• Title/Summary/Keyword: 14-3-3

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The Sterol Components of Undaria Pinnatifida and the Incorporation of $^14C-1-acetate$ into Them (미역의 스테롤 조성과 $^14C-1$-식초산염의 스테롤 전환에 관하여)

  • JOH Yong-Goe;HATA Mitsuo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.10 no.3
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    • pp.163-170
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    • 1977
  • The present study was carried out to knew the sterol components of U. pinnatifida and their incorporation abilities of $^14C-1-acetate$ injected into it. The results obtained are as follows: 1. The total lipids are classified as hydrocarbon $1.6\%$, pigment and sterol ester $2.5\%$, triglyceri do $3.3\%$, free fatty acid $2.2\%$, free sterol $3.8\%$, chlorophyll $18.8\%$, and polar lipids $ 67.3\%$ 2. The sterol mixture from U. pinnatifida are omposed of cholesterol $3.5\%$, 24-methylene-cholesterol $11.2\%$, fucosterol $85.3\%$. 3. The radioactivities of the lipids classes from U. pinnatifida injected with $^14C-1-acetate$ are distributed 4,648 dpm/ug in total lipid, 2,754 dpm/mg in polar lipids, 373 dpm/mg in chlorophyll, 22,481 dpm/mg in free sterol, 6,520 dpm/mg in free fatty acid, 789 dpm/mg in sterol ester and 358 dpm/mg in hydrocarbon respectively. 4. The specific radioactivities of the sterols are 115 dpm/mg in cholesterol, 147,821 dpm/mg in 24-methylenecholesterol, 20, 887 dpm/mg in fucosterol.

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Corrosion Behaviour of Fe-XAl-0.3Y Alloys at High Temperature Sulfidation Environment(Ps2=10-3Pa) (Fe-XAl-0.3Y 합금의 고온 황화환경(Ps2=10-3Pa)에서의 부식거동)

  • Lee Byung Woo;Park Hwa Soon
    • Korean Journal of Materials Research
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    • v.14 no.8
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    • pp.547-551
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    • 2004
  • The sulfidation behaviour of Fe-XAl-0.3Y(X=5, 10, 14, 25 $wt.\%$) alloys was investigated at 1123 K in $H_2/H_{2}S$ gas atmosphere for $1\sim24$ hrs using SEM/EDX, XRD and EPMA. The weight changes of Fe-XAl-0.3Y alloys followed the parabolic rate law, Sulfidation rates of iron aluminide alloys with high Al content were one-twentieth lower than that of 5Al alloys. This is due to the formation of protective $Al_{2}O_3$ oxides on the surface of 10Al, 14Al and 25Al alloys. By calculating partial pressure of impurity oxygen contained $H_2/H_{2}S$ gas, the $Al_{2}O_3$ oxides formation could be explained using Fe-Al-S-O thermodynamic stability diagram. The sulfidation product scales of the 5Al alloy showed that thick iron sulfide scale(FeS) containing porosities formed during early stages of sulfidation. With continued sulfidation, aluminum sulfide was formed at the alloy/scale interface.

Crystal chemistry and growth of$La_3Ga_5SiO_{14}$ for the applications of filter and resonator (필터와 레죠네이터 응용을 위한 $La_3Ga_5SiO_{14}$ 의 결정화학 및 성장)

  • Jung, Il-Hyoung;Joo, Kyung;Shim, Kwang-Bo;Auh, Keun-Ho
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.9 no.1
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    • pp.74-79
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    • 1999
  • Langasite($La_3Ga_5SiO_14$) is a new piezoelectric material which is similar to quartz, LN($LiNbO_3$) and LT($LiTaO_3$) in its acoustic behavior. In this study, pure Langasite and Lagnasite family groups were synthesized by the solid state reactions in air. The diffusion species for synthesis were investigated and the sintered body was studied on dielectric property to comparison of characteristics. Also, Langasite single crystals were grown by self-designed Czochralski system and characterized.

