• 한국실내디자인학회논문집
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• 제25권2호
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• pp.59-69
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• 2016

This study aimed to understand the importance of applying finishing materials into interior space, and to add meaning to the creation of functional space, associated interior finishing materials with brain science. To achieve this purpose, brainwave(EEG) experiment was conducted. The brainwave appearing when sensing the surface of interior finishing materials with hands was measured. The locations of the electrode were FP1, FP2, F3, F4, C3, C4, P3, P4, O1, O2, F7, F8, T3, T4, T5, T6, CZ, FZ, and PZ and in addition to these, AFZ was added. Eight(8) kinds of finishing materials: metallic material, film paper, lumbar, stone, glass, silk wallpaper, fabric, and paint were used to measure '${\alpha}$-wave against ${\beta}$ wave.' As a result, it was found that the most activated finishing material in term of relaxation was film paper, followed by metallic, glass, paint, fabric, stone, lumbar, and silk wallpaper. To explain in light of this, (1) '${\alpha}$-wave against ${\beta}$ wave' was the most activated at ch1-FP1 and ch2-FP2, and at ch17-AFZ and ch19-FZ, which indicated that metopic-prefrontal lobe showed the highest activation in relaxation. Film paper, among the finishing materials, showed the highest increase in relaxation. (2) In general, '${\alpha}$-wave against ${\beta}$ wave' relaxation was inhibited at ch13-T3 and ch14-T4, and at ch15-T5 and ch16-T6 and the arousal in the temporal lobe was prominent. Silk wallpaper, among the finishing materials, showed the highest arounsal effect. As a result of measuring the superficial touch on the silk wallpaper, which was regarded as the most rough material among the eight finishing materials, the arousal effect of ${\alpha}$-wave against ${\beta}$-wave, among the brainwave characteristics, was found to be the highest. (3) to judge from the scope of this experiment regarding the tactile sensation over the finishing materials, it is considered that the brainwave reaction sometimes appeared contrastive depending on whether the surface was smooth or rough and there also appeared a difference in relaxation and arousal reaction of the brainwave depending on whether the surface was hot or cold, but the sensation on the surface texture was often evaluated differently depending on who you were. For this reason, this study has some limitations.

• Natural Product Sciences
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• 제25권2호
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• pp.115-121
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• 2019

Alzheimer's disease is a chronic neurodegenerative disorder with no curative treatment. The commercially available drugs, which target acetylcholinesterase, are not satisfactory. The aim of this study was to investigate the cholinesterase inhibitory activity of Solenostemma argel aerial part. Eight compounds were isolated and identified by NMR: kaempferol-3-O-glucopyranoside (1), kaempferol (2), kaempferol-3-glucopyranosyl($1{\rightarrow}6$)rhamnopyranose (3) p-hydroxybenzoic acid (4), dehydrovomifoliol (5), 14,15-dihydroxypregn-4-ene-3,20-dione (6), 14,15-dihydroxy-pregn-4-ene-3,20-dione-$15{\beta}$-D-glucopyranoside (7) and solargin I (8). Two of them (compounds 2 and 3) could inhibit over 50 % of butyrylcholinesterase activity at $100{\mu}M$. Compound (2) displayed the highest inhibitory effect against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with a slight selectivity towards the latter. Molecular docking studies supported the in vitro results and revealed that (2) had made several hydrogen and ${\pi}-{\pi}$ stacking interactions which could explain the compound potency to inhibit AChE and BChE.

