mutant by using zebrafish as an animal model. MMP15 is the membrane-type MMP (MT-MMP) which is a recently identified matrix metalloproteinase (MMP) capable of degrading all kinds of extracellular matrix proteins as well as numerous bioactive molecules. Although the newly-established mmp15b zebrafish mutant didn't exhibit morphological phenotypes in the developing embryos, it might be further utilized to understand the role of MMP15 in liver-related diseases, such as liver fibrosis, and associated pathogeneses in humans.