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HSV-1 ICP27 induces apoptosis by promoting Bax translocation to mitochondria through interacting with 14-3-3θ

  • Kim, Ji Ae;Kim, Jin Chul;Min, Jung Sun;Kang, Inho;Oh, Jeongho;Ahn, Jeong Keun
    • BMB Reports
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    • v.50 no.5
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    • pp.257-262
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    • 2017
  • The subcellular localization of Bax plays a crucial role during apoptosis. In response to apoptotic stimuli, Bax translocates from the cytoplasm to the mitochondria, where it promotes the release of cytochrome c to the cytoplasm. In cells infected with HSV-1, apoptosis is triggered or blocked by diverse mechanisms. In this study, we demonstrate how HSV-1 ICP27 induces apoptosis and modulates mitochondrial membrane potential in HEK 293T cells. We found that ICP27 interacts with $14-3-3{\theta}$ which sequesters Bax to the cytoplasm. In addition, ICP27 promotes the translocation of Bax to the mitochondria by inhibiting the interaction between $14-3-3{\theta}$ and Bax. Our findings may provide a novel apoptotic regulatory pathway induced by ICP27 during HSV-1 infection.

Effect of CNT Addition on the Hydriding and Dehydriding Rates of Mg-Ni-Fe2O3 Alloy

  • Song, Myoung Youp;Kwak, Young Jun;Lee, Byung-Soo;Park, Hye Ryoung;Kim, Byoung-Goan
    • Korean Journal of Metals and Materials
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    • v.49 no.12
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    • pp.989-994
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    • 2011
  • Samples with compositions of 80 wt% Mg-14 wt% Ni-6 wt% $Fe_2O_3$ (named $Mg-Ni-Fe_2O_3$), and 78 wt% Mg-14 wt% Ni-6 wt% $Fe_2O_3-2$ wt% CNT (named $Mg-Ni-Fe_2O_3-CNT$ ) were prepared by reactive mechanical grinding. Hydriding and dehydriding properties and effects of CNT addition on the hydriding and dehydriding rates of $Mg-Ni-Fe_2O_3$ were then investigated. Activation of the $Mg-14Ni-6Fe_2O_3$ sample was completed after three hydriding (under 12 bar $H_2$)-dehydriding (under 1.0 bar $H_2$) cycles at 573 K. The addition of CNT to the $Mg-14Ni-6Fe_2O_3$ sample made the activation process unnecessary, with a small decrease in the hydrogen-storage capacity.

Annual Equilibrium Moisture Content of Wood in Korea (한국(韓國)의 목재평형함수율(木材平衡含水率))

  • Jo, Jae-Myeeng;Kang, Sun-Goo;Shim, Chong-Supp;Jung, Hee-Suk
    • Journal of the Korean Wood Science and Technology
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    • v.10 no.2
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    • pp.3-11
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    • 1982
  • In order to investigate the annual mean equilibrium moisture content(EMC), the equilibrium moisture content investigated were the desorbed and adsorbed equilibrium moisture content with two end-matched samples for red pine (Pinus densiflora S. et Z.), Douglas fir (Pseadotsuga menziesii Franco), oak (Quercus mongolica Fischer) and red lauan (Shorea spp.) in instrument screen at forest experiment station located in Seoul, Chuncheon, Daejeon, Kyungju, Jinju and Gwangju area for four years (1970. 1 - 1973. 12). The results summarized were as follows. 1. The annual mean desorbed equilibrium moisture content of red pine, Douglar fir, oak and red lauan were 14.8, 13.7, 14.0 and 14.2 percent respectively and higher than the annual mean adsorbed equilibrium moisture content of those species. 2. The annual mean desorbed - and adsorbed equilibrium moisture content in central areas (Seoul, Chuncheon, Daejeon) were higher than those in southern areas (Kyungju, Jinju, Gwangju). 3. On the whole, the monthly mean desorbed - and adsorbed equilibrium moisture content were lowest in April and highest in August though difference of month in areas. 4. Average and range of annual national equilibrium moisture content was 12.3 ~ 14.2 ~ 15.7 percent for desorbed equilibrium moisture content and 11.3 ~ 13.2 ~ 14.7 percent for adsorbed equilibrium moisture content and 12.0 ~ 14.1 ~ 16.4 percent for calculated equilibrium moisture content based on tempera ture and humidity.

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Annual Equilibrium Moisture Content of Wood in Korea (한국(韓國)의 목재평형함수율(木材平衡含水率))