• 미생물학회지
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• 제35권1호
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• pp.35-40
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• 1999

소양호에서 식물 플랑크톤이 분비하는 유기물의 분자량 크이게 따른 세균수와 활성의 변화를 측정하였다. 소양호 상걸리 유역에서 여름철에 채수한 물을 tangential flow ultrafiltration 으로 용존 유기물질을 100,000 nMW~0.1$\mu\textrm{m}$, 10,000 nMW~100,000 nMW와 1,000 nMW~10000 nMW의 3개 fraction으로 구분하였고, 여기에 호숫물을 접종하여, 세균수와 $\beta$-glucosidase 의 변화를 측정하였다. 배양기간 동안에 나타난 총세균수는 24시간까지 급격히 증가한 후 점차 안정적으로 변하는 전형적인 성장곡선을 나타내었으며, DOC 농도와 종류가 달랐음에도 , $1.2{\times}10^{7}$ cells $ml^(-1)$범위였고, 저분자 fraction에 비해 최고 1,000배 이상 높았다. 즉 10,000 nMW 이상의 고분자 용존 유기물질은 $\beta$-glucosidase의 유도체로 작용하며, 저분자 용존 유기물질은 $\beta$-glucosidase 활성도를 높이지 못하는 것으로 확인되었다.

• Restorative Dentistry and Endodontics
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• 제14권2호
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• pp.77-97
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• 1989

The purpose of this study was to observe the effect of ${\beta}GP$ in the remaining dental pulp tissue after pulpotomy in the dogs' teeth. For vital pulpotomy, 72 dogs' teeth were used and class V cavities were prepared and the pulps were amputated. ZOE and Dycal (Caulk Co., USA) were placed over the amputated tissue and cavities were sealed with ZOE cement in the control group. In the experimental group, ${\beta}GP$, ${\beta}GP$-ZOE, ${\beta}GP$-Dycal were placed over the exposed pulp tissues respectively. Dogs were sacrificed after 1, 2 and 4 weeks following the operations and the teeth were decalcified in the nitric acid, sectioned and stained with HE for light microscopic examination. For electron microscopic examination, specimens were made after 2 and 4 weeks following the operation. A comparative microscopic examination revealed as follows. 1. The dentin bridge was formed continuously due to osteodentin in the ${\beta}GP$-Dycal group at the 2nd week, the dentin bridge composed of osteodentin and tubular dentin was observed at the 4th week. 2. Osteodentin formation was vigorously in the ${\beta}GP$-Dycal than in the Dycal group. 3. In the surface of osteodentin the osteodentinoblasts showing vivid synthetic activity were observed and the matrix vesicles were presented during calcification of osteoid dentin matrix. 4. The dentin bridge formation was not observed in ${\beta}GP$ group and ${\beta}GP$-ZOE group.

• 대한화학회지
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• 제16권1호
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• pp.6-12
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• 1972

The crystal structure of monoethanolamine hydrochloride is triclinic P1 with two formula units in a cell of dimensions a = $4.42\pm0.02$, b = $7.44\pm0.02$, c = $7.48\pm0.02$, $\alpha$ = $102.4\pm0.3$, $\beta$ = $91.1\pm0.3$, $\gamma$ = $77.2\pm0.3^{\circ}.$ The configuration of monoethanolamine is a gauche form with dihedral angle, $90^{\circ}$. The nitrogen atom forms four hydrogen bonds, three to Cl- ions(3.15, 3.24, $3.28\AA)$ and one to a hydroxyl group of another molecule (N${\cdot}{\cdot}{\cdot}$O, $2.90{\AA})$. The oxygen also forms two such bonds, one to a Cl- ion $(3.14\AA)$, one to an amine group of another molecule (O${\cdot}{\cdot}{\cdot}$N, $2.90{\AA}).$ Molecules are linked into two-dimensional network by hydrogen bonds.

• 약학회지
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• 제43권3호
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• pp.306-315
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• 1999

To develop new cephalosporin antibiotics with improved antibacterial activities, a series of 7$\beta$-[2-(2-aminothiazol-4-y)-(Z)-2-(1-carboxy-1-methylethoxyimino)acetamido] -3-[5-(heterocycle)thiomethylpy-rrolidin-3-ylthio]methyl-3-cephem-4-carboxylic acid (14~18) having aminothiazol carboxymethylethoxy-imino group on the C-7 position and (heterocycle) thiomethyl pyrrolidinthiomethyl group on the C-3 position of the cephem ring were synthesized. These compounds were tested for antimicrobial activity in vitro against Gram(+) and Gram(-) bacteria. Compounds 15 and 16 showed remarkable antibacterial activity against Salmonella typhimurium TV119 and Alcalienes faecalis KCTC1004, but most of compounds showed lower activity than cefotaxime.

• 생약학회지
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• 제32권4호통권127호
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• pp.292-296
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• 2001

The Radix of Peucedanum japonicum (Umbelliferae) has been used for dispelling wind-damp, headache, chills and wind cold. In order to evaluate to quality of it, the method for the quantitative determination of peujaponiside $(peucedanol\;7-O-{\beta}-D-apiofuranosyl(1{\rightarrow}6)-{\beta}-D-glucopyranoside)$ as standard compound has been developed. Peujaponiside is a major compound of Peucedani Radix. It was analyzed by HPLC using the solvent system of 15% $CH_3CN$. The amount of peujaponiside from Peucedani Radix are in the range 0.14% (n=20).

• 대한화학회지
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• 제18권3호
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• pp.215-220
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• 1974

저자들은 tetrahedrane생성의 전구체인 t-butenedial bistosylhydrazone의 입체적인 구조를 연구할 목적으로 이의 유사한 구조인 ${\alpha},{\beta}$위치에 이중결합을 가지고 있는 몇 가지 phenylhydrazone을 합성하고 이들의 형태 및 배위를 nmr spectra의 해석으로부터 구명했다. 벤젠용매와 aliphatic solvent(CC14, DMSO)에서의 chemical shift의 차이로 부터 이들 물질이 syn-configuration을 가지고 있음을 알았으며 spin-spin coupling constant 로부터 이들 물질의 형태를 고찰하였다.

• 한국치위생학회지
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• 제16권5호
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• pp.733-740
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• 2016

Objectives: The purpose of this study was to investigate the relationship among the factors of communication ability according to self-awareness and other-awareness in some dental hygiene students. Methods: A self-reported questionnaire was completed by 260 dental hygiene students in Gwangju and Jeonnam from June 14 to 28, 2016. After explanation of the purpose of the study, an informed consent was written by the students. The effect size was calculated by $G^*power$ 3.1 program. The study instruments comprised the general characteristics of the subjects, self-awareness, other-awareness, and communication ability. Data were analyzed by independent test, one way ANOVA, $Scheff{\acute{e}}$ test, stewise multiple regression test, and Pearson's correlation test using SPSS 18.0. Results: Communication ability had a significant positive correlation with self-awareness(r=0.427, p<0.001) and other-awareness (r=0.460, p<0.001). The higher level of self-awareness and other-awareness was proportional to communication ability. The influencing factors of communication ability included private self-awareness(${\beta}=0.227$), public self-awareness(${\beta}=0.170$), social anxiety(${\beta}=0.182$), and external other-awareness(${\beta}=0.282$). Conclusions: To improve the communication ability in the dental hygiene students, it is important to improve self-awareness and other-awareness. The implementation of communication skill in the curriculum will enhance the dental hygiene students competency.

• 전기의세계
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• 제14권3호
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• pp.28-33
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• 1965

This experiment is based on "the feasible improvement studies for an eliminating device of the static electricity which applies the ionizing effect of beta radiation." In order to accomplish this object, the following problems were necessarily considered to investigate and to determine. The efficiency of the elimination of static electricity was determined by means of measuring the ion current between electrically charged plates with micro-ammeter. The effects of various factors, i.e., the distance between charged plate and radiation source, the activity of radiation source, the electric otential and the area of the charged plate, the shape of the source housing, the lining of backscattering material (Pb) on the source housing surface and blowing of ionized air, on the static electricity eliminating efficiency were studied. The beta radiation sources used in this experiment were S$^{35}$ and Sr$^{90}$ -Y$^{90}$ . It was revealed that ion current increased with source activity, the electric potential and area of the plates, the lead (Pb) lining on the surface of the source housing and the velocity of the ionized air blowing. As one could expect the S$^{35}$ was more effective to increase the ion current since it is known to be a higher specific ionization source than Sr$^{90}$ -Y$^{90}$ . The detailed result and performance of the eliminating device of the static electricity are described here.ibed here.