  • Jo, Jae-Myeong;Kang, Sun-Goo;Shim, Chong-Supp;Jung, Hee-Suk
    • Journal of the Korean Wood Science and Technology
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    • v.10 no.3
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    • pp.109-117
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    • 1982
  • In order to investigate the annual mean equilibrium moisture content (EMC), the equilibrium moisture content investigated were the desorbed - and adsorbed equilibrium moisture content with two end-matched samples for red pine (Pinus densiflora S. et Z.), Douglas fir (Pseadotsuga menziesii Franco), oak (Quercus mongolica Fischer) and red lauan (Shorea spp.) in instrument screen at forest experiment station located in Seoul, Chuncheon, Daejeon, Kyungju, Jinju and Gwangju area for four years (1970. 1 - 1973. 12). The results summarized were as follows. 1. The annual mean desorbed equilibrium moisture content of red pine, Douglar fir, oak and red lauan were 14.8, 13.7, 14.0 and 14.2 percent respectively and higher than the annual mean adsorbed equilibrium moisture content of those species. 2. The annual mean desorbed - and adsorbed equilibrium moisture content in central areas (Seoul, Chuncheon, Daejeon) were higher than those in southern areas (Kyungju, Jinju, Gwangju). 3. On the whole, the monthly mean desorbed - and adsorbed equilibrium moisture content were lowest in April and highest in August though difference of month in areas. 4. Average and range of annual national equilibrium moisture content was 12.3 ~ 14.2 ~ 15.7 percent for desorbed equilibrium moisture content and 11.3 ~ 13.2 ~ 14.7 percent for adsorbed equilibrium moisture content and 12.0 ~ 14.1 ~ 16.4 percent for calculated equilibrium moisture content based on tempera.

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Influence of Stage of Maturation of Bovine Oocytes at Time of Vitrification on In Vitro Development and Viability (한우 미성숙 난자의 체외성숙 단계가 Vitrification 동결시 체외발생 및 생존성에 미치는 영향에 관한 연구)

  • 김상근;신현주
    • Journal of Embryo Transfer
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    • v.17 no.1
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    • pp.61-65
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    • 2002
  • This study was carried out to study the viability of oocytes when vitrified at various maturation stages. Bovine cumulus-oocyte complexes were recovered from ovaries at a slaughter and then divided into five groups: control group(unvitrified oocytes), 0 hr. group(composed of oocytes vitrified before the onset of maturation) and 10, 14, and 20 hrs groups(vitrified at 10, 14 and 20 hrs after the onset of maturation, respectively). The oocytes remained vitrified for 24 hrs, and then were thawed in 3$0^{\circ}C$. Survival and cleavage rates were investigated by results of in vitro culture and aceto-orcein staining or FDA test. No difference in the incidence of diploid oocytes was observed among the control, non-vitrified group(3.6%) and oocytes vitrified at 14 hrs(6.7%) or 20 hrs(1.7%). However, more diploid oocytes were detected after vitrification at 0 hr.(26.7%) and 10 hrs(21.7%) post maturation. The survival rate of all vitrified immature oocytes(12.0~38.0%) was low, 48.0% of unvitrified oocytes and oocytes vitrified before maturation or 0~ 10 hrs after the onset of maturation were higher than that of other groups. The overall fertilization and cleavage rates of vitrified immature oocytes (32.3 ~ 64.6% and 4.6 ~ 32.3%) were low, and 55.0% of unvitrified oocytes and the rate of immature oocytes were very higher than that of mature oocytes.

The Synthesis of 6-[1-(4-Ribitylanilino)ethyl]-1,3-dimethyllumazine Related to Methanopterin (Methanopterin과 관련된 6-[1-(4-Ribitylanilino)ethyl]-1,3,7-trimethyllumazine의 합성)

  • Jang, Yong Jin;Kim, Yeon Hee;Kang, Yong Han
    • Journal of the Korean Chemical Society
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    • v.43 no.6
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    • pp.670-675
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    • 1999
  • 6-[1-(4-Ribitylanilino)ethyl]-1,3,7-trimethyllumazine (2), which is related to pteridine moiety of methanopterin, was synthesized. 4-Ribitylaniline derivative was prepared from D-ribose and N-benzoyl-4-bromoaniline (7) as the starting materials through several steps. 6-Acetyl-1,3,7-trimethyllumazine (4) was obtained from the reaction of 4-amino-1,3-dimethyI-5-nitrosouracil (3) with 2,4-pentanedione by Timmis reaction. Compound 4 was converted to 6-(1-chloroethyl)-1,3,7-trimethyllumazin (6) by the reduction with sodium borohydride and followed by chlorination with thionyl chloride. The nucleophilic displacement reaction of compound 6 with 4-(2,3:4,5-di-O-iso-propylidene-D-ribityl)aniline (13) in anhydrous DMF yielded 6-[1-{4-(2,3:4,5-di-O-isopropylidene-D-ribityl)anilino}ethyl]-1,3,7-trimethyllumazine (14). The target molecule 2 was obtained by the hydrolysis of compound 14 in the presence of an acid catalyst.